FBXW7 E3 ubiquitin ligase: degrading, not degrading, or being degraded

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Huiyin Lan1,2,
Yi Sun1,3,
1 The Cancer Institute of the Second Affiliated Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou 310029, China;
2 Department of Radiation Oncology, Zhejiang Key Lab of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou 310022, China;
3 Division of Radiation and Cancer Biology, Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
Funds: This work is supported by the National Key R&D Program of China (2016YFA0501800) (YS), the National Natural Science Foundation of China (Grant No. 81572718) (YS).

Abstract

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