姓名：罗大力 性别：女 职称：教授 招生院所：基础医学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：药理学(博) 药理学(硕) 研究方向名称：心血管系统药理学和细胞内钙信号转导 电子信箱：luodl@ccmu.edu.cn


社会任职
个人简历
1. 199110-199210:日本新泻大学医学部药理系 学习
2. 199709-200110:哈尔滨医科大学药理室 教授及系副主任
3. 199809-200106:哈尔滨医科大学生理系 博士
4. 199905-200005:美国国家卫生科学院(NIH) 学习及研究(博士培养)
5. 200110-200309:北京大学第三临床学院心血管研究所 博士后
6. 200309-200510:北京大学心血管研究所 研究员
7. 200406-200412:美国国家卫生科学院(NIH) 合作研究
8. 200511-:首都医科大学基础医学院药理系 教授
重要学术论文
1. Xue J#, Yan X#, Yang Y#, Chen M, Wu L, Gou Z, Sun Z, Talabieke S, Zheng Y, Luo D*.Connexin 43 dephosphorylation contributes to arrhythmias and cardiomyocyte apoptosis in ischemia/reperfusion hearts. Basic Res Cardiol. 2019,114(5):40. :40-47.SCI
2. Yang Y#, Yan X#, Xue J, Zheng Y, Chen M, Sun Z, Liu T, Wang C, You H, Luo D*.Connexin43 dephosphorylation at serine 282 is associated with connexin43-mediated cardiomyocyte apoptosis. Cell Death Differ. 2019,513(3):567-572..
3. Li S#, Xue J#, Sun Z, Liu T, Zhang Z, Wang L, You H, Fan Z, Zheng Y, Luo D*.CaMKII potentiates store-operated Ca2+ entry through enhancing STIM1 aggregation and interaction with Orai1. Cell Physiol Biochem. 2018,46:1042-1054.SCI
4. Wang H, Wang C, Wang L, Liu T, Wang Z, You H, Zheng Y, Luo D*.Orai1 downregulation impairs lymphocyte function in type 2 diabetes mellitus. Biochem Biophy Res Commun. 2018,500:384-390.SCI
5. Liu T#, Wang Z#, Chen X, You H, Xue J, Cai D, Zheny Y, Xu Y, Luo D*..Low molecular weight fucoidan protects against hindlimb ischemic injury in type 2 diabetic mice through enhancing endothelial nitric oxide synthase phosphorylation . J Diabetes . 2018,doi: 10.1111/1753-0407.12667:1-15.SCI
6. Zheng Y, Liu T, Wang Z, Xu Y, Zhang Q, Luo D*.Low molecular weight fucoidan attenuates liver injury via SIRT1/AMPK/PGC1α axis in db/db mice.. Int J Biol Macromol. 2018,112:929-936.SCI
7. Wang Z, Liu T, Chen X, You H, Zhang Q, Xue J, Zheny Y, Luo D*.Low molecular weight fucoidan ameliorates hindlimb ischemic injury in type 2 diabetic rats. J Ethnopharmacol. 2017,210:434-442.SCI
8. Liang Z, Zheng Y, Wang J, Zhang Q, Ren S, Liu T, Wang Z, Luo D*.Low molecular weight fucoidan ameliorates streptozotocin-induced hyper-responsiveness of aortic smooth muscles in type1 diabetes rats. J Ethnopharmacol. 2016,191:341–349.SCI
9. Chen M, hengy Y, #, Song Y, Xue J, Liang Z, Yan X, Luo D*.Low-dose gadolinium chloride protects against myocardial ischemia/reperfusion injury in rats. Acta Pharmacologica Sinica. 2016,37:1-10.SCI
10. Zhang L, Wang L, Li S, Xue J, Luo D*.Calsequestrin-1 regulates store operated Ca2+ entry by inhibiting STIM1 aggregation. Cell Physiol Biochem. 2016,38:2183-2193.SCI
11. Yan X, Zeng Z, Chen M, Li C, Li S, Luo D*. Gap junction-associated Na+ influx is involved in the mediation of Ca2+ transients in neonatal rat ventricular myocytes. J Cardiovasc Pharmacol. 2015,66:41-49.SCI
12. Wang L, Li S, Zheng Y, Yan X, Chen M, Wang H, Zhang L, Putney JW* and Luo D*.Calsequestrin1 assumes a retrograde role in store-operated Ca2+ entry via regulation of STIM1-Orai1 interaction. Sci Rep. 2015,DOI: 10.1038/srep11349 :1-12.
13. Zheng Y, Zhang H, Yan X, Chen M, Qi T, Zhang L, Luo D.Protective effect of low dose gadolinium chloride against isoproterenol-induced myocardial injury in rat. Apoptosis. 2015,20（9）:1164-1175.SCI
14. Yu X, Zhang Q, Cui W, Zeng Z, Yang W, Zhang C, Zhao H, Gao W, Wang X and Luo D*.Low molecular weight fucoidan alleviates cardiac dysfunctionin diabetic Goto-Kakizaki rats by reducing oxidative stressand cardiomyocyte apoptosis. J Diabetes Res. 2014,http://dx.doi.org/10.1155/2014/420929:1-10.SCI
15. Zeng Z, Zhang H, Lin N, Kang M, Zheng Y, Li Chen, Xu P, Wu Y and Luo D*.Role of inositol-1,4,5-trisphosphate receptor in the regulation of clcium tansients in nonatal rat vntricular mocytes. J Pharmacol Sci. 2014,126:37–46.SCI
16. Kang M, Lin Na, Li Chen, Meng Q, Zheng Y, Yan X, Deng J, Ou Y, Zhang C, He J and Luo D*.Cx43 phosphorylation on S279/282 and intercellular communication are regulated by IP3/IP3 receptor signaling. Cell Communication and Signaling. 2014,15:58-68.SCI
17. Zheng Y, Wang L, Zhu Z, Yan X, Zhang L, Xu P, Luo D*.Altered platelet calsequestrin abundance, Na+/Ca2+ exchange and Ca2+ signaling responses with the progression of diabetes mellitus. Thromb Res. 2014,134:674-681.SCI
18. Zhu Z, Zhou H, Yu X, Chen L, Ren S, Luo D*.Potential regulatory role of calsequestrin in platelet Ca2+ homeostasis and its association with platelet hyperactivity in diabetes mellitus. J Thromb Haemost. 2013,10 :116–24.SCI
19. Yang W, Yu X, Zhang Q, Lu Q, Wang J, Cui W, Zheng Y, Wang X, Luo D*.Attenuation of streptozotocin-induced diabetic retinopathy with low molecular weight fucoidan via inhibition of vascular endothelial growth factor. Exp Eye Res. 2013,115:96-105.SCI
20. Chen L, Meng Q, Yu X, Li C, Zhang C, Cui C, Luo D*. Possible mechanisms underlying the biphasic regulatory effects of arachidonic acid on Ca2+ signaling in HEK293 cells. Cell Signal. 2012,24:1565-1572.SCI
21. Li C, Meng Q, Yu X, Jing X, Xu P, Luo D*.Regulatory Effect of connexin 43 on basal Ca2+ signaling in rat ventricular myocytes. PLoS ONE. 2012,7:361-365,.SCI
22. Lihong Chen, Qingli Meng, Xian Jing, Pingxiang Xu, Dali Luo*.A role for protein kinase C in the regulation of membrane fluidity and Ca2+ flux at theendoplasmic reticulum and plasma membranes of HEK293 and Jurkat cells. Cellular Signalling. 2011,23:497–505.SCI
23. Xian Jing, Lihong Chen, Shuang Ren, Dali Luo*.Rational method in the repetitive calcium oscillation measurement in wild type human epithelial kidney cells. Cytotechnology. 2011,63:81–88.SCI
24. Zhixiang Zhu, Quanbin Zhang, Lihong Chen, Shuang Ren, Pingxing Xu, Yu Tang, Dali Luo*.Higher specificity of the activity of low molecular weight fucoidan forthrombin-induced platelet aggregation. Thrombosis Research. 2010,125:419–426.SCI
主编或副主编的著作/译著
1. 《pharmacology》,主编,高教出版社,201507
重要奖项