Li, Xiao-Dong1,2; Li, Xin1,3,4; Li, Xiao-Ming1,3,4; Yin, Xiu-Li2
; Wang, Bin-Gui1,3,4发表期刊NATURAL PRODUCT RESEARCH
ISSN1478-6419
2019-11-28
页码7
关键词Aspergillus versicolordeep-sea sediment-derived fungusbisabolene-type sesquiterpenoidsantimicrobial activity
DOI10.1080/14786419.2019.1696792
通讯作者Wang, Bin-Gui(wangbg@ms.qdio.ac.cn)
英文摘要One new aromatic bisabolene-type sesquiterpenoid (1), along with four known analogues (2-5) were isolated and identified from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330. Their structures were elucidated by NMR, HRESIMS, X-ray crystallographic analysis, and quantum chemical ECD calculations as well as comparison of those data with literature data. Compounds 1-5 were evaluated for antimicrobial activities against human and aquatic pathogenic bacteria. Compounds 1, 2 and 5 exhibited selective inhibitory activities against zoonotic pathogenic bacteria such as Aeromonas hydrophilia, Escherichia coli, Edwardsiella tarda and Vibrio harveyi, with the MIC values ranging from 1.0 to 8.0 mu g/mL.
资助机构Aoshan Scientific and Technological Innovation Project of Qingdao National Laboratory for Marine Science and Technology; National Natural Science Foundation of China; Key Research and Development Program of Shandong Province; China Postdoctoral Science Foundation; Research Vessel KEXUE of the National Major Science and Technology Infrastructure from the Chinese Academy of Sciences; Taishan Scholar Project from Shandong Province; Shandong Provincial Natural Science Foundation
收录类别SCI
语种英语
关键词[WOS]ENDOPHYTIC FUNGUS; A-D; DERIVATIVES; ANTIFUNGAL; ALKALOIDS; ACID
研究领域[WOS]Chemistry; Pharmacology & Pharmacy
WOS记录号WOS:000501477400001
引用统计被引频次：6[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/28985
专题海岸带生物学与生物资源利用重点实验室
通讯作者Wang, Bin-Gui作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Shandong, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Shandong, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China
4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao, Shandong, Peoples R China
推荐引用方式
GB/T 7714Li, Xiao-Dong,Li, Xin,Li, Xiao-Ming,et al. Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330[J]. NATURAL PRODUCT RESEARCH,2019:7.
APALi, Xiao-Dong,Li, Xin,Li, Xiao-Ming,Yin, Xiu-Li,&Wang, Bin-Gui.(2019).Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330.NATURAL PRODUCT RESEARCH,7.
MLALi, Xiao-Dong,et al."Antimicrobial bisabolane-type sesquiterpenoids from the deep-sea sediment-derived fungus Aspergillus versicolor SD-330".NATURAL PRODUCT RESEARCH (2019):7.
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