个人简历


梁斌，男，汉族，1969年7月生，四川宜宾人，研究生学历，博士学位，副教授，1993年7月参加工作，无党派群众。现任汕头大学医学院细胞生物学与遗传学教研室副教授、生物医学研究中心副主任、硕士生导师。2008-2011年在美国杜兰大学（Tulane University）和俄克拉荷马大学（University of Oklahoma）进行博士后研究工作，目前为中华医学会医学细胞生物学学会会员；中国细胞生物学会会员；中国生物化学与分子生物学会会员；国家自然科学基金和省自然科学基金评审专家；人卫出版社本硕七年制器官-系统整合教材《人体分子与细胞基础》编委。目前研究领域为基因表观遗传调控对肿瘤、心血管病等疾病发病的影响机制，已在ATVB，Am J Cancer Res，Clinical Science等杂志发表第一作者和通迅作者文章12篇。


近年发表文章

1. Zikai Chen , Xuhong Song, Qidong Li, Lingzhu Xie, Tangfei Guo, Ting Su, Chang Tang, Xiaolan Chang, Bin Liang* and Dongyang Huang*.(共同通讯作者) Androgen Receptor-Activated Enhancers Simultaneously Regulate Oncogene TMPRSS2 and lncRNA PRCAT38 in Prostate Cancer. Cells. 2019, 9; 8(8).
2. Hongjin Liang, Xina Xie*, Xuhong Song, Meihui Huang, Ting Su, Xiaolan Chang, Bin Liang*, Dongyang Huang*. (共同通讯作者)Orphan nuclear receptor NR4A1 suppresses hyperhomocysteinemia-induced hepatic steatosis in vitro and in vivo. FEBS Lett. 2019, 593(10):1061-1071.
3. Lingzhu Xie, Xuhong Song, Hao Lin, Zikai Chen, Qidong Li, Tangfei Guo, Tian Xu, Ting Su, Man Xu, Xiaolan Chang, LongKun Wang, Bin Liang*, Dongyang Huang*.(共同通讯作者) Aberrant activation of CYR61 enhancers in colorectal cancer development. J Exp Clin Cancer Res. 2019 22; 38(1):213.
4. Meihui Huang, Xina Xie, Xuhong Song, Songgang Gu, Xiaolan Chang, Tin Su, Bin Liang*, Dongyang Huang*.(共同通讯作者) MiR-506 Suppresses Colorectal Cancer Development by Inhibiting Orphan Nuclear Receptor NR4A1. J Cancer. 2019, 9;10(15):3560-3570.
5. 吕社民，边惠洁等. 人体分子与细胞基础。 人民卫生出版社2018年第一版。（ISBN 978-7-117-27221-6,全国高等学校本硕七年制器官-系统整合教材，本人主编第十四章《脂质代谢》）
6. Dan Guo, Xuhong Song, Tangfei Guo, Songgang Gu, Xiaolan Chang, Ting Su, Xianghong Yang, Bin Liang*, Dongyang Huang*. Vimentin acetylation is involved in SIRT5-mediated hepatocellular carcinoma migration. Am J Cancer Res. 2018, 1;8(12):2453-2466.
7.Longkun Wang, Xina Xie, Xuhong Song, Ting Su, Xiaolan Chang, Man Xu, Bin Liang*, Dongyang Huang*.(共同通讯作者) Upregulation of miR-200b Inhibits Hepatocellular Carcinoma Cell Proliferation and Migration by Targeting HMGB3 Protein. Technol Cancer Res Treat. 2018, 1;17:**06475.
8. Xina Xie, Xuhong Song, Song Yuan, Haotao Cai, Yequn Chen, Xiaolang Chang, Bin Liang*, Dongyang Huang*.(共同通讯作者) Histone acetylation regulates orphan nuclear receptor NR4A1 expression in hypercholesterolaemia. Clin Sci (Lond). 2015, 129(12):1151-61.
9. Xuxia Sui, Yanmin Liu, Qi Li, Gefei Liu, Xuhong Song, Zhongjin Su, Xiaolan Chang, Yingbi Zhou, Bin Liang*, Dongyang Huang*. (共同通讯作者)Oxidized low-density lipoprotein suppresses expression of prostaglandin E receptor subtype EP3 in human THP-1 macrophages. PLoS One. 2014, 21;9(10): e110828.
10. Xuhong Song, Dongyang Huang, Yanmin Liu, Xiaokang Pan, Jin Zhang, Bin Liang*.(通讯作者) AMP-activated protein kinase is required for cell survival and growth in HeLa-S3 cells in vivo. IUBMB Life. 2014; 66(6): 415-23.
11. Bin Liang, Shuangxi Wang, Qilong Wang, Wencheng Zhang, Benoit Viollet, Yi Zhu, Minhui Zou*. (第一作者) Aberrant endoplasmic reticulum stress in vascular smooth muscle increases vascular contractility and blood pressure in mice deficient of AMP-activated protein kinase-α2 in vivo. Arterioscler Thromb Vasc Biol. 2013; 33(3):595-604.
12. Bin Liang, Xuhong Song, Gefei Liu, Rui Li, Jianpin Xie, Lifeng Xiao, Mudan Du, Qiaoxia Zhang, Xiaoyuan Xu, Xueqiong Gan, Dongyang Huang*.(共同第一作者) Involvement of TR3/Nur77 translocation to the endoplasmic reticulum in ER stress-induced apoptosis. Exp Cell Res. 2007;313(13):2833-44.
* 通讯作者


近年获得研究基金及课题


1）国家自然科学基金面上项目：长链非编码RNA调控AMPK活性在高血压血管重塑过程中的作用机制研究。项目批准号**。
2） 广东省自然科学基金自由申请项目：长链非编码RNA PRKAG2-AS1在高血压血管重塑中的调控作用。项目批准号 2014A。



作为课程主讲教师之一讲授课程