Li, Ke1,2
; Li, Xiao-Ming1; Gloer, James B.3; Wang, Bin-Gui1,2,4发表期刊ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
ISSN2211-9264
2021-06-01
卷号56页码:5
关键词Marine red algaRhodomela confervoidesUreidobromophenolsAntioxidant activity
DOI10.1016/j.algal.2021.102312
通讯作者Li, Ke(kli@yic.ac.cn); Wang, Bin-Gui(wangbg@ms.qdio.ac.cn)
英文摘要An extensive investigation on the chemical components with potential antioxidant activity resulted in the characterization of four new ureidobromophenols (1-4) and two related metabolites (5 and 6) from ethyl acetate extract of the marine red alga Rhodomela confervoides. Their structures were determined using spectroscopic analysis and comparisons with known compounds. Compound 1 possesses unique structure of an ureido group bearing gamma-butyric acid and 2,3-dibromo-4,5-dihydroxybenzyl moieties on the same nitrogen atom. Compounds 1-4 displayed significant antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals with IC50 values ranging from 3.34 to 4.84 mu M, which are more active than that of the positive controls ascorbic acid (IC50 = 20.1 mu M) and butylated hydroxytoluene (IC50 = 82.1 mu M). These compounds also exhibited potent activity against 2,2' -azino-bis(3-ethylbenzothiazoline-6-sulphonate (ABTS) radicals with trolox equivalent antioxidant capacity (TEAC) values ranging from 3.25 to 5.01 mM, which are 3- to 5-fold potent than that of ascorbic acid (TEAC = 1.02 mM). The antioxidant activity of ureidobromophenols isolated from marine alga might boost the seaweed functional food ingredients or dietary food supplements in food industry.
资助机构Natural Science Foundation of China; Shuangbai Plan of Yantai Municipal City; Taishan Scholar Project from Shandong Province of China
收录类别SCI
语种英语
关键词[WOS]INDUCED OXIDATIVE STRESS; FUNCTIONAL FOODS; IN-VITRO; BROMOPHENOLS; FRACTIONS; CAPACITY; EXTRACT
研究领域[WOS]Biotechnology & Applied Microbiology
WOS记录号WOS:000663410100019
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/29431
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者Li, Ke; Wang, Bin-Gui作者单位1.Chinese Acad Sci, Qingdao Natl Lab Marine Sci & Technol, Inst Oceanol,Lab Marine Biol & Biotechnol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
3.Univ Iowa, Dept Chem, Iowa City, IA 52242 USA
4.Chinese Acad Sci, Ctr Ocean Mega Sci, Nanhai Rd 7, Qingdao 266071, Peoples R China
推荐引用方式
GB/T 7714Li, Ke,Li, Xiao-Ming,Gloer, James B.,et al. Naturally occurring ureidobromophenols with potent antioxidant activities from the marine red alga Rhodomela confervoides[J]. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS,2021,56:5.
APALi, Ke,Li, Xiao-Ming,Gloer, James B.,&Wang, Bin-Gui.(2021).Naturally occurring ureidobromophenols with potent antioxidant activities from the marine red alga Rhodomela confervoides.ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS,56,5.
MLALi, Ke,et al."Naturally occurring ureidobromophenols with potent antioxidant activities from the marine red alga Rhodomela confervoides".ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 56(2021):5.
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