刘志勇
职称：研究员

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实验室主页：http://liulab.genetics.ac.cn

研究方向：小麦抗病性和重要农艺性状的遗传改良和分子育种


刘志勇，博士，研究员，博士生导师
1996年和1999年中国农业大学获得硕士和博士学位，1999年至2004年在瑞士ETH Zurich和美国Hawaii Agriculture Research Center进行博士后研究，2004年回国到中国农业大学工作并获得国家****基金，2016年到中国科学院遗传与发育生物学研究所工作担任课题组长。
刘志勇博士课题组的主要研究方向是小麦基因组学、遗传学和育种，利用遗传学和基因组学手段解析小麦抗病性和重要农艺性状形成的遗传学基础，发掘小麦野生种、地方品种和育成品种中抗病基因和重要农艺性状基因/QTL及其优异等位变异，进行种质创新和新品种培育。
主要研究内容：
1.小麦抗病基因发掘、精细定位和图位克隆
小麦锈病（条锈病、叶锈病）、白粉病和叶枯病是严重危害小麦生产的重要病害。课题组收集国内外的小麦野生种、地方品种和育成品种，进行系统的抗病性鉴定和遗传分析，利用分子标记定位种质资源中的抗病基因。利用比较基因组学手段，应用高通量SNP分析和下一代测序手段对抗病基因进行精细定位和图位克隆，旨在解析小麦对重要真菌性病害的抗性遗传和分子机理，研究小麦抗病基因的遗传进化和变异机制，开发抗病基因功能标记应用于小麦分子育种。
2.小麦重要农艺性状基因/QTL定位、精细定位和图位克隆
小麦产量构成因素、株型（株高、叶片形态、茎杆质地等）和抗逆性（根系性状）是影响小麦产量的重要农艺性状。课题组以小麦遗传群体和自然群体为材料，利用高通量SNP分析和下一代测序技术进行遗传作图，对控制重要农艺性状的基因/QTL进行定位、精细定位和图位克隆，应用于小麦产量潜力的遗传改良和分子育种。
3.小麦种质创新和新品种培育
综合利用常规育种和分子育种技术手段，创制和培育适于我国小麦主产区的高产、抗病、抗逆、节水种质资源和新品种。
4.短柄草研究
以短柄草为对象，开展抗大麦条纹花叶病毒（BSMV）基因克隆及其与BSMV互作研究。
育成品种：
小麦新品种“农大1108”（豫审麦**号）主要育种人（第二完成人）
小麦新品种“农大399”（冀审麦**号）主要育种人（第二完成人）
小麦新品种“农大408”（京审麦**号）主要育种人（第二完成人）
小麦新品种“农大多系1号”（京审麦**号）主要育种人（第二完成人）
小麦新品种“农大413”（京审麦**号）主要育种人（第二完成人）
小麦新品种“农大318”（津审麦**号）主要育种人（第二完成人）
获得奖励：
小麦抗病优质多样化基因资源发掘、创新和利用。2015年度，国家科学技术进步二等奖（第二完成人）
小麦锈病和白粉病多样化抗源发掘、创新和利用。2010年度，教育部科技进步一等奖（第二完成人）
主要论文：（*通讯作者）
ShengnanZhai,ZhonghuHe,WeieWen,HuiJin,JindongLiu, Yong Zhang,ZhiyongLiu,XianchunXia (2016) Genome-wide linkage mapping of flour color？related traits and polyphenol oxidase activity in common wheat.TheorApplGenet 129:377-394
MeiyanLiu, LeiLei, CarolPowers,ZhiyongLiu, KimberlyG.Campbell,XianmingChen, RobertL.Bowden, BrettF.Carver,LiulingYan (2016)TaXA21-A1on chromosome 5AL is associated with resistance to multiple pests in wheat.TheorApplGenet 129:345-355
Ping Lu, Yong Liang,DelinLi,ZhengzhongWang,WenbinLi,GuoxinWang, Yong Wang,ShenghuiZhou,QiuhongWu,JingzhongXie,DeyunZhang,YongxingChen,MiaomiaoLi, Yan Zhang,QixinSun,ChengguiHan,ZhiyongLiu*(2016) Fine genetic mapping ofspot blotch resistance geneSb3in wheat (Triticumaestivum).TheorApplGenet 129:577-589
QiuhongWu,YongxingChen, Lin Fu,ShenghuiZhou,JiaojiaoChen,XiaojieZhao, Dong Zhang,ShuhongOuyang,ZhenzhongWang, Dan Li,GuoxinWang,DeyunZhang,ChengguoYuanLixinWang,MingshanYou, Jun Han,ZhiyongLiu*(2016) QTL mapping of flag leaf traits in common wheat using an integrated high-density SSR and SNP genetic linkage map.Euphytica208:337-351
Ping Lu,JinxiaQin,GuoxinWang,LiliWang,ZhenzhongWang,QiuhongWu,JingzhongXie, Yong Liang, Yong Wang,DeyunZhang,QixinSun,ZhiyongLiu*(2015) Comparative fine mapping of the Wax 1 (W1) locus inhexaploidwheat.TheorApplGenet 128(8):1595-1603
Yong Liang, De-Yun Zhang,ShuhongOuyang,JingzhongXie,QiuhongWu,ZhenzhongWang, Yu Cui, Ping Lu, Dong Zhang,Zi-JiLiu,JieZhu, Yong-Xing Chen, Yan Zhang, Ming-ChengLuo, Jan Dvorak,NaxinHuo,QixinSun, Yong-QiangGu,ZhiyongLiu*(2015) Dynamic evolution of resistance gene analogs in the orthologous genomic regions of powdery mildew resistance geneMlIW170inTriticumdicoccoidesandAegilopstauschii.TheorApplGenet 128(8):1617-1629
ZhenzhongWang,HanwenLi,DeyunZhang, LiGuo,JiaojiaoChen,YongxingChen,QiuhongWu,JingzhongXie, Yan Zhang,QixinSun, Jan Dvorak, Ming-ChengLuo,ZhiyongLiu*(2015) Genetic and physical mapping of powdery mildew resistance geneMlHLTin Chinese wheat landraceHulutou.TheorApplGenet 128:365-373
Qiu-Hong Wu, Yong-Xing Chen, Sheng-HuiZhou, Lin Fu, Jiao-Jiao Chen, Yao Xiao, Dong Zhang,Shu-HongOuyang, Xiao-JieZhao, Yu Cui, De-Yun Zhang, Yong Liang, Zhen-ZhongWang, Jing-ZhongXie, Jin-Xia Qin,Guo-XinWang, De-Lin Li, Yin-LianHuang, Mei-HuaYu, Ping Lu, Li-Li Wang, Ling Wang,HaoWang, Chen Dang,JieLi, Yan Zhang,Hui-RuPeng, Cheng-GuoYuan, Ming-Shan You, Qi-XinSun,Ji-RuiWang, Li-XinWang, Ming-ChengLuo, Jun Han,Zhi-Yong Liu*(2015) High-density linkage map construction and QTL mapping of grain shape and size in the wheat population Yanda1817 × Beinong6.PloSONE,10(2): e**
Dong Zhang,ShuhongOuyang,LiliWang, Yu Cui,QiuhongWu, Yong Liang,ZhenzhongWang,JingzhongXie,DeyunZhang, Yong Wang,YongxingChen, andZhiyongLiu*(2015) Comparative genetic mapping revealed powdery mildew resistance geneMlWE4derived from wild emmer is located in same genomic region ofPm36andMl3D232on chromosome 5BL. Journal of Integrative Agriculture14:603-609
ShuhongOuyang, Dong Zhang, Jun Han,XiaojieZhao, Yu Cui, Wei Song,NaxinHuo, Yong Liang,JingzhongXie,ZhenzhongWang,QiuhongWu,YongxingChen, Ping Lu,DeyunZhang,LiliWang,HuaSun,TsominYang, GabrielKeeble-Gagnere, RudiAppels,JaroslavDole？el, Hong-Qing Ling,MingchengLuo,YongqiangGu,QixinSun,ZhiyongLiu*(2014) Fine genetic mapping and toward physical mapping of powdery mildew resistance geneMlIW172originating from wild emmer(Triticumdicoccoides).PLoSONE9(6): e100160.
ZhenzhongWang, Yu Cui,YongxingChen,DeyunZhang, Yong Liang, Dong Zhang,QiuhongWu,JingzhongXie,ShuhongOuyang,DelinLi,YinlianHuang, Ping Lu,GuoxinWang,MeihuaYu,ShenghuiZhou,QixinSun,ZhiyongLiu*(2014) Comparative genetic mapping and genomic regioncollinearityanalysis of the powdery mildew resistance genePm41.TheorAppl. Genet.127:1741-1751
JingtingLi,ZhenzhongWang,HuiruPeng,ZhiyongLiu*(2014) A MITE insertion into the 3′-UTR regulates the transcription ofTaHSP16.9in common wheat. The Crop Journal 2:381-387
HaibinWu,JinxiaQin, Jun Han,XiaojieZhao,ShuhongOuyang, Yong Liang, Dong Zhang,ZhenzhongWang,QiuhongWu,JingzhongXie, Yu Cui,HuiruPeng,QixinSun,ZhiyongLiu*(2013) Comparative High-Resolution Mapping of the Wax Inhibitors Iw1 and Iw2 inHexaploidWheat.PLoSONE 8(12): e84691.
Li L, D Li, S Liu, X Ma, CR Dietrich, HC Hu, G Zhang,Z Liu, JZheng, G Wang, PSSchnable(2013) The maize glossy13 gene, cloned via BSR-SeqandSeq-Walking encodes a putative ABC transporter required for the normal accumulation ofepicuticularwaxes.PlosOne 8(12): e82333.doi:10.1371/journal.pone.**
ZijiLiu,JieZhu, Yu Cui, Yong Liang,HaibinWu, Wei Song, Qing Liu,TsominYang,QixinSun,ZhiyongLiu*(2012) Identification and Comparative Mapping of a Powdery Mildew Resistance Gene Derived from Wild Emmer (Triticumturgidumvar.dicoccoides) on Chromosome 2BS.TheorAppl. Genet 124:1041-1049
Yu Cui,MiYeonLee,NaxinHuo, Jennifer Bragg,LijieYan, Cheng Yuan, Cui Li, Sara J.Holditch,JingzhongXie, Ming-ChengLuo,DaweiLi,JialinYu, Joel Martin, WendySchackwitz, YongQiangGu, John P. Vogel, Andrew O. Jackson*ZhiyongLiu*, and David F. Garvin (2012) Fine mapping of theBsr1barley stripe mosaic virus resistance gene in the model grassBrachypodiumdistachyon.PlosOne 7(6): e38333.
MiYeonLee1,LijieYan, Florien A.Gorter, Brian Y.T Kim, Yu Cui,YueHu, Cheng Yuan, JessicaGrindheim, UmaGanesan,ZhiyongLiu,ChengguiHan,JialinYu,DaweiLi and Andrew O. Jackson (2012) A pathogenicity determinant overcomingBrachypodiumdistachyonBd3-1 resistance resides in the Triple Gene Block 1 movement protein of the Norwich strain ofBarley stripe mosaic virus. J.ofGeneral Virology 93:2529-2756
TilinFang, Kimberly G. Campbell,ZhiyongLiu,XianmingChen,AnminWan, Shan Li,ZijiLiu,ShuangheCao,YihuaChen, Robert L. Bowden, Brett F. Carver, andLiulingYan (2011) Stripe rust resistance in the wheat cultivarJaggeris due toYr17and a novel resistance gene. Crop Science51: 6: 2455-2465
Cheng Yuan, Cui Li,LijieYan, Andrew O Jackson,ZhiyongLiu,ChengguiHan,JialinYu,DaweiLi (2011)Ahigh throughputBarley Stripe Mosaic Virusvector for virus induced gene silencing in monocots and dicots.PLoSONE 6(10): e26468.
HongtaoZhang,HaiyingGuan,JingtingLi,ChaojieXie,XiayuDuan,YilinZhou,TsominYang,QixinSun,ZhiyongLiu*(2010) Genetic and comparative genomics mapping reveals that a powdery mildew resistance geneMl3D232originating from wild emmer co-segregates with an NBS-LRR analog in common wheat (TriticumaestivumL.).TheorAppl. Genet.121:1613-1621
The InternationalBrachypodiumInitiative (2010) Genome sequencing and analysis of the model grassBrachypodiumdistachyon. Nature 463:763-768
Andrea L. Blas, Ray Ming,ZhiyongLiu, Olivia J. Veatch, Robert E.Paull, Paul H. Moore,QingyiYu (2010) Cloning of papayachromoplastspecific lycopene β-cyclase,CpCYC-b, controlling fruit flesh color revealed conservedmicrosyntenyand a recombination hotspot. Plant Physiology 152:2013-2020
YanjieWang,HuiruPeng, Gang Liu,ChaojieXie,ZhongfuNi,TsominYang,ZhiyongLiuandQixinSun (2010)Identification and molecular mapping of a leaf rust resistance gene in spelt wheat landraceAltgold.Euphytica174:371-375
GenqiaoLi,TilinFang,HongtaoZhang,ChaojieXie,HongjieLi,TsominYang,EviatarNevo,TzionFahima,QixinSun,ZhiyongLiu*(2009) Molecular identification of a new powdery mildew resistance genePm41on chromosome 3BL derived from wild emmer (Triticumturgidumvar.dicoccoides).TheorApplGenet 119:531-539
WeiHua,ZijiLiu,JieZhu,ChaojieXie,TsominYang,YilinZhou,XiayuDuan,QixinSun,ZhiyongLiu*(2009) Identification and genetic mapping ofpm42, a new recessive wheat powdery mildew resistance gene derived from wild emmer (Triticumturgidumvar.dicoccoides).TheorApplGenet 119:223-230
Wei Song,ChaojieXie,JinkunDu,HaoXie, Qing Liu,ZhongfuNi,TsominYang,QixinSun,ZhiyongLiu*(2009)A‘one-marker-for-two-genes’ approach for efficient molecular discrimination ofPm12andPm21conferring resistance to powdery mildew in wheat. Molecular Breeding 23:357-363
HuaW,SoltanlooH., Lu, J,PuchalskiB, Frick M, Liu ZY,LarocheA,GaudetD (2008) Expression ofdefence-related genes in wheat carrying Lr34/Yr18 genes for adult plant resistance to leaf rust. Canadian Journal of plant pathology 30:368-369
XiaolingJi,ChaojieXie,ZhongfuNi,TsominYang,EviatarNevo,TzionFahima,ZhiyongLiu,QixinSun (2007) Identification and genetic mapping of a powdery mildew resistance gene in wild emmer (Triticumdicoccoides) accession IW72 from Israel.Euphytica159: 385-390
Wei Song,HaoXie, Qing Liu,ChaojieXie,ZhongfuNi,TsominYang,QixinSun,ZhiyongLiu*(2007) Molecular identification ofPm12-carrying introgression lines in wheat using genomic and EST-SSR markers.Euphytica158:95-102
Qing Liu,ZhongfuNi,HuiruPeng,WeiSong,ZhiyongLiu,QixinSun (2007) Molecular mapping of a dominant non-glaucousnessgene from synthetichexaploidwheat (TriticumaestivumL.).Euphytica155:71-78
HongjieLi, R. L. Conner,ZhiyongLiu,YiwenLi, Yu Chen,YilinZhou,XiayuDuan,TianminShen, Qin Chen, R. J. Graf, andXuJia(2007) Characterization of Wheat-Triticale Lines Resistant to Powdery Mildew, Stem Rust, Stripe Rust, Wheat Curl Mite, and Limitation on Spread of WSMV. Plant Disease 91(4)：368-374
YingyinYao,ZhongfuNi,YinhongZhang, Yan Chen,YuhuaDing,ZongfuHan,ZhiyongLiu,QixinSun (2005) Identification of Differentially Expressed Genes in Leaf and Root between Wheat Hybrid and Its ParentalInbredsUsing PCR-basedcDNASubtraction. Plant Molecular Biology 58(3):367-384
SusanSchenck, Heather M. Pearl,ZhiyongLiu, Paul H. Moore, and Ray Ming (2005) Genetic variation ofUstilagoScitamineapathotypesin Hawaii evaluated by host range and AFLP markers.Sugar Cane International.23(1):15-19

ZhiyongLiu, Paul H. Moore,HaoMa, Christine Ackerman, M.Ragiba,QingyiYu, P. Heather, Mina Kim, J. Charlton, J.I. Stiles, F.T. Zee, Andrew H. Paterson, Ray Ming. (2004) A primitive Y chromosome in papaya marks incipient sex chromosome evolution. Nature 427:348-352
HaoMa, Paul H. Moore,ZhiyongLiu, Mina S. Kim,QingyiYu, M.M.M. Fitch, T.Sekioka, Andrew H. Paterson, Ray Ming (2004) High-density linkage mapping revealed suppression of recombination at the sex determination locus in papaya. Genetics 166:419-436
DeniseSteiger, Paul H. Moore, F. Zee,ZhiyongLiu, Ray Ming (2003) Genetic relationship of macadamia cultivars and species revealed by AFLP markers.Euphytica132: 269-277
Deputy J. C., Ray Ming,HaoMa,ZhiyongLiu, M. M. M. Fitch, M. Wang, R.Manshardt, J. I. Stiles (2002) Molecular markers for sex determination in papaya (Caricapapaya L.).TheorApplGenet 106:107-111

ZhiyongLiu, Stephen O. Peter,MuhuaLong, U.Weingartner, Peter Stamp andOiliverKaeser. (2002). A PCR assay for rapid discrimination of cytoplasm types in maize.Crop Sci. 42:566-569

ZhiyongLiu,QixinSun,ZhongfuNi,EviatarNevo,TsominYang(2002) Molecular characterization of a powdery mildew resistance genePm30in wheat originating from wild emmer (Triticumturgidumvar.dicoccoides).Euphytica.123:21-29.
ZhongfuNi,QixinSun,ZhiyongLiu,LiminWu,XiaolingWang. (2000) Identification of a hybrid-specific expressed gene encoding novel RNA-binding protein in wheat seedling leaves using differential display of mRNA.MolGen Genet.263:934-938

ZhiyongLiu,QixinSun,ZhongfuNi,TsominYang (1999) Development of SCAR markers linked to thePm21gene conferring resistance to powdery mildew in wheat. Plant Breeding 118: 215-219

ZhiyongLiu,QixinSun,HongjieLi,ZhongfuNi,BorangTang,AidongYang,TsominYang,XuJia(1999) Molecular identification and marker assisted selection ofPm21gene conferring resistance to powdery mildew in wheat. Chinese Journal of Genetics 26:339-347
QixinSun,ZhongfuNi,ZhiyongLiu(1999) Differential gene expression between wheat hybrids and their parentalinbredsin seedling leaves.Euphytica106:117-123
QixinSun,ZhongfuNi,ZhiyongLiu,JianweiGao,TiechengHuang (1998) Genetic relationships and diversity among Tibetan wheat, common wheat and European spelt wheat revealed by RAPD makers.Euphytica99:205-211