谈娟
性 别：女
职 称：副教授
所属部门：微生物学系
招生专业：微生物学
研究方向：反转录病毒及相关病毒的分子生物学、病毒与宿主的相互作用

::教师简介::
谈娟，女，2003年毕业于扬州大学，获理学学士学位；2008年毕业于南开大学生命科学学院微生物系，获理学博士学位；2008年6月至2010年6月，在南开大学化学学院化学生物学系从事博士后研究；同年7月留校任教。现任南开大学生命科学学院副教授。讲授“基因操作原理”、“病毒学”“分子病毒学”等课程。主要研究反转录病毒（包括慢病毒和泡沫病毒）感染过程中病毒与宿主细胞的相互作用。在Journal of Virology, Retrovirology, Cellular Microbiology, Virology, Virus Research, PLoS One, Journal of Virological Methods, Virus genes和Virologica Sinica等期刊上发表多篇文章。目前主持国家自然科学基金面上项目和青年科学基金项目各一项，主持天津市青年基金项目一项，并在博士后期间获得第45批中国博士后科学基金二等资助，作为主要参加人先后完成国家自然科学基金两项、高校博士点基金一项。通讯地址：南开大学生命科学学院419室 （邮政编码：300071）电话：**传真：**E-mail: juantan@nankai.edu.cn代表性论文：1.Liu R, Lin Y, Jia R, Geng Y, Liang C, Tan J*, Qiao W*. 2014. HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1. Retrovirology. 11:45. (*, co-corresponding authors)2.Hu X, Yang W, Liu R, Geng Y, Qiao W, Tan J*. 2014. N-Myc interactor inhibits prototype foamy virus by sequestering viral Tas protein in the cytoplasm. J Virol. 88(12):7036-44.3.Ma Q#, Tan J#, Cui X, Luo D, Yu M, Liang C, Qiao W*. 2014. Residues R(199)H(200) of prototype foamy virus transactivator Bel1 contribute to its binding with LTR and IP promoters but not its nuclear localization. Virology. 449:215-23. (#, co-first authors) 4.Liu R#, Tan J#, Lin Y, Jia R, Yang W, Liang C, Geng Y, Qiao W*. 2013. HIV-1 Vpr activates both canonical and noncanonical NF-κB pathway by enhancing the phosphorylation of IKKα/β. Virology. 439(1):47-56. (#, co-first authors)5.Guo HY, Ma YG, Gai YM, Liang ZB, Ma J, Su Y, Zhang QC, Chen QM, Tan J*. 2013. Bovine HEXIM1 inhibits bovine immunodeficiency virus replication through regulating BTat-mediated transactivation. Vet Res. 44:21.6.Lei Y#, Tan J#, Wink M, Ma Y*, Li N, Su G. 2013. An isoquinoline alkaloid from the Chinese herbal plant Corydalis yanhusuo W.T. Wang inhibits P-glycoprotein and multidrug resistance-associate protein 1. Food Chem. 136(3-4):1117-21. (#, co-first authors) 7.Yang W#, Tan J#, Liu R, Cui X, Ma Q, Geng Y, Qiao W*. 2012. Interferon-γ upregulates expression of IFP35 gene in HeLa cells via interferon regulatory factor-1. PLoS One. 7(12):e50932. (#, co-first authors) 8.Chang R#, Tan J#, Xu F, Han H, Geng Y, Li Y, Qiao W*. 2011. Lysine acetylation sites in bovine foamy virus transactivator BTas are important for its DNA binding activity. Virology. 418(1):21-6. (#, co-first authors) 9.Xu F#, Tan J#, Liu R, Xu D, Li Y, Geng Y, Liang C, Qiao W*. 2011. Tetherin inhibits prototypic foamy virus release. Virol J. 8:198. (#, co-first authors) 10.Wang J#, Tan J#, Guo H, Zhang Q, Jia R, Xu X, Geng Y*, Qiao W*. 2010. Bovine foamy virus transactivator BTas interacts with cellular RelB to enhance viral transcription. J Virol. 84(22):11888-97. (#, co-first authors) 11.Tan J, Hao P, Jia R, Yang W, Liu R, Wang J, Xi Z, Geng Y, Qiao W*. 2010. Identification and functional characterization of BTas transactivator as a DNA-binding protein. Virology. 405(2):408-13. 12.Wang W#, Tan J#, Wang J, Chen Q, Geng Y, Qiao W*. 2010. Analysis of bovine foamy virus btas mRNA transcripts during persistent infection. Virus Genes. 40(1):84-93. (#, co-first authors)13.Tan J, Qiao W, Wang J, Xu F, Li Y, Zhou J, Chen Q, Geng Y*. 2008. IFP35 is involved in the antiviral function of interferon by association with the viral tas transactivator of bovine foamy virus. J Virol. 82(9):4275-83.14.Tan J, Qiao W, Xu F, Han H, Chen Q, Geng Y*. 2008. Dimerization of BTas is required for the transactivational activity of bovine foamy virus. Virology. 376(1):236-41.
::主要学术论文::


::主要科研项目::