李逐波，男，1963年生，博士，药理学教授，硕士生导师（体内药物分析方向[100704]、天然药物药理方向[0710Z1生物药学]）。从1991年起承担本科生和硕士研究生的《药理学》、《药物代谢动力学》、《高级药理学》、《体内药分与药代动力学》、《药学进展》等课程的教学工作。研究领域为化学药物制剂、以QSAR方法设计合成天然产物有效成分结构修饰物，并进行其药理学与生产的工业化研究。近年来，以中药有效成分等天然产物为模板，以模板化合物量子化学参数的变化对其生物效应的促进作用为基础对鱼腥草中的癸酰乙醛、大蒜中的大蒜新素、苦参中的苦参碱、蜂胶中的咖啡酸苯乙酯和黄芩中的黄芩甙等进行了新化学结构的设计、合成，筛选出部分生物活性高的物质。其中几种大蒜新素衍生物有很强的抗细菌、真菌、螨虫的和增强病毒疫苗免疫等效应，对前列腺癌细胞PC-3和肺癌细胞A549有明显的诱导凋亡作用;黄芩苷衍生物对肝癌细胞HepG2和HepG2细胞造模的裸鼠肿瘤有明显的诱导凋亡作用和肿瘤生长抑制作用；咖啡酸苯乙酯衍生物能显著改善实验鼠心脏冠状循环。针对药物应用缺陷的氟苯尼考衍生物等已经成功进行了工业化应用研究。先后主持省部级基金项目2项，攻关项目5项，重大专项1项，在研重庆市攻关项目2项、重大专项1项、横向项目4项。获3项省部级科技进步奖，近年来发表论文50余篇（其中SCI 收录28篇），申请中国发明专利16个,授权8个。先后成为四川省优秀青年骨干教师、重庆市首届优秀青年骨干教师、重庆市首届学术与技术带头人后备人选。重庆市司法局西南大学司法鉴定所司法鉴定人。
通讯地址：
西南大学药学院，重庆北碚，400716
电话: **(MP)
传真:
邮箱: zb63@163.com
主要专利：
1、体内速释的高水溶性氟苯尼考前药，公开号:CNA
2、低刺激性大蒜素衍生物及其合成方法和应用，2011授权
3、苦参碱磺酸钠及其制备方法，2011授权
4、N-芳烷基苯胺类化合物的合成方法，2013授权
5、一种新鱼腥草素钠注射液在治疗奶牛乳房炎中的应用，公开号:CNA
6、咖啡酸对硝基苯乙酯及其制备方法和应用，2013授权
7、畜禽注射用盐酸林可霉素冻干粉针剂及其制备方法，公开号： CNA
8、兽用土青注射液制备方法及临床应用，2013授权
9、兽用复方右旋糖酐铁注射液制备方法及对小鼠生长的影响,2012授权
10.枸橼酸苯海拉明的合成方法，公开号：CNA
11.黄芩甙铜配合物及其制备方法,公开号：CNA
12.蝎子草多糖的制备方法及其产品和应用，2013授权
13.枸橼酸苯海拉明口腔崩解片及其制备方法，2013授权
近几年的A类论文：
1.李逐波，叶小利，袁吕江，李学刚*.高效液相色谱法测定动物组织中鱼腥草素同系物的含量.分析化学. 2007,35(2),pp297-300
2.Zhu-Bo Li*, Yong-Huang Luo, Wen-Liang Dong, Jing Li and Hua Zuo N-benzyl-2-(2,6-dichlorophenoxy)acetamide.Acta Crystallographica Section E Structure Reports Online.2008,64,o1610
3.Zhu-Bo Li*, Hua Zuo, Wen-Liang Dong, Xiao-Yan He and Zhang-Bao Chen N-benzyl-2-(2-chloro-4-methylphenoxy)acetamide.Acta Crystallographica Section E Structure Reports Online.2008,64,o1609
4.Zhubo Li*, Xiaoyan He, Hua Zuo. Synthesis of novel analogues on the α-carbon of houttuyfonate and analysis on SAR of antibacterial activity with MOPAC.Medicinal Chemistry Research.2009,18(5),pp 362-372
5.Zhu-Bo Li*, Xiao-Yan He, Yong-Sheng Xie and Guang-Cheng Qin. N-Benzyl-2-(2-chloro-5-methylphenoxy)acetamide.Acta Crystallographica Section E Structure Reports Online.2008,64,o2426
6.Zhu-Bo Li*, Xiao-Yan He, Wen-Liang Dong and Dan-Dan Liao. 8-Chloro-4-cyclohexyl-2H-1, 4-benzoxazin-3(4H) –one.Acta Crystallographica Section E Structure Reports Online.2009,65,o762
7.Zhu-Bo Li*, Hao Yang, Yong-Sheng Xie and Chen-Guang Zhao. 4-Benzyl-7-chloro-2H-1,4-benzoxazin-3(4H)-one.Acta Crystallographica Section E Structure Reports Online.2009,65,o1019
8.Zhu-Bo Li*, Jing Li, Wen-Liang Dong, Hua Zuo and Xiao-Yan He. N-Cyclohexyl-2-(2,3-dichlorophenylsulfanyl) acetamide. Acta Crystallographica Section E Structure Reports Online.2009,65,o32
9.Ming-Jun Chen, Yang-Wu Fu, Wen-Liang Dong, Zhu-Bo Li* and Hua Zuo.N-Benzyl-2-(2,4-dichlorophenoxy) –acetamide.Acta Crystallographica Section E Structure Reports Online.2008,64,o1968
10.Fang-Kui Ren, Xiao-Yan He, Li Deng, Dong-Soo Shin, and Zhu-Bo Li*. Synthesis and Antibacterial Activity of 1,3-Diallyltrisulfane Derivatives.Bull. Korean Chem. Soc. 2009.30(3),pp 687-690
11.Hua Zuo, Zhu-Bo Li, Fang-Kui Ren, J.R. Falck, Meng Lijuan, Chuljin Ahn, Dong-Soo Shin*. Microwave-assisted one-pot synthesis of benzo[b][1,4]thiazin-3(4H)-ones via Smiles rearrangement. Tetrahedron.2008,64(41),pp9669-9674
12.Hua Zuo, Zhu-Bo Li, Wen-Liang Dong and Li-Ying Wang. N-cyclohexyl-2-(2,3-dichlorophenoxy)acetamide.Acta Crystallographica Section E Structure Reports Online.2008,64,o2288
13.Hua Zuo,Geo Jose,Zhu-bo Li,Bu-Hyun Moon,Dong-Soo Shin* and Manjunath Ghate*.Microwave-assisted synthesis of fluorinated coumarino sulfonamides.ARKIVOC.2008,2,pp 183-189
14.Hao Yang，Liang Fang，Zhu-Bo Li，Fang-Kui Ren，Li-Ying Wang， Xiao Tian， Dong-Soo Shin， Hua Zuo. Synthesis and in vitro antimicrobial activity of benzo[b][1,4]thiazin-3(4H)-ones via smiles rearrangement. Medicinal Chemistry Research. 2011, 20:93-100
15.Hao Yang H,Zhubo Li,Zuo H*,et al.A Facile C-N Bond Formation: One-Pot Reaction of Phenols and Amines via Smiles Rearrangement. SYNLETT, 2010,3:483-487
16.赵晨光，廖丹丹，何小燕，李逐波*.苦参碱肌肉注射给药在大鼠体内的药动学研究.中国中药杂志.2010,35(10):1315-1318
17.赵晨光，左华，廖丹丹，何小燕，李逐波*.盐酸头孢噻呋对苦参碱大鼠体内药动学的影响. 中国中药杂志.2010,35(14):1859-1861
18.Qingwang Liu, Di Zhao, Xijing Chen, Zhubo Li*, Ning Li, Deen-Han, Amer Talbi,Tarcisse Biwoele. Determination of Corosolic Acid, a Natural Potential Anti-Diabetes Compound, in Rat Plasma by High-Performance Liquid Chromatography-Mass Spectrometry and its Application to Pharmacokinetic and Bioavailability Studies. planta medica.2011,77(15):1707-11
19.刘衍季，何小燕，李逐波*,等.黄酮类金属配合物的生物活性研究进展.中国中药杂志，2012,37(13):1901-1904
20.刘衍季，何小燕，李逐波*,等. 黄芩苷铜和铝配合物的合成及其生物活性研究.中国中药杂志，2012,37(9):1296-1310
21.Min Chen,Xiaoyan Zhao,Zhubo Li*,et al. Effect of diallyl trisulfide derivatives on the induction of apoptosis in human prostate cancer PC-3 cells. Mol Cell Biochem,2012,363:75-84
22.Qin,GC, Chen,LX, Yang,P, Zuo,H, Li, ZB *.Synthesis of Water-Soluble Prodrug of Florfenicol. ASIAN JOURNAL OF CHEMISTRY,2011,23(11):5157-5158
23.Tian, X., Wang, L-Y., Xia, S., Li, Z-B., Liu, X-H., Yuan, Y., Fang, L., Zuo, H., Synthesis of 2H-benzo[b][1,4] oxazin-3(4H)-one derivatives as platelet aggregation inhibitors.Bioorganic & Medicinal Chemistry Letters ,2012,22(1):204-206
24.Hua Zuo, Zhu-Bo Li, Bao-Xiang Zhao,* et al. Highly Efficient Microwave-assisted Aminolysis of Epoxides in Water. Bull. Korean Chem. Soc. 2011, 32(8): 2965-69
25.Xiao Tian, Zhu-Bo Li, Hua Zuo*,et al. Smiles rearrangement for the synthesis of diarylamines. ARKIVOC,2011 (x):118-126
26.Jia-Zhou Zhou, Zhu-Bo Li, Hao Yang, Xiao-Yan He, Hua Zuo, et al. Synthesis of 2H-1,4-Benzoxazin-3(4H)-ones via Smiles Rearrangement. ASIAN JOURNAL OF CHEMISTRY,2011,23(7):2947-2950
27.Liang Fang, Hua Zuo, Zhu-Bo Li,et al. Synthesis of benzo[b][1,4]oxazin-3(4H)-ones via smiles rearrangement for antimicrobial activit. MED CHEM RES,2011,20(6):670-677
28.L. CHEN, X.Y. HE, K. ZHOU, D.F. LI, T.L. LIU, Z.H. WU,Z.B.LI *.Comparison of RP-HPLC and Non-aqueous Titration Method for Determination of Diphenhydramine Citrate and its Related Substances.Lat. Am. J. Pharm. 2012,31(8):1096-101
29.Li-juan Meng, B. V. D. Vijaykumar, Hua Zuo, Zhu-Bo Li, Gautam Dupati, Kiwan Jang,Dong-Soo Shin.Stereoselective synthesis of (3S,4R)- and (3R,4S)-4-(N-substituted-amino)-2,2-dimethyl-6-nitrochroman-3-ols via the microwave assisted regioselective ringopening of epoxides in the presence of neutral alumina.Tetrahedron: Asymmetry,2012,23:1029-1037
30.Xiaoyan HE, Junfeng YANG, Hua ZUO, Yonghuang LUO & Zhubo LI*.Effect of Diallyl Trisulfide Derivatives on the Activation of Macrophage-Mediated Cytotoxicity. Lat. Am. J. Pharm. 2013,32(1):107-112
31. Tianliang LIU , Li DENG, Qin DU , Li CHEN, Xiaohua LIU, Zhubo LI*. Novel Caffeic acid phenethyl ester (CAPE) analogues as immunoregulatory agents: synthesis and SAR study. Lat. Am. J. Pharm. 2013,32 (3): 329-34