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Precise genome editing without exogenous donor DNA via retron editing system in human cells

本站小编 Free考研考试/2022-01-02

Xiangfeng Kong1,,,
Zikang Wang2,
Renxia Zhang2,3,
Xing Wang1,
Yingsi Zhou2,
Linyu Shi1,
Hui Yang2,4,,
1. HUIGENE Therapeutics Inc., Shanghai, 200131, China;
2. Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China;
3. College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China;
4. Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology, Shanghai, 201210, China
Funds: This work was supported by HUIGENE Therapeutics Inc., the Basic Frontier Scientific Research Program of Chinese Academy of Sciences From 0 to 1 original innovation project (grant no. ZDBS-LYSM001), the R&D Program of China (Grant Nos. 2017YFC1001300 and 2018YFC2000100) and the CAS Strategic Priority Research Program (Grant No. XDB32060000).

Received Date: 2021-06-26
Publish Date:2021-11-12




Abstract



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http://www.protein-cell.org/article/exportPdf?id=7fc038ea-3cdb-4a18-bd85-e21d1527904b&language=en
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