高超 电 话：** 传 真： E-Mail：jieerbu@sdu.edu.cn

教育背景

博士 2004.09-2009.12 山东大学 发酵工程

本科 2000.09-2004.06 山东大学 生物技术

工作经历

2009.12-2011.12 上海交通大学 博士后

2012.02- 山东大学 副教授

科研方向

1. 微生物生理与生化

2. 生物催化

3. 合成生物学

主持课题

1. 2013.01-2016.12，新型NAD非依赖性D-乳酸脱氢酶催化机理及应用基础研究，国家自然科学基金面上项目

2. 2012.11-2015.12，2-丁醇工程菌的基因组规模系统代谢育种，国家高技术研究发展计划

3. 2013.01-2015.12，基于芽孢表面展示系统构建乳酸生物传感器，山东省优秀中青年科学家奖励基金

4. 2012.09-2014.12，基于NAD非依赖性乳酸脱氢酶的生物传感器研究，山东大学自主创新基金

5. 2010.06-2011.12，生物催化法高效生产手性2-羟基丁酸，中国博士后科学基金面上项目

6 2011.01-2011.12，洋葱伯克霍尔德菌新型NAD非依赖性L-乳酸脱氢酶研究，中国博士后科学基金特别资助

论文

1. Wang Xiuqing, Lv Min, Zhang Lijie, Li Kun, Gao Chao*, Ma Cuiqing, Xu Ping, Efficient bioconversion of 2,3-butanediol into acetoin using Gluconobacter oxydans DSM 2003, Biotechnol Biofuels, 2013, 6, 155, SCI, IF=6.459

2. Gao Chao¹, Wang Xiuqing, Ma Cuiqing, Xu ping, Production of hydroxypyruvate from glycerate by a novel biotechnological route, Bioresour Technol, 2013, 131, 552-4, SCI, IF=5.172

3. Gao Chao¹, Zhang Lijie, Xie Yingjian, Hu Chunhui, Zhang Yue, Li Lixiang, Wang Yu, Ma Cuiqing, Xu Ping, Production of (3S)-acetoin from diacetyl by using stereoselective NADPH-dependent carbonyl reductase and glucose dehydrogenase, Bioresour Technol, 2013, 137, 111–115, SCI, IF=5.172

4. Gao Chao¹, Hu Chunhui, Zheng Zhaojuan, Ma Cuiqing, Jiang Tianyi, Dou Peipei, Zhang Wen, Che Bin, Wang Yujiao, Lv Min, Xu Ping, Regulation of lactate utilization by the FadR-type regulator LldR in Pseudomonas aeruginosa, J. Bacteriol, 2012, 194, 2687–2692, SCI, IF=3.593

5. Gao Chao¹, Zhang Wen, Huang Yuanli, Ma Cuiqing, Xu Ping , Efficient conversion of 1,2-butanediol to (R)-2-hydroxybutyric acid using whole cells of Gluconobacter oxydans, Bioresour Technol, 2012, 115, SCI, IF=5.172

6. Gao Chao¹, Jiang Tianyi, Dou Peipei, Ma Cuiqing, Li Lixiang, Kong Jian, Xu Ping, NAD-Independent L-lactate dehydrogenase is required for L-lactate utilization in Pseudomonas stutzeri SDM, PLoS ONE, 2012, 7, e36519, SCI, IF=4.244

7. Gao Cha¹, Ma Cuiqing, Xu Ping, Biotechnological routes based on lactic acid production from biomass, Biotechnol Adv, 2011, 29, 930-939, SCI, IF= 11.85

8. Gao Chao¹, Zhang Wen, Ma Cuiqing, Liu Peng, Xu Ping, Kinetic resolution of 2-hydroxybutanoate racemic mixtures by NAD-independent L-lactate dehydrogenase, Bioresour Technol, 2011, 102, 4595-4599, SCI, IF=5.172

9. Gao Chao¹, Xu Xiaoman, Zhang Xifeng, Che Bin, Ma Cuiqing, Qiu Jianhua, Tao Fei, Xu Ping, Chemoenzymatic Synthesis of N-Acetyl-D-Neuraminic Acid from N-Acetyl-D-Glucosamine by Using the Spore Surface-Displayed N-Acetyl-D-Neuraminic Acid Aldolase, Appl Environ Microbiol. 2011, 77, 7080-7083, SCI, IF=4.406

10. Gao Chao¹, Zhang Wen, Lv Chuanjuan, Li Lixiang, Ma Cuiqing, Hu Chunhui, Xu Ping, Efficient production of 2-oxobutyrate from 2-hydroxybutyrate using whole cells of Pseudomonas stutzeri strain SDM. Appl Environ Microbiol, 2010, 76, 1679–1682, SCI, IF= 4.406

专利

1. 一种酶法拆分外消旋乳酸生产D-乳酸的方法、2010.12、ZL**4

2. 耐热的芽孢杆菌及其在制备苯乳酸中的应用、2011.12、ZL **3

3. 一种生产D-α-羟基丁酸的方法、2013.04、ZL **3

4. 一种表达定向进化L-乳酸脱氢酶的工程菌及应用、2013.06、ZL **4