陈瑱贤 工程师 工程机械学院




个人资料
个人概况
研究领域
开授课程
科研项目
论文
科技成果
荣誉奖励
工作经历










学位： 博士
毕业院校： 西安交通大学
邮件： zhenxian_chen@yeah.net
电话：
出生年月：
办公地点： 机械学院318







个人资料
学院： 工程机械学院
性别： 男
出生年月：
职称： 工程师
学位： 博士
学历： 研究生
毕业院校： 西安交通大学
联系电话：
电子邮箱： zhenxian_chen@yeah.net
通讯地址： 陕西省西安市南二环中段长安大学工程机械学院
邮编： 710064
传真：
办公地址： 机械学院318
教育经历： 1.2010/09-2016/06，西安交通大学，机械工程专业，硕博连读
2.2006/09-2010/06，成都理工大学，机械工程及其自动化专业，本科




个人简介
个人介绍：
陈瑱贤，男，汉族，中共党员，1986年出生，2016毕业于西安交通大学机械工程学院并获得工学博士学位，现工作于机械制造系，硕士研究生导师。中国力学学会会员，中国生物医学工程学会会员。
主要从事医疗器械的数字化设计与制造方面的研究工作，包括医疗器械的结构优化和智能设计方法、医疗器械力学与摩擦学功能评价、定制化器械的3D打印制造等方面。
近年来主持国家自然科学青年基金1项，陕西省青年基金1项，中央高校基础研究基金1项，医院合作课题1项，参与陕西省青年基金2项，中央高校创新团队项目1项，在国内外学术期刊上发表论文37篇，其中以第一作者和通讯作者发表SCI论文15篇，被同行引用183次（Web of Science）, 单篇最高引用37次，H-index 9；参编专著2部，参编国家医药行业标准1项，申请国家专利4项，博士毕业论文曾获西安交通大学优秀博士论文。
ResearchGate: https://www.researchgate.net/profile/Zhenxian_Chen。
每年招收研究生3-4名，欢迎机械、力学相关专业的同学报考，Email: Zhenxian_chen@yeah.net

先进设计与制造技术研究团队介绍：
先进设计与制造技术研究团队主要开展光学电子、航空航天、生物医疗、工程机械领域的先进设计与超精密制造方法、3D打印成型工艺、计算机辅助工业设计等研究。团队有教授1名，副教授1名，高级工程师1名，讲师2名，工程师2名。团队微信公众号：AMTLab。

陈世斌
教授
http://js.chd.edu.cn/gcjxxy/csb/list.htm

郭磊
副教授
http://js.chd.edu.cn/gcjxxy/gl_2452/list.htm

李珂
高级工程师
http://js.chd.edu.cn/gcjxxy/lk/list.htm

高永昌
讲师
http://js.chd.edu.cn/gcjxxy/gyc100/list.htm

张静
讲师
http://js.chd.edu.cn/gcjxxy/zj_9494/list.htm

陈瑱贤
工程师
http://js.chd.edu.cn/gcjxxy/ctx/list.htm

靳淇超
工程师
http://js.chd.edu.cn/gcjxxy/jqc/list.htm


团队活动：





社会职务
1.期刊论文审稿人：
《Computers in Biology and Medicine》
《Medical Engineering & Physics》
《Part H: Journal of Engineering in Medicine》
《Applied Bionics and Biomechanics》
《Journal of Orthopaedic Surgery and Research》
《Journal of Medical Imaging and Health Informatics》
《Biosurface and Biotribology》




研究领域
研究方向：
康复器械/植入物数字化设计、定制化康复器械/植入物的3D打印制造、康复器械/植入物生物力学/生物摩擦学功能评估


方向特点：
以机械工程学科为主体，医工结合、学科交叉、技术前沿。

涉及内容包括：
人工关节、填充块、固定板等医疗器械产品的结构设计、有限元分析、在体环境下的骨骼肌肉动力学分析、3D打印



硕士招生：
欢迎对研究方向感兴趣的机械、力学等专业学生报考，要求具有良好的沟通和团队合作能力，具备CAD制图技能和数学英语功底，熟悉SolidWorks、Abaqus、 Matlab、python者优先。


在读研究生：
年级
姓名
课题


2020
任佳轩
膝关节置换定位截骨器械设计


2020
袁霄
胫骨高位截骨固定板设计


2020
屈亚飞
单髁膝关节生物力学研究


2020
董哲
DDH髋关节生物力学
（高老师指导）

2021
董天琦

（张老师指导）

2021
薛敏



2021
张兵











开授课程
《医疗器械的个体化设计》
《3D打印快速制造与实践》



科研项目
1. 国家自然科学基金青年项目，**，UKA手术校准对膝关节宏微运动生物力学的影响规律及假体松动和软骨退化风险防控机理研究，2020/1-2022/12，主持。
2. 陕西省自然科学基金青年项目，2019JQ-243，人工膝关节精准置换的个体化定位截骨器械的快速数字化设计，2019/1-2020/12, 主持。
3. 中央高校基础研究培育项目，4，基于3D打印的人工膝关节个体化手术校准器械的设计方法研究，2018/1-2019/12，主持。
4. 唐都医院横向课题，2，人体下肢骨骼肌肉动力学仿真研究，2020/7-2020/12，主持。
5. 中央高校创新团队支持项目，2，基于先进制造技术的仿生设计研究，2017/1-2018/12，参与。




论文
Journal articles (*corresponding author)

[37] Chen Zhenxian, Fan Xunjian, Gao Yongchang, et al. Effect of Rotator Cuff Deficiencies on Muscle Forces and Glenohumeral Contact Force after Anatomic Total Shoulder Arthroplasty Using Musculoskeletal Multibody Dynamics Simulation[J].Frontiers in Bioengineering and Biotechnology Biomechanics, 2021. (SCI: Accept)
[36] Zhang Qida, Chen Zhenxian, Jin Zhongmin, Muratoglu Orhun, Varadarajan Karti.Patient-specific musculoskeletal models as a framework for comparing ACL function in unicompartmental vs. bicruciate retaining arthroplasty. 2021.(SCI:Accept)
[35] 杨抒, 崔文,张小刚, 张亚丽,任旭辉, 陈瑱贤, 靳忠民. 国内全髋关节置换磨损测试及数值模拟研究进展[J]. 摩擦学学报, 2021.
[34] 崔文, 杨抒, 张小刚, 张亚丽, 张静, 张骁, 陈瑱贤, 靳忠民. 国内全膝关节置换磨损测试及数值模拟研究进展[J]. 中华骨科杂志, 2021.
[33] Weijian Lin, Qingen Meng , Junyan Li , Zhenxian Chen* and Zhongmin Jin. The effect of highly inhomogeneous poroelastic properties on mechanical behaviour of articular cartilage. Computer Methods and Programs in Biomedicine. 2021. (SCI:Accept)
[32]Zhang Yanwei, Chen Zhenxian, Peng Yinghu, et al. Predicting ground reaction and tibiotalar contact forces after total ankle arthroplasty during walking. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 2020.234(12):1432-1444. (SCI:OT0QZ)
[31] Zhang Qida, Chen Zhenxian, Zhang Zhifeng, et al. Leveraging subject-specific musculoskeletal modeling to assess effect of anterior cruciate ligament retaining total knee arthroplasty during walking gait. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 2020: 234(12):1445-1456. (SCI:OT0QZ)
[30] Gao YongChang, Zhao Xuan, Chen ShiBin, Zhang Jing, Chen Zhenxian, Jin Zhongmin. Effects of Daily Activities and Position on Kinematics and Contact Mechanics of Dual Mobility Hip Implant. Journal of healthcare engineering. 2020; 2020: 12.(SCI:KY1QY)
[29] Yinghu Peng, Duo Wai-Chi Wong, Yan Wang, Tony Lin-Wei Chen, Qitao Tan, Zhenxian Chen, Zhongmin Jin, Ming Zhang. Immediate Effects of Medially Posted Insoles on Lower Limb Joint Contact Forces in Adult Acquired Flatfoot: A Pilot Study. Int J Environ Res Public Health. 2020; 17. (SCI: LK3LI)
[28] 张静，陈瑱贤，高永昌，张烜，靳忠民. 膝关节二次运动学研究进展[J]. 中华骨科杂志, 2019, 39(18): 1157-1164.
[27] Zhang Yanwei, Chen Zhenxian*, Zhao Hongmou, Liang Xiaojun, Sun Cheng, Jin Zhongmin. Musculoskeletal modeling of total ankle arthroplasty using force-dependent kinematics for predicting in vivo joint mechanics [J].Proceedings of the Institution of Mechanical Engineers Part H, Journal of engineering in medicine. 2019. (SCI: KE3QQ).
[26] 彭迎虎,陈瑱贤,胡家渝,张志峰,靳忠民,尉萍萍.人体足地接触模型的步速适用性[J].医用生物力学,2019,34(5):514-521
[25]Zhang Jing, ChenZhenxian,Gao Yongchang, Zhang Xuan ,Guo Lei ,Jin Zhongmin .Computational wear prediction for impact of kinematics boundary conditions on wear of total knee replacement using two cross-shear models[J]. Journal of Tribology.2019.(SCI:KC0SN).
[24] 范勋健, 陈瑱贤, 曹卓, 夏志辉, 陈军, 靳忠民. 个体化骨肌多体动力学和有限元联合建模的肩胛骨锁定板生物力学评估方法 [J]. 西安交通大学学报. 2019. 53(07): p. 168-176.
[23]Chen Zhenxian, Zhang jing, et al.Effects of interference assembly of a tibial 1nsert on the tibiofemoral contact mechanics in total knee replacement. Proc Inst Mech Eng H, 2019. 233(9): 948-953. (SCI:IM0DE)
[22] Zhang, Z.F., Zhang, Q. D., Zhao, G. H., Huang, J., Chen, Zhenxian.et al., Morphological Measurements of the Normal Distal Femur and Proximal Tibia between Han Chinese and Mongolian Chinese in a Healthy Chinese Population. International Journal of Morphology, 2019. 37(2): p. 664-670. (SCI: HW9BA)
[21]Liu Xiaoyu, Chen Zhenxian*,Gao Yongchang, et al. High Tibial Osteotomy: Review of techniques and biomechanics.Journal of Healthcare Engineering. 2019. (SCI:IF9MX)
[20]. Zhang Qida, Chen Zhenxian*,Zhang Jing, et al. 1nsert conformity variation affects kinematics and wear performance of total knee replacements.Clinical Biomechanics.2019;65:19-25.(SCI:IB3UF)
[19].Ardestani M. M., Chen ZhenXian, et al. Computational analysis of knee joint stability following total knee arthroplasty[J]. J Biomech, 2019. 10.1016/j.jbiomech.2019.01.029 (SCI:HR0ER)
[18].Hu Jiayu, Xin Hua, Chen Zhenxianet al. The role of menisci in knee contact mechanics and secondary kinematics during human walking[J]. Clinical biomechanics (Bristol, Avon), 2018, 61: 58-63. (SCI:HO1ZY)
[17].Chen Zhenxian, Gao Yongchang, et al. Biomechanics and wear comparison between mechanical and kinematic alignments in total knee arthroplasty[J]. Proc Inst Mech Eng H, 2018: 232(12): 1209–1218(SCI: HE7HN)
[16].Hu Jiayu; Chen Zhenxian*; Xin Hua; Zhang Qida; Jin Zhongmin. Musculoskeletal multibody dynamics simulation of the contact mechanics and kinematics of a natural knee joint during a walking cycle[J]. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine.2018. 232(5):508~519 (SCI:GH0LK)
[15].Gao Yongchang, Chen Zhenxian, et al. Effect of inclination and anteversion angles on kinematics and contact mechanics of dual mobility hip implants[J]. Clin Biomech (Bristol, Avon), 2018, 57: 48-55. (SCI:GP3TG)
[14].Peng Yinghu, Zhang Zhifeng, Gao Yongchang,Chen Zhenxian*,et al. Concurrent prediction of ground reaction forces and moments and tibiofemoral contact forces during walking using musculoskeletal modelling[J].Medical Engineering and Physics, 2018. 52: 31~40. (SCI:GC1BB)
[13].Chen Shibin, Ma Jingcun, Yao Yunshi, Gao Yongchang, Chen Zhenxian, Ping Lin. Investigation of combining dipole antennas with three dimensional photonic crystals[J]. Journal of Physics: Conference Series, 2018, 1053: 012082. 10.1088/1742-6596/1053/1/012082 (SCI)
[12].Zhang Jing, Chen Zhenxian*, Wang Ling, Li Dichen, Jin Zhongmin. A patient-specific wear prediction framework for an artificial knee joint with coupled musculoskeletal multibody-dynamics and finite element analysis[J]. Tribology International, 2017, 109: 382-389. (SCI: EM9DM)
[11].Zhang Jing, Chen Zhenxian*, Wang Ling, et al. Load application for the contact mechanics analysis and wear prediction of total knee replacement[J]. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 2017, 231:444-454. (SCI:ET3RX)
[10].Fan Xunjian, Chen Zhenxian*, Jin Zhongmin, et al. Parametric study of patient-specific femoral locking plates based on a combined musculoskeletal multibody dynamics and finite element modeling[J]. Proceedings of the Institution of Mechanical Engineers Part H, Journal of engineering in medicine, 2017. 232(2):114~126. (SCI:FV2KB)
[9].Chen Zhenxian, Zhang Zhifeng, Wang Ling, et al. Evaluation of a Subject-Specific Musculoskeletal Modeling Framework to Predict Load in Total Knee Arthroplasty[J]. Medical Engineering & Physics, 2016.38(8): 708–716(SCI:DR7KV )
[8].Chen Zhenxian, Wang Ling, Liu Yaxiong, et al. Effect of Component Mal-rotation on the Knee Loading in Total Knee Arthroplasty using Multi-body Dynamics Modelling Under a Simulated Walking Gait[J]. Journal of Orthopaedic Research, 2015, 33(9): 1287–1296. (SCI:CO60E)
[7].Chen Zhenxian^*, Jin Zhongmin. Prediction of In-vivo Kinematics and Contact Track of Total Knee Arthroplasty during Walking[J]. Biosurface and Biotribology, 2016, 2:86-94.
[6].陈瑱贤,王玲,李涤尘,靳忠民. 全膝关节置换的个体化患者右转步态的骨肌多体动力学仿真[J]. 医用生物力学, 2015, 30(5).
[5].Zhang Xuan, Chen Zhenxian, Wang L, et al. Prediction of hip joint load and translation using musculoskeletal modelling with force-dependent kinematics and experimental validation[J]. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 2015. 229(7):477-490. (SCI:CL9LI)
[4].Chen Zhenxian, Zhang Xuan, Ardestani MM, et al. Prediction of in vivo joint mechanics of an artificial knee implant using rigid multi-body dynamics with elastic contacts[J]. Proceedings of the Institution of Mechanical Engineers Part H, Journal of engineering in medicine, 2014, 228:564–575. (SCI:AJ9NA)
[3].Ardestani MM, Chen Zhenxian, Wang L, et al. Feed forward artificial neural network to predict contact force at medial knee joint: Application to gait modification[J]. Neurocomputing, 2014, 139: 114-29.(SCI:AJ4QV)
[2].Ardestani MM, Chen Zhenxian, Wang L, et al. A neural network approach for determining gait modifications to reduce the contact force in knee joint implant[J]. Medical Engineering & Physics. 2014, 36: 1253-65.(SCI:AR5ML)
[1].Ardestani MM, Chen Zhenxian, et al. A real-time topography of maximum contact pressure distribution at medial tibiofemoral knee implant during gait: Application to knee rehabilitation[J]. Neurocomputing, 2014,154:174–188. (SCI:CC1DR)


1. 国家医药行业标准YY/T1426.1-2016/ISO14243-1:2009《中华人民共和国医药行业标准—外科植入物全膝关节假体的磨损—第1部分：载荷控制的磨损试验机的载荷和位移参数及相关的试验环境条件》[S]。(主要起草人：张述，董双鹏，李立宾，王玲，陈瑱贤)。
2.Chen zhenxian, zhang jing, Zhang xiao, Jin zhongmin. Chapter 7 Biomechanics and Tribology of Artificial Knee Joint (In book: UHMWPE Biomaterials for Joint Implants)[M]. Springer Science+Business Media Singapore. 2019:191-240.
3. Jin Zhongmin,Li Junyan, Chen Zhenxian. Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System[M]. Elsevier Ltd. 2020.




科技成果



荣誉奖励



工作经历
2016.08-至今，长安大学