个人简介

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职称：教授
学科专业：病理生理学
研究方向：
1. 脑部微环境、神经胶质细胞功能与神经退行性疾病
2. 神经退行性疾病的早期诊断、发病机制及治疗干预
3. 神经炎症与记忆损伤修复关系
4. 中药有效成分防治脑功能疾病
行政职务：病理生理学系副主任
电子邮箱：lhzhu@jnu.edu.cn
个人简介：
朱丽红、女，医学博士、博士后，教授，硕士生导师，博士后合作导师，现任暨南大学基础医学与公共卫生学院病理生理学系副主任。
广东省病理生理学重点学科脑的功能与疾病研究方向的学术骨干梯队成员，被纳入省、市等多项人才培养计划, 注重将基础医学与临床医学、信息光子学、生命科学等跨学科合作，从临床发掘实际科学问题，解决关键科学与技术瓶颈问题，注重构建多元化的发展。近年，已主持、参加30余项各类项目研究，包括国家自然科学基金项目、973计划与省部级科研课题等，横、纵向经费逾400万；在“Brain Behav Immun”,“Molecular and Cellular Neuroscience”，“Oxid Med Cell Longev”等国内外杂志发表研究论文30余篇，多次在国际会议及国家级病理生理学年会做专题报告和大会发言，为本学科科研的中坚力量。主编专著1本。申请发明专利2项。承担本科及以上课程的中英文教学，组织指导学生开展科技创新等课外活动，开展医学生“产学研医”一体化实践教学，加强医学教学与生命健康知识的紧密结合，建立新型转化医学人才培养模式。

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学习经历

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2009.9-2011.9，暨南大学；
2006.9-2009.6，广州中医药大学

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工作经历

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2020.10-至今，暨南大学医学院病理生理学教研室，教授，硕士生导师，病理生理学系副主任；
2013.10-2020.09，暨南大学医学院病理生理教研室, 副教授，硕士生导师，病理生理学系副主任，病生实验室主任/机能实验室主任；
2011.09-2013.09，暨南大学医学院病理生理教研室, 讲师。

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主要论文

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1. Lihong Zhu,Renbing Qi,Huadong Wang,Wei Bi, Zhigang Wang, Qi Zeng, Yanru Zhao, Daxiang Lu. Luteolin protects PC12 cells from rotenone-induced apoptosis by decreasing cleaved caspase-3 expression. Neural Regen Res.2010,5(24):1870-1874.
2. Lihong Zhu, Bi W, Qi RB, Wang HD, Lu DX. Luteolin inhibits microglial inflammation and improves neuron survival against inflammation. Int J Neurosci. 2011,121(6):329-336.
3. Lihong Zhu, Wei Bi, Renbin Qi, Huadong Wang, Zhigang Wang, Qi Zeng, Yan-ru Zhao, Daxiang Lu. Luteolin reduces primary hippocampal neurons death induced by neuroinflammation. Neurol Res, 2011, 33(9):927-934.
4. LiHong Zhu, Wei Bi, XiaoDong Liu, JieFen Li, YingYa Wu, BiaoYan Du, YuHui Tan. Induction of apoptosis by evodiamine involves both activation of mitotic arrest and mitotic slippage. Oncology reports, 2011,26(6):1447-1455.
5. LiHong Zhu, Wei Bi, Dan Lu, ChanJuan Zhang, XiaoMing Shu,DaXiang Lu. Luteolin inhibits SH-SY5Y cell apoptosis through suppression of the NF-kB, MAPK and Akt pathways in LPS-stimulated co-cultured BV2 cells. Experimental and Therapeutic Medicine. 2014,7(5):1065-1070.
6. Lihong Zhu, Wei Bi, DAN LU, CHANJUAN ZHANG, XIAOMING SHU and DAXIANG LU Proteomic analysis of luteolin on lipopolysaccharide-stimulated BV2 microglia. Molecular Medicine Reports. Accepted on February 20, 2014.
7. Wei Bi*, Zhu L*(并列第一), Zeng Z, Jing X, Liang Y, Guo L, Shi Q, Xu A, Tao E. Investigations into the role of 26S proteasome non-ATPase regulatory subunit 13 (PSMD13) in neuroinflammation. Neuroimmunomodulation. 2014;21(6):331-337.
8. Wei Bi*, Zhu L*(并列第一), Xiuna Jing, Zhifen Zeng, Yanran Liang, Qiaoyun Shi, Enxiang Tao. Rifampicin improves neuronal apoptosis in LPS-stimulated co-cultured BV2 cells through inhibition of the TLR-4 pathway. Molecular Medicine Reports. 2014,10(4):1793-1799.
9. Lihong Zhu#, Wei Bi#, Dan Lu, Chanjuan Zhang, Xiaoming Shu, Huadong Wang, Renbing Qi , Qiaoyun Shi, Daxiang Lu*. Regulation of Ubiquitin-Specific Processing Protease 8 Suppresses Neuroinflammation Molecular and Cellular Neuroscience.2015,1(64):74-83.
10. Lu D, Xu A, Mai H, Zhao J, Zhang C, Qi R, Wang H, Lu D, Zhu L. The Synergistic Effects of Heat Shock Protein 70 and Ginsenoside Rg1 against Tert-Butyl Hydroperoxide Damage Model In Vitro. Oxid Med Cell Longev. 2015:437127.
11.Jiayi Zhao , Wei Bi , Shu Xiao , Xin Lan , Xiaofeng Cheng, Jiawei Zhang, Daxiang Lu, Wei Wei , Yanping Wang , Hongmei Li , Yongmei Fu, Lihong Zhu*. Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice. Scientific reports.2019,9:5790.
12.Wei Bi, Xin Lan, JiaWei Zhang, Shu Xiao, XiaoFeng Cheng, HuaDong Wang, DaXiang Lu, and Lihong Zhu*. USP8 ameliorates cognitive and motor impairments via microglial inhibition in a mouse model of sepsis-associated encephalopathy. Brain research. 2019.1719,40-48.
13.Zhao J, Bi W, Zhang J, Xiao S, Zhou R, Tsang CK, Lu D, Zhu L*. USP8 protects against lipopolysaccharide-induced cognitive and motor deficits by modulating microglia phenotypes through TLR4/MyD88/NF-κB signaling pathway in mice.Brain Behav Immun. 2020,4(19)31562
14. Wei Bi, Xiaofeng Cheng, Zhaohao Zeng, Ruiyi Zhou, Rixin Luo, Jiawei Zhang, Lihong Zhu*. Rifampicin ameliorates lipopolysaccharide-induced cognitive and motor impairments via inhibition of the TLR4/MyD88/NF-κB signaling pathway in mice. Neurological research.2020.**.
15. Lihong Zhu#, Qiongru Yuan#, Zhaohao Zeng, Ruiyi Zhou, Rixin Luo, Jiawei Zhang,Chikwan Tsang, Wei Bi*.Rifampicin suppresses Aβ accumulation through enhancing autophagy in models of lipopolysaccharide-induced cognitive decline.JOURNAL OF ALZHEIMER’S DISEASE.2021.79,1171-1184.

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学术著作

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1.《病理生理学实验指导及病例分析》，主编。

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获奖及荣誉

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1.入选暨南大学医学院“十二五”科技创新重点培养对象
2.入选暨南大学“优秀青年教师”支持计划（第二层次）
3.入选第八批广东省高等学校“千百十工程”校级培养对象
4.入选暨南大学“优秀青年教师”支持计划（第一层次）
5.入选广州市2015年珠江科技新星专项
6.入选广东省高等学校优秀青年教师培养计划人才专项
7.入选“暨南双百英才计划”暨南********支持计划（第一层次）
8.第六届本科课程教学竞赛获暨南大学医学院一等奖
9.第六届本科课程教学竞赛获暨南大学二等奖
10.2020年线上微课教学竞赛获基础医学院一等奖

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学术兼职

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1、国家自然科学基金评审专家
2、中国病理生理学会委员
3、广东省病理生理学会青年委员
4、广东省保健协会老年性痴呆医养融合分会委员

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