姓名：丁卫 性别：男 职称：教授 招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：遗传学(博) 遗传学(硕) 研究方向名称：肿瘤分子遗传学，基因治疗 电子信箱：weiding@ccmu.edu.cn


社会任职
个人简历
1. 198609-199107:北京医科大学基础医学系 学习
2. 199108-199611:北京医科大学生化与分子生物学系 助教
3. 199612-199908:美国爱荷华大学解剖系 研究助理
4. 199909-200512:美国爱荷华大学解剖与细胞生物学系 学习
5. 200512-200609:美国爱荷华大学解剖与细胞生物学系 博士后
6. 200612-201209:首都医科大学生化与分子生物学系 教授
7. 201209-201501:首都医科大学医学遗传学系 教授
8. 201501-201812:首都医科大学生物化学与分子生物学系 教授
9. 201901-:首都医科大学医学遗传与发育生物学系 教授
重要学术论文
1. Zhang R#, Cao L#, Cui M#, Sun Z, Hu M, Zhang R, Stuart W, Zhao X, Yang Z, Li X, Sun Y, Li S, Ding W*, Lou Z*, Rao Z.Adeno-associated virus 2 bound to its cellular receptor AAVR. Nat Microbio. 2019,4(4):675-682.SCI
2. Zhang R, Xu G, Cao L, Sun Z, He Y, Cui M, Sun Y, Li S, Li H, Qin L, Hu M, Yuan Z, Rao Z, Ding W, Rao Z, Lou Z*.Divergent engagements between adeno-associated viruses with their cellular receptor AAVR. Nat Commun. 2019,10(1):3760.
3. 5.Cui M, Lu Y, Tang C, Zhang R, Wang J, Si Y, Cheng S*, Ding W.A Generic Method for Fast and Sensitive Detection of Adeno-Associated Viruses Using Modified AAV Receptor Recombinant Proteins. Molecules. 2019,24(21):pii: E3973.
4. 黄文秋, 刘旭, 王俐勇, 程杉, 叶海虹,丁卫*.Windows操作系统下二代测序数据处理平台的建立及高通量信息分析标准流程在个人计算机上的实现. 中国生物化学与分子生物学报. 2019,35(6):687-692.核心期刊
5. Min Zhang*, Ting Yao, Mingtao Gao, Xiaofei Tang, Dong Yan, Chenguang Zhang#, Wei Ding#.Monitoring autophagic flux using p62/SQSTM1 based luciferase reporters in glioma cells. Exp Cell Res. 2018,363(1):84-94.SCI
6. Yue ZX, Gao RQ, Gao C, Liu SG, Zhao XX, Xing TY, Niu J, Li ZG, Zheng HY, Ding W*.The prognostic potential of coilin in association with p27 expression in pediatric acute lymphoblastic leukemia for disease relapse. Cancer Cell Int. 2018,18:106.SCI
7. Song Y#, Niu J#, Yue Z, Gao R, Zhang C, Ding W*.Increased chemo-sensitivity by knockdown coilin expression involved acceleration of premature cellular senescence in HeLa cells. Biochem Biophys Res Commun . 2017,489(2):123-129.SCI
8. Huang W, Zhang C, Cui M, Niu J, Ding W#.Inhibition of Bevacizumab-induced Epithelial-Mesenchymal Transition by BATF2 Overexpression Involves the Suppression of Wnt/β-Catenin Signaling in Glioblastoma Cells. Anticancer Res. 2017,37(8):4285-4294.SCI
9. Bai X#, Huang W, Zhang C, Niu J*, Ding W*.Discovery of a Regulatory Motif for Human Satellite DNA Transcription in Response to BATF2 Overexpression. Anticancer Res. 2016,36(3):1203-10.SCI
10. Yao T#, Zhang CG#, Gong MT, Zhang M, Wang L, Ding W*.Decorin-mediated inhibition of the migration of U87MG glioma cells involves activation of autophagy and suppression of TGF-β signaling. FEBS Open Bio. 2016,6(7):707-719.SCI
11. Hua Li#, Feng-Lan Zhang#, Wen-Jie Shi, Xue-Jia Bai, Shu-Qin Jia,Chen-Guang Zhang*, Wei Ding*.Immobilization of FLAG-Tagged Recombinant Adeno-Associated Virus 2 onto Tissue Engineering Scaffolds for the Improvement of Transgene Delivery in Cell Transplants . PLOS ONE. 2015,10(6):e**:1-15.SCI
12. 张敏，张晨光，丁卫*.外泌体及其在肿瘤诊疗中的意义. 生理科学进展. 2014,45（5）:372-378.核心期刊
13. Yan SF#, You HJ, Xing TY, Zhang CG*, Ding W*..HDAC Inhibitor Sodium Butyrate Augments the MEF2C Enhancement of Nampt Expression under Hypoxia.. Curr Pharm Des. 2014,20(11):1604-13.SCI
14. 周子玉， 姚婷， 张晨光， 丁卫*.新型核心蛋白聚糖靶向性重组腺相关病毒的制备与鉴定. 中国生物化学与分子生物学报. 2014,30（9）:933-941.核心期刊
15. Ren X#, Zhang T#, Gong X, Hu G, Ding W*, Wang X*.AAV2-mediated striatum delivery of human CDNF prevents the deterioration of midbrain dopamine neurons in a 6-hydroxydopamine induced parkinsonian rat model. Exp Neurol. 2013,248:148-56.SCI
16. 岳志霞#,张晨光, 丁卫*.卡哈尔体——功能复杂的核内细胞器. 中国细胞生物学学报. 2013,35(10):1525-1532.核心期刊
17. 邢天禹，丁卫*.DNA表观遗传修饰的研究进展-基因组的第六碱基. 生理科学进展. 2012,43（3）:164-170.核心期刊
18. 张轶博，曾瑞霞，牛静，郑少鹏，贾弘禔，丁卫*.利用重组人α乳清蛋白和油酸大量快速制备高活性的HAMLET肿瘤杀伤复合物. 首都医科大学学报. 2012,33（5）:557-564.核心期刊
19. Jia J, Yu Y, Deng JH, Robinson N, Bovey M, Cui YH, Liu HR, Ding W*, Wu HG*, Wang XM*..A review of Omics research in acupuncture: the relevance and future prospects for understanding the nature of meridians and acupoints.. J Ethnopharmacol. . 2012,140（3）:594-603.SCI
20. 张晨光#,丁卫*.G 蛋白偶联受体: 药物发现的摇篮. 首都医科大学学报. 2012,33(5):395-399.核心期刊
21. Zhang FL, Jia SQ, Zheng SP, Ding W*.Celastrol enhances AAV1-mediated gene expression in mice adipose tissues. Gene Therapy. 2011,2(18):128-134.SCI
22. 闫韶飞, 文朝阳, 高尔静, 牛静, 郑少鹏, 丁卫*.晚期内体的分选转运参与II型腺相关病毒在IB3人支气管上皮转化细胞中的转导激活过程. 首都医科大学学报. 2011,32(4):519-524.核心期刊
23. Jin RH, Sun Y, Qi XD, Zhang HH, Zhang YL, Li N, Ding W*, Chen DX*.E2F1 is Involved in DNA Single-strand Break Repair through Cell-cycle-dependent Upregulation of XRCC1 Expression . DNA Repair. 2011,10(9):926-933.SCI
24. 路钊，郑少鹏，牛静，贾弘禔，丁卫*.BATF2/SARI通过抑制p53依赖的NFκB转录活性诱导肿瘤细胞凋亡. 中国生物化学与分子生物学报. 2011,27(6):524-532.核心期刊
25. Ren X, Zhang T, Hu J, Ding W, Wang X*.Triptolide T10 enhances AAV-mediated gene transfer in mice striatum. Neurosci Lett.. 2010,479(3) :187-91.SCI
26. 张凤兰, 文朝阳, 丁卫*.腺相关病毒基因治疗载体的改良与应用. 首都医科大学学报. 2009,30(4):565-573.核心期刊
27. Zhang T, Hu J, Ding W, Wang X*.Doxorubicin augments rAAV-2 transduction in rat neuronal cells. Neurochem Int. 2009,55(7):521-8.SCI
28. 油红捷, 闫韶飞, 丁卫*.脂肪因子visfatin的调节与功能多样性. 生物化学与生物物理进展. 2008,35(12):1351-1357.SCI
29. 贾书勤, 张凤兰, 丁卫*.红外荧光素Alexa Fluor 647标记的2型腺相关病毒保持天然的感染活性. 中国生物化学与分子生物学报. 2008,24(12):1152-1157.核心期刊
30. Ding W, Zhang NL, Engelhardt JF*.Dose-Dependent Trafficking of rAAV2 through both Late and Recycling Endosomes. Molecular Therapy. 2006,13(4):671-82.SCI
31. Ding W, Zhang L, Yan Z, Engelhardt JF*.Intracellular trafficking of adeno-associated viral vectors. Gene Therapy. 2005,12(11):873-80.SCI
32. Ding W, Yan Z, Zak R, Saavedra M, Rodman DM, Engelhardt JF*.Second-strand genome conversion of adeno-associated virus type 2 (AAV-2) and AAV-5 is not rate limiting following apical infection of polarized human airway epithelia. J Virology. 2003,77(13): 7361-6.SCI
33. Ding W, Fujita H, Kawai M*.The length of cooperative units on the thin filament in rabbit psoas muscle fibres. Experimental Physiology. 2002,87（6）:691-7.SCI
主编或副主编的著作/译著
1. 《Medical Genetics(英文)》,主编,高等教育出版社,201404
2. 《遗传学工作者的生物信息学》,主译,科学出版社,200910
重要奖项