杨志谋
性 别：男
职 称：教授
所属部门：生物化学和分子生物学系
招生专业：
研究方向：水凝胶；生物材料；药物释放

::教师简介::
1997.9-2001.7 南京大学高分子系学士2001.7-2002.12南京大学高分子系 科研助手（临时）2003.2-2006.8 香港科技大学化学系博士2006.8-2007.3 香港科技大学化学系博士后2007.3-2008.12斯坦福大学微生物与病原体系 博士后2009.3至今南开大学, 教授, 博士生导师杨志谋课题组主要从事小分子水凝胶的制备及其在组织工程、药物释放、癌症治疗等领域的应用。目前为止主要在下列方向上希望能开展深入工作：1）基于抗癌药物的小分子水凝胶；2）短肽小分子水凝胶体内外生物相容性评价；3）小分子水凝胶对干细胞分化的调控；4）基于蛋白-多肽特异性结合的水凝胶;5) 细胞和微生物表面工程。本课题组从生物化学及分子生物学以及高分子化学两个方向招生，欢迎热衷科研的学生报考。我们欢迎具有高分子合成、有机合成、以及细胞培养方面经验的博士生加盟（博士后）。Email： yangzm@nankai.edu.cnFor a brief description of our research, please click the link below:lab home page: http://yang-lab.orgResearch ID: http://www.researcherid.com/rid/F-1798-2010Refereed publications after joining NKU：12. Zheng, W. T.~; Gao, J.~; Song, L. J.; Chen, C. Y.; Guan, D.; Wang, Z. H.; Li, Z. B.*; Kong, D. L.*; and Yang, Z. M.* "Surface-induced hydrogelation inhibits platelets aggregation" J. Am. Chem. Soc.,DOI: 10.1021/ja308690y.( ~equal contributions)11. Wang, H. M.; Shi, Y.; Wang, L.; and Yang, Z. M.*"Recombinant proteins as cross linkers for hydrogelations" Chem. Soc. Rev. DOI:10.1039/C2CS35358J.10. Wang, H. M.~; Wei, J.~; Yang, C. B.; Zhao, H. Y.; Li, D. X.; Yin, Z. N.; and Yang, Z. M.*"The Inhibition of Tumor Growth and Metastasis by Self-assembled Nanofibers of Taxol" Biomaterials, 2012, 33(24), 5848-5853.( ~equal contributions)9. Zhang, X. L.; Chu, X. L.; Wang, L.; Wang, H. M.; Liang, G. L.; Zhang, J. X.; Long, J. F.*; and Yang, Z. M.* "Rational Design of A Tetrameric Protein to Enhance Interactions Between Self-assembled Fibers Gives Molecular Hydrogels" Angew. Chem. Int. Ed., 2012, 51, 1-6.8. Wang, H. M. and Yang, Z. M.* "Molecular hydrogels of hydrophobic compounds: a novel self-delivery system for chemotherapy", Soft Matter, 2012, 8, 2344-2347. (Invited Highlight)7. Mao, L. N,; Wang, H. M.; Tan, M.; Ou, L. L.; Kong, D. L. and Yang, Z. M.* "Conjugation of Two Complementary Anti-Cancer Drugs Confers Molecular Hydrogels as A Co-delivery System", Chem. Commun. 2011, 48(3), 395-397.6. Wang, Z. H.; Zheng, W. T.; Wang, H. M.; Wang, S. F.; Zhao, Q.; Zhang, J.; Yang, Z. M.* ; Kong, D. L.* "Highly stable surface modification of PCL by molecular self-assembly of a gelator" Chem. Commun., 2011, 47 (31), 8907-8903.5. Wang, H. M.; Yang, C. H.; Wang, L.; Kong, D. L.; Yang, Z. M.* " Self-assembled Nanospheres as a Novel Delivery System for Taxol: A Molecular Hydrogel with Nanosphere Morphology" Chem. Commun., 2011, 47 (15), 4439-4441.4. Ren, C. H.; Song, Z. J.; Zheng, W. T.; Wang, L.; Kong, D. L.; Yang, Z. M.* "Disulfide bond as a cleavable linker for molecular self-assembly and hydrogelation" Chem. Commun., 2011, 47, 1619-1621.3. Wang, H. M.; Wang, Z.; Yi, X. Y.; Long, J. F.; Liu, J. F.; Yang, Z. M.* "Anti-degradation of a recombinant complex protein by incorporation in small molecular hydrogels" Chem. Commun., 2011, 47, 955-957.2. Wang, J. Y.; Wang, Z. H.; Wang, L.;* Yang, Z. Y.; Kong, D. L.;* and Yang, Z. M.* "Incorporation of Supramolecular Hydrogels into Agarose Hydrogels Affords Novel Materials as Potential Drug Delivery Carriers" J. Mater. Chem., 2009, 19, 7892-7896.1. Gao, J.; Wang, H. M.; Wang, L.;* Wang, J. Y.; Kong, D. L.;* and Yang, Z. M.* "Enzyme Promotes the Hydrogelation from a Hydrophobic Small Molecule" J. Am. Chem. Soc. 2009, 131, 11286-11287.
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