学 历
博士

职 称
教授

所属部门
植物学系

招生专业
发育生物学（博士、硕士）

联系方式
电话:** Email: yhwang@genetics.ac.cn

个人简介

王永红，博士，教授，博士生导师，国家****基金获得者。1991年获北京农学院学士学位，1998年获中国科学院遗传所硕士学位，2004年获中国科学院遗传与发育生物学研究所博士学位。曾于2001年10月至2002年2月在香港科技大学进行访问研究，于2002年5月至2002年11月在英国John Innes Centre进行合作研究。2010年获国家****基金资助，2011年1月入选中国科学院“****”（D类）。2018年入选山东省“一事一议”顶尖人才。2019年起担任山东农业大学教授。担任Faculty Member of F1000、《Frontier in Plant Science》、《Science China Life Sciences》、《Plant Communications》、《aBIOTECH》和《植物学报》等杂志编委。近年来，在高等植物株型调控研究领域取得了一系列原创性研究成果，在Nature、Nature Genetics、Nature Communication、PNAS、Plant Cell等国际主流学术期刊上发表论文50余篇。主持和参加多项973、863、国家重大科学研究计划、国家基金委重大研究计划重点项目等科研项目。

教学工作

中国科学院大学主讲“功能基因组学”课程（2015-2019）和高级分子遗传学，并参加“科学前沿讲座”；在中国科学院遗传与发育生物学研究所、中国农科院研究生院、中国科技大学、首都师范大学等科研院所进行研究生专题课程授课。

研究方向

作物产量性状的遗传调控及其与环境信号的互作机制。主要以水稻和小麦为材料，通过遗传学、生物化学、细胞生物学及组学等手段研究作物株型形成的调控网络，挖掘对产量有贡献且可利用的基因资源用于精准基因编辑和分子设计育种。

科研项目

1.国家自然科学基金委重点项目：SP1介导营养与植物激素协同调控水稻穗分枝发育的分子机理研究（**），2020/01-2024/12，项目负责人。
2.国家自然科学基金委重大研究计划集成项目：水稻产量与品质协同调控的遗传机制（**），2020/01-2021/12，项目负责人。
3.山东省自然科学基金委重大基础研究项目：小麦高产优质抗逆的重要基因挖掘及分子设计育种（ZR2019ZD15），2019/12-2024/12，团队负责人。
4. 山东省“一事一议”科技创新A类：作物株型的分子调控与高产抗逆设计育种（325-72259）， 2019-2022，项目负责人。
5. 中国科学院战略先导科技专项（B类）：水稻分蘖形成的遗传调控网络解析（XDB**），2018/06-2023/05，课题负责人。
6. 中国科学院战略先导科技专项（A类）：水稻株型与抗倒伏的分子模块解析（XDA**），2013/08-2018/07，子课题负责人。
7. 国家自然科学基金委重大研究计划集成项目：水稻株型遗传调控网络解析（**），2017/01-2018/12，项目负责人。
8. 国家自然科学基金委重大研究计划重点支持项目：水稻分蘖角度的遗传调控网络研究（**），2016/01-2017/12，项目负责人。
9. 国家自然科学基金委重大研究计划集成项目：植物激素作用的分子机理（**），2015/01-2015/12，项目负责人。
10. 科技部重大研究计划：侧生生长点干细胞微环境重建的分子基础（2013CB967302），2013/01-2017/12，课题负责人。
11. 科技部重大研究计划：高产性状的分子机制与设计（2013CBA01401），2013/01-2017/12，任务负责人。
12. 国家自然科学基金国际合作项目（中荷）：独脚金内酯在水稻适应磷缺乏过程中的作用（），2011/12-2015/12，项目负责人。
13. 国家自然科学基金创新群体项目：植物生殖发育生物学（**），2010/01-2015/12，任务负责人。
14. 国家自然科学基金****科学基金：植物学（**），2011/01-2014/12，项目负责人。




荣誉称号

作为主要完成人获得2017年国家自然科学一等奖、2005年国家自然科学二等奖、2013年中国科学院杰出成就奖（集体），研究成果入选2014年“中国科学十大进展”。



发表论文

发表论文(^§First author;*Corresponding author. )

通讯作者（含共同）
1.Zhen Li^§, Yan Liang^§, Yundong Yuan, Lei Wang, Xiangbing Meng, Guosheng Xiong, Jie Zhou, Yueyue Cai, Ningpei Han, Lekai Hua, Guifu Liu, Jiayang Li*, andYonghong Wang* (2019) OsBRXL4 regulates shoot gravitropism and rice tiller angle through affecting LAZY1 nuclear localization.Mol Plant. 12:1143-1156.
2. Ning Zhang^§, Hong Yu^§, Hao Yu^§, Yueyue Cai, Linzhou Huang, Cao Xu, Guosheng Xiong, Xiangbing Meng, Jiyao Wang, Haofeng Chen, Guifu Liu, Yanhui Jing, Yundong Yuan, Yan Liang, Shujia Li, Steven M Smith, Jiayang Li, andYonghong Wang*(2018)A core regulatory pathway controlling rice tiller angle mediated by the LAZY1-dependent asymmetric distribution of auxin.Plant Cell. 30: 1461-1475.
3.Jing Wang^§, Hong Yu^§, Guosheng Xiong, Zefu Lu, Yongqing Jiao, Xiangbing Meng, Guifu Liu, Xuewei Chen,Yonghong Wang*, and Jiayang Li* (2017) Tissue-specific ubiquitination by IPA1 INTERACTING PROTEIN 1 modulates IPA1 protein levels to regulate plant architecture in rice.Plant Cell. 29: 697-707.
4.Weiyan Jia^§, Baohua Li^§, Shujia Li^§, Yan Liang, Xiaowei Wu, Mei Ma, Jiyao Wang, Jin Gao, Yueyue Cai, Yuanya Zhang, Yingchun Wang, Jiayang Li*, andYonghong Wang* (2016) Mitogen-activated protein kinase cascade MKK7-MPK6 plays important roles in plant development and regulates shoot branching by phosphorylating PIN1 inArabidopsis.PLOS Biol.14, e**.
5. Di Wu, Linzhou Huang, Jin Gao, andYonghong Wang* (2016) The molecular mechanism of plant gravitropism.Hereditas. 38, 589–602.
6. Yan Liang, andYonghong Wang* (2016) The genes controlling rice architecture and its application in breeding.Chin Bull Life Sci. 28, 1156–1167.
7. Shujia Li, Jin Gao, Jiayang Li, andYonghong Wang* (2015) Advances in regulating rice tillers by strigolactones.Chin Bull Bot.50, 539–548.
8. Dajun Sang^§, Dongqin Chen^§, Guifu Liu, Yan Liang, Linzhou Huang, Xiangbing Meng, Jinfang Chu, Xiaohong Sun, Guojun Dong, Yundong Yuan, Qian Qian, Jiayang Li*, andYonghong Wang* (2014) Strigolactones regulate rice tiller angle by attenuating shoot gravitropism through inhibiting auxin biosynthesis.Proc Natl Acad Sci USA.111, 11199-11204.
9. Liang Jiang^§, Xue Liu^§, Guosheng Xiong^§, Huihui Liu^§, Fulu Chen, Lei Wang, Xiangbing Meng, Guifu Liu, Hong Yu, Yundong Yuan, Wei Yi, Lihua Zhao, Honglei Ma, Yuanzheng He, Zhongshan Wu, Karsten Melcher, Qian Qian, H. Eric Xu*,Yonghong Wang*, and Jiayang Li* (2013) DWARF 53 acts as a repressor of strigolactone signalling in rice.Nature.504, 401-405.
10. Lisheng Chen^§, Guosheng Xiong^§, Xia Cui, Meixian Yan, Ting Xu, Qian Qian, Yongbiao Xue, Jiayang Li, andYonghong Wang* (2013) OsGRAS19 may be a novel component involved in the brassinosteroid signaling pathway in rice.Mol Plant.6, 988-991.
11. Jian Wu, Xue Liu, andYonghong Wang* (2011) Progress of plant functional genomics.Chin Bull Life Sci. 23, 168-178.
12. Fengli Sun, Weiping Zhang, Guosheng Xiong, Meixian Yan, Qian Qian, Jiayang Li, andYonghong Wang* (2010) Identification and functional analysis of the MOC1 interacting protein 1.J Genet Genomics.37, 69-77.
13. Xia Cui^§, Chunmin Ge^§, Renxiao Wang, Huanzhong Wang, Weiqi Chen, Zhiming Fu, Xiangning Jiang, Jiayang Li, andYonghong Wang* (2010) TheBUD2mutation affects plant architecture through altering cytokinin and auxin responses inArabidopsis.Cell Res.20, 576-586.
14. Zhen Li, Guosheng Xiong, andYonghong Wang*. (2010) Auxin actions in regulating plant gravitropism.Chin Bull Life Sci. 22, 15-23.
15. Guosheng Xiong, Jiayang Li, andYonghong Wang* (2009) Advances in the regulation and crosstalks of phytohormones.Chinese Sci Bull.54, 2718–2733.
16. Hao Lin^§, Renxiao Wang^§, Qian Qian^§, Meixian Yan, Xiangbing Meng, Zhiming Fu, Cunyu Yan, Biao Jiang, Zhen Su, Jiayang Li, andYonghong Wang* (2009) DWARF27, an iron-containing protein required for the biosynthesis of strigolactones, regulates rice tiller bud outgrowth.Plant Cell.21, 1512-1525.
17. Shengben Li^§, Qian Qian^§, Zhiming Fu, Dali Zeng, Xiangbing Meng, Junko Kyozuka, Masahiko Maekawa, Xudong Zhu, Jian Zhang, Jiayang Li, andYonghong Wang* (2009)Short panicle1encodes a putative PTR family transporter and determines rice panicle size.Plant J.58, 592-605.
18. Rui Zhang, Bing Wang, Jian Ouyang, Jiayang Li, andYonghong Wang*(2008)Arabidopsisindole synthase, a homolog of tryptophan synthase alpha, is an enzyme involved in the Trp-independent indole-containing metabolite biosynthesis.J Integr Plant Biol.50, 1070-1077.
19. Weihui Xu^§, Juan Huang^§, Baohua Li, Jiayang Li, andYonghong Wang* (2008) Is kinase activity essential for biological functions of BRI1?Cell Res.18, 472-478.
20. Bing Wang, Jiayang Li, andWang Y* (2006) Advances in understanding the roles of auxin involved in modulating plant architecture.Chin Bull Bot. 23, 433–442.
21. Guosheng Xiong^§, Xingming Hu^§, Yongqing Jiao, Yanchun Yu, Chengcai Chu1, Jiayang Li, Qian Qian*, andYonghong Wang* (2006)LEAFY HEAD 2, which encodes a putative RNA-binding protein, regulates shoot development of rice.Cell Res.16, 267-276.
22. Xiaoqun Wang, Weihui Xu, Ligeng Ma, Zhiming Fu, Xingwang Deng, Jiayang Li, andYonghong Wang* (2006) Requirement ofKNAT1/BPfor the development of abscission zones inArabidopsis thaliana.J Integr Plant Biol.48, 15-26.

第一作者（含共同）
1.Cao Xu^§,Yonghong Wang^§, Yanchun Yu^§, Jingbo Duan, Zhigang Liao, Guosheng Xiong, Xiangbing Meng, Guifu Liu, Qian Qian*, and Jiayang Li* (2012) Degradation of MONOCULM 1 by APC/C^TAD1regulates rice tillering.Nat Commun.3, 750.
2.Yonghong Wang, and Jiayang Li* (2011) Branching in rice.Curr Opin Plant Biol.14, 94-99.
3. Yongqing Jiao^§,Yonghong Wang^§, Dawei Xue^§, Jing Wang, Meixian Yan, Guifu Liu, Guojun Dong, Dali Zeng, Zefu Lu, Xudong Zhu, Qian Qian*, and Jiayang Li* (2010) Regulation ofOsSPL14by OsmiR156 defines ideal plant architecture in rice.Nat Genet.42, 541-544.
4.Yonghong Wang,and Jiayang Li* (2008) Molecular basis of plant architecture.Annu Rev Plant Biol.59, 253-279.
5.Yonghong Wang,and Jiayang Li* (2008) Rice, rising.Nat Genet.40, 1273-1275.
6. Peijin Li^§,Yonghong Wang^§, Qian Qian^§, Zhiming Fu, Mei Wang, Dali Zeng, Baohua Li, Xiujie Wang, and Jiayang Li* (2007)LAZY1controls rice shoot gravitropism through regulating polar auxin transport.Cell Res.17, 402-410.
7.Yonghong Wang, Minsheng Chen, and Jiayang Li* (2007) Rice. In Biotechnology in Agriculture and Forestry, Vol. 59 Transgenic Crops IV (ed. By E.C Pua and M.R Davey), Springer-Verlag Berlin Heidelberg. Pp. 35–54.
8.Yonghong Wang,and Jiayang Li* (2006) Genes controlling plant architecture.Curr Opin Biotechnol.17, 123-129.
9.Yonghong Wang,and Jiayang Li* (2005) The plant architecture of rice (Oryza sativa).Plant Mol Biol.59, 75-84.
10.Yonghong Wang,Xiongbiao Xue*,and Jiayang Li*(2005) Towards molecular breeding and improvement of rice in China.Trends Plant Sci.10, 610-614.
11. Yuxin Hu^§,Yonghong Wang^§,Xinfang Liu, and Jiayang Li*(2004)Arabidopsis RAV1is down-regulated by brassinosteroid and may act as a negative regulator during plant development.Cell Res.14, 8-15.

合作论文
1.Jianshu Zheng^§, Kai Hong^§, Longjun Zeng^§, Lei Wang, Shujing Kang, Minghao Qu, Jiarong Dai, Linyuan Zou, Lixin Zhu, Zhanpeng Tang, Xiangbing Meng, Bing Wang, Jiang Hu, Dali Zeng, Yonghui Zhao, Peng Cui, Quan Wang, Qian Qian, Yonghong Wang, Jiayang Li, and Guosheng Xiong*(2020). Karrikin Signaling Acts Parallel to and Additively with Strigolactone Signaling to Regulate Rice Mesocotyl Elongation in Darkness.Plant cell.32, 2780-2805.
2.Lei Wang^§, Qian Xu^§, Hong Yu, Haiyan Ma, Xiaoqiang Li, Jun Yang, Jinfang Chu, Qi Xie, Yonghong Wang, Steven M. Smith, Jiayang Li, Guosheng Xiong*, and Bing Wang*(2020). Strigolactone and Karrikin Signaling Pathways Elicit Ubiquitination and Proteolysis of SMXL2 to Regulate Hypocotyl Elongation in Arabidopsis. Plant cell.32, 2251-2270.
3.Chuyu Ye^§, Wei Tang^§, Dongya Wu^§, Lei Jia, Jie Qiu, Meihong Chen, Lingfeng Mao, Feng Lin, Haiming Xu, Xiaoyue Yu, Yongliang Lu,Yonghong Wang, Kenneth M. Olsen, Michael P. Timko and Longjiang Fan* (2019) Genomic evidence of human selection on Vavilovian mimicry.Nat Ecol Evol. 3:1474-1482.
4.Hengbin Gao, Wenguang Wang,Yonghong Wang, and Yan Liang* (2019) Molecular mechanisms underlying plant architecture and its environmental plasticity in rice.Mol Breeding. 39:167.
5.Xiaoguang Song^§,Zefu Lu^§,Hong Yu^§,Gaoneng Shao,Jinsong Xiong,Xiangbing Meng,Yanhui Jing,Guifu Liu,Guosheng Xiong,Jingbo Duan,Xuefeng Yao,Chunming Liu,Hongqing Li,Yonghong Wang,andJiayang Li^*(2017)IPA1 functions as a downstream transcription factor repressed by D53 in strigolactone signaling in rice.Cell Res.27:1128-1141.
6. Honglei Ma^§, Jingbo Duan^§, Jiyuan Ke^§, Yuanzheng He, Xin Gu, Ting Hai Xu, Hong Yu,Yonghong Wang, Joseph S. Brunzelle, Yi Jiang, Scott B. Rothbart, H. Eric Xu*, Jiayang Li*, and Karsten Melcher* (2017) A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.Sci Adv. 3, e**.
7Wei Xin, Zhicai Wang, Yan Liang,Yonghong Wang, and Yuxin Hu* (2017) Dynamic expression reveals a two-step patterning ofWUSandCLV3during axillary shoot meristem formation inArabidopsis.J Plant Physiol.214:1-6.
8. Dali Zeng^§, Zhixi Tian^§, Yuchun Rao, Guojun Dong, Yaolong Yang, Lichao Huang, Yujia Leng, Jie Xu, Chuan Sun, Guangheng Zhang, Jiang Hu, Li Zhu, Zhenyu Gao, Xingming Hu, Longbiao Guo, Guosheng Xiong,Yonghong Wang, Jiayang Li*, and Qian Qian* (2017) Rational design of high-yield and superior-quality rice.Nat Plants. 3:17031.
9. Bing Wang^§, Jinfang Chu^§, Tianying Yu^§, Qian Xu, Xiaohong Sun, Jia Yuan, Guosheng Xiong, Guodong Wang,Yonghong Wang, and Jiayang Li* (2015) Tryptophan-independent auxin biosynthesis contributes to early embryogenesis inArabidopsis.Proc Natl Acad Sci USA.112, 4821-4826.
10. Jian Wu^§, Yuefeng Sun^§, Yannan Zhao, Jian Zhang, Lilan Luo, Meng Li, Jinlong Wang, Hong Yu, Guifu Liu, Liusha Yang, Guosheng Xiong, Jian-Min Zhou, Jianru Zuo,Yonghong Wang, and Jiayang Li* (2015) Deficient plastidic fatty acid synthesis triggers cell death by modulating mitochondrial reactive oxygen species.Cell Res.25, 621-633.
11. Lei Wang^§, Bing Wang^§, Liang Jiang, Xue Liu, Xilong Li, Zefu Lu, Xiangbing Meng,Yonghong Wang, Steven M. Smith, and Jiayang Li* (2015) Strigolactone signaling inArabidopsisregulates shoot development by targeting D53-Like SMXL repressor proteins for ubiquitination and degradation.Plant Cell.27, 3128-3142.
12. Li-Hua Zhao^§, X Edward Zhou^§, Wei Yi^§, Zhongshan Wu, Yue Liu, Yanyong Kang, Li Hou, Parker W de Waal, Suling Li, Yi Jiang, Adrian Scaffidi, Gavin R Flematti, Steven M Smith, Vinh Q Lam, Patrick R Griffin,Yonghong Wang, Jiayang Li, Karsten Melcher*, and H Eric Xu* (2015) Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3.Cell Res.25, 1219-1236.
13. Yuexing Wang^§, Guosheng Xiong^§, Jiang Hu^§, Liang Jiang, Hong Yu, Jie Xu, Yunxia Fang, Longjun Zeng, Erbo Xu, Jing Xu, Weijun Ye, Xiangbing Meng, Ruifang Liu, Hongqi Chen, Yanhui Jing,Yonghong Wang, Xudong Zhu*, Jiayang Li*, and Qian Qian* (2015) Copy number variation at theGL7locus contributes to grain size diversity in rice.Nat Genet.47, 944-948.
14. Zefu Lu^§, Gaoneng Shao^§, Jinsong Xiong, Yongqing Jiao, Jing Wang, Guifu Liu, Xiangbing Meng, Yan Liang, Guosheng Xiong,Y6nghong Wang, and Jiayang Li* (2015)MONOCULM 3, an ortholog ofWUSCHELin rice, is required for tiller bud formation.J Genet Genomics.42, 71-78.
15. Catarina Cardoso^§, Yanxia Zhang^§, Muhammad Jamil^§, Jo Hepworth^§, Tatsiana Charnikhova, Stanley O. N. Dimkp, Caroline Meharg, Mark H. Wright, Junwei Liu, Xiangbing Meng,Yonghong Wang, Jiayang Li, Susan R. McCouch, Ottoline Leyser, Adam H. Price, Harro J. Bouwmeester*, and Carolien Ruyter-Spira (2014) Natural variation of rice strigolactone biosynthesis is associated with the deletion of twoMAX1orthologs.Proc Natl Acad Sci USA.111, 2379-2384.
16. Li-Hua Zhao^§, X Edward Zhou^§, Zhong-Shan Wu^§, Wei Yi, Yong Xu, Suling Li, Ting-Hai Xu, Yue Liu, Run-Ze Chen, Amanda Kovach, Yangyong Kang, Li Hou, Yuanzheng He, Cen Xie, Wanling Song, Dafang Zhong, Yechun Xu,Yonghong Wang, Jiayang Li, Chenghai Zhang*, Karsten Melcher*and H Eric Xu* (2013) Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.Cell Res.23, 436-439.
17. Zefu Lu^§, Hong Yu^§, Guosheng Xiong^§, Jing Wang, Yongqing Jiao, Guifu Liu,Yanhui Jing, Xiangbing Meng, Xingming Hu, Qian Qian, Xiangdong Fu,Yonghong Wang, and Jiayang Li* (2013) Genome-wide binding analysis of the transcription activator ideal plant architecture1 reveals a complex network regulating rice plant architecture.Plant Cell.25, 3743-3759.
18. Karsten Melcher^§, Ley-Moy Ng^§, X. Edward Zhou^§, Fen-Fen Soon^§, Yong Xu, Kelly M. Suino-Powell, Sang-Youl Park, Joshua J. Weiner, Hiroaki Fujii, Viswanathan Chinnusamy, Amanda Kovach, Jun Li,Yonghong Wang, Jiayang Li, Francis C. Peterson, Davin R. Jensen, Eu-Leong Yong, Brian F. Volkman, Sean R. Cutler, Jian-Kang Zhu, and H. Eric Xu* (2009) A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.Nature.462, 602-608.
19. Zhixi Tian^§, Qian Qian^§, Qiaoquan Liu^§, Meixian Yan, Xinfang Liu, Changjie Yan, Guifu Liu, Zhenyu Gao, Shuzhu Tang, Dali Zeng,Yonghong Wang, Jianming Yu*, Minghong Gu*, and Jiayang Li* (2009) Allelic diversities in rice starch biosynthesis lead to a diverse array of rice eating and cooking qualities.Proc Natl Acad Sci USA.106, 21760-21765.
20. Yanchun Yu^§, Tian Tang^§, Qian Qian^§,Yonghong Wang, Meixian Yan, Dali Zeng, Bin Han, Chung-I Wu*, Suhua Shi*, and Jiayang Li* (2008) Independent losses of function in a polyphenol oxidase in rice: differentiation in grain discoloration between subspecies and the role of positive selection under domestication.Plant Cell.20, 2946-2959.
21. Baisheng Yu^§, Zhongwei Lin^§, Haixia Li, Xiaojiao Li, Jiayang Li,Yonghong Wang, Xia Zhang, Zuofeng Zhu, Wenxue Zhai, Xiangkun Wang, Daoxin Xie, Chuanqing Sun* (2007)TAC1, a major quantitative trait locus controlling tiller angle in rice.Plant J.52, 891-898.
22. Dali Zeng, Meixian Yan,Yonghong Wang, Xinfang Liu, Qian Qian*, and Jiayang Li* (2007)Du1, encoding a novel Prp1 protein, regulates starch biosynthesis through affecting the splicing ofWx^bpre-mRNAs in rice (Oryza sativaL.).Plant Mol Biol.65, 501-509.
23. Chunmin Ge^§, Xia Cui^§,Yonghong Wang, Yuxin Hu, Zhiming Fu, Dongfen Zhang, Zhukuan Cheng, and Jiayang Li* (2006)BUD2, encoding an S-adenosylmethionine decarboxylase, is required forArabidopsisgrowth and development.Cell Res.16, 446-456.