Jing Wei——Lecturer
Nationality:
CHINA

Phone:


Email:
betty_wj@tju.edu.cn

Office:
Room A205, Building 24, Tianjin University

School:
School of Pharmaceutical Science and Technology

ResearcherID:
K-1108-2015

Group weblink








Education Experience
2001-2004 Master of Engineering Pattern Recognition and Intelligence System Tianjin University, CN
2004-2007 Doctor of Engineering Medicinal Chemistry Tianjin University CN

Professional Experience
2007-2015 lecturer Tanjin University , China
1995-2001 Physician Laboratorian of Center for Disease Control and Prevention, Hexi District, Tianjin

Research Area
Wei’s research addresses mechanisms of drug activity with associated drug design. Computational approaches (e.g., molecular docking, pharmacophore modeling, quantitative structure-activity relationship (QSAR), molecular dynamics) are used to identify and characterize putative ligand binding sites, elucidate binding mechanisms, and guide rational design of potentially new drugs.




Honors and Awards
魏静，四乙酰核糖和二乙酰阿昔洛韦合成的新工艺，天津市人民政府，科技进步奖，二等奖，2009。（赵康、陈维瑜、魏静、杜云飞、王松青、苏艳芳、张秀东、陈炎泉）
魏静，第十三届“挑战杯”天津市大学生课外学术科技作品竞赛优秀指导教师，天津市委员会、天津市科学技术委员会、天津市教育工作委员会等，2015。

Patents

Highlighted Publications
The comparison of BLyS-binding peptides from phage display library and computer-aided design on BLyS–TACI interaction. Int. Immunopharmacol. 2015, 24 (2) 219–223.
Computer-aided de novo ligand design and docking/molecular dynamics study of Vitamin D receptor agonists. J. Mol. Model., 2012, 18（1）: 203–212.
Docking and molecular dynamics study on the inhibitory activity of novel inhibitors on epidermal growth factor receptor (EGFR). Med Chem. 2011, 7(1):24-31.
Adevances in the study of A2B adenosine receptor antagonists. Anta Pharmaceutica Sinica，2008，43 (3): 241-246.

ResearcherID Publications
Year Title Author(s) Source Volume
2011 Docking and Molecular Dynamics Study on the Inhibitory Activity of Novel Inhibitors on Epidermal Growth Factor Receptor (EGFR) Liao, Qing-Hua; Gao, Qing-Zhi; Wei, Jing; et al. Medicinal Chemistry 7
2011 Docking and molecular dynamics study on the inhibitory activity of N, N-disubstituted-trifluoro-3-amino-2-propanols-based inhibitors of cholesteryl ester transfer protein Dong, Bo-Liang; Liao, Qing-Hua; Wei, Jing Journal of Molecular Modeling 17
2012 Some insights into the binding mechanism of Aurora B kinase gained by molecular dynamics simulation Xiong, Rui; Cai, Xiao-Mei; Wei, Jing; et al. Journal of Molecular Modeling 18
2012 Homology Modeling and Antagonist Binding Site Study of the Human Histamine H2 Receptor Zhang, Jing; Qi, Tao; Wei, Jing Medicinal Chemistry 8
2012 Computer-aided de novo ligand design and docking/molecular dynamics study of Vitamin D receptor agonists Shen, Xiu-Long; Takimoto-Kamimura, Midori; Wei, Jing; et al. Journal of Molecular Modeling 18
2012 Computational studies of the binding modes of CCR1 antagonists Liu, Yuan; Chen, Binhui; Wei, Jing Molecular Simulation 38
2015 The comparison of BLyS-binding peptides from phage display library and computer-aided design on BLyS-TACI interaction Zhao, Yacong; Hao, Xiafei; Feng, Jiannan; et al. International Immunopharmacology 24
2015 Molecular Mechanism of the Affinity Interactions Between BAFF and Its Peptides by Molecular Simulations Fu, Xuegang; Xuan, Liyan; Wang, Yuzhe; et al. Protein and Peptide Letters 22
2015 Molecular dynamics study on drug resistance mechanism of HCV NS3/4A protease inhibitor: BI201335 Fu, Jianjian; Wei, Jing Molecular Simulation 41
2016 Suppression of tumor cell proliferation by quinine via the inhibition of the tumor necrosis factor receptor-associated factor 6-AKT interaction Liu, Wenjuan; Qi, Yonghao; Liu, Lingyu; et al. Molecular Medicine Reports 14