个人简历


焦晓阳，医学博士，主任技师。汕头大学医学院硕士生导师。丹麦科技大学/加拿大Alberta大学/Toronto大学访问****； 以第一作者或通讯作者发表SCI文章20多篇，主持多个省部级科研课题。
E-mail: xyjiao@stu.edu.cn


已发表文章


已发表的SCI论文：（*：通讯作者)
1） Huanzhu Chen, Chun Lin, Zhiqiang Fan, Wenjun Yu , Manxiong Cao, Changwen Ke, Xiaoyang Jiao*. Serum cytokines and clinical features in patients with fever and thrombocytopenia syndrome. Clinica Chimica Acta, 494 (2019) 22–30.
2) Chun Lin, Huanzhu Chen, Ping He, Yazhen Li, Changwen Ke, Xiaoyang Jiao *. Etiology and characteristics of community-acquired pneumonia in an influenza epidemic period Comparative Immunology, Microbiology and Infectious Diseases, 64 (2019) 153–158.
3) Huanzhu Chen, Huilan Weng, Meirui Lin, Ping He, Yazhen Li, Qingdong Xie, Changwen Ke, and Xiaoyang Jiao*. The Clinical Significance of FilmArray Respiratory Panel in Diagnosing Community-Acquired Pneumonia. BioMed Research International, Vol.2017, Article ID **, 6 pages https://doi.org/10.1155/2017/**.
4) Shan-shan Liu, Xiaoyang Jiao, Sheng Wang, Wen-zhe Su, Ling-zhi Jiang, Xin Zhang, Chang-wen Ke & Ping Xiong. Susceptibility of influenza A(H1N1)/pdm2009, seasonal A(H3N2) and B viruses to Oseltamivir in Guangdong, China between 2009 and 2014. Scientific RepoRts | 7: 8488 | DOI:10.1038/s41598-017-08282-6.
5) Yazhen Li, Qiancheng Qiu, Zhiqiang Fan, Ping He, Huanzhu Chen, Xiaoyang Jiao*.
Th17 cytokine profiling of colorectal cancer patients with or without enterovirus 71 antigen
expression. Cytokine 107 (2018) 35–42.
6) Zhicheng Fan, Qiaoxin Zhang, Huanzhu Chen, Ping He, Yazhen Li, Mengya Si, Xiaoyang Jiao*. Circulating microRNAs as a biomarker to predict therapy efficacy in hepatitis C patients with different genotypes. Microbial Pathogenesis 112 (2017) 320–326.
7) Jing-cheng Zhu, Meng-ya Si, Ya-zhen Li, Huan-zhu Chen, Zhi-cheng Fan, Qing-dong Xie and Xiao-yang Jiao*. Circulating tight junction proteins mirror blood-brain-barrier integrity in leukaemia central nervous system metastasis. Hematol Oncol 2017; 35: 365–373.
8) Xiaoyang Jiao, Zhicheng Fan, Huanzhu Chen, Ping He, Yazhen Li, Qiaoxin Zhang, Changwen Ke. Serum and exosomal miR-122 and miR-199a as a biomarker to predict therapeutic efficacy of hepatitis C patients. Journal of Medical Virology, 2017 DOI 10.1002/jmv.24829.
9) Huanzhu Chen, Huilan Weng, Meirui Lin, Ping He, Yazhen Li, Qingdong Xie, Changwen
Ke, and Xiaoyang Jiao*. The Clinical Significance of FilmArray Respiratory Panel in
Diagnosing Community-Acquired Pneumonia. BioMed Research International, 2017, Article ID **, 6 pages.
10) Yue-Ting Tang, Ping He, Ya-Zhen Li, Huan-Zhu Chen, Xiao-Lan Chang, Qing-Dong Xie and Xiao-Yang Jiao*. Diagnostic value of platelet indices and bone marrow megakaryocytic parameters in immune thrombocytopenic purpura. Blood Coagulation and Fibrinolysis 2017, 28:83–90.
11) Jinghong Chen, Xuehua Wang, Ping He, Yazhen Li, Mengya Si, Zhichen Fan, Xiaolan
Chang, Qindong Xie, and Xiaoyang Jiao*. Viral Etiology, Clinical, and Laboratory Features of Adult Hemophagocytic Lymphohistiocytosis. Journal of Medical Virology, 2016, 88:541–
549.
12) Tao Lu, Xiaoyang Jiao (co-first author), Mengya Si, Ping He, Jinbo Zou, Shuping Zhang,
and Kang Zeng. The Correlation of Serums CCL11, CCL17, CCL26, and CCL27 and
Disease Severity in Patients with Urticaria. Disease Markers,Volume 2016, Article ID **, 11 pages.
13) Yue-Ting Tang, Xiao-Yang Jiao*, Xiao-Lan Chang and Dong-Yang Huang*. Risk factors for the eva luation of potential central nervous system metastasis in Burkitt’s lymphoma: a case study and literature review. Hematol Oncol 2016; 34: 36–41.
14) Xiao-Yang Jiao, Rineke H. G. Steenbergen and D. Lorne Tyrrell. The use of human umbilical cord blood serum is beneficial for the continuous production of hepatitis C virus. Journal of General Virology. (2016), 97, 3248–3252.
15) Xiao-Yang Jiao, Zhi-chen Fan, Ya-zhen Li, Yue-ting Tang and Chang-wen Ke. Clinical and laboratory features parameters of human granulocytic anaplasmosis (HGA) in patients admitted to hospital in Guangdong Province, China. Tropical Doctor, 1–5 2015
doi:10.1177/9772.
16) Xiaoyang Jiao, Ping He, Yazhen Li, Zhicheng Fan, Mengya Si, Qingdong Xie, Xiaolan
Chang, and Dongyang Huang. The Role of Circulating Tight Junction Proteins in
eva luating Blood Brain Barrier Disruption following Intracranial Hemorrhage. Disease Markers, Volume 2015, Article ID 860120, 12 pages.
17) Meng-Ya Si, Zhi-Cheng Fan, Ya-zhen Li ,Xiao-Lan Chang, Qing-Dong Xie, Xiao-Yang
Jiao. The prognostic significance of serum and cerebrospinal fluid MMP-9, CCL2 and
sVCAM-1 in leukemia CNS metastasis. J Neurooncol (2015) 122:229–244.
18) Li Guo, Fang Jiang, Yue-Ting Tang, Meng-Ya Si, and Xiao-Yang Jiao*. The Association of
Serum Vascular Endothelial Growth Factor and Ferritin in Diabetic Microvascular Disease. Diabetes technology& therapeutics. 16, 4, 2014.
19) Fang Jiang, Wen-jun Yu, Xue-hua Wang, Yue-Ting Tang, Li Guo, and Xiao-Yang Jiao*
Regulation of hepcidin through GDF-15 in cancer-related anemia. Clinica Chimica Acta,
DOI:10.1016/j.cca.2013.10.015.
20) Tang, YT, Jiang, F, Guo, L, Si, MY, Jiao, XY*. Expression and significance of
vascular endothelial growth factor A and C in leukemia central nervous system metastasis. Leuk Res 2013, 37:359-366.
21) Tang YT, Jiang F, Guo L, Si MY, Jiao XY*. The soluble VEGF receptor 1 and 2
expression in cerebral spinal fluid as an indicator for leukemia central nervous system metastasis. J Neurooncol 2013; 112 (3): 329-38.
22) Jiang F, Tang YT, Guo L, Jiao XY*. The role of insulin-like growth factor I and hypoxia inducible factor 1alpha in vascular endothelial growth factor expression in type 2 diabetes. Ann Clin Lab Sci. 2013, 43(1):37-44
23) Xue-hua Wang, Pan-Pan Cheng, Fang Jiang, Xiao-Yang Jiao *. The effect of hepatitis B virus infection on hepcidin expression in hepatitis B patients. Ann Clin Lab Sci. 2013，43(2):126-134.
24) Cheng PP, Sun ZZ, Jiang F, Tang YT, Jiao XY*. Hepcidin expression in patients with acute leukaemia. Eur J Clin Invest，2012，42: 517-25.
25) Jiang, F, Sun, Z Z, Tang, Y T, Xu, C, Jiao, X Y*. Hepcidin expression and iron parameters change in Type 2 diabetic patients. Diabetes Res Clin Pract. 2011, 93: 43-48.
26) Pan-pan Cheng，Xiao-yang Jiao*, Xue-hua Wang, Jing-hua Lin, Ying-mu Cai. Hepcidin in anemia of chronic disease and anemia of chronic disease concomitant iron-deficiency anemia. Clinical and Experimental Medicine. 2010, 11:33-42.
27) Xiao-yang Jiao，Yan-qing Shen, Kang-sheng Li. The correlation between cytokine production by cerebral cortical glial cells and brain lateralization in mice. Neuromodulation. 2008, 11:23-32.
28) Yuanchun Huang, Qing Peng, Fen Yao, Yuanshu Qian, Yingmu Cai, Xiao-yang Jiao and Dexing Hua. Resistant phenotypes and genotypes of clinical isolates of multidrug-resistant Enterococcus faecium in a teaching hospital in Shantou, China African Journal of Microbiology Research.2010, 4(23), 2508-2512.
29) Xiao-shan Liu, Jikai Jiang*, Xiao-yang Jiao et al. Lycorine induces apoptosis and down-regulation of Mcl-1 in human leukemia cells. Cancer Letters.2009; 274:16-24.
30) Xiao-shan Liu, Jikai Jiang*, Xiao-yang Jiao et al. Matrine-induced apoptosis in leukemia U937 cells: Involvement of caspases activation and MAPK-independent pathways. Planta Medica 2006; 72: 501-506.

国内核心期刊以第一作者发表文章
1.抗生素诱导内毒素释放对术后感染患者IL-6水平的影响。中国热带医学杂志，
2008，7：1139-1141。
2.抗生素诱导内毒素释放对感染患者T淋巴细胞免疫功能的影响。 国外医学临床生物化学与检验学分册，2005，7：395-397
3.小鼠神经胶质细胞培养上清IL-6水平与脑不对称的关系。中国神经科学杂志，2004，9：373－375。
4 .CD7在急性白血病中的表达及临床意义探讨。国外医学临床生物化学与检验学分册，2005，3：184-185。
5.低增生型骨髓增生异常综合征与再生障碍性贫血的临床和细胞形态学比较。广东医学，2003，6：36－37
6 .恶性组织细胞增生症临床和病理分析。实用医学杂志，2002，8：837－838
7.静脉注射免疫球蛋白的免疫调节机制。汕头大学医学院学报，2003，9：173－176

国内期刊以通讯作者发表文章
1: 唐月汀,焦晓阳. 血管内皮生长因子C在恶性肿瘤转移中的作用与临床研究. 汕头大学医学院学报, 2012,25(3): 176-178.
2: 王雪华,降芳,焦晓阳. 血小板血管生成调节蛋白在慢性粒细胞白血病中的研究. 汕头大学医学院学报, 2011,24(2): 113-115
3: 降芳,焦晓阳. 血管内皮生长因子在白血病中的研究进展.汕头大学医学院学报, 2010,23(2): 118-121
4: 孙真真,姚芬,焦晓阳. 铜绿假单胞菌适应性及毒力相关基因分析. 汕头大学医学院学报, 2010.23(1): 58-60,64.
5: 黄源春,钱元恕,焦晓阳.透明质酸酶在细菌致病机制中的作用. 中国感染与化疗杂志 2008,8(3): 235-238.
6: 程盼盼,焦晓阳. Hepcidin研究进展. 汕头大学医学院学报, 2008,21(4): 238-240


科研

主持的科研项目有
1． 2018年，汕头市科技计划项目：“宏基因组学对肠道病原微生物流行趋势的预测模型建立的研究”；
2． 2017年，国家科技部科技改革与发展专项项目“寨卡病毒致病机制及其防控策略研究”；子课题负责人；
3． 2016年， 广东省防控寨卡病毒病科技攻关专项，子课题负责人；
4． 2015年，广东省高水平大学重点学科建设“感染性疾病研究与防治”项目子课题：致“发热伴血小板减少症候群”病原体快速检测方法的建立及分子流行病学研究；
5． 2014年， 汕头大学创新强校工程重大项目培育计划： VEGF和MMPs影响脑血管内皮细胞紧密连接蛋白结构和功能在白血病中枢神经系统转移中的作用；
6． 2012年2月――2013年2月：与牛津大学－汕头大学临床医学研究合作单位（Shantou –Oxford university clinic research unit: SOCRU）合作的课题:Sero-preva lence Of Enterovirus71 Infection In Children In Shantou City, Guangdong, China.
7． 2010年广东省科技计划项目（项目编号：2010B，）：
8． 2009年广东省自然基金项目（（项目编号：9**0043，课题已结题））：
9． 2005年广东省自然基金课题：屎肠球菌透明质酸酶Hy-1基因的研究；

10． 2008汕头市重点科技项目：免疫性血小板减少症血小板膜糖蛋白Ⅱb/Ⅲa测定的意义（项目编号：汕府科：〔2008〕85号）。
11. 2007汕头市重点科技项目：肥大细胞在慢性粒细胞白血病急变中的作用机制（项目编号：汕府科：〔2007〕76号）。



主要参加的项目有
2010年国家自然科学基金：槐属中药及生物碱抗肿瘤作用机制研究。(项目编号：**)


教学

1 .2014年2月至今：细胞生物学理论课和实验课的教学工作；护理系健康评估课程（全
英教学）

2 .自1998年开始参加汕头大学医学院临床诊断学的教学工作,分别负责临床医学专业7年制本硕班、5年制本科及夜大等多层次学生的大课和实验课教学;（全英或双语教学）

3. 2007 年获汕头大学医学院临床诊断学全英教学教师资格；

至2007年开始，担任汕头大学医学院硕士生导师, 已连续12年招收硕士生，共培养全日制研究生12名，在职研究生8名。