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厦门大学药学院导师教师师资介绍简介-吴云龙教授
本站小编 Free考研考试/2021-05-09
吴云龙博士,教授
个人简介:
吴云龙,男。2005年取得中国科学技术大学材料化学专业理学学士学位,2011年获新加坡国立大学生物工程博士学位。2010年-2012年在南洋理工大学材料科学与工程学院从事博士后工作。2012年应聘为厦门大学药学院助理教授,2014年聘为厦门大学药学院副教授,2019年聘为厦门大学药学院教授。主要研究方向:超分子自组装、基于环糊精的药物或基因载体设计、细胞牵引力显微镜。主要研究成果包括利用环糊精的分子识别操控其自组装为有序超分子结构,并探索超分子结构作为药物载体的优势。同时还对于细胞牵引力显微镜的开发用于观测细胞物理性能的实时动态变化过程有着浓厚的兴趣。近年,主持了国家自然科学基金面上基金项目(2019年**、2017年**)、福建省高校****科研人才培育计划项目(2018年)、国家自然科学基金青年基金项目(**)、福建省自然科学基金面上基金项目(2014J01063)、中央专项基本科研项目(、)、院长基金等多项科研项目。
教育及工作经历:
2001.09-2005.07: 中国科学技术大学, 材料化学学士;
2005.08-2011.06: 新加坡国立大学,生物工程博士;
2009.09-2010.03: 新加坡国立大学,生物工程系研究工程师;
2011.08:德国海德堡大学,合作研究者;
2010.05-2012.05: 新加坡南洋理工大学,材料科学与工程学院博士后;
2012.06-2014.07: 厦门大学药学院,助理教授;
2014.08-2019.07: 厦门大学药学院,副教授;
2019.08-至今: 厦门大学药学院,教授。
主持项目情况:
1. 国家自然科学基金面上基金项目,**,可原位改造CAR-T细胞用于实体瘤免疫治疗的基因缓释超分子水凝胶载体研究,2020/01-2023/12,在研,主持。
2. 国家自然科学基金面上基金项目,**,“可视化”温敏水凝胶缓释化疗药物/基因用于耐药性肝癌介入栓塞治疗的研究,2018/01-2021/12,在研,主持。
3. 福建省教育厅项目,闽教科[2018] 47号,福建省高校****科研人才培育计划,2018/08-2021/08,在研,主持。
4. 厦门大学校长基金项目,,新型肝癌经导管动脉内化疗(TACE)智能栓塞剂的研发,2017/01-2019/12,在研,主持。
5. 国家自然科学基金青年科学基金项目,**,基于超分子自组装的可示踪纳米粒子共载基因与化疗药物用于肿瘤治疗的研究,2014/01-2016/12,已结题,主持。
6. 福建省自然科学基金计划面上项目,2014J01063,新型纳米载体介导的多药物协同作用于肿瘤的研究,2014/01-2016/12,已结题,主持。
代表性论文(*通讯作者):
1. Wu, Y.-L.; Engl, W.; Hu, B.; Cai, P.; Leow, W. R.; Tan, N. S.; Lim, C. T.; Chen, X.* 2Nanomechanically Visualizing Drug-Cell Interaction at the Early Stage of Chemotherapy.2ACS Nano, 2017, 11(7): 6996-7005. (SCI impact factor: 13.942)
2. Chen, X.; Chen, Z.; Hu, B.; Cai, P.; Wang, S.; Xiao, S.; Wu, Y.-L.*; Chen, X.* 2Synergistic Lysosomal Activatable Polymeric Nanoprobe Encapsulating pH Sensitive Imidazole Derivative for Tumor Diagnosis.2Small, 2018, 14(9): **. [Highlighted byMaterials Views China: http://www.materialsviewschina.com/2018/02/27859/] (SCI impact factor: 10.856)
3. Cai, P.; Leow, W. R.; Wang, X.; Wu, Y.-L.*; Chen, X.* 2Programmable Nano-Bio Interfaces for Functional Biointegrated Devices.2Advanced Materials, 2017, 29(26): **. [Featured as Inside Back Cover] [Highlighted by Materials Views China: http://www.materialsviewschina.com/2017/05/24998/] (SCI impact factor: 25.809)
4. Liow, S. S.; Dou, Q.; Kai, D.; Sugiarto S.; Yu, C. Y. Y.; Kwok, R. T. K.; Chen, X.; Wu, Y.-L.*; Ong, S. T.; Kizhakeyil, A.; Verma N. K.; Tang, B. Z.; Loh, X. J.* 2Long-term Real-time in vivoDrug Release Monitoring with AIE Thermogelling Polymer.2Small, 2017, 13(7): **. [Featured as Back Cover] (SCI impact factor: 10.856)
5. Liu, X.; Chen, X.; Chua, M. X.; Li, Z.*; Loh, X. J.*; Wu, Y.-L.*2Injectable Supramolecular Hydrogels as Delivery Agents of Bcl-2 Conversion Gene for the Effective Shrinkage of Therapeutic Resistance Tumors.2Advanced Healthcare Materials, 2017, 6(11): **. [Featured as Front Cover] [Highlighted by Advanced ScienceNews: http://www.advancedsciencenews.com/cover-art-featuring-cancer-therapy-angiogenesis-tissue-engineering/] [Highlighted by Materials Views China: http://www.materialsviewschina.com/2017/07/25828/] (SCI impact factor: 6.270)
6. Chen, X.; Qiu, Y.-K.; Owh, C.; Loh, X. J.*; Wu, Y.-L.*2Supramolecular Cyclodextrin Nanocarriers for Chemo- and Gene Therapy towards the Effective Treatment of Drug Resistant Cancers.2Nanoscale, 2016, 8(45): 18876-18881. (SCI impact factor: 7.367)
7. Wu, Y.-L.; Putcha, N.; Ng, K.W.; Leong, D.; Lim, C.T.; Loo, S.C.; Chen, X.* 2Biophysical Responses upon the Interaction of Nanomaterials with Cellular Interfaces.2Accounts of Chemical Research, 2013, 46(3):782-791. (SCI impact factor: 20.268)
8. Wu, Y.-L.; Yin, H.; Zhao, F.; Li, J.* 2Multifunctional Hybrid Nanocarriers Consisting of Supramolecular Polymers and Quantum Dots for Simultaneous Dual Therapeutics Delivery and Cellular Imaging.2Advanced Healthcare Materials, 2013, 2(2): 297-301. (SCI impact factor: 6.270)
9. Wu, Y.-L.; Li, J.*2Synthesis of Supramolecular Nanocapsules Based on Threading Multiple Cyclodextrins over Polymer on Gold Nanoparticles.2Angewandte Chemie International Edition,2009, 48(21): 3842-3845. [Highlighted by Nature Asia-Pacific: http://www.nature.com/am/journal/2009/200908/full/am**a.html] (SCI impact factor: 11.994)
10. Luo, Z.; Jiang, L.; Yang, S.; Li, Z.*; Soh, W. M. W.; Zheng, L.*; Loh, X. J.*; Wu, Y.-L.*2Light-Induced Redox-Responsive Smart Drug Delivery System by Using Selenium-Containing Polymer@MOF Shell/Core Nanocomposite.2Advanced Healthcare Materials, 2019,DOI: 10.1002/adhm.. (SCI impact factor: 6.270)
11. Wu Y.-L.*; Li, Z* 2The Perspectives of Using Unimolecular Micelles in Nanodrug Formulation.2Therapeutic Delivery, 2019, 10(6): 333-335.
12. Liu, X.; Li, Z.; Loh, X.; Chen, K.; Li, Z.; Wu Y.-L.*2Targeted and Sustained Co-Release of Chemotherapeutics and Gene by Injectable Supramolecular Hydrogel for Drug-Resistant Cancer Therapy.2Macromolecular Rapid Communications, 2019, 40(5): **. (SCI impact factor: 4.078)
13. Cheng, H.; Fan, X.; Wu, C.; Wang, X.; Wang, L.-J.; Loh, X.-J.*; Li, Z.*; Wu Y.-L.*2Cyclodextrin-Based Star-Like Amphiphilic Cationic Polymer as a Potential Pharmaceutical Carrier in Macrophages.2Macromolecular Rapid Communications, 2019, 40(5): **. (SCI impact factor: 4.078)
14. Luo, Z.; Xu, Y.; Ye, E.; Li, Z.*; Wu, Y.-L.*2Recent Progress in Macromolecules Anchored Gold Nanoparticle Hybrid System for Therapeutic Applications.2Macromolecular Rapid Communications, 2019, 40(5): **. (SCI impact factor: 4.078)
15. Chen,Y.-P.; Zhang, J.-L.; Zou, Y.; Wu, Y.-L.*2Recent Advances on Polymeric Beads or Hydrogels as Embolization Agents for Improved Transcatheter Arterial Chemoembolization (TACE).2Frontiers in Chemistry, 2019,7: 408. (SCI impact factor: 3.782)
16. Xu,C.; Wu, Y.-L.*;Li, Z.*; Loh, X. J.* 2Cyclodextrin-Based Sustained Gene Release Systems: A Supramolecular Solution towards Clinical Applications.2Materials Chemistry Frontiers, 2019,3(2): 181-192.
17. Xue,K.;Wang, X.; Yong, P. W.; Wu, Y.-L.*;Li, Z.*; Loh, X. J.* 2Hydrogels as Emerging Materials for Translational Biomedicine.2Advanced Therapeutics, 2019, 2(1): **.
18. Jiang,L.;Luo, Z.; Loh, X. J.*; Wu, Y.-L.*;Li, Z.*; 2PHA-Based Thermogel as a Controlled Zero-Order Chemotherapeutic Delivery System for the Effective Treatment of Melanoma.2ACS Applied Bio Materials, 2019, DOI: 10.1021/acsabm.9b00467.
19. Guan, G.; You, M.; Liu, X.; Wu, Y.-L.*; Ye, E.*; Li, Z.* 2Tris-Stabilized MoS2Nanosheets with Robust Dispersibility and Facile Surface Functionalization.2Advanced Materials Interfaces, 2019, DOI: 10.1002/admi.. (SCI impact factor: 4.713)
20. Li,W.;Xu, C.; Li, S.; Chen, X.; Fan, X.; Hu, Z.; Wu, Y.-L.*;Li, Z.*; 2Cyclodextrin Based Unimolecular Micelles with Targeting and Biocleavable Abilities as Chemotherapeutic Carrier to Overcome Drug Resistance.2Materials Science and Engineering: C, 2019, 105: 110047. (SCI impact factor: 4.959)
21. Luo, Z.; Jiang, L.; Ding, C.; Hu, B.; Loh, X. J.; Li, Z.*; Wu, Y.-L.*2Surfactant Free Delivery of Docetaxel by Poly[(R)-3-hydroxybutyrate-(R)-3-hydroxyhexanoate]-Based Polymeric Micelle for Effective Melanoma Treatments.2Advanced Healthcare Materials, 2018,7(23): **. (SCI impact factor: 6.270)
22. Cheng, H.; Fan, X.; Wang, X.; Ye, E.; Loh, X. J.*; Li, Z.*; Wu, Y.-L.*2Hierarchically Self-Assembled Supramolecular Host-Guest Delivery System for Delivery of Chemotherapeutics to Drug Resistant Cancer Tumors.2Biomacromolecules, 2018, 19(6): 1926-1938. (SCI impact factor: 5.738)
23. Cheng, H.; Wu, Z.; Wu, C.; Wang, X.; Liow, S. S.;Li, Z.; Wu, Y.-L.* 2Overcoming STC2 Mediated Drug Resistance Through Drug and Gene Co-delivery by PHB-PDMAEMA Cationic Polyester in Liver Cancer Cells.2Materials Science and Engineering: C, 2018, 83: 210-217. (SCI impact factor: 4.959)
24. Fan,X.;Cheng, H.; Wang, X.; Ye, E.; Loh, X. J.; Wu, Y.-L.*;Li, Z.* 2Thermo-responsive Supramolecular Chemotherapy by “V”-shape Armed b-Cyclodextrin Star Polymer to Overcome Drug Resistance.2Advanced Healthcare Materials, 2018,7(7): **. (SCI impact factor: 6.270)
25. Liu,X.;Fan, X.; Jiang, L.; Loh, X. J.; Wu, Y.-L.*;Li, Z.* 2Biodegradable Polyester Unimolecular Systems as Emerging Materials for Therapeutic Applications.2Journal of Materials Chemistry B, 2018,6(35): 5488-5498. (SCI impact factor: 4.776)
26. Fan, X.; Cheng, H.; Wu, Y.; Loh, X. J.*; Wu, Y.-L.*; Li, Z.* 2Incorporation of Polycaprolactone to Cyclodextrin-based Nanocarrier for Potent Gene Delivery.2Macromolecular Materials and Engineering, 2018,303(9): **. (SCI impact factor: 2.690)
27. Chan, B.Q.Y.; Cheng, H.; Liow, S.S.; Dou, Q.; Wu, Y.-L.*; Loh, X.J.*; Li, Z.* 2Poly(carbonate urethane)-Based Thermogels with Enhanced Drug Release Efficacy for Chemotherapeutic Applications.2Polymers, 2018, 10(1): 89. (SCI impact factor: 2.935)
28. Wang, X.; Young, D. J.; Wu, Y.-L.*; Loh, X. J.* 2Thermogelling 3D Systems towards Stem Cell-Based Tissue Regeneration Therapies.2Molecules, 2018, 23(3): 553. (SCI impact factor: 3.098)
29. Wang, X.; Liow, S. S.; Wu, Q.; Li, C.; Owh, C.; Li, Z.*; Loh, X. J.*; Wu, Y.-L.* 2Codelivery for Paclitaxel and Bcl-2 Conversion Gene by PHB-PDMAEMA Amphiphilic Cationic Copolymer for Effective Drug Resistant Cancer Therapy.2Macromolecular Bioscience, 2017, 17(11): **. (SCI impact factor: 3.238)
30. Li, Z.*; Liu, X.; Chen, X.; Chua, M. X.; Wu, Y.-L.*2Targeted Delivery of Bcl-2 Conversion Gene by MPEG-PCL-PEI-FA Cationic Copolymer to Combat Therapeutic Resistant Cancer.2Materials Science and Engineering: C, 2017, 76: 66-72. (SCI impact factor: 4.959)
31. Yang, D.-P.; Liu, X.; Teng, C. P.; Owh, C.; Win, K. Y.; Lin, M.; Loh, X. J.; Wu, Y.-L.*; Li, Z.; Ye, E.* 2Unexpected Formation of Gold Nanoflowers by a Green Synthesis Method as Agents for a Safe and Effective Photothermal Therapy.2Nanoscale, 2017, 9(41): 15753–15759. (SCI impact factor: 7.367)
32. Zheng, C.; Gao, H.; Yang, D.-P.*; Liu, M.; Cheng, H.; Wu, Y.-L.*; Loh, X. J.*2PCL-based Thermo-gelling Polymers for In VivoDelivery of Chemotherapeutics to Tumors.2Materials Science and Engineering: C, 2017, 74: 110-116. (SCI impact factor: 4.959)
33. Fan, X.; Wang, X.; Cao, M.; Wang, C.; Hu, Z.; Wu, Y.-L.*;Li, Z.*; Loh, X. J.2“Y”-Shape Armed Amphiphilic Star-like Copolymer: Design, Synthesis and Dual-Responsive Unimolecular Micelle Formation for Controlled Drug Delivery.2Polymer Chemistry, 2017, 8(36): 5611-5620. (SCI impact factor: 5.375)
34. Wu, Y.-L.*; Wang, H.; Qiu, Y.-K.; Liow, S. S; Li, Z.; Loh, X. J.* 2PHB-based Gels as Delivery Agents of Chemotherapeutics for the Effective Shrinkage of Tumors.2Advanced Healthcare Materials, 2016, 5(20): 2679-2685. [Highlighted by http://www.advancedsciencenews.com/injectable-hydrogels-for-precise-chemotherapy/] (SCI impact factor: 6.270)
35. Wu, Y.-L.*; Wang, H.; Qiu, Y.-K.; Loh, X. J.* 2PLA-based Thermogel for the Sustained Delivery of Chemotherapeutics in a Mouse Model of Hepatocellular Carcinoma.2RSC Advances, 2016, 6(50): 44506-44513. (SCI impact factor: 3.108)
36. Li, J.-F.; Fang, H.; Yan, X.; Chang, F.-R.; Wu, Z.; Wu, Y.-L.*; Qiu, Y.-K.*2On-line Comprehensive Two-dimensional Normal-phase Liquid Chromatography × Reversed-phase Liquid Chromatography for Preparative Isolation of Toad Venom.2Journal of Chromatography A, 2016, 14556(22): 169-175. (SCI impact factor: 3.981)
37. Lin, N.; Chen, X.; Yan, S.; Wang, H.; Lu, Z.; Xia, X.; Liang, M.; Wu, Y.-L.*; Zheng, L.*; Cao Q.*; Ding, Z. 2An Aggregation-Induced Emission Based pH-sensitive Fluorescent Probe for Intracellular Acidity Sensing.2RSC Advances, 2016, 6(30): 25416-25419. (SCI impact factor: 3.108)
38. Wu, Y.-L.; Chen, X.; Wang, W.; Loh, X. J.* 2Engineering Bioresponsive Hydrogels towards Healthcare Applications.2Macromolecular Chemistry and Physics, 2016, 217(2): 175-188. [Featured in Front Cover] (SCI impact factor: 2.500)
39. Chen, W.-B.; Li, S.-Q.; Chen, L.-J.; Fang, M.-J.; Chen, Q.-C.; Wu, Z.; Wu, Y.-L.*; Qiu, Y.-K.* 2Online Polar Two Phase Countercurrent Chromatography × High Performance Liquid Chromatography for Preparative Isolation of Polar Polyphenols from Tea Extract in a Single Step.2Journal of Chromatography B, 2015, 997: 179-186. (SCI impact factor: 2.603)
40. Han,L.-Y.;Wu, Y.-L.; Zhu, C.-Y.; Wu, C.-S.*;Yang, C.-R.* 2Improved Pharmacokinetics of Icariin (ICA) within Formulation of PEG-PLLA/PDLA-PNIPAM Polymeric Micelles.2Pharmaceutics, 2019, 11(2): 51. (SCI impact factor: 4.773)
41. Kumar, J. N.*; Wu, Y.-L.; Loh, X. J.; Ho, N. Y.; Aik, S. X.; Pang, V. Y. 2The Effective Treatment of Multi-Drug Resistant Tumors with Self-Assembling Alginate Copolymers.2Polymer Chemistry,2019,10(2): 278-286. (SCI impact factor: 4.760)
42. Lui, Y. S.; Sow, W. T.; Tan, L. P.*; Wu, Y.-L.; Lai, Y.; Li, H.* 24D Printing and Stimuli-responsive Materials in Biomedical Applications.2Acta Biomaterialia,2019,92: 19-36. (SCI impact factor: 6.638)
43. Wang, T.; Qi, D.; Yang, H.; Liu, L.; Wang, M.; Leow, W. R.; Chen, G.; Yu, J.; He, K.; Cheng, H.; Wu, Y.-L.; Zhang, H.*; Chen, X.* 2Tactile Chemomechanical Transduction Based on an Elastic Microstructured Array to Enhance the Sensitivity of Portable Biosensors.2Advanced Materials,2019,31(1): **. (SCI impact factor: 25.809)
44. Cai, P.; Li, Z.; Keneth, E. S.; Wang, L.; Wan, C.; Jiang, Y.; Hu, B.; Wu, Y.-L.; Wang, S.; Lim, C. T.; Makeyev, E. V.; Magdassi, S.*; Chen, X.* 2Differential Homeostasis of Sessile and Pendant Epithelium Reconstituted in a 3D-Printed “GeminiChip”.2Advanced Materials,2019,DOI: 10.1002/adma.. (SCI impact factor: 25.809)
45. Cai, P.; Zhang, X.; Wang, M.; Wu, Y.-L.; Chen, X.* 2Combinatorial Nano?Bio Interfaces.2ACS Nano,2018,12(6): 5078-5084. (SCI impact factor: 13.709)
46. Wojnilowicz, M.; Besford, Q. A.; Wu, Y.-L.; Loh, X. J.; Braunger, J. A.; Glab, A.; Cortez-Jugo, C.; Caruso, F.*; Cavalieria, F.* 2Glycogen-Nucleic Acid Constructs for Gene Silencing in Multicellular Tumor Spheroids.2Biomaterials,2018,176: 34-49. (SCI impact factor: 8.806)
47. Shan, W.; Zhang, D.; Wu , Y.-L.; Lv, X.; Hu, B.; Zhou, X.; Ye, S.; Bi, S.; Ren, L.*; Zhang, X.* 2Modularized Peptides Modified HBc Virus-Like Particles for Encapsulation and Tumor-Targeted Delivery of Doxorubicin.2Nanomedicine: Nanotechnology, Biology and Medicine,2018,14(3): 725-734. (SCI impact factor: 6.500)
48. Cai, P.; Hu, B.; Leow, W. R.; Wang, X.; Loh, X. J.; Wu, Y.-L.; Chen, X.* 2Biomechano-Interactive Materials and Interfaces.2Advanced Materials,2018,30(31): **. (SCI impact factor: 25.809)
49. Hu, B.; Owh, C.; Chee, P. L.; Leow, W. R.; Liu, X.; Wu, Y.-L.; Guo, P.; Loh, X. J.*; Chen X.* 2Supramolecular Hydrogels for Antimicrobial Therapy.2Chemical Society Reviews,2018,47(18): 6917-6929. (SCI impact factor: 40.182)
50. Hu, B.;Leow, W. R.; Cai, P.; Li, Y.-Q.; Wu, Y.-L.; Chen, X.* 2Nanomechanical Force Mapping of Restricted Cell-To-Cell Collisions Oscillating between Contraction and Relaxation.2ACS Nano,2017,11(12): 12302-12310. (SCI impact factor: 13.709)
51. Wang, P.; Zeng, W.; Liu, J.; Wu, Y.-L.; Ma, Y.; Zeng, Z.; Pang, J.-y.*; Zhang, X.-k.; Yan, X.; Wong, A.; Zeng, J.-Z.* 2TRC4, an Improved Triptolide Derivative, Specifically Targets to Truncated Form of Retinoid X Receptor-alpha in Cancer Cells.2Biochemical Pharmacology, 2017, 124: 19-28. (SCI impact factor: 4.581)
52. Li, J.-F.; Yan, X.; Wu, Y.-L.; Fang, M.-J.; Wu, Z.; Qiu, Y.-K.*2Comprehensive Two-dimensional Normal-phase Liquid Chromatography × Reversed-phase Liquid Chromatography for Analysis of Toad Skin.2Analytica Chimica Acta, 2017, 962: 114-120. (SCI impact factor: 4.950)
53. Zeng W.; Zhang, C.; Cheng, H.; Wu, Y.-L.; Liu, J.; Chen, Z.; Huang, J. G.; Ericksen, R. E.; Chen, L.; Zhang, H.; Wong, A. S.*; Zhang, X.-k.; Han, W.; Zeng, J.-Z.* 2Targeting to the Non-genomic Activity of Retinoic Acid Receptor-Gamma by Acacetin in Hepatocellular Carcinoma.2Scientific Reports, 2017, 7: 348. (SCI impact factor: 4.259).
54. Hu, B.; Leow, W. R.; Amini, S.; Nai, B.; Zhang, X.; Liu, Z.; Cai, P.; Li, Z.; Wu, Y.-L.; Miserez, A.; Lim, C. T.; Chen, X.*2Orientational Coupling Locally Orchestrates a Cell Migration Pattern for Re-Epithelialization.2Advanced Materials, 2017, 29(29): **. (SCI impact factor: 25.809)
55. Wee, C. Y.; Liow, S. S.; Li, Z.; Wu, Y.-L.; Loh, X. J.* 2New Poly[(R)-3-hydroxybutyrate-co-4-hydroxybutyrate] (P3HB4HB)-Based Thermogels.2Macromolecular Chemistry and Physics, 2017, 218(17): **. (SCI impact factor: 2.500)
56. Wang, Y.-Q.; Tang, X.; Li, J.-F.; Wu, Y.-L.; Sun, Y.-Y.; Fang, M.-J.; Wu, Z.; Wang, X.-M.*; Qiu, Y.-K.*2Development of an On-Line Mixed-Mode Gel Liquid Chromatography × Reversed Phase Liquid Chromatography Method for Separation of Water Extract from Flos Carthami.2Journal of Chromatography A, 2017, 1519: 145-151. (SCI impact factor: 3.981)
57. Cai, P.; Layani, M.; Leow, W. R.; Amini, S.; Liu, Z.; Qi, D.; Hu, B.; Wu, Y.-L.; Miserez, A.; Magdassi, S.; Chen, X.* 2Bio-Inspired Mechanotactic Hybrids for Orchestrating Traction-Mediated Epithelial Migration.2Advanced Materials, 2016, 28(16): 3102-3110. (SCI impact factor: 25.809)
58. Yan, X.; Wang, L.-J.; Wu, Z.; Wu, Y.-L.; Liu, X.-X.; Chang, F.-R.; Fang, M.-J.*; Qiu, Y.-K.* 2New On-Line Separation Workflow of Microbial Metabolites viaHyphenation of Analytical and Preparative Comprehensive Two-Dimensional Liquid Chromatography.2Journal of Chromatography B, 2016, 1033-1034: 1-8. (SCI impact factor: 2.603)
59. Tay, C. Y.*; Wu, Y.-L.; Cai, P.; Tan, N. S.; Venkatraman, S. S.; Chen, X.; Tan, L. P.* 2Bio-inspired Micropatterned Hydrogel to Direct and Deconstruct Hierarchical Processing of Geometry-force Signals by Human Mesenchymal Stem Cells during Smooth Muscle Cell Differentiation.2NPG Asia Materials, 2015, 7(7): e199. (SCI impact factor: 9.157)
60. Loh, X. J.*; Wu, Y.-L.2Cationic Star Copolymers Based on β-Cyclodextrins for Efficient Gene Delivery to Mouse Embryonic Stem Cell Colonies.2Chemical Communications, 2015, 51(54): 10815-10818. [Featured in Back Cover] (SCI impact factor: 6.319)
61. Wang, D.; Chen, L.-J.; Liu, J.-L.; Wang, X.-Y.; Wu, Y.-L.; Fang, M.-J.; Wu, Z.; Qiu, Y.-K.* 2On-line Two-dimensional Countercurrent Chromatography × High Performance Liquid Chromatography System with a Novel Fragmentary Dilution and Turbulent Mixing Interface for Preparation of Coumarins from Cnidium monnieri.2Journal of Chromatography A, 2015, 1406: 215-223. (SCI impact factor: 3.981)
62. Hu, B.; Shi, W.; Wu, Y.-L.; Leow, W. R.; Cai, P.; Li, S.; Chen, X.* 2Orthogonally Engineering Matrix Topography and Rigidity to Regulate Multicellular Morphology.2Advanced Materials, 2014, 26(33): 5786-5793. (SCI impact factor: 25.809)
63. Yin, S.; Wu, Y.-L.; Hu, B.; Wang, Y.; Cai, P.; Tan, C. K.; Qi, D.; Zheng, L.; Leow, W. R.; Tan, N. S.; Wang, S.; Chen, X.* 2Three-dimensional Graphene Composite Macroscopic Structures for Capture of Cancer Cells.2Advanced Materials Interfaces,2014, 1(1): **. (SCI impact factor: 4.713)
64. Liu, J.-L.; Wang, X.-Y.; Zhang, L.-L.; Fang, M.-J.; Wu, Y.-L.; Wu, Z.; Qiu, Y.-K.* 2Two-dimensional Countercurrent Chromatography × High Performance Liquid Chromatography with Heart-cutting and Stop-and-go Techniques for Preparative Isolation of Coumarin Derivatives from Peucedanum praeruptorumDunn.2Journal of Chromatography A, 2014, 1374: 156–163. (SCI impact factor: 3.981)
65. Lam, C.R.; Tan, C.; Teo, Z.; Tay, C.Y.; Phua, T.; Wu, Y.-L.; Cai, P.Q.; Tan, L.P.; Chen, X.; Zhu, P.; Tan, N.S.* 2Loss of TAK1 Increases Cell Traction Force in a ROS-dependent Manner to Drive Epithelial-Mesenchymal Transition of Cancer Cells.2Cell Death & Disease, 2013, 4: e848. (SCI impact factor: 5.965)
66. Cai, L. L.; Ye, H. M.; Lv, X. N.; Wu, Y.-L.; Zhang, H. J.; Zheng, L. M.; Tzeng, C. M.* 225-(OH)VitD3, as a Risk Indicator in Diagnosis of Adenocarcinoma.2Current Drug Targets, 2013, 14(11): 1367-1376. (SCI impact factor: 3.236)
67. Wu, D.-C.*; Loh, X. J.; Wu, Y.-L.; Lay, C. L.; Liu, Y.*2’Living’ Controlled in situ Gelling Systems: Thiol-Disulfide Exchange Method toward Tailor-Made Biodegradable Hydrogels.2Journal of the American Chemical Society, 2010, 132(43): 15140-1514. (SCI impact factor: 13.858)
68. Loh, X. J.*; Zhang, Z.-X.; Mya, K. Y.; Wu, Y.-L.; He, C. B.; Li, J.*2Efficient Gene Delivery with Paclitaxel-Loaded DNA-Hybrid Polyplexes Based on Cationic Polyhedral Oligomeric Silsesquioxanes.2Journal of Materials Chemistry, 2010, 20(47): 10634-10642. (SCI impact factor: 6.101)
69. Loh, X. J.; Zhang, Z.-X.; Wu, Y.-L.; Lee, T. S.; Li, J.*2Synthesis of Novel Biodegradable Thermoresponsive Triblock Copolymers Based on Poly[(R)-3-hydroxybutyrate] and Poly(N-isopropylacrylamide) and Their Formation of Thermoresponsive Micelles.2Macromolecules, 2009, 42(1): 194-202. (SCI impact factor: 5.835)
70. Loh, X. J.; Wu, Y.-L.; Seow, W. T. J.; Norimzan, M. N. I.; Zhang, Z.-X.; Xu, F.-J.; Kang, E.-T.; Neoh, K.-G.; Li, J.*2Micellization and Phase Transition Behavior of Thermosensitive Poly(N-isopropylacrylamide)–Poly(e-caprolactone)–Poly(N-isopropylacrylamide) Triblock Copolymers.2Polymer, 2008, 49(23): 5084-5094. (SCI impact factor: 3.684)
71. Cui, H.*; Zhang, Z.-F.; Shi, M.-J.; Xu, Y.; Wu, Y.-L.2Light Emission of Gold Nanoparticles Induced by the Reaction of Bis(2,4,6-trichlorophenyl) Oxalate and Hydrogen Peroxide.2Analytical Chemistry, 2005, 77(19): 6402-6406. (SCI impact factor: 6.320)
Book Chapters
1. Luo, R.-C.; Wu, Y.-L.; EI-Newehy, M. 2The Industrial Production of PHA.2A Chapter in 2Polyhydroxyalkanoates (PHAs): Biosynthesis, Industrial Production and Applications in Medicine.2(Edited by L.-P. Wu) NOVA Science Publishers, ISBN: 978-1-63321-659-4, 2014, 133-140.
2. Luo, R.-C.; Wu, Y.-L.; EI-Newehy, M. 2Extraction and Purification of Polyhydroxyalkanoates.2A Chapter in 2Polyhydroxyalkanoates (PHAs): Biosynthesis, Industrial Production and Applications in Medicine.2(Edited by L.-P. Wu) NOVA Science Publishers, ISBN: 978-1-63321-659-4, 2014, 141-152.
3. Chen, K.; Yang, J.; Guo, S.; Chen, C.-H.; Luo, R.-C.; Wu, Y.-L.2Hydrogel Coatings for Heart Stents.2Materials Science and Technology (Wiley-VCH Verlag GmbH & Co. KGaA), 2019, DOI: 10.1002/78.mst0490.
联系方式:
地址:厦门市翔安区厦门大学药学院448室
电话:
Email:wuyl@xmu.edu.cn
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