一、教育经历
2009－2014：南开大学，生物化学与分子生物学系，博士
2005－2009：南开大学，生物科学专业，学士

二、研究方向
动脉粥样硬化病理机制研究；
脂代谢与肿瘤；
非酒精性脂肪肝发病机制和治疗策略.

三、近5年论文 (#：共同第一作者；*：通讯作者)
1.Hu W, Zhang W, Chen Y, Rana Y, Teng R, Duan Y, Liu Z, Zhao B, Foeckler J, Weiler H, Han J, Miao QR. 2015. Nogo-B receptor deficiency increases LXR? nuclear translocation and hepatic lipogenesis via AMPK?-dependent pathway. Cell Metabolism, in revision.
2.Yang X, Sun L, Li Y, Ma C, Yang J, Zhang W, Zhao B, Jia L, Duan Y, Han J, Li X, Chen Y*. 2015. NaoXinTong inhibits the advanced atherosclerosis and enhances the plaque stability in apoE deficient mice. Journal of Cardiovascular Pharmacology, accepted.
3.Yang X, Yao H, Chen Y, Sun L, Li Y, Ma X, Duan S, Li X, Xiang R, Han J, Duan Y*. 2015. Inhibition of glutathione production induces macrophage CD36 expression and enhances cellular oxLDL uptake. The Journal of Biological Chemistry. 2015;290:21788-99.
4.Liu M, Pan Q, Chen Y, Yang X, Zhao B, Jia L, Zhu Y, Zhang B, Gao X, Li X, Han J*, Duan Y*. Administration of Danhong Injection to diabetic db/db mice inhibits the development of diabetic retinopathy and nephropathy. Scientific Reports. 2015;5:11219.
5.Liu M, Chen Y, Zhang L, Wang Q, Ma X, Li X, Xiang R, Zhu Y, Qin S, Yu Y, Jiang X, Duan Y, Han J*. Regulation of hepatic cholesteryl ester transfer protein expression and reverse cholesterol transport by inhibition of DNA topoisomerase II. The Journal of Biological Chemistry 2015;290:14418-29.
6.Zhang W, Wang X, Hu W, Liu L, Li X, Han J, Chen Y*, Duan Y*. Co-treatment of pitavastatin and dexamethasone exacerbates the high fat diet-induced atherosclerosis in apoE-/- mice. Journal of Cardiovascular Pharmacology 2015;66:189-95.
7.Ma X, Liu Y, Wang Q, Chen Y, Liu M, Li X, Xiang R, Wei Y, Duan Y, Han J. Tamoxifen induces the development of hernia in mice by activating MMP-2 and MMP-13 expression. Biochimica et Biophysica Acta-Molecular Basis of Disease 2015;1852:1038-1048.
8.Chen Y#, Duan Y#, Yang X, Sun L, Liu M, Wang Q, Ma X, Zhang W, Li X, Hu W, Miao QR, Xiang R, Hajjar DP, Han J. Inhibition of ERK1/2 and activation of LXR synergistically reduce atherosclerotic lesions in apoE deficient mice. Arteriosclerosis Thrombosis and Vascular Biology 2015;35:948-959.
9.Liu M, Pan Q, Chen Y, Yang X, Zhao B, Jia L, Zhu Y, Han J, Li X, Duan Y. NaoXinTong inhibits the development of diabetic retinopathy in db/db mice. Evidence-Based Complementary and Alternative Medicine 2015;2015:242517.
10.Ma X, Wang Q, Liu Y, Chen Y, Zhang L, Jiang M, Li X, Xiang R, Miao RQ, Duan Y, Han J. Inhibition of tumor growth by U0126 is associated with induction of interferon-? production. International Journal of Cancer 2015;136:771-83.
11.Wang Q, Ma X, Chen Y, Zhang L, Jiang M, Li X, Xiang R, Miao R, Hajjar DP, Duan Y, Han J. Identification of interferon-? as a new molecular target of liver X receptor. Biochemical Journal 2014;459:345-354.
12.Chen Y#, Liu M#, Zhao T, Zhao B, Jia L, Zhu Y, Zhang B, Gao X, Li G, Li X, Xiang R, Han J, Duan Y. Danhong Injection inhibits the development of atherosclerosis in both Apoe-/- and Ldlr-/- mice. Journal of cardiovascular Pharmacology 2014;63:441–452.
13.Liu M#, Chen Y#, Yang X, Zhang L, Zhao T, Zhao B, Jia L, Zhu Y, Gao X, Zhang B, Li X, Han J, Duan Y. Danhong injection inhibits the development of primary abdominal aortic aneurysms in apoE knockout mice. Chinese Science Bulletin 2014;59:1366-1373.
14.Jiang M, Zhang L, Ma X, Hu W, Chen Y, Yu M, Wang Q, Li X, Yin Z, Zhu Y, Gao X, Hajjar DP, Duan Y, Han J. Tamoxifen inhibits macrophage FABP4 expression through the combined effects of the GR and PPAR? pathways. Biochemical Journal 2013;454:467-477.
15.Zhang L, Jiang M, Shui Y, Chen Y, Wang Q, Hu W, Ma X, Li X, Liu X, Cao X, Liu M, Duan Y, Han J. DNA topoisomerase II inhibitors induce macrophage ABCA1 expression and cholesterol efflux---an LXR-dependent mechanism. BBA - Molecular and Cell Biology of Lipids 2013;1831:1134-45.
16.Chen Y, Duan Y, Kang Y, Yang X, Jiang M, Zhang L, Li G, Yin Z, Hu W, Dong P, Li X, Hajjar DP, Han J. Activation of liver X receptor induces macrophage interleukin-5 expression. The Journal of Biological Chemistry 2012;287:43340-50.
17.Duan Y#, Chen Y#, Hu W, Li X, Yang X, Zhou X, Yin Z, Kong D, Yao Z, Hajjar DP, Liu L, Liu Q, Han J. Peroxisome Proliferator-activated receptor ??activation by ligands and dephosphorylation induces proprotein convertase subtilisin kexin type 9 and low density lipoprotein receptor expression. The Journal of Biological Chemistry 2012;287:23667-77.
18.Hu W, Zhou X, Jiang M, Duan Y, Chen Y, Li X, Yin Z, He GW, Yao Z, Zhu Y, Hajjar DP, Han J. Statins synergize dexamethasone-induced adipocyte fatty acid binding protein expression in macrophages. Atherosclerosis 2012;222:434-43.
19.Dong P, Xie T, Zhou X, Hu W, Chen Y, Duan Y, Li X, Han J. Induction of macrophage scavenger receptor type BI expression by tamoxifen and 4-hydroxytamoxifen. Atherosclerosis 2011;218:435-42.
20.杨潇潇，刘力沛，孙蕾，李小菊，段亚君，陈元利*. 过氧化物酶体增殖物激活受体gamma 激动剂和促分裂原活化蛋白激酶1/2抑制剂药物组合对Apoe-/-小鼠动脉粥样硬化发展的抑制作用. 中国动脉硬化杂志. 2015;23:763-768.

四、讲授课程
临床医学留学生《Experiment in cell biology》

五、联系方式
1． 通讯地址：中国天津市南开区卫津路94号生物站A303,300071
2． 电话：**
3． E-mail：yuanli2014@nankai.edu.cn