徐琳 教授

流行病学系




办公电话



电子邮件
xulin27@mail.sysu.edu.cn



一、学术简历
【学习经历】
1. 2010～2012 于香港大学公共卫生学院获得流行病学博士学位
2. 2008～2010 于香港大学公共卫生学院获得流行病学硕士学位
3. 2007～2008 于香港大学公共卫生学院获得公共卫生学硕士学位
4. 2000～2005 于中山大学公共卫生学院预防医学系获得学士学位
【工作经历】
1. 2017～至今 在中山大学公共卫生学院任职教授
2. 2015～2016年在香港大学公共卫生学院任职研究助理教授
3. 2012～2014年在香港大学公共卫生学院任职博士后
4. 2005～2007 于广州市第十二人民医院任职医师
二、社会兼职
（1）2015年至今担任香港大学荣誉助理教授，博士生联合导师
（2）2018年至今担任中华预防医学会流行病学分会青年委员会委员
（3）2019年至今担任广东省预防医学会流行病学专业委员会委员
（4）2018年至今担任中山大学附属第五医院兼职教授（客座教授）
（5）2018年至今担任广东省营养学会营养与慢病管理专业委员会委员
（6）2019年至今任广东省康复医学会脑卒中康复专业委员会副主任委员
（7）2008年至今以来担任了超过20份重要国际医学期刊的审稿人，包括Lancet Diabetes & Endocrinology，BMJ，Journal of Clinical Endocrinology and Metabolism，BMC Medicine, International Journal of Epidemiology，Journal of Epidemiology and Community Health，Neuroepidemiology，Stroke等等。

三、主要承担或参与的课题
（1）国家自然科学基金（“长寿重要相关因素及其作用机制研究”专项项目），**，基于遗传和环境多维度构建和验证健康衰老表型预测模型的队列研究，2020/01～2022/12，90万元，在研，主持
（2）国家“十三五”科技重大专项课题（增补课题），2018ZX**-003-003，乙肝及肝癌诊断及监测新型血清标记物在慢性HBV患者中的推广应用研究，2019/01-2020/12，211.01万元，在研，（增补课题）负责人
（3）国家“十三五”科技重大专项课题，2018ZX**，广东艾滋病、病毒性肝炎和结核病社区综合防治研究，2018/01-2020/12，3361.99万元，在研，参与（项目骨干）
（4）国家重点研发计划“精准医学研究”重点专项，SQ2017YFSF090036，华南区域自然人群慢性病前瞻性队列研究，2018/01-2021/12，1951万，在研，参与（项目骨干）

（5）广东省自然科学基金，2018A，血睾酮与缺血性心脏病：结合孟德尔随机化分析的人群前瞻性队列研究，2018/01-2020/12，10万，在研，主持
（6）香港健康医学研究基金（HMRF），**，A prospective study of Southern Chinese dietary pattern, foods and nutrients with cardiovascular disease mortality（中文题目：南中国膳食模式、食物及营养素对心血管疾病及死亡的前瞻性队列研究，2016/04-2017/03， 53万港币，已结题，主持
（7）香港大学研究资助基金，6，Establishment of cardiovascular risk prediction score in middle-age to older Chinese people（中文题目：建立中老年人心血管疾病的预测公式），2016/01-2016/12， 15.0万港币，已结题，主持
（8）香港健康医学研究基金（HMRF），**，Do common liver virus infections(HAV, HBV and HCV) contribute to high diabetes risk in China?（中文题目：常见肝病毒感染是否可引起中国高糖尿病患病率？），2014/04-2015/03， 70.1万港币，已结题，主持
（9）香港大学研究资助基金，6， Progression of carotid intima-media thickness and related cardiovascular outcomes in older Chinese people （中文题目：颈脉内膜-中层厚度的进展对心血管事件发生的影响），2014/01-2014/12， 5.23万港币，已结题，主持

四、近期发表的主要文章：近10年在国内外发表论文接近100篇，其中SCI论文约70篇，平均影响因子超过4分.部分代表性论著如下：
Xu L, Lam TH(*), Jiang CQ(*), Zhang WS, Zhu F, Jin YL, Woo J, Cheng KK, Thomas GN. Egg consumption and the risk of cardiovascular disease and all-cause mortality: Guangzhou Biobank Cohort Study and meta-analyses. Eur J Nutr. 2019; 58(2): 785-796.
Jiang CQ, Xu L(*), Lam TH(*), Jin YL, Sen Zhang W, Zhu F, Thomas GN and Cheng KK. Glycaemic measures and risk of mortality in older Chinese: the Guangzhou Biobank Cohort Study. The Journal of Clinical Endocrinology & Metabolism. 2019. doi: 10.1210/clinem/dgz173.
Wang T and Xu L(*). Circulating Vitamin E Levels and Risk of Coronary Artery Disease and Myocardial Infarction: A Mendelian Randomization Study. Nutrients. 2019;11:2153.
Ma XQ, Jiang CQ(*), Xu L(*), Zhang WS, Zhu F, Jin YL, Thomas GN and Lam TH. Sleep quality and cognitive impairment in older Chinese: Guangzhou Biobank Cohort Study. Age Ageing. 2019;49(1):119-124. doi: 10.1093/ageing/afz120.
Xu L, Lam TH. The Stage of Obesity Epidemic Model: Learning from Tobacco Control and Advocacy for a Framework Convention on Obesity Control. J Diabetes 2018;10:564-571.
Wang T, Jiang CQ(*), Xu L(*), Zhang WS, Zhu F, Jin YL, Thomas GN, Cheng KK, Lam TH. White blood cell count and all-cause and cause-specific mortality in the Guangzhou biobank cohort study. BMC public health, 2018;18(1), 1232.
Duan CW, Xu L(*). Testosterone and androstanediol glucuronide among men in NHANES III. BMC Public Health. 2018;18(1):339.
Lam TH (#), Xu L(#), Jiang CQ(*), Zhang WS, Zhu F, Jin YL, Thomas GN, Cheng KK. High relative risk of all-cause mortality attributed to smoking in China: Guangzhou Biobank Cohort Study. PLoS One. 2018;13(4):e**.
Xu L, Borges MC, Hemani G, Lawlor DA. The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study. Diabetologia. 2017;60(11):2210-2220.
Xu L (*), Hao YT. Effect of handgrip on coronary artery disease and myocardial infarction: a Mendelian randomization study. Sci Rep. 2017;7(1):954.
Xu L (*), Lin SL, Schooling CM: A Mendelian randomization study of the effect of calcium on coronary artery disease, myocardial infarction and their risk factors. Sci Rep 2017, 7:42691.
Xu L, Lam TH, Jiang CQ, Zhang WS, Jin YL, Zhu T, Zhu F, Thomas GN and Cheng KK. Adiposity and incident diabetes within 4 years of follow-up: the Guangzhou Biobank Cohort Study. Diabet Med. 2017;34:1400-1406.
Xu L, Jiang CQ, Lam TH, Zhang WS, Zhu F, Jin YL, Thomas GN, Cheng KK and Schooling CM. Mendelian randomization estimates of alanine aminotransferase with cardiovascular disease: Guangzhou Biobank Cohort study. Hum Mol Genet. 2017;26:430-437.
Xu L, Jiang CQ, Schooling CM, Zhang WS, Cheng KK and Lam TH. Liver enzymes as mediators of association between obesity and diabetes: the Guangzhou Biobank Cohort Study. Annals of epidemiology. 2017;27:204-207.
Yang S(#), Xu L(#), He Y, Jiang C, Jin Y, Cheng KK, Zhang W and Lam TH. Childhood secondhand smoke exposure and pregnancy loss in never smokers: the Guangzhou Biobank Cohort Study. Tob Control. 2017;26:697-702.
Xu L, Lam TH, Jiang CQ., Zhang WS, Jin YL, Zhu T, Thomas GN, Cheng KK. Changes in adiposity in an older Chinese population in rapid economic transition. Obesity, 2016;24(10), 2217-2223.
Jiang CQ, Chan YH, Xu L(*), Jin YL, Zhu T, Zhang WS, Cheng KK, Lam TH. (2016) Smoking and serum vitamin D in older Chinese people: cross-sectional analysis based on the Guangzhou Biobank Cohort Study. BMJ Open. 2016;6(6):e010946.
Xu L, Jiang CQ, Cheng KK, Au Yeung SL, Zhang WS, Lam TH(#) and Schooling CM. Alcohol Use and Gamma-Glutamyltransferase Using a Mendelian Randomization Design in the Guangzhou Biobank Cohort Study. PloS one, 2015;10, e**.
Xu L, Jiang CQ, Schooling CM(*), Zhang WS, Cheng KK, Lam TH. Liver enzymes and incident diabetes in China: a prospective analysis of 10,764 participants in the Guangzhou Biobank Cohort Study. JECH. 2015;69(11):1040-1044.
Lam TH(#), Xu L(#), Schooling CM(*), Chan WM, Lee SY, Leung GM. Smoking and mortality in a prospective cohort study of older chinese in Hong Kong. Addiction. 2015;110(3):502-510.
Xu L, Jiang CQ, Lam TH(*), Zhang WS, Cherny SS, Thomas GN, Cheng KK. Sleep duration and memory in the elderly chinese: Longitudinal analysis of the Guangzhou Biobank Cohort Study. Sleep. 2014;37:1737-1744
Xu L, Jiang CQ, Schooling CM(*), Zhang WS, Cheng KK, Lam TH. Prediction of 4-year incident diabetes in older Chinese: Recalibration of the Framingham diabetes score on guangzhou biobank cohort study. Preventive Medicine. 2014;69C:63-68
Xu L, Au Yeung SL, Kavikondala S, Leung GM, Schooling CM(*). Estradiol concentrations in young healthy US versus Chinese men. American journal of human biology: the official journal of human biology council 2014;26(4),565-569.
Xu L, Au Yeung SL, Kavikondala S, Leung GM, Schooling CM(*). Testosterone concentrations in young healthy us versus Chinese men. American journal of human biology: the official journal of human biology council. 2014;26(1):99-102.
Xu L, Freeman G, Cowling BJ, Schooling CM(*). Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials. BMC Medicine. 2013;11:108.
Xu L, Schooling CM(*), Chan WM, Lee SY, Leung GM, Lam TH. Smoking and hemorrhagic stroke mortality in a prospective cohort study of older Chinese. Stroke. 2013;44(8):2144-2149.
Zhang WS(#), Xu L(#), Schooling CM(*), Jiang CQ, Cheng KK, Liu B and Lam TH. Effect of alcohol and aldehyde dehydrogenase gene polymorphisms on alcohol-associated hypertension: the Guangzhou Biobank Cohort Study. Hypertension research. 2013;36(8):741-746.
Xu L, Chan WM, Hui YF, Lam TH(*). Association between HbA1c and cardiovascular disease mortality in older Hong Kong Chinese with diabetes. Diabetic Medicine 2012;29(3):393-8.
Xu L, Jiang CQ, Lam TH(*), Bao B, Cheng KK, Thomas GN. Plasminogen activator inhibitor-1 and HbA1c defined prediabetes: the Guangzhou Biobank Cohort Study-CVD. Clinical Endocrinology (Oxf) 2011;74(4):528-31.
Xu L, Jiang CQ, Lam TH(*), Thomas GN, Zhang WS, Cheng KK. Passive smoking and aortic arch calcification in older Chinese never smokers: the Guangzhou Biobank Cohort Study. Intternational Journal Of Cardiology 2011;148(2):189-93.
Xu L, Jiang CQ, Lam TH(*), Yue XJ, Lin JM, Cheng KK, Liu B, Li Jin Y, Zhang WS and Thomas GN. Arterial stiffness and left-ventricular diastolic dysfunction: Guangzhou Biobank Cohort Study-CVD. Journal Of Human Hypertension 2011;25(3):152-8.
Xu L, Jiang CQ, Lam TH(*), Zhang WS, Thomas GN, Cheng KK. Dose-response relation between physical activity and cognitive function: guangzhou biobank cohort study. Annals Of Epidemiology 2011;21(11):857-63.
Xu L, Jiang CQ, Lam TH(*), Liu B, Jin YL, Zhu T, Zhang WS, Cheng KK and Thomas GN. Short or long sleep duration is associated with memory impairment in older Chinese: the Guangzhou Biobank Cohort Study. Sleep 2011;34(5):575-80.
Xu L, Jiang CQ, Lam TH(*), Cheng KK, Yue XJ, Lin JM, Zhang WS and Thomas GN. Impact of impaired fasting glucose and impaired glucose tolerance on arterial stiffness in an older Chinese population: the Guangzhou Biobank Cohort Study-CVD. Metabolism 2010;59(3):367-72.
Xu L, Jiang CQ, Lam TH(*), Lin JM, Yue XJ, Cheng KK, Liu B, Jin YL, Zhang WS, Thomas GN. The metabolic syndrome is associated with subclinical atherosclerosis independent of insulin resistance: the Guangzhou Biobank Cohort Study-CVD. Clinical Endocrinology (Oxf) 2010;73(2):181-8.
Xu L, Jiang CQ, Lam TH(*), Thomas GN, Zhang WS, Cheng KK. Aortic arch calcification and vascular disease: the Guangzhou Biobank Cohort Study. Cardiology 2010;117(4):260-4.
Xu L, Jiang CQ, Lam TH(*), Yue XJ, Cheng KK, Liu B, Jin YL, Zhang WS and Thomas GN. Brachial-ankle pulse wave velocity and cardiovascular risk factors in the non-diabetic and newly diagnosed diabetic Chinese: Guangzhou Biobank Cohort Study-CVD. Diabetes Metabolism Research & Review 2010;26(2):133-9.
Lam TH and Xu L. Commentary: Fundamental limitations of meta-analysis of cohort studies, epidemiological challenges and the stage of obesity epidemic. Int J Epidemiol. 2016. (DOI. 10.1093/ije/dyw309)
Schooling CM, Xu L, Zhao J, Au Yeung SL. Norms hide causes-the example of testosterone. Int J Epidemiol. 2014; 43(6): 1987-8.
Schooling CM, Leung GM, Xu L. Promotion of "low t" and the role of testosterone clinical trials. JAMA internal medicine. 2014; 174(2): 305-6.
Schooling CM, Lin X. Testosterone and cardiovascular disease. The Lancet Diabetes & Endocrinology. 2014;2(8):612. doi: 10.1016/S2213-8587(170138-X.
Xu L, Au Yeung SL and Schooling CM. Does the optimal BMI really vary by age and sex? International journal of epidemiology. 2016;45:285-6.
Xu L, Schooling CM. Differential risks in men and women for first and recurrent venous thrombosis: the role of genes and environment: comment. Journal of thrombosis and haemostasis : JTH. 2015; 13(5): 884-6.
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五、研究生培养情况:?自2012年以来平均每年培养3-4名硕士研究生，自2015年以来担任香港大学博士生联合导师，2016年以来担任中山大学博士生导师
六、招生专业:?慢性病流行病学
七、获奖情况
2008 获贺达理教授奖(Professor Anthony Hedley Prize for Master of Public Health), 香港大学(年级总分第一名，优秀毕业论文奖)
2011获龍榮軾教授及朱淑濂女士研究生奖学金(YS and Christabel Lung Postgraduate Scholarship), 香港大学
2011年参与项目《广州生物库中老年队列的建立与常见慢性重大疾病的相关因素研究》，研究团队获中华预防医学会科学进步奖二等奖
2012再次获龍榮軾教授及朱淑濂女士研究生奖学金(YS and Christabel Lung Postgraduate Scholarship), 香港大学
2014年参与项目《广州生物库中老年队列的建立与常见慢性重大疾病的相关因素研究》，研究团队获广东省科学技术进步奖二等奖
2015年获香港大学/美国中华医学基金会（University of Hong Kong/China Medical Board)联合基金资助