苏玲 电 话：** 传 真： E-Mail：suling@sdu.edu.cn

教育背景

起止时间 毕业院校 专业

博士 1996.9-2001.7 浙江大学 植物营养学

本科 1992.9-1996.7 山东大学 生物学

工作经历

2008.9-今 山东大学生命科学学院 讲师

2004.2-2008.8 美国Emory University Winship Cancer Institute

2001.9-2004.2 中国科学技术馆 工程师

科研方向

1.肿瘤细胞转移分子机制

2.抗肿瘤药物作用机制

论文

1. Zhao X, Liu X, Su L*. Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells. J Exp Clin Canc Res 2014, 33:3

2. Liu X¹, Su L¹, Liu X. Loss of CDH1 Up-regulates Epidermal Growth Factor Receptor via Phosphorylation of YBX1 in Non-small Cell Lung Cancer cells. FEBS Lett. 2013;587: 3995-4000.

3. Li T¹, Su L¹, Zhong N, Hao X, Zhong D, Singhal S, Liu X. Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells. Autophagy. 2013; 9(7):1057-1068.

4. Yang L¹, Su L¹, Cao C, Xu L, Zhong D, Xu L, Liu X.The chalcone 2'- hydroxyl -4',5' -dimethoxychalcone activates death receptor 5 pathway and leads to apoptosis in human nonsmall cell lung cancer cells. IUBMB Life. 2013; 65:533-43.

5. Xu L¹, Su L¹, Liu X*. PKCδ regulates death receptor 5 expression induced by PS-341 through ATF4-ATF3/CHOP axis in human lung cancer cells. Mol Cancer Ther. 2012.11:2174-82.

6. Liu G¹, Su L¹ ,Hao X, Zhong N, ZHong D, Singhal S, Liu X*. Salermide Upregulates Death Receptor 5 Expression through the ATF4-ATF3-CHOP Axis and Leads to Apoptosis in Human Cancer Cells. J. Cell. Mol. Med. 2012.16:1618-28. 4.

7. Wang Q, Sun W, Hao X, Li T, Su L*, Liu X*.Down-regulation of cellular FLICE-inhibitory protein (Long Form) contributes to apoptosis induced by Hsp90 inhibition in human lung cancer cells. Cancer Cell Int. 2012.12(1):54. 5.

8. Su L¹, Liu G¹, Hao X¹, Zhong N, ZHong D, Liu X *, Singhal S. Death Receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed- induced apoptosis in human lung cancer cells. Eur.J. Cancer.2011.47(16):2471-8. 7.

9. Wang D¹, Su L¹, Huang D, Zhang H, Shin DM, Chen ZG. Downregulation of E-Cadherin enhances proliferation of head and neck cancer through transcriptional regulation of EGFR. Mol Cancer. 2011.10:116. 8.

奖励

1. 山东大学第六届教学能手，2012年

2. 山东大学青年教师课堂教学比赛二等奖，2012年