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西北农林科技大学生命学院导师教师师资介绍简介-陈红英

本站小编 Free考研考试/2021-07-07

  一、个人简介
  陈红英,女,博士,教授,1970年生。1988-1992年,中国农业大学动物生理学与生物化学专业本科;1992-1998年,中国农业大学动物生理学与生物化学专业硕博连读;1998-2000年,中国科学院发育生物学研究所,博士后;2000-2009年, 英国雷丁大学(University of Reading),Research fellow。2009年9月到西北农林科技大学生命科学学院工作,入选2009年教育部新世纪优秀人才支持计划。
  二、研究方向
  动物病毒(如PRRSV, AcMNPV)蛋白的结构功能,病毒-宿主互作关系
  三、发表论文
  发表科研论文30余篇。代表性论文:
  1. Dong S, Liu L, Wu W, Armstrong SD, Xia D, Nan H, Hiscox JA, Chen H* Determination of the interactome of non-structural protein12 from highly pathogenic porcine reproductive and respiratory syndrome virus with host cellular proteins using high throughput proteomics and identification of HSP70 as a cellular factor for virus replication. Journal of Proteomics 146: 58–69, 2016.
  2. Liu L, Tian J, Nan H, Tian M, Li Y, Xu X, Huang B, Zhou E, Hiscox JA, Chen H*. Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein Interacts with Nsp9 and Cellular DHX9 to Regulate Viral RNA Synthesis. J Virol. 2016, 90:5384–5398.
  3. Xu X*, Zhou X, Nan H, Zhao Y, Bai Y, Ou Y, H Chen*. Aggregation of AcMNPV LEF-10 and Its Impact on Viral Late Gene Expression. PLoS ONE 11(5): e**, 2016.
  4. Chen J, Xu X, Tao H, Wang Y, Chen H*. Chemical shift assignments of nsp7α from porcine reproductive and respiratory syndrome virus. Biomol NMR Assign. 2016, 10(2):391-394.
  5. Liu L, Lear Z, Hughes DJ, Wu W, Zhou E, Whitehouse A, Chen H*, Hiscox JA* Resolution of the cellular proteome of the nucleocapsid protein from a highly pathogenic isolate of porcine reproductive and respiratory syndrome virus identifies PARP-1 as a cellular target whose interaction is critical for virus biology. Veterinary Microbiology 2015, 176(1-2): 109-119.
  6. Y Wang, Y Mao, X Xu, S Tao*, H Chen* Codon Usage in Signal Sequences Affects Protein Expression and Secretion Using Baculovirus/Insect Cell Expression System. Plos One 10(12): e**, 2015.
  7. Fang W, Peng K, Tian J, Xu X, Zhou E, Chen H* Immune response to Fc tagged GP5 glycoproteins of porcine reproductive and respiratory syndrome virus. Viral Immunology 2014, 27 (7): 343–349.
  8. Liu B, Wang R, Wu F, Xu X, Chen H* Rapid production of HIV-1 neutralizing antibodies in baculovirus infected insect cells. Protein Expression and Purification 2014, 99:87-93.
  9. Xu X, Chen Y, Zhao Y, Liu X, Dong B, Jones IM, Chen H* Baculovirus superinfection: A probable restriction factor on the surface display of proteins for library screening. Plos One 8(1): e54631, 2013.
  10. Chen H, Xu X, Lin HH, Chen SH, Forsman A, Chapman MA, Jones IM*. Mapping the immune response to the outer domain of a human immunodeficiency virus-1 clade C gp120. J. Gen. Virol. 2008 Oct;89(Pt 10):2597-2604
  11. Chen H, Xu X, Jones IM*. Immunogenicity of the outer domain of a HIV-1 clade C gp120. Retrovirology 2007; 4: 33.
  12. Chen H, Xu X, Bishop A, Jones IM*. Reintroduction of the 2G12 epitope in an HIV-1 clade C gp120. AIDS. 2005 May 20;19(8):833-5.
  13. Chen H, Gill A, Dove BK, Emmett SR, Kemp CF, Ritchie MA, Dee M, Hiscox JA*. Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. J Virol. 2005 Jan;79(2):1164-79.
  14. Chen H, Coote B, Attree S, Hiscox JA *. Evaluation of a nucleoprotein-based enzyme-linked immunosorbent assay for the detection of antibodies against infectious bronchitis virus. Avian Pathol. 2003 Oct;32(5):519-26.
  15. Chen H, Wurm T, Britton P, Brooks G, Hiscox JA *. Interaction of the coronavirus nucleoprotein with nucleolar antigens and the host cell. J Virol. 2002 May;76(10):5233-50.
  16. Chen HY, Zhou Q, Zhang MF, and Giambrone JJ *. Sequence Analysis of the VP2 Hypervariable Region of Nine Infectious Bursal Disease Virus Isolates from Mainland China. Avian Diseases 42:762-769, 1998.
  四、专利
  陈红英,许晓东,杨雄 一种识别HIV-1受体结合表位的可溶性单链抗体的制备方法,专利号:ZL 2013 1 **.1。
  五、联系方式
  单位:西北农林科技大学生命学院
  地址: 陕西杨凌西农路22号,712100
  电子邮件:chenhy@nwsuaf.edu.cn



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