张涛
性 别：男
职 称：教授
所属部门：动物生物学和发育生物学系
招生专业：生物信息学/神经信息学
研究方向：神经生理与计算神经生物学

::教师简介::
张涛,男，1982和88年获浙江大学学士（固体力学）、硕士（计算力学），1997年获英国伯明翰大学博士（生理学）。现为南开大学教授，博士生导师 （动物与发育生物学系主任）。曾在英国曼彻斯特大学、日本理化学研究院脑研究所和英国伦敦SBU大学从事博士后、研究员和高级研究员工作。回国以来已经完成多项国家级基金和省部级科学基金，目前主持两项国家级基金和一项天津市基础研究重点项目。在国内外学术刊物上发表论文壹佰余篇。组建了以硕士和博士生为主体的研究队伍。硕士生、博士生招生专业：计算神经生物学,神经生理学电话：＋**电子邮件：zhangtao@nankai.edu.cn在研项目信息：项目名称：神经信息流与突触传递可塑性经费来源：国家自然科学基金面上项目起止年月：2012.01.01－2015.12.31负责内容：项目负责人经费：66万项目名称：关于知觉认知与知觉决策的神经动力学研究与实验分析经费来源：国家自然科学基金重点项目起止年月：2013.01 - 2017.12负责内容：项目负责人(南开大学）经费：103万项目名称：神经振荡与突触可塑性及其对认知功能损伤检测的意义经费来源：天津市科委重点项目起止年月：2012.01.01－2014.12.31负责内容：项目负责人经费：20万近期发表主要论文(* 通讯作者）:Xiaxia Xu, Chunhua Liu, Zhanyong Li, Tao Zhang*. Effects of hydrogen sulfide on modulation of theta-gamma coupling in hippocampus in vascular dementia rats. Brain topography. 2015. DOI: 10.1007/s10548-015-0430-x.Chenguang Zheng, Tao Zhang*. Synaptic plasticity related neural oscillations on hippocampus-prefrontal cortex pathway in depression. Neuroscience. 2015. 292：170-180. Hui Wang, Na Gao, Zhigui Li, Zhuo Yang, Tao Zhang*. Autophagy alleviates melamine-induced cell death in PC12 cells via decreasing ROS level. Molecular Neurobiology. 2015. DOI: 10.1007/s12035-014-9073-2.Lei An, Tao Zhang*. Reversible effects of vitamins C and E combination on cognitive deficits and oxidative stress in the hippocampus of melamine-exposed rats. Pharmacology, Biochemistry and Behavior. 2015. DOI:10.1016/j.pbb.2015.03.009 Lei An, Tao Zhang*. Prenatal melamine exposure induces impairments of spatial cognition and hippocampal synaptic plasticity in male adolescent rats. Reproductive Toxicology. 2014. 49:78-85Ting Chen, Jiajia Yang, Hui Zhang, Guogang Ren, Zhuo Yang, Tao Zhang*. Multi-walled carbon nanotube inhibits CA1 glutamatergic synaptic transmission in rat’s hippocampal slices. Toxicology Letter, 2014, 229: 423-429. Lei An, Tao Zhang*. Vitamins C and E reverse melamine-induced deficits in spatial cognition and hippocampal synaptic plasticity in rats. Neurotoxicology, 2014, 44:132-139.Xichao Mi, Ning Cheng, Tao Zhang*. Performance comparison of both gPDC and PCMI algorithms for measuring directionality of neural information flow. Journal of Neuroscience Method. 2014, 227: 57-64Jiajia Yang, Yang Yao, Ting Chen, Tao Zhang*. VEGF ameliorates cognitive impairment in in vivo and in vitro ischemia via improving neuronal viability and function. NeuroMolecular Medicine. 2014, 16:376-388.Xiaxia Xu, Lei An, Xichao Mi, Tao Zhang*. Impairment of cognitive function and synaptic plasticity associated with alteration of information flow in theta and gamma oscillations in melamine-treated rats. Plos One. 2013, 8(10):e77796Xiaxia Xu, Chenguang Zheng, Tao Zhang*. Reduction in LFP cross-frequency coupling between theta and gamma rhythms associated with impaired STP and LTP in a rat model of brain ischemia. Frontiers in Computational Neuroscience. 2013, Volume 7: Article 27Chenguang Zheng, Tao Zhang*. Alteration of phase-phase coupling between theta and gamma rhythms in a depression-model of rats. Cognitive Neurodynamics. 2013, 7(2):167-172.Jiajia Yang, Zhaowei Liu, Yongling Xie, Zhuo Yang, Tao Zhang*. Peroxynitrite alters GABAergic synaptic transmission in immature rat hippocampal slices: a possible involvement of presynaptic VGCCs. Neuroscience Research. 2013, 75:210-217Ting Chen, Jiajia Yang, Guogang Ren, Zhuo Yang, Tao Zhang*. Multi-walled carbon nanotube increases the excitability of hippocampal CA1 neurons through inhibition of potassium channels in rat’s brain slices. Toxicology Letter. 2013, 217(3):212-128Lei An, Zhuo Yang, Tao Zhang*. Imbalanced synaptic plasticity induced spatial cognition impairment in male offspring rats treated with chronic prenatal ethanol exposure. Alcoholism: Clinical and Experimental Research. 2013. 37(5): 763-770Lei An, Zhuo Yang, Tao Zhang*. Melamine Induced Impairments of Spatial Cognition and Long-term Depression Associated With Alteration of Cholinergic System in Wistar Rats. Neurobiology of Learning and Memory. 2013, 100:18-24Chenguang Zheng, Meina Quan, Tao Zhang*. Decreased thalamo-cortical connectivity by alteration of neural information flow in theta oscillation in depression-model rats. Journal o f Computational Neuroscience. 2012, 33(3):547-558.Xiaxia Xu, Zhanyong Li, Zhuo Yang, Tao Zhang*. Decrease of Synaptic Plasticity Associated with Alteration of Information Flow in a Rat Model of Vascular Dementia. Neuroscience. 2012, 206: 136-143Lei An, Shichang Liu, Zhuo Yang, Tao Zhang*. Cognitive impairment in rats induced by nano-CuO and its possible mechanisms. Toxicology Letter. 2012, 213(2): 220-227Ning Zhang, Yuanming Feng, Shan Gao, Jishou Ruan and Tao Zhang*. New insights regarding protein folding as learned from beta-sheets. EXCLI Journal. 2012, 11:543-555Tian Yutao, Lei Ting, Yang Zhuo, Zhang Tao*. Urethane decreases hippocampal CA1 neuron excitability via alter presynaptic of glutamate release and potassium channels. Brain Research Bulletin. 2012, 87: 420-426Lei An, Zhanyong Li, Zhuo Yang, Tao Zhang*. Melamine induced cognitive impairment associated with oxidative damage in rat's hippocampus. Pharmacology, Biochemistry and Behavior. 2012，102(2):196-202Chenguang Zheng, Meina Quan, Zhuo Yang, Tao Zhang*. Directionality index of neural information flow as a measure of synaptic plasticity in chronic unpredictable stress rats. Neuroscience Letter. 2011, 490:52-56Mei Zhang, Chenguang Zheng, Meina Quan, Lei An, Zhuo Yang, Tao Zhang*. Directional indicator on neural oscillations as a measure of synaptic plasticity in chronic unpredictable stress rats. NeuroSignals. 2011, 19:189-197Yi-yi Wang, Shi-chang Liu, Zhuo Yang, Tao Zhang*. Impaired hippocampal synaptic plasticity in C6 glioma-bearing rats. J Neuro-Oncology. 2011, 103(3):469–477.Zhanyong Li, Yiyi Wang, Yongling Xie, Zhuo Yang, Tao Zhang*. Protective Effects of Exogenous Hydrogen Sulfide on Neurons of Hippocampus in a Rat Model of Brain Ischemia. Neurochemistry Research. 2011, 36(10):1840–1849Lei Zhang, Ning Zhang, Ji-Shou Ruan, Tao Zhang*. Studies on the Rules of β-Strand Alignment in a Protein β-Sheet Structure. Journal of Theoretical Biology. 2011, 285(1):69-76Yi-Yi Wang, Ning Li，Jie Huang，Zhuo Yang, Tao Zhang*. Effects of ionic products from silicon-substituted hydroxyapatite on the rat brain activity: Morris water maze studies and long term potentiation in hippocampal CA1. Materials Science & Engineering: C (Materials for Biological Applications). 2011, 31: 1558–1566Jiajia Yang, Lei An, Yang Yao, Zhuo Yang, Tao Zhang*. Melamine impairs spatial cognition and hippocampal synaptic plasticity by presynaptic inhibition of glutamatergic transmission in infant rats. Toxicology. 2011, 289: 167-174Lei An, Zhanyong Li, Zhuo Yang, Tao Zhang*. Cognitive Deficits Induced by Melamine in Rats. Toxicology Letter. 2011, 206: 276-280发表论文详细情况（含全文下载）：http://www.nkbiox.com/Chinese/pubs.asp?cn=zhangtao&classID=1
::主要学术论文::


::主要科研项目::