其他题名Hoye, Thomas R.; Li, Weiming
Li K(李可)1
; Brant, Cory O.1; Huertas, Mar1,5; Hessler, Edward J.2; Mezei, Gellert3; Scott, Anne M.1; Hoye, Thomas R.4; Li, Weiming1发表期刊Proceedings of the National Academy of Sciences of United States of America
ISSN0027-8424
2018
卷号115期号:34页码:8603-8608
关键词Chemical EcologyAnadromous MigrationOlfactionAnimal BehaviorAgnatha
DOI10.1073/pnas.1803169115
作者部门Fisheries and Wildlife
英文摘要Olfactory cues provide critical information for spatial orientation of fish, especially in the context of anadromous migrations. Born in freshwater, juveniles of anadromous fish descend to the ocean where they grow into adults before migrating back into freshwater to spawn. The reproductive migrants, therefore, are under selective pressures to locate streams optimal for offspring survival. Many anadromous fish use olfactory cues to orient toward suitable streams. However, no behaviorally active compounds have been identified as migratory cues. Extensive studies have shown that the migratory adult sea lampreys (Petromyzon marinus), a jawless fish, track a pheromone emitted by their stream-dwelling larvae, and, consequently, enter streams with abundant larvae. We fractionated extracts of larval sea lamprey washings with guidance from a bioassay that measures in-stream migratory behaviors of adults and identified four dihydroxylated tetrahydrofuran fatty acids, of which (+)-(2S, 3S, 5R)-tetrahydro-3-hydroxy-5-[(1R)-1-hydroxyhexyl]-2-furanoctanoic acid was shown as a migratory pheromone. The chemical structure was elucidated by spectroscopies and confirmed by chemical synthesis and X-ray crystallography. The four fatty acids were isomer-specific and enantiomer-specific in their olfactory and behavioral activities. A synthetic copy of the identified pheromone was a potent stimulant of the adult olfactory epithelium, and, at 5 x 10(-13) M, replicated the extracts of larval washings in biasing adults into a tributary stream. Our results reveal a pheromone that bridges two distinct life stages and guides orientation over a large space that spans two different habitats. The identified molecule may be useful for control of the sea lamprey.
文章类型Article
收录类别SCI
语种英语
关键词[WOS]Laurentian Great-lakes; Petromyzon-marinus L.; Unique Bile-acids; Anadromous Fishes; Odor; Identification; Water; Tetrahydrofurandiols; Lepidoptera; Management
研究领域[WOS]Multidisciplinary Sciences
WOS记录号WOS:000442351000055
引用统计被引频次：18[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24107
专题个人在本单位外知识产出
通讯作者Hoye, Thomas R.; Li, Weiming作者单位1.Michigan State University
2.Bridge Organ Co
3.Western Michigan Univ
4.Univ Minnesota, Dept Chem
5.Texas State Univ
推荐引用方式
GB/T 7714Li K,Brant, Cory O.,Huertas, Mar,et al. A fatty acid derivative acts as a sea lamprey migratory pheromone[J]. Proceedings of the National Academy of Sciences of United States of America,2018,115(34):8603-8608.
APALi K.,Brant, Cory O..,Huertas, Mar.,Hessler, Edward J..,Mezei, Gellert.,...&Li, Weiming.(2018).A fatty acid derivative acts as a sea lamprey migratory pheromone.Proceedings of the National Academy of Sciences of United States of America,115(34),8603-8608.
MLALi K,et al."A fatty acid derivative acts as a sea lamprey migratory pheromone".Proceedings of the National Academy of Sciences of United States of America 115.34(2018):8603-8608.
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