郭媛
ename
Yuan GUO
gender
女
studentNo
employeeNo
**
idNo
610423**4
birth
1979-11-16
partyTime
1998-11-01
officeRoom
823
phone
**
email
guoyuan@nwu.edu.cn
political
中共党员
college
化学与材料科学学院,
collegeName
department
cardNo
nation
汉
placeOfDomicile
陕西西安
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state
在职
researchInterests
分子探针与生物分子示踪
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idNoEndDatetime
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passportEndDatetime
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resume
郭媛，女，1979年11月生，西北大学化学与材料科学学院教授、博士生导师，主讲化学学科本科《有机化学》、研究生《化学生物学》等课程。兼任法国国立奥尔良大学特邀教授、陕西高校新型智库化工助剂与新材料发展研究中心学术委员会委员、《精细化工》杂志编委、Chinese Chemical Letters杂志青年编委。先后主持国家自然科学基金青年面上项目（4项）、国家自然科学基金重点项目（合作，本人负责1/2）等纵向科研项目十余项。以通讯作者/第一作者在Angew. Chem. Int. Ed.、Chem. Sci.、Anal. Chem.等国际知名学术刊物上发表SCI论文40余篇，获授权国家发明专利10项。荣获西北大学第八届青年教师讲课比赛一等奖（2009）、西北大学化学与材料科学学院讲课比赛特等奖（2015）。作为主要完成人，荣获陕西省科学技术一等奖（2005）、三等奖（2010）。入选陕西省“****”科学基金（2020），荣获西安青年科技人才奖（2016）。近三年研究论文：18. Gao Ying; Hu Yulu; Liu Qimeng; Li Xiaokang; Li Xinming; Kim Chu-Young; James Tony D.; Li Jian*; Chen Xi*; Guo Yuan*; Two‐Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence. Angewandte Chemie International Edition, 2021, 60, 10756.17. Wu Ying; Zhang Yanhui; Chen Xi; Hu Yulu; Dong Guoqiang; Guo Yuan*; Sheng Chunquan*; A theranostic probe of indoleamine 2,3-dioxygenase 1 (IDO1) for small molecule cancer immunotherapy. European Journal of Medicinal Chemistry, 2021, 213, 113163.16. Tang Haoyang; Qiang Xinyu; Gao Ying; Teng Hao*; Chen Xi; Zhang Yanhui; Tian Jingye; Qin Bo; Guo Yuan*; Real-time tracking and dual-mode imaging of hypochlorous acid in vivo by a small-sized fluorescence probe. Dyes and Pigments, 2021, 188, 109219.15. Li Xiaokang; Qiu Wenjing; Li Jinwen; Chen Xi; Hu Yulu; Gao Ying; Shi Donglei; Li Xinming; Lin Huiling; Hu Zela; Dong Guoqiang; Sheng Chunquan; Jiang Bei; Xia Conglong; Kim Chu-Young; Guo Yuan*; Li Jian*; First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated β-galactosidase. Chemical Science, 2020, 11, 7292-7301. (Front cover)14. Shi Donglei; Hu Linghao; Li Xinming; Liu Wenwen; Gao Ying; Li Xiaokang; Jiang Bei; Xia Conglong; Guo Yuan*; Li Jian*; Lysosomal polarity increases with aging as revealed by a lysosome-targetable near-infrared fluorescent probe. Sensors and Actuators B: Chemical, 2020, 319: 128302.13. Teng Hao; Tian Jingye; Sun Donghuan; Xiu Mengxue; Zhang Yanhui; Qiang Xingyu; Tang Haoyang*; Guo Yuan*; A mitochondria-specific fluorescent probe based on triazolopyridine formation for visualizing endogenous hypochlorous acid in living cells and zebrafish. Sensors and Actuators B: Chemical, 2020, 319: 128288.12. Zhang Yanhui; Teng Hao; Gao Ying; Afzal Muhammad Wasim; Tian Jingye; Chen Xi; Tang Haoyang; James Tony D.; Guo Yuan*; A general strategy for selective detection of hypochlorous acid based on triazolopyridine formation. Chinese Chemical Letters, 2020, 31: 2917-2920. (Front cover)11. Hu Linghao; Shi Donglei; Li Xinming; Zhu Jin; Mao Fei; Li Xiaokang; Xia Conglong; Jiang Bei; Guo Yuan*; Li Jian*; Curcumin-based polarity fluorescent probes: Design strategy and biological applications. Dyes and Pigments, 2020, 177: 108320.10. Shi Donglei; Chen Shuqiang; Dong Biao; Zhang Yanhui; Sheng Chunquan; James Tony D.; Guo Yuan*; Evaluation of HOCl-generating anticancer agents by an ultrasensitive dual-mode fluorescent probe. Chemical Science, 2019, 10: 3715-3722. (Back cover)9. Li Jin; Yin Xinchi; Li Bin; Li Xiaokang; Pan Yuanjiang; Li Jian; Guo Yuan*; Spiropyran in situ switching: A real-time fluorescence strategy for tracking DNA G-quadruplexes in live cells. Analytical Chemistry, 2019, 91: 5354-5361. 8. Liu Qimeng; Li Anyang; Li Xiaokang; Li Bin; Zhang Yanhui; Li Jian; Guo Yuan*; Selective visualization of live-cell mitochondrial thiophenols and their induced oxidative stress process by a rationally designed rhodol-based fluorescent probe. Sensors and Actuators B: Chemical, 2019, 283: 820-830.7. Li Jin; Gao Ying; Guo Haoran; Li Xiaokang; Tang Haoyang; Li Jian; Guo Yuan*; A novel colorimetric and ratiometric fluorescent probe for selective detection of bisulfite in real samples and living cells. Dyes and Pigments, 2019, 163: 285-290.6. Li Jin; Li Xiaokang; Jia Jianbo; Chen Xi; Lv Yinjuan; Guo Yuan*; Li Jian*; A ratiometric near-infrared fluorescence strategy based on spiropyran in situ switching for tracking dynamic changes of live-cell lysosomal pH. Dyes and Pigments, 2019, 166: 433-442.5. Liu Qimeng; Wang Huan; Guo Haoran; Guo Yuan*; A highly selective coumarin-based fluorescent probe for detecting Fe3+ in pure water systems and living cells. Chinese Journal of Inorganic Chemistry, 2019, 35: 923-929.4. Wang Huan; Shi Donglei; Li Jin; Tang Haoyang; Li Jian; Guo Yuan*; A facile fluorescent probe with a large Stokes shift for sequentially detecting copper and sulfide in 100% aqueous solution and imaging them in living cells. Sensors and Actuators B: Chemical, 2018, 256: 600-608.3. Tang Haoyang; Gao Ying; Li Bin; Li Changwei; Guo Yuan*; Reaction-based colorimetric and ratiometric fluorescent probe for highly selective detection of silver ions. Sensors and Actuators B: Chemical, 2018, 270: 562-569.2. Zhang Yanhui; Ma Lin; Tang Chunchao; Pan Shengnan; Shi Donglei; Wang Shaojing; Li Minyong*; Guo Yuan*; A highly sensitive and rapidly responding fluorescent probe based on a rhodol fluorophore for imaging endogenous hypochlorite in living mice. Journal of Materials Chemistry B, 2018, 6: 725-731. (Front cover)1. Wang Shaojing; Li Jin; Gao Ying; Guo Yuan*; Highly selective and sensitive 2-(2’-hydroxyphenyl) benzothiazole-based turn-on fluorescent probes for detecting and imaging bisulfite in living cells. Asian Journal of Organic Chemistry, 2018, 7: 563-569.
landline
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nativePlace
陕西"