西安交通大学生命科学与技术学院导师教师师资介绍简介-张鹏晖

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Welcome - 张鹏晖基本信息
张鹏晖，男，博士，西安交通大学，生命科学与技术学院，副教授。本人致力于新型智能纳米材料的开发，肿瘤标志物筛选与检测，药物控制释放，微凝胶组装，即时诊断等交叉学科的研究。

联系方式

通讯地址：西安市咸宁西路28号，西安交通大学，东二楼，143室。
联系方式：**
邮箱：phzhang@xjtu.edu.cn

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张鹏晖博士加入BEBC
2017-01-18

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研究领域

本人博士期间参与了国家基金委的面上项目、重点项目、重大仪器专项等科研项目，在肿瘤标志物的筛选、药物靶向递送和控制释放领域取得了一系列成果，现已发表文章20篇，其中第一作者文章11篇（含导师第一），包括Nat.Chem.，Angew. Chem. Int. Ed. 1篇，ACS Nano 2篇，Adv. Mater. 1篇，总影响因子超过150，ESI高引论文2篇（Angew. Chem. Int. Ed.2014,53(9), 2371-2375；Carbon2013, 64, 424-434）。现承担国家自然科学基金面上项目、青年基金，中国博士后科学基金、陕西省博后基金特别资助项目、中国博士后科学基金特别资助。
本人于2017年11月进入交大生物医学工程与生物力学研究中心（BEBC），现研究方向为：1. 智能聚合物的合成及其在基因运载、药物靶向递送与可控释放中的应用研究；2. 纳米粒子表面性质的精确操控及其用于肿瘤的精准治疗；3. 智能响应的水凝胶的制备及其应用。本研究小组长期招收有化学、生物、材料背景的本科生和研究生进组参加科研训练，亦欢迎科研合作和交流。

Publication - 张鹏晖
Journal Papers
2020
28. Zhang, Penghui^#; Gao, Di^#; An, Keli^#; Shen, Qi; Wang, Chen; Zhang, Yuchao; Pan, Xiaoshu; Chen, Xigao; Lyv, Yifan; Cui, Cheng; Liang, Tingxizi; Duan, Xiaoman; Liu, Jie; Yang, Tielin; Hu, Xiaoxiao; Zhu, Jun-Jie*; Xu, Feng*; Tan, Weihong*; A programmable polymer library that enables the construction of stimuli-responsive nanocarriers containing logic gates, Nature Chemistry2020, 12, 381-390.(IF=23.361)
2019
27. Zheng, Fenfen; Wang, Chen; Meng, Tiantian; Zhang, Yuqian; Zhang, Penghui; Shen, Qi; Zhang, Yuchao; Zhang, Junfeng; Li, Jianxin; Min, Qianhao*; Chen, Jiangning*; Zhu, Jun-Jie*;Outer-frame-degradable nanovehicles featuring near-infrared dual luminescence for in vivo tracking of protein delivery in cancer therapy, ACS Nano 2019, 13, 12577-12590.(IF=13.903)
26. Zheng, Fenfen*; Xiong, Weiwei; Sun, Shasha; Zhang, Penghui; Zhu, Jun-Jie*;Recent advances in drug release monitoring,Nanophotonics 2019, 8, 391-413.?(IF=6.908)
2018
25. Yang, Lu; Sun, Hao; Liu, Yuan; Hou, Weijia; Yang, Yu; Cai, Ren; Cui, Cheng; Zhang, Penghui; Pan, Xiaoshu; Li, Xiaowei; Li, Long; Sumerlin, Brent S*; Tan, Weihong*;Self-assembled aptamer-grafted hyperbranched polymer nanocarrier for targeted and photoresponsive drug delivery, Angewandte Chemie International Edition 2018, 57, 17048-17052.(IF=12.257)
24. Li, Long; Jiang, Ying; Cui, Cheng; Yang, Yu; Zhang, Penghui; Stewart, Kimberly; Pan, Xiaoshu; Li, Xiaowei; Yang, Lu; Qiu, Liping*; Tan, Weihong*;Modulating aptamer specificity with pH-responsive DNA bonds,Journal of the American Chemical Society 2018, 140, 13335-13339.(IF=14.695)
23. Zhang, Penghui; An, Keli; Duan, Xiaoman; Xu, Hao; Li, Fei; Xu, Feng*;Recent advances in siRNA delivery for cancer therapy using smart nanocarriers, Drug Discovery Today, 2018, 23, 900-911.( IF=6.880, ESI高被引论文)
22. He, Z.; Xiao, Y.; Zhang, J.*; Zhang, P.*; Zhu, J.-J.*;In situ formation of large pore silica-MnO2 nanocomposites with H+ /H₂O₂sensitivity for O₂-elevated photodynamic therapy and potential MR imaging, Chemical Communications 2018, 54, 2962-2965.( IF=6.567, 封面文章)
21. He Z.^#;Zhang P.^#; Xiao, Y.; Li, J.; Yang, F.; Liu, Y.; Zhang, J.; Zhu, J.-J., Acid-degradable gadolinium-based nanoscale coordination polymer: a potential platform for targeted drug delivery and potential MR imaging.Nano Research2018, 11, 929-939. (IF=8.893)
2017
20.Zhang P.; Wang Y.; Lian J.; Shen Q.; Wang C.; Ma B.; Zhang Y.; Shao Y.; Xu, F.; Zhu, J.-J., Engineering the surface of smart nanocarriers using pH-/Thermal-/GSH-responsive polymer zipper for precise tumor target therapy in vivo. Advanced Materials 2017, 29, **. (IF=18.960，封面文章)
19. Zheng, F.^#; Zhang, P.^#; Xi, Y.; Chen, X.; He, Z.; Meng, T.; Chen, J.; Li, L.*; Zhu, J.-J.*; Hierarchicalnanocarriers for precisely regulating the therapeutic process via dual-mode controlled drug release in target tumor cells, ACS Applied Materials & Interfaces 2017, 9, 36655-36664.(IF=7.145)
18. Zheng, F.;Zhang P.; Xi, Y.; Huang, K.; Min, Q.*; Zhu, J.-J.*, Peptide-mediated core/satellite/shell multifunctional nanovehicles for precise imaging of cathepsin B activity and dual-enzyme controlled drug release.NPG Asia Materials2017,9, e366.(IF=8.772)
Before 2016
17.Zhang, P.; Wang, C.; Zhao, J.; Xiao, A.; Min, Q,; Chen, J.; Chen, H.-Y.; Zhu, J.-J., Near Infrared-guided smart nanocarriers for microRNA-controlled release of Doxorubicin/siRNA with intracellular ATP as fuel. ACS Nano 2016, 10 (3), 3637-3647.(IF=13.334)
16.Zhang, P.; He, Z.; Wang, C.; Chen, J.; Zhao, J.; Zhu, X.; Li, C.-Z; Min, Q.; Zhu J.-J.*, In situ amplification of intracellular microRNA with MNAzyme nanodevices for multiplexed imaging, logic operation, and controlled drug release. ACS Nano 2015, 9, 789-798. (IF=13.334)
15.Zhang, P.; Cheng, F.; Zhou, R.; Burda, C.; Min, Q.; Zhu, J.-J.*, DNA-hybrid-gated multifunctional mesoporous silica nanocarriers for dual-targeted and microRNA-responsive controlled drug delivery. Angewandte Chemie International Edition 2014, 53 (9), 2371-2375. (IF=11.709)
14.Zhang, P.; Cao, J.-T.; Min, Q.-H.; Zhu, J.-J.*, Multi-shell structured fluorescent–magnetic nanoprobe for target cell imaging and on-chip sorting. ACS Applied Materials & Interfaces2013, 5 (15), 7417-7424. (IF=7.145)
13.Dong, S.*; Zhang, P.; Liu, H.; Li, N.; Huang, T., Direct electrochemistry and electrocatalysis of hemoglobin in composite film based on ionic liquid and NiO microspheres with different morphologies. Biosensors & Bioelectronics 2011, 26 (10), 4082-4087. (tutor first, IF=7.476)
12. Dong, S.*; Zhang, P.; Yang, Z.; Huang, T., Simultaneous determination of catechol and hydroquinone by carbon paste electrode modified with hydrophobic ionic liquid-functionalized SBA-15. Journal of Solid State Electrochemistry 2012, 16 (12), 3861-3868. (tutor first, IF=2.327)
11.Zhang, P.; Dong, S.*; Gu, G.; Huang, T., Simultaneous determination of Cd²⁺, Pb²⁺, Cu²⁺ and Hg²⁺ at a carbon paste electrode modified with ionic liquid-functionalized ordered mesoporous silica. Bulletin of the Korean Chemical Society2010, 31 (10), 2949-2954. (IF=0.793)
10. Zhao, J.^#; Zhang P.^#; He, Z.; Min, Q.; Abel-Halim E. S.; Zhu, J.-J., Thermal-activated nanocarriers for the manipulation of cellular uptake and photothermal therapy on command. Chemical Communications 2016,52, 5722-5725. (co-author, IF=6.567)
9. He, Z.; Zhang, P.; Li, X.; Zhang, J.; Zhu, J.-J., A targeted DNAzyme-nanocomposite probe equipped with built-in Zn2+ arsenal for Combined Treatment of Gene Regulation and Drug Delivery. Scientific Reports 2016, 6, 22737. (IF=5.228)
8. Zheng, F.; Zhang P.; Xi Y.; Chen J.; Li, L.; Zhu, J.-J.*, Aptamer/Graphene quantum dots nanocomposite capped fluorescent mesoporous silica nanoparticles for Iintracellular drug delivery and real-time monitoring of drug release. Analytical Chemistry2015, 87 (23), 11739-11745. (IF=5.886)
7. Cao, J.; Zhang, P.; Liu, Y.; Abdel, H.; Zhu, J.-J.*, Versatile microfluidic platform for the assessment of sialic acid expression on cancer cells using quantum dots with phenylboronic acid tags. ACS Applied Materials & Interfaces 2015, 7, 14878-14884. (IF=7.145)
6. Ban, R.; Li, J.; Cao, J.; Zhang, P.; Zhang, J.; Zhu, J.-J., Highly luminescent glutathione-capped ZnS:Mn/ZnS core/shell doped quantum dots for targeted mannosyl groups expression on the cell surface. Analytical Methods 2013, 5, 5929-5937. (IF=1.915)
5. Li, J.; Wang W.; Sun, D.; Chen, J.; Zhang, P.; Zhang, J.; Zhu, J-.J., Aptamer-functionalized silver nanoclusters-mediated cell type-specific siRNA delivery and tracking. Chemical Science 2013, 4, 3514-3521. (IF=9.144)
4. Sun, D.; Ban, R.; Zhang, P.; Wu, G.; Zhang, J.; Zhu, J.-J., Hair fiber as a precursor for synthesizing of sulfur- and nitrogen-co-doped carbon dots with tunable luminescence properties. Carbon 2013, 64, 424-434. (IF=6.198)
3. Cao, J.; Chen, Z.; Hao, X.; Zhang, P.; Zhu, J.-J.*, Quantum dots-based immunofluorescent microfluidic chip for the analysis of glycan expression at single-cells. Analytical Chemistry 2012, 84, 10097-10104. (IF=5.886)
2. Dong, S.; Yang, Z.; Zhang, P.; Hu, Q.; Huang, T., Comparative study of hollow-fiber liquid-phase micro-extraction and an aqueous two-phase system for determination of phytohormones in soil. Analytical and Bioanalytical Chemistry 2012, 403, 1743-1749. (IF=3.125)
1. Dong, S.; Li, N.; Zhang, P.; Li, Y.; Chen, Z.; Huang, T., Fabrication of hemoglobin/Ionic liquid modified carbon paste electrode based on the electrodeposition of gold nanoparticles/ CdS quantum dots and its electrochemical application. Electroanalysis 2012, 24(7), 1554-1560. (IF=2.417)

Journal - 张鹏晖