姓名：李良 性别：女 职称：教授 招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：病理学(博) 病理学(硕) 研究方向名称：缺血缺氧性脑病 电子信箱：liliang@ccmu.edu.cn


社会任职
1. 北京神经内科学会基础与转化医学专业委员会（BNA-BTA）常务委员
2. 中国老年学学会老年医学委员会认知障碍专家委员会常务委员
3. 北京医学会病理学分会第九届委员会委员
4. 中国药理学会抗衰老与老年痴呆专业委员会委员
5. 中华医学会病理学分会神经学组委员
个人简历
1. 198409-198907:首都医科大学 本科
2. 198908-:首都医科大学病理系 教师
3. 199609-199907:首都医科大学 硕士
4. 200101-200201:美国纽约州立基础研究所 访问
5. 200209-200507:首都医科大学 博士
重要学术论文
1. Cao D, Cui J, Cao D, Guo C, Min G, Liu M, Li L*..S-adenosylmethionine reduces the inhibitory effect of Aβ on BDNF expression through decreasing methylation level of BDNF exon Ⅳ in rats. Biochem Biophys Res Commun.. 2018,495:2609-2615.SCI
2. Han CL, Ge M, Liu YP, Zhao XM, Wang KL, Chen N, Hu W, Zhang JG, Li L*, Meng FG*.Long non-coding RNA H19 contributes to apoptosis of hippocampal neurons by Inhibiting let-7b in a rat model of temporal lobe epilepsy. Cell Death Dis.. 2018,23；9（6）:617.SCI
3. Li Q, Cui J, Fang C, Liu M, Min G, Li L*.S-adenosylmethionine attenuates oxidative stress and neuroinflammation induced by Amyloid-β through modulation of glutathione metabolism. J Alzheimer's Dis. 2017,58:549-558.SCI
4. Zhang XW， Huang X，Fang C，Li Q，Cui J, Sun J, Li L*.miR-124 regulates the expression of BACE1 in the hippocampus under chronic cerebral hypoperfusion. . Mol neurobiol.. 2017,54(4):2498-2506..SCI
5. Fang C, Li Q, Min G, Liu M, Cui J, Sun J, Li L*.MicroRNA-181c Ameliorates Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats. Mol Neurobiol.. 2017,54(10):8370-8385.SCI
6. Qian Li, Jing Cui, Chen Fang, Xiaowen Zhang, Liang Li* .S-adenosylmethionine administration attenuates low brain-derived neurotrophic factor expression induced by chronic cerebrovascular hypoperfusion or beta amyloid treatment.. Neurosci Bull. 2016,32(2):153-161.SCI
7. Qinglin Yang, XiangmeiWu, Jing Sun, Jing Cui, Liang Li*.Epigenetic Features Induced by Ischemia-Hypoxia in Cultured Rat Astrocytes. Molecular neurobiology. 2016,53(1):436-445.SCI
8. Xiangmei Wu, Jing Sun, Xiaowen Zhang, Xiaona Li, Zichen Liu, Liang Li*.Epigenetic signature of chronic cerebral hypoperfusion and beneficial effects of S-adenosylmethionine in rats. Molecular neurobiology. 2014,50(3):839-851.SCI
9. Xinling Gu, Jing Sun, Shen Li, Xiangmei Wu, Liang Li* .Oxidative stress induces DNA demethylation and histone acetylation in SH-SY5Y cells: potential epigenetic mechanisms in gene transcription in Aβ production . Neurobiology of Aging . 2013,34(4):1069-1079.SCI
10. Hong Liu, Anfeng Xing, Xiaojuan Wang, Guozhen Liu, Liang Li* .Regulation of β-amyloid level in the brain of rats with cerebrovascular hypoperfusion. Neurobiology of Aging . 2012,33(4):826:e31-42 .SCI
11. Xuewen Guo, Xiangmei Wu, Lerong Ren, Guozhen Liu, Liang Li* .Epigenetic mechanisms of Aβ production in anisomycin-treated SH-SY5Y cells . Neuroscience. 2011,194:271-281.SCI
12. Xiaojuan Wang, Hong Liu，Liang Li*.Effects of chronic cerebrovascular hypoperfusion of beta- and gamma-secretase on learning and memory in rats . Neural Regeneration Research（NRR）. 2010,5(5):353-357.SCI
13. Xiaojuan Wang, Anfeng Xing, Changlei Xu, Qing Cai, Hong Liu, Liang Li* .Cerebrovascular hypoperfusion induces spatial memory impairment, synaptic changes and Aβ oligomerization in rats . J Alzheimer’s Disease. 2010,21(3):813-822.SCI
14. Liang Li, Yujin Su, Chunli Zhao, Qunyuan Xu . Role of Nurr1 and Ret in inducing rat embryonic neural precursors to dopaminergic neurons . Neurological Res. . 2009,31（5）:534-540 .SCI
15. Ye DING , Liang LI*.Lipopolysaccharide preconditioning induces protection against lipopolysaccharide-induced neurotoxicity in organotypic midbrain slice culture . Neurosci Bull. 2008,24(4):209-218 .SCI
16. Liang Li, Yujin Su, Chunli Zhao, Huanying Zhao, Guozhen liu, Jue Wang, Qunyuan Xu*.The role of Ret receptor tyrosine kinase in dopaminergic neuron development . Neuroscience . 2006,142(2):391-400.SCI
17. Liang Li, Amitabha Sengupta, Niloufar Haque, Inge Grundke- Iqbal, Khalid Iqbal*.Memantine Inhibits and Reverses the Alzheimer Type Abnormal Hyperphosphorylation of Tau and Associated Neurodegeneration . FEBS Lett 2004(566):261-9 . 2004,566:261-269.SCI
18. C-X Gong, F Liu, G-X Wu, Sanda Rossie, Jerzy Wegiel, Liang Li, Inge Grundke-Iqbal, Khalid Iqbal*.Dephosphorylation of microtubule-associated protein tau by protein phosphatase 5. J Neurochemistry . 2004,88:298-310.SCI
主编或副主编的著作/译著
1. 《Pathology》,主编,高等教育出版社,201509
2. 《Guide book for laboratory of abnormal human morphology》,主编,高等教育出版社,201201
3. 《临床病理学》,副主编,科学出版社 ,201007
4. 《病理学彩色图谱》,副主编,科学出版社,200604
重要奖项