张玉森
张玉森
Yusen Zhang received the PhD degree in computational mathematics from Dalian University of Technology, China, in 2003. He is a professor in School of mathematics and statistics from the Shandong University at Weihai, China. During 2004-2006, He was a postdoctoral fellow in Bioinformatics and Computer Applications at Graduate University of Chinese Academy of Science. His research is in the algorithms in computational biology, bioinformatics and statistical genetics.
联系方式
Affiliation: School of Mathematics and Statistics, Shandong University at Weihai.
Address: 180 wenhua xilu,Weihai, P.R.China 264209
Postcode: 264209
Fax: 86-
Email: zhangys@sdu.edu.cn, yusenzhang@126.com
学术经历
Jan.2008- Professor of School of Mathematics and Statistics, Shandong University at Weihai , China .
Sep.2002-Dec.2007 Associate professor of School of Mathematics and Statistics, Shandong University at Weihai , China .
Mar.2004-Mar.2006 Post doctorate of Bioinformatics and Computer Applications, Graduate University of Chinese Academy of Science .

行政职务与学术兼职


? 2016年开始任山东省物理学会生物物理专业委员会副主任
? 2017年开始任山东省医学影像学研究会精准医学与转化医学分会副主任。
? 数学评论（Mathematical Reviews/MathSciNet） 评论员 (评论员号为087698)。
? 国际SCI杂志MATCH Communications in Mathematical and in Computer Chemistry（影响因子3.58）编委。
? 国际杂志 IJEI: International Journal of Engineering and Industries 编委。
? 国际杂志International Journal of Bioinformatics & Biological Systems (IJBBS)编委
? 国际杂志Mathematics and Computer Science(MCS)编委
? 国际杂志 Current Updates in Bioinformatics编委

访问经历
2013.01-2014.01， Visiting scholar at Washington University in St. Louis.



学习经历
Education and Research

Jan.2008- Professor of School of Mathematics and Statistics, Shandong University at Weihai , China .
Sep.2000-Jun.2003 Doctor of Computational Mathematics, Dalian University of Technology , China .
Sep.1986-Mar.1989 Master of Computational Mathematics, Dalian University of Technology , China .
Sep.1982-Jun.1986 Schoolof Mathematics, Jilin Normal University , China .

项目
Project
1.Research on identification algorithm of cancer-driving pathways based on multi-omics data, Natural Science Foundation of China,2019.01-2022.12.
2.Algorithm of tumor gene expression data analysis and application, Natural Science Foundation of China ,2012-2015.
3.Inversion representation of protein sequence and study on cancer related genes, Shandong Natural Science Foundation, 2010-2013.
4.Analysis of protein sequence and finding the characteristic genes in avian influenza virus genome, Shandong Natural Science Foundation, 2006-2009.
5.Research on application of mathematical method in RNA secondary structure, China Postdoctoral Science Foundation, 2005-2006.
6.Analysis and Implementation of mathematical model in MRI, Natural Science Foundation of ShandongUniversity, 2004-2006.
7.Application of inversion techniques to basic hypergeometric series, Natural Science Foundation of ShandongUniversity, 2002-2004.
8.Mathematical Mechanization Method of combinatorial inversion formulas and Applications, Natural Science Foundation of ShandongUniversity, 2002-2003.
9.Research on identification algorithm of cancer-driving pathways based on multi-omics data (**), Natural Science Foundation of China 2019.01- 2022.12.
10.Study on Intelligent Sensor System for Marine Algae Growth Environment and Its Analytical Techniques (U**), NSFC-Shandong Joint Fund Project 2019.01- 2022.12.


获奖
1. 2011年获山东大学优秀硕士学位论文指导教师荣誉称号
2. 2011年评为山东大学威海分校第二届优秀研究生导师
3. 指导学生在全国大学生数学建模比赛中若干国家二等奖，省一等奖和二等奖。

论著
Ivan Gutman ,Yusen Zhang, Matthias Dehmer, Aleksandar Ilic, Altenburg, Wiener, and Hosoya Polynomials,
book： I. Gutman, B. Furtula (Eds.),Distance in Molecular Graphs Theory, Univ. Kragujevac, Kragujevac, 2012, pp. 49–70.
2019年：
[66] Shenghui Liu; Chunrui Xu; Yusen Zhang; Jiaguo Liu; Bin Yu; Xiaoping Liu; Matthias Dehmer, Feature Selection of Gene Expression Data for Cancer Classification Using Double RBF-kernels, BMC Bioinformatics, 2018, 19:396. (SCI, 通信作者)
[65]M. Kong, Y. Zhang, W. Chen, APGC: Universal Protein Prediction Based on Compositional, Physico-Chemical and Structural Information, MATCH Commun. Math. Comput. Chem. 81 (2019) 000-000 (SCI, IF=2.58, 通信作者)
[64] Matthias dehmer; Zengqiang Chen; Frank Emmert-Streib; Abbe Mowshowitz; Yongtang Shi; Shailesh Tripathi; Yusen Zhang, Towards Detecting Structural Branching and Cyclicity in Graphs: A Polynomial-based Approach, Information Sciences, 471, January 2019, 19-28 (IF 4.832).
[63]Li Ge, Jiaguo Liu, Yusen Zhang , Matthias Dehmer, Identifying Anticancer Peptides by Using a Generalized Chaos Game Representation, Journal of Mathematical Biology, https://doi.org/10.1007/s00285-018-1279-x (SCI, IF=1.786)
2018年：
[62] Chuanyan Wu, Rui Gao, Daoliang Zhang, Shiyun Han, Yusen Zhang, PRWHMDA: Human Microbe-Disease Association Prediction by Random Walk on the Heterogeneous Network with PSO, Int. J. Biol. Sci. 2018; 14(8): 849-857. doi:10.7150/ijbs.24539 (SCI, IF 3.873)
[61]Bin Yu, Shan Li, Wenying Qiu, Minghui Wang, Junwei Du, Yusen Zhang and Xing Chen, Prediction of subcellular location of apoptosis proteins by incorporating PsePSSM and DCCA coefficient based on LFDA dimensionality reduction, BMC Genomics (2018) 19:478.
[60]Lili Cui, Li Ge, Hongbin Gan, Xiaoping Liu, Yusen Zhang (2018) Ovarian Cancer Identification Based on Feature Weighting for High-Throughput Mass Spectrometry Data. Journal of Systems Biology - 1(1):1-11. ，通信作者
[59] Chuanyan Wu, Rui Gao, Yang De Marinis, Yusen Zhang, A novel model for protein sequence similarity analysis based on spectral radius. Journal of Theoretical Biology 446 (2018) 61-70. June 2018

2017年：
[59] Chunrui Xu, Li Ge, Yusen Zhang, Matthias Dehmer, Ivan Gutman, Computational prediction of therapeutic peptides based on graph index, Journal of Biomedical Informatics [58] Zheng-Wei Li , pengyong han , Xiao Li , Yusen Zhang , Haiquan Yu , Ru Nie , Xing Chen , In silico prediction of drug-target interaction networks based on drug chemical structure and protein sequences, Scientific Reports 7, 11174 (2017)
[57] Bin Yu, Lifeng Lou, Shan Li , Yusen Zhang, Wenying Qiua, Xue Wu, Minghui Wang, Baoguang Tian, Prediction of protein structural class for low-similarity sequences using Chou's pseudo amino acid composition and wavelet denoising, Journal of Molecular Graphics and Modelling 76 (2017) 260–273 . July 2017 [56] Lulu Yu, Yusen Zhang, Ivan Gutman, Yongtang Shi, Matthias Dehmer , Protein Sequence Comparison Based on Physicochemical Properties and the Position-Feature Energy Matrix, Sci. Rep. 7, 46237 (2017); doi: 10.1038/srep46237 (2017).
[55] Yu, L., Zhang, Y., Jian, G. Gutman, I., Classification for microarray data based on K-means clustering combined with modified single-to-noise-ratio based on graph energy, J. Comput. Theor. Nanosci. 14, 598–606 (2017). 2016年：

[54] Huihui Chen, Yusen Zhang, Ivan Gutman, A Kernel-Based Clustering Method for Gene Selection with Gene Expression Data, Journal of Biomedical Informatics,2016,62:12-20.
[53] Dandan Sun, Chunrui Xua, Yusen Zhang, Novel Method of 2D Graphical Representation for Proteins and Its Application，MATCH Commun. Math. Comput. Chem. 75 (2016) 431-446. (SCI, IF 3.858)
2015年：
[52 ] Haiyan Wu, Yusen Zhang, Wei Chen, Zengchao Mu, Comparative analysis of protein primary sequences with graph energy, Physica A 437 (2015) 249–262
2014年：
[51 ] Wu J, Zhang Y, Mu Z (2014) Predicting Nucleosome Positioning Based on Geometrically Transformed Tsallis Entropy. PLoS ONE 9(11): e109395.
[50] Yan Su, Yusen Zhang, Wei Chen, Ivan Gutman, Nucleosome Positioning Based on Information Content, MATCH Commun. Math. Comput. Chem. 72(2014), 867-878.
[49] Cangzhi Jia, Yusen Zhang, Zhiping Wang, SulfoTyrP: a high accuracy predictor of protein sulfotyrosine sites, MATCH Commun.Math. Comput. Chem. 71 (2014), 227-240
2013年：
[48] Zengchao Mu, Jing Wu, Yusen Zhang, A novel method for similarity/ dissimilarity analysis of protein sequences，Physica A, 392 (2013) 6361–6366.
[47] Yan XR, Yang YH, Zheng XM, Cui JH, Xie X, Li LW, Chen FL, Hua JL, Zhang YS ,Expression of FGF4 mRNA is mediated by mating behaviours in mice, Cell Biochemistry and Function, 2013 Aug; 31(6): 526-31
[46]. Shengli Zhang , Yusen Zhang , Ivan Gutman, Analysis of DNA Sequences Based on the Fuzzy Integral. MATCH. 2013. 70(1): 417-430. (SCI, IF=2.161)
2012年：SCI 7 篇 共 31 SCI, .
[45] Jiaguo Liu, Ivan Gutman, Zengchao Mu, Yusen Zhang,，q-Wiener index of some compound trees，Applied Mathematics and Computation, 218 (2012), 9528–9535
[44] Z. Zhang, Y. Zhang, W. Chen, I. Gutman, Y. Li, Prediction of Nucleosome Positioning Using the Dinucleotide Absolute Frequency of DNA Fragment, MATCH Commun. Math. Comput. Chem. 68 (2012), 639-650.
[43] Yusen Zhang, Ivan Gutman, Jiaguo Liu, Zengchao Mu,q-Analog of Wiener Index, MATCH Commun. Math. Comput. Chem. 67 (2012), 347-356.
[42] Guiqian Jian, Yusen Zhang, Panpan Qian, Prediction of Subcellular Localization for Apoptosis Protein: Approached with a Novel Representation and Support Vector Machine, MATCH Commun. Math. Comput. Chem. 67 (2012), 867-878.
[41]W. Chen, Y. Zhang, Comparative Analysis of RNA Molecules, MATCH Commun. Math. Comput. Chem. 67 (2012), 253-268.
[40] Liangyun Ren, Yusen Zhang, Ivan Gutman , Predict the classification of transcription factors by incorporating their binding site properties into a novel mode of Chou’s pseudo amino acid composition, Protein & Peptide Letters, 19(2012), 1170-1176.
[39] Zhiqian Zhang, Yusen Zhang, Ivan Gutman, Predicting Nucleosome Positions in Yeast: Using the Absolute Frequency, J. Biomol Struct Dyn 29(5), 1081-1088 (2012).
2011年：
[38] Xingqin Qi, Qin Wu,Yusen Zhang,Eddie Fuller,and Cun-Quan Zhang, A Novel Model for DNA Sequence Similarity Analysis Based on Graph Theory, Evolutionary Bioinformatics 2011:7 149–158。 IF2.68
[37] Panpan Qian, Yusen Zhang, Guiqian Jian, A novel representation of protein sequences and its application, Journal of Convergence Information Technology, 6(2011), 227-235.
[36] Liu, yanqiu, Yusen Zhang, New Invariant of DNA Sequences Based on a New Matrix Representation, Combinatorial Chemistry & High Throughput Screening, 2011, 14, 61-71。IF2.573
[35] Yusen Zhang, Wei Chen, A New Measure for Similarity Searching in DNA Sequences, MATCH Commun. Math. Comput. Chem. 65 (2011), 477-488.
[34] Yusen Zhang, Wei Chen, A Dissimilarity Measure Based on Free Energy of DNA Nearest-neighbor Interaction, J Biomol Struct Dyn 28 (2011), 557- 565.
2010年
[33] Yusen Zhang, Xiangtian Yu, Analysis of Protein Sequence Similarity, The Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA 2010), 1255-1258。（EI）
[32] Yusen Zhang, Liangyun, Ren, Two Feature Selections for Analysis of Microarray Data, The Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA 2010), 1259-1262. （EI）
[31] Yusen Zhang, Wei Chen, Comparisons of RNA secondary structures based on LZ complexity, MATCH Commun. Math. Comput. Chem. 63 (2010), 513-528
[30] Huiling Wang, Yusen Zhang, A new approach to molecular phylogeny of H5N1 avian influenza viruses in Asia, International Journal of Quantum Chemistry, 110 (2010), 1964–1971 2010年4月。
[29] Liu, yanqiu, Zhang, Yusen, A New Method for Analyzing H5N1 Avian Influenza Virus, Journal of Mathematical Chemistry, 47（3）（2010），1129-1144.
2009年：
[28] W. Chen, Y. Zhang, Comparisons of DNA Sequences Based on Dinucleotide, MATCH Commun. Math. Comput. Chem. 61 (2009), 533-540.
[27] W. Chen, Y. Zhang, Three Distances for Rapid Similarity Analysis of DNA Sequences, MATCH Commun. Math. Comput. Chem. 61 (2009), 781-788.
2008年：
[26] Zhang Yusen, Wang Tianming, Some applications of gasper's bibasic summation formula，Rocky Mountain Journal of Mathematics, 38（2008）703-712。
[25] Yusen Zhang, Wei Chen, A new approach to molecular phylogeny of primate mitochondrial DNA, MATCH Commun. Math. Comput. Chem., 59(2008), 625-634。
[24] Yusen Zhang, Mingshu Tan, Visualization of DNA sequences based on 3DD-Curves, J. Math. Chem. 44 (1) (2008), 206-216。
[23] Yusen Zhang, A simple method to construct the similarity matrices of DNA sequences, MATCH Commun. Math. Comput. Chem. 60 (2008), 313-324。
2007年
[22] Zhang Yu-sen, Liao Bo, On the similarity of DNA sequences based on 3-D graphical representation, 生物数学学报, 22(4)(2007),583-590。
[21] Yusen Zhang, On 3D Graphical Representation of RNA Secondary Structure, MATCH Commun. Math. Comput. Chem., 57 (2007), 157-168。
[20] Yusen Zhang, On 2D Graphical Representation of RNA Secondary Structure, MATCH Commun. Math. Comput. Chem. , 57 (2007), 697-710。
[19] Yusen Zhang, Wei Chen , Analysis of Similarity/Dissimilarity of Long DNA Sequences Based on Three 2DD-Curves, Combinatorial Chemistry & High Throughput Screening, 10 (2007), 231-237
[18] Yusen Zhang, Wei Chen , New Invariant of DNA Sequences, MATCH Commun. Math. Comput. Chem., 58 (2007), 207-218。
[17] Yusen Zhang, Wei Chen, Invariants of DNA Sequences Based on 2DD-Curves, Journal of Theoretical Biology, 242 (2006), 382-388。（被引用次数：17）
[16] Yusen Zhang, Bo Liao，Kequan Ding， On 3DD-Curves of DNA Sequences，MolecularSimulation, 32(1)(2006), 29–34。（引用19）
[15] Zhang Yu-Sen，Chen Wei, Liao Bo，Gong Xin-Bo，A method for obtaining integrable couplings，Commun. Theor. Phys. , 45 (6) ( 2006). 1000-1002。
[14] Bo Liao, Yusen Zhang, Kequan Ding, Tianming Wang, Analysis of similarity/dissimilarity of DNA sequences based on a condensed curve representation, Journal of Molecular Structure: THEOCHEM, 717(2005), 199-203. （引用46）
[13]. Jiaquan Zhan, Bo Liao, Yusen Zhang, Numerical characterization of RNA secondary structure, Internet Electronic Conference of Molecular Design 2004, IECMD 2004, Nov. 23 – Dec. 6。
[12]. Yusen Zhang, Bo Liao, Kequan Ding， On 2D Graphical Representation of DNA Sequence of Nondegeneracy, Chemical Physics Letters，411(2005) , 28-32. （引用24）
[11] Tan Mingshu and Zhang Yusen, A Note on the Bivariate and Trivariate Fibonacci Polynomials, The Southeast Asian Bulletin of Mathematics, 32(2005) 975–990.
[10] ZHANG Yusen, Kequan Ding, Another proof of C. Krattenthaler's matrix inverse, 中科院研究生院学报，23 (2006) 577-580。
[9] ZHANG Yu_feng and ZHANG Yusen, A type of multi-component integrable hierarchy, Chinese Physics, 13(8) (2004) 1183-1186.
[8] 张玉森，陈伟，带参数l的Bailey 引理，山东大学学报工学版 34（4）（2004）35-39。
[7] ZHANG Yusen, Chen Wei, q-Triplicate Inverse Series Relations with Applications to q-series，Rocky Mountain Journal of Mathematics, 35（4）（2005）1407-1427。
[6] 张玉森 RNA 二级结构的最小自由能计算， 2004 中国科学院博士后前沿与交叉学科科学论坛 论文集。
[5] ZHANG Yusen, WANG Tianming, Note on Summation Formulas Derived From an Identity of F. H. Jackson，The Australasian Journal of Combinatorics 28 (2003) 295-304。MR** (2005i:05014).
[4] ZHANG Yusen, TAN Mingshu, Summation formulae including a series, 西南师范大学学报 (自然科学版), 5(2002), 646-651。
[3] ZHANG Yusen, WANG Tian-ming, A Formula Containing Four Independent Bases and Its Applications, 数学研究与评论，23(2 ) (2003) 247-252。
[2] 张玉森，陈伟，两个q-级数恒等式，数学的实践与认识，3 2（4）（2002） 1037-1040
[1] 陈伟，张玉森，几个基本超几何级数公式，数学的实践与认识， 3 2（4）（2002），691-694。



已毕业研究生 （以入学时间为序）
朱新义; 王慧玲; 刘颜秋; 任良云, 菅桂倩, 张志乾; 于祥田, 钱盼盼; 吴晶, 于璐婧, (王超); 吴海燕, 苏岩; 陈辉辉, 李卫红, (崔丽丽); 孙丹丹, 许春蕊; 刘圣辉,于璐璐;
在读研究生（以入学时间为序）
孔萌，张家林；徐达，王麟，陈亚光；徐含笑，郝凯静