周军
性 别：男
职 称：教授
所属部门：遗传学和细胞生物学系
招生专业：细胞生物学
研究方向：细胞骨架与疾病

::教师简介::
周军，南开大学生命科学学院教授，药物化学生物学国家重点实验室PI，2008年度国家杰出青年基金获得者。先后就读于复旦大学、北京大学和美国Emory大学，获得博士学位后于Genentech公司和Emory大学进行科研训练，2005年回国至今为南开大学教授、博士生导师。曾任南开大学生命科学学院遗传学和细胞生物学系系主任、生命科学学院教代会主席、生命科学学院副院长等职务。2014年为美国佐治亚理工学院生物医学工程系访问教授。现为中国细胞生物学学会理事、细胞生物学教学与普及工作委员会副主任委员，中国遗传学会常务理事，天津市细胞生物学学会副理事长，天津市遗传学会副理事长。主要从事细胞骨架与人类疾病的研究，陆续主持国家自然科学基金青年基金、面上项目、杰出青年基金、重点项目，科技部973计划课题等，在国际学术刊物上发表六十余篇论文，主编两部英文书籍。主讲本科生课程<细胞生物学>、研究生课程<细胞生物学进展>等。曾获霍英东青年教师奖、南开大学教学成果奖、全国优秀博士学位论文提名奖指导教师等荣誉或称号。通讯地址：天津市卫津路94号南开大学生命科学学院生物站A403室，邮编300071.电子邮箱：junzhou@nankai.edu.cn；电话：**；网站：www.zhoulab.org近期论文：1.Yang Y, Ran J, Sun L, Sun X, Luo Y, Yan B, Tala, Liu M, Li D, Zhang L, Bao G, Zhou J. (2015). CYLD regulates noscapine activity in acute lymphoblastic leukemia via a microtubule-dependent mechanism. Theranostics 5(7):656-666.2.Ran J, Yang Y, Li D, Liu M, Zhou J. (2015). Deacetylation of alpha-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly. Scientific Reports 5:12917.3.Liu N, Xiong Y, Ren Y, Zhang L, He X, Wang X, Liu M, Li D, Shui W, Zhou J. (2015). Proteomic profiling and functional characterization of multiple post-translational modifications of tubulin. Journal of Proteome Research 14(8):3292-3304.4.Yang Y, Liu M, Li D, Ran J, Gao J, Suo S, Sun SC, Zhou J. (2014). CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation. Proceedings of the National Academy of Sciences of the USA (PNAS) 111(6):2158-2163.5.Yang Y, Ran J, Liu M, Li D, Li Y, Shi X, Meng D, Pan J, Ou G, Aneja R, Sun SC, Zhou J. (2014). CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6. Cell Research 24(11):1342-1353.6.Liu M, Li D, Sun L, Chen J, Sun X, Zhang L, Huo L, Zhou J. (2014). Modulation of Eg5 activity contributes to mitotic spindle checkpoint activation and Tat-mediated apoptosis in CD4-positive T-lymphocytes. Journal of Pathology 233(2):138-147.7.Tala, Xie S, Sun X, Sun X, Ran J, Zhang L, Li D, Liu M, Bao G, Zhou J. (2014). Microtubule-associated protein Mdp3 promotes breast cancer growth and metastasis. Theranostics 4(10):1052-1061.8.Sun X, Li D, Yang Y, Ren Y, Li J, Wang Z, Dong B, Liu M, Zhou J. (2012). Microtubule-binding protein CLIP-170 is a mediator of paclitaxel sensitivity. Journal of Pathology 226(4):666-673.9.Huo L, Li D, Sun L, Liu M, Shi X, Sun X, Li J, Dong B, Dong X, Zhou J. (2011). Tat acetylation regulates its actions on microtubule dynamics and apoptosis in T lymphocytes. Journal of Pathology 223(1):28-36.10.Shi X, Sun X, Liu M, Li D, Aneja R, Zhou J. (2011). CEP70 protein interacts with gamma-tubulin to localize at the centrosome and is critical for mitotic spindle assembly. Journal of Biological Chemistry 286(38): 33401-33408.11.Huo L, Li D, Sun X, Shi X, Karna P, Yang W, Liu M, Qiao W, Aneja R, Zhou J. (2011). Regulation of Tat acetylation and transactivation activity by the microtubule-associated deacetylase HDAC6. Journal of Biological Chemistry 286(11):9280-9286.12.Gao J, Sun L, Huo L, Liu M, Li D, Zhou J. (2010). CYLD regulates angiogenesis by mediating vascular endothelial cell migration. Blood 115(20):4130-4137.13.Sun L, Gao J, Huo L, Sun X, Shi X, Liu M, Li D, Zhang C, Zhou J. (2010). Tumor suppressor CYLD is a negative regulator of the mitotic kinase Aurora-B. Journal of Pathology 221(4):425-432.14.Liu M, Wang X, Yang Y, Li D, Ren H, Zhu Q, Chen Q, Han S, Hao J, Zhou J. (2010). Ectopic expression of the microtubule-dependent motor protein Eg5 promotes pancreatic tumorigenesis. Journal of Pathology 221(2):221-228.15.Dong X, Liu F, Sun L, Liu M, Li D, Su D, Zhu Z, Dong JT, Fu L, Zhou J. (2010). Oncogenic function of microtubule end-binding protein 1 in breast cancer. Journal of Pathology 220(3):361-369.16.Wang H, Liu B, Zhang C, Peng G, Liu M, Li D, Gu F, Chen Q, Dong JT, Fu L, Zhou J. (2009). Parkin regulates paclitaxel sensitivity in breast cancer via a microtubule-dependent mechanism. Journal of Pathology 218(1):76-85.17.Sun L, Gao J, Dong X, Liu M, Li D, Shi X, Dong JT, Lu X, Liu C, Zhou J. (2008). EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A. Proceedings of the National Academy of Sciences of the USA (PNAS) 105(20): 7153-7158.18.Liu M, Aneja R, Wang H, Sun L, Dong X, Huo L, Joshi HC, Zhou J. (2008). Modulation of multidrug resistance in cancer cells by the E3 ubiquitin ligase seven-in-absentia homolog 1. Journal of Pathology 214(4):508-514.19.Liu M, Aneja R, Sun X, Xie S, Wang H, Wu X, Dong JT, Li M, Joshi HC, Zhou J. (2008). Parkin regulates Eg5 expression by Hsp70 ubiquitination-dependent inactivation of c-Jun NH2-terminal kinase. Journal of Biological Chemistry 283(51):35783–35788.20.Gao J, Huo L, Sun X, Liu M, Li D, Dong JT, Zhou J. (2008). The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration. Journal of Biological Chemistry 283(14):8802-8809.
::主要学术论文::


::主要科研项目::