姓名：孙英 性别：男 职称：教授 招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：免疫学(博) 免疫学(硕) 研究方向名称：过敏和临床免疫学 电子信箱：ying.sun@ccmu.edu.cn


社会任职
1. Fellow of Academy of Life Sciences for Chinese in the UK
2. Council Member of Specialty Committee of Gerontology of World Federation of Chinese Medicine Societies
3. Member of American Academy of Asthma, Allergy and Immunology
4. Member of British Society for Allergy and Clinical Immunology
5. 中国免疫学会理事
6. 北京免疫学会理事
个人简历
1. 197703-198001:吉林医学院 本科学习
2. 198001-198504:吉林医学院微生物与免疫学系 任职
3. 198505-198909:北京大学医学部 硕士学习、任职
4. 198901-200203:英国伦敦大学，伦敦帝国学院医学院，国家心肺研究所 博士学习、任职
5. 200204-200303:台湾太景生物科技有限公司 任职
6. 200304-:伦敦国王学院 任职
7. 201410-:首都医科大学 任职
重要学术论文
1. Li Y, Chen S, Chi Y, Yang Y, Chen X, Wang H, Lv Z, Wang J, Yuan L, Huang P, Huang K, Corrigan CJ, Wang W*, Ying S*.Kinetics of accumulation of group 2 innate lymphoid cells in IL-33 and IL-25 induced murine models of asthma: potential role of the chemokine CXCL16. Cell Mol Immunol. 2019,16(1):86-97.SCI
2. Li Q, Hu Y, Chen Y, Lv Z, Wang J, An G, Du X, Wang H, Corrigan CJ, Wang W, Ying S*.IL-33 induces production of autoantibody against autologous respiratory epithelial cells: a potential mechanism for the pathogenesis of COPD. Immunology. 2019,157(2):137-150.SCI
3. Wang W, Li Y, Lv Z, Chen Y, Li Y, Huang K, Corrigan CJ, Ying S*.Bronchial Allergen Challenge of Patients with Atopic Asthma Triggers an Alarmin (IL-33, TSLP, and IL-25) Response in the Airways Epithelium and Submucosa. J Immunol. 2018,201(8):2221-2231.SCI
4. Huang P, Li Y, Lv Z, Wang J, Zhang Q, Yao X, Corrigan CJ, Huang K, Wang W, Ying S*.Comprehensive attenuation of IL-25-induced airway hyperresponsiveness, inflammation and remodelling by the PI3K inhibitor LY294002. Respirology. 2017,22(1):78-85.SCI
5. Shan S, Li Y, Wang J, Lv Z, Yi D, Huang Q, Corrigan CJ, Wang W, Quangeng Z, Ying S*.Nasal administration of interleukin-33 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma surrogate. Immunology. 2016,148(1):83-91.SCI
6. Lam EPS, Kariyawasam HH, Rana BMJ, Durham SR, McKenzie ANJ, Powell N, Orban N, Lennartz-Walker M, Hopkins C, Ying S, Rimmer J, Lund VJ, Cousins DJ, and Till SJ.IL-25/IL-33 responsive Th2 cells characterize nasal 1 polyps with default Th17 signature in nasal mucosa. J Allergy Clin Immunol. 2016,137(5):1514-1524.SCI
7. Yao X, Sun Y, Wang Wei, Sun Y.Interleukin (IL)-25: Pleiotropic roles in asthma. Respirology. 2016,21(4):638-647.SCI
8. Samitas K, Poulos N, Semitekolou M, Morianos I, Tousa S, Economidou E, Robinson DS, Kariyawasam HH, Zervas E, Corrigan CJ, Ying S, Xanthou G, Gaga M.Activin-A is overexpressed in severe asthma and is implicated in angiogenic processes.. Eur Respir J. 2016,47(3):769-782.SCI
9. Pillai P, Chan YC, Wu SY, Ohm-Laursen L, Thomas C, Durham SR, Menzies-Gow A, Rajakulasingam RK, Ying S, Gould HJ, Corrigan CJ.Omalizumab reduces bronchial mucosal IgE and improves lung function in non-atopic asthma. Eur Respir J. 2016,48(6):1593-1601.SCI
10. Fang CL, Yin LJ, Sharma S, Kierstein S, Wu HF, Eid G, Haczku A, Corrigan CJ, Ying S*.Resistin-like molecule-β (RELM-β) targets airways fibroblasts to effect remodelling in asthma: from mouse to man. Clin Exp Allergy. 2015,45(5):940-952.SCI
11. Li Y, Wang W*, Huang P, Zhang Q, Yao X, Wang J, Lv Z, An Y, Corrigan CJ, Huang K*, Ying S.Distinct sustained structural and functional effects of IL-33 and IL-25 on the airways in a murine asthma surrogate. Immunology. 2015,145(4):508-518.SCI
12. Yao X, Wang W*, Li Y, Huang P, Zhang Q, Wang J, Wang W, Lv Z, An Y, Qin J, Corrigan CJ, Huang K, Sun Y, Ying S. IL-25 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma model. Respiratory Research. 2015,16(1):39.SCI
13. Kay AB, Ying S, Ardelean E, Mlynek A, Kita H, Clark P, Maurer M.Elevations in vascular markers and eosinophils in chronic spontaneous urticarial weals with low-level persistence in uninvolved skin. Br J Dermatol. 2014,171(3):505-511.SCI
14. Pillai P, Fang C, Chan YC, Shamji MH, Harper C, Wu SY, Ohm-Laursen L, Durham SR, Menzies-Gow A, Rajakulasingam RK, Ying S, Corrigan CJ, Gould HJ.Allergen-specific IgE is not detectable in the bronchial mucosa of nonatopic asthmatic patients. J Allergy Clin Immunol . 2014,133(6):1770-1772.SCI
15. Kay AB, Ying S, Ardelean E, Mlynek A, Kita H, Clark P, Maurer M.Calcitonin gene-related peptide and vascular endothelial growth factor are expressed in lesional but not uninvolved skin in chronic spontaneous urticaria. Clin Exp Allergy. 2014,44(8):1053-1060.SCI
16. Chan YC, Ramadani F, Santos AF, Pillai P, Ohm-Laursen L, Harper CE, Fang C, Dodev TS, Wu SY, Ying S, Corrigan CJ, Gould HJ."Auto-anti-IgE": naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation. J Allergy Clin Immunol . 2014,134(6):1394-1401.SCI
17. Kay AB, Clark P, Maurer M, Ying S.Elevations in T-helper-2-initiating cytokines (interleukin-33, interleukin-25 and thymic stromal lymphopoietin) in lesional skin from chronic spontaneous ('idiopathic') urticaria. Br J Dermatol. 2014,172(5):1294-1302.SCI
18. XJ Yao, KW Huang, Y Li, Q Zhang, JJ Wang, W Wang, J Liu , Z Lv, YQ An, YZ Ding, C J Corrigan, W Wang*, YC Sun*, Ying S*.Direct comparison of the dynamics of IL-25- and “allergen”-induced airways inflammation, remodelling and hypersensitivity in a murine asthma model. Clin Exp Allergy. 2014,44(5):765-777.SCI
19. Corrigan CJ, Napoli RL, Meng Q, Fang C, Wu H, Tochiki K, Reay V, Lee TH, Ying S*.Reduced expression of the prostaglandin E2 receptor E-prostanoid 2 on bronchial mucosal leukocytes in patients with aspirin-sensitive asthma. J Allergy Clin Immunol . 2012,129(6):1636-1646.SCI
20. Fang C, Meng Q, Wu H, Eid G, Zhang G, Zhang X, Yang S, Huang K, Lee TH, Corrigan CJ, Ying S*.Resistin-like molecule-β is a human airway remodelling mediator. Eur Respir J. 2012,39(2)::458-466.SCI
21. Wang W, Fan YQ, Lv Z, Yao XJ, Wang W, Huang KW, Meng Q, Fang CL, Lee TH, Corrigan CJ, An YQ, Ying S*.Interleukin-25 promotes basic fibroblast growth factor expression by human endothelial cells through interaction with IL-17RB, but not IL-17RA. Clin Exp Allergy. 2012,42(11):1604-1614.SCI
22. Corrigan CJ, Wang W, Meng Q, Fang C, Wu H, Reay V, Lv Z, Fan YQ, An YQ, Wang YH, Liu YJ, Lee TH, Ying S*.T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma. Proc Natl Acad Sci U S A. 2011,108(4):1579-1584.SCI
23. Corrigan CJ, Wang W, Meng Q, Fang C, Eid G, Caballero MR, Lv Z, An Y, Wang YH, Liu YJ, Kay AB, Lee TH, Ying S*.Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses. J Allergy Clin Immunol. 2011,128(1):116-124 .SCI
24. Fang C, Siew LQ, Corrigan CJ, Ying S*.The role of thymic stromal lymphopoietin in allergic inflammation and chronic obstructive pulmonary disease. Arch Immunol Ther Exp (Warsz). 2010,58(2):81-90.SCI
25. Corrigan CJ, Jayaratnam A, Wang YH, Liu YJ, de Waal Malefyt R, Meng Q, Kay AB, Phipps S, Lee TH, and Ying S*.Early production of thymic stromal lymphopoietin precedes infiltration of dendritic cells expressing its receptor in allergen-induced late phase cutaneous responses in atopic subjects. Allergy. 2009,64(7):1014-1022.SCI
26. Ying S*, O’Connor B, Ratoff J, Meng Q, Fang CL, Cousins D, Zhang G, Gu S, Gao Z, Shamji B, Edwards MJ, Lee TH, and Corrigan CJ.Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease. J Immunol. 2008,181(4):2790-2798.SCI
27. Ying S*, Meng Q, Scadding G, Parikh A, Corrigan CJ, Lee TH .Aspirin sensitive rhinosinusitis is associated with reduced E-prostanoid 2 (EP2) receptor expression on nasal mucosal inflammatory cells . J Allergy Clin Immunol. 2006,117(2):312-318.SCI
28. Ying S, Meng Q, Corrigan CJ, Lee TH .Lack of filaggrin expression in the human bronchial mucosa . J Allergy Clin Immunol. 2006,118(6):1386-1388.SCI
29. Ying S*, O’Connor B, Ratoff J, Meng Q, Mallett K, Cousins D, Robinson D, Zhang GZ, Zhao JS, Lee TH, Corrigan CJ.Thymic stromal lymphopoietin (TSLP) expression is increased in asthmatic airways correlates with expression of Th2-attracting chemokines and disease severity . J Immunol. 2005,174(12):8183-8190.SCI
30. Ying S*, O’Connor B, Meng Q, Woodman N, Greenaway S, Wong H, Mallett K, Lee TH, Corrigan CJ .Expression of prostaglandin E2 receptor subtypes on cells in sputum from asthmatics and controls: effect of allergen inhalational challenge. J Allergy Clin Immunol. 2004,114(6):1309-1316.SCI
31. Ying S, Khan LN, Meng Q, C Bames NC, Kay AB .Cyclosporin A, apoptosis of BAL T-cells and expression of Bcl-2 in asthmatics . Eur Respir J. 2003,22(2):207-212.SCI
32. Ying S, Meng Q, Kay AB, Robinson DS.Elevated expression of IL-9 mRNA in the bronchial mucosa of atopic asthmatics: relationships to eosinophils, mast cells and T lymphocytes. Clin Exp Allergy. 2002,32(6) :866-871.SCI
33. Ying S*, Yoko Kikuchi, Meng Q, Kay AB, Kaplan AP .Th1/Th2 cytokines and inflammatory cells in skin biopsies from chronic idiopathic urticaria: comparison with the allergen-induced late-phase cutaneous reaction. J Allergy Clin Immunol . 2002,109(4):694-700.SCI
34. Ying S, Humbert M, Meng Q, Pfister R, Menz G, Could HJ, Kay AB, Durham SR.Local expression of germ-line gene transcripts and RNA for the heavy chain of IgE in the bronchial mucosa in atopic and non-atopic asthma. J Allergy Clin Immunol. 2001,107(4):686-692.SCI
35. Ying S, Meng Q, Barata LT, and Kay AB.Macrophage inflammatory protein-1 (MIP-1) and CCR-1 in allergen-induced skin late phase reactions (LPR): relationship to macrophages, neutrophils, basophils, eosinophils and T lymphocytes. Clin Exp Allergy . 2001,31(11):1724-1731.SCI
36. Ying S, Robinson DS, Meng Q, Barata LT, McEuen AR, Buckley MG, Walls AF, Askenase PW, Kay AB.C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 24-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines. J Immunol. 1999,163(7) :3976-3984.SCI
37. Ying S, Meng Q, Zeibecoglou K, Robinson DS, Macfarlane A, Humbert M, Kay AB.Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (Intrinsic) asthmatics. J Immunol. 1999,163(11）:6321-6329.SCI
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