姓名：赵非 性别：男 职称：研究员、教授 招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：病原生物学(博) 病原生物学(硕) 研究方向名称：病毒载体的研发、生产与应用 电子信箱：zhaofei@ccmu.edu.cn


社会任职
个人简历
1. 199709-200106:华中农业大学 本科
2. 200109-200406:中国科学院武汉病毒研究所 硕士
3. 200409-200906:德国汉诺威医学院 博士
4. 200907-201004:德国汉诺威医学院 博士后
5. 201005-201206:美国国立卫生研究院 博士后
6. 201207-201812:中国科学院武汉病毒研究所 副研究员
7. 201812-:北京脑科学与类脑研究中心 载体工程中心主任
8. 202001-:首都医科大学 研究员
重要学术论文
1. Wang H, Chen J, Xu X, Sun WJ, Chen X, Zhao F, Luo MH, Liu C, Guo Y, Xie W, Zhong H, Bai T, Tian Y, Mao Y, Ye C, Tao W, Li J, Farzinpour Z, Li J, Zhou JN, Wang K, He J, Chen L, Zhang Z. Direct auditory cortical input to the lateral periaqueductal gray controls sound-driven defensive behavior. PLoS Biol. 2019,17(8):e**.SCI
2. Sun T, Song Z, Tian Y, Tian W, Zhu C, Ji G, Luo Y, Chen S, Wang L, Mao Y, Xie W, Zhong H, Zhao F, Luo MH, Tao W, Wang H, Li J, Li J, Zhou J, Wang K, Zhang Z. Basolateral amygdala input to the medial prefrontal cortex controls obsessive-compulsive disorder-like checking behavior. Proc Natl Acad Sci U S A. 2019,116(9):3799-3804.SCI
3. Dong SW, Jiao LS, Yang M, Duan YL, Chen YB, Zhao F, Zhang AM, Liu L, Luo MH, Xia XS. The Susceptibility of Primary Dermis Fibroblasts from the Chinese Tree Shrew to Human Cytomegalovirus Infection. Virol Sin. 2019,34(3):270-277.SCI
4. Zhang MX, Cai Z, Zhang M, Wang XM, Wang Y, Zhao F, Zhou J, Luo MH, Zhu Q, Xu Z, Zeng WB, Zhong B, Lin D. USP20 Promotes Cellular Antiviral Responses via Deconjugating K48-Linked Ubiquitination of MITA. J Immunol. 2019,202(8):2397-2406.SCI
5. Zhu X, Zhou W, Jin Y, Tang H, Cao P, Mao Y, Xie W, Zhang X, Zhao F, Luo MH, Wang H, Li J, Tao W, Farzinpour Z, Wang L, Li X, Li J, Tang ZQ, Zhou C, Pan ZZ, Zhang Z. A Central Amygdala Input to the Parafascicular Nucleus Controls Comorbid Pain in Depression. Cell Rep. 2019,29(12):3847-3858.SCI
6. Wang YY, Wang Y, Jiang HF, Liu JH, Jia J, Wang K, Zhao F, Luo MH, Luo MM, Wang XM. Impaired glutamatergic projection from the motor cortex to the subthalamic nucleus in 6-hydroxydopamine-lesioned hemi-parkinsonian rats. Exp Neurol. 2018,300:135-148.SCI
7. Wen L, Qiu Y, Cheng S, Jiang X, Ma YP, Fang W, Wang W, Cui J, Ruan Q, Zhao F, Hu F, Luo MH. Serologic and viral genome prevalence of HSV, EBV, and HCMV among healthy adults in Wuhan, China. J Med Virol. 2018,90(3):571-581.SCI
8. Tian Y, Yang C, Cui Y, Su F, Wang Y, Wang Y, Yuan P, Shang S, Li H, Zhao J, Zhu D, Tang S, Cao P, Liu Y, Wang X, Wang L, Zeng W, Jiang H, Zhao F, Luo M, Xiong W, Qiu Z, Li XY, Zhang C. An Excitatory Neural Assembly Encodes Short-Term Memory in the Prefrontal Cortex. Cell Rep. 2018,22(7):1734-1744.SCI
9. Zhao F, Jiang HF, Zeng WB, Shu Y, Luo MH, Duan S. Anterograde Trans-Synaptic Tagging Mediated by Adeno-Associated Virus. Neurosci Bull. 2017,33(3):348-350.SCI
10. Yu K, Ahrens S, Zhang X, Schiff H, Ramakrishnan C, Fenno L, Deisseroth K, Zhao F, Luo MH, Gong L, He M, Zhou P, Paninski L, Li B. The central amygdala controls learning in the lateral amygdala. Nat Neurosci. 2017,20(12):1680-1685.SCI
11. Liu XJ, Jiang X, Huang SN, Sun JY, Zhao F, Zeng WB, Luo MH. Human cytomegalovirus infection dysregulates neural progenitor cell fate by disrupting Hes1 rhythm and down-regulating its expression. Virol Sin. 2017,32(3):188-198.SCI
12. Jiang HF, Wang W, Jiang X, Zeng WB, Shen ZZ, Song YG, Yang H, Liu XJ, Dong X, Zhou J, Sun JY, Yu FL, Guo L, Cheng T, Rayner S, Zhao F, Zhu H, Luo MH. ORF7 of Varicella-Zoster Virus Is Required for Viral Cytoplasmic Envelopment in Differentiated Neuronal Cells. J Virol. 2017,91(12): pii.SCI
13. Cheng S, Jiang X, Yang B, Wen L, Zhao F, Zeng WB, Liu XJ, Dong X, Sun JY, Ming YZ, Zhu H, Rayner S, Tang Q, Fortunato E, Luo MH. Infected T98G glioblastoma cells support human cytomegalovirus reactivation from latency. Virology. 2017,510:205-215.SCI
14. Qiao GH, Zhao F, Cheng S, Luo MH. Multipotent mesenchymal stromal cells are fully permissive for human cytomegalovirus infection. Virol Sin. 2016,31(3):219-28.SCI
15. Li XJ, Liu XJ, Yang B, Fu YR, Zhao F, Shen ZZ, Miao LF, Rayner S, Chavanas S, Zhu H, Britt WJ, Tang Q, McVoy MA, Luo MH. Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neural Progenitor Cells. J Virol. 2015,89(13):6792-804.SCI
16. Zhou M, Huang Y, Cheng Z, Zhao F, Li J, Zhi X, Tian X, Sun W, Hu K. Revival, characterization, and hepatitis B virus infection of cryopreserved human fetal hepatocytes. J Virol Methods. 2014,207:29-37.SCI
17. Zhou M, Zhao F, Li J, Cheng Z, Tian X, Zhi X, Huang Y, Hu K. Long-term maintenance of human fetal hepatocytes and prolonged susceptibility to HBV infection by co-culture with non-parenchymal cells. J Virol Methods. 2014,195:185-93.SCI
18. Feng H, Chen P, Zhao F, Nassal M, Hu K. Evidence for multiple distinct interactions between hepatitis B virus P protein and its cognate RNA encapsidation signal during initiation of reverse transcription. PLoS One. 2013,8(8):e72798.SCI
19. Kapanadze T, Gamrekelashvili J, Ma C, Chan C, Zhao F, Hewitt S, Zender L, Kapoor V, Felsher DW, Manns MP, Korangy F, Greten TF. Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma. J Hepatol. 2013,59(5):1007-13.SCI
20. Duffy A, Zhao F, Haile L, Gamrekelashvili J, Fioravanti S, Ma C, Kapanadze T, Compton K, Figg WD, Greten TF. Comparative analysis of monocytic and granulocytic myeloid-derived suppressor cell subsets in patients with gastrointestinal malignancies. Cancer Immunol Immunother. 2013,62(2):299-307.SCI
21. Wang W, Peng H, Li J, Zhao X, Zhao F, Hu K. Controllable inhibition of hepatitis B virus replication by a DR1-targeting short hairpin RNA (shRNA) expressed from a DOX-inducible lentiviral vector. Virus Genes. 2013,46(3):393-403.SCI
22. Tian X, Zhao F, Cheng Z, Zhou M, Zhi X, Li J, Hu K. GCN5 acetyltransferase inhibits PGC1α-induced hepatitis B virus biosynthesis. Virol Sin. 2013,28(4):216-22.SCI
23. Chen P, Gan Y, Han N, Fang W, Li J, Zhao F, Hu K, Rayner S. Computational evolutionary analysis of the overlapped surface (S) and polymerase (P) region in hepatitis B virus indicates the spacer domain in P is crucial for survival. PLoS One. 2013,8(4):e60098.SCI
24. Zhao F, Hoechst B, Gamrekelashvili J, Ormandy LA, Voigtl?nder T, Wedemeyer H, Ylaya K, Wang XW, Hewitt SM, Manns MP, Korangy F, Greten TF. Human CCR4+ CCR6+ Th17 cells suppress autologous CD8+ T cell responses. J Immunol. 2012,188(12):6055-62.SCI
25. Zhao F, Korangy F, Greten TF. Cellular immune suppressor mechanisms in patients with hepatocellular carcinoma. Dig Dis. 2012,30(5):477-82.SCI
26. Greten TF, Zhao F, Gamrekelashvili J, Korangy F.Human Th17 cells in patients with cancer: Friends or foe?. Oncoimmunology. 2012,1(8):1438-1439.SCI
27. Zhao F, Hoechst B, Duffy A, Gamrekelashvili J, Fioravanti S, Manns MP, Greten TF, Korangy F. S100A9 a new marker for monocytic human myeloid-derived suppressor cells. Immunology. 2012,136(2):176-83.SCI
28. Hoechst B, Voigtlaender T, Ormandy L, Gamrekelashvili J, Zhao F, Wedemeyer H, Lehner F, Manns MP, Greten TF, Korangy F. Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor. Hepatology. 2009,50(3):799-807.SCI
29. Zhao F, Obermann S, von Wasielewski R, Haile L, Manns MP, Korangy F, Greten TF. Increase in frequency of myeloid-derived suppressor cells in mice with spontaneous pancreatic carcinoma. Immunology. 2009,128(1):141-9.SCI
30. Zhao F, Vermeer B, Lehmann U, Kreipe H, Manns MP, Korangy F, Greten TF. Identification of a novel murine pancreatic tumour antigen, which elicits antibody responses in patients with pancreatic carcinoma. Immunology. 2009,128(1):134-40.SCI
31. Zhen D, Liu H, Wang SJ, Zhang JJ, Zhao F, Zhou NY. Plasmid-mediated degradation of 4-chloronitrobenzene by newly isolated Pseudomonas putida strain ZWL73. Appl Microbiol Biotechnol. 2006,72(4):797-803.SCI
主编或副主编的著作/译著
重要奖项