李红岩，女，副教授







学习工作简历：




1993.9-1997.7 烟台大学，生物化学专业，获学士学位




1997.9-2002.7 中国海洋大学，海洋生物学，获博士学位




2002.7-2003.11 中国海洋大学，讲师




2003.11-2007 Université Pierre et Marie Curie, France 博士后




2007-至今 中国海洋大学，讲师，副教授，2011年入选教育部新世纪优秀人才计划







研究方向：发育与进化




目前的研究主要聚焦于模式动物（主要以斑马鱼为研究对象）的组织、器官形成，对体轴形成以及感觉器官(眼睛等)形成中重要基因的表达调控、功能、作用机制以及相关的信号通路进行研究。







在研科研项目：




1 Zfp36l2在胚胎体轴形成中的作用机理研究(**)，2013.01-2016.12 国家自然科学基金面上项目，主持




2 发育与免疫(NCET-11-0469)，2012.01-2014.12，教育部新世纪人才项目，主持




3 对虾白斑综合征爆发的分子基础(2012CB114401)，2012.01-2016.12，973项目，参加




近年来发表论文:




1 Li HY, Grifone R., Saquet A., Carron C., Shi DL. The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins. Development, 2013, 140(24):4903-4913




2 Wu J, Li HY*, Zhang SC. Regulator of complement activation (RCA) group 2 gene cluster in zebrafish: identification, expression, and evolution. Functional & Integrative Genomics. 2012, 12(2):367-77 *通讯作者




3 Ji DR, Liu P, Wang F, Zhang SC, Li HY*. Identification and expression of a novel member of Ly-6 superfamily in zebrafish Denio rerio. Development Genes and Evolution. 2012, 222(2): 119-124 *通讯作者




4 Wang F., Yu Y., Ji DR Li HY*. The DMRT gene family in amphioxus. Journal of Biomolecular Structure and Dynamics 2012, 30(2):191-200. *通讯作者




5 Sun G, Li H*, Wang Y, Zhang B, Zhang S*. Zebrafish complement factor H and its related genes: identification, evolution, and expression. Functional & Integrative Genomics. 2010, 10: 577-587 *通讯作者




6 H.Y. Li, A. Bourdelas, C. Carron, D.L. Shi, The RNA-binding protein Seb4/RBM24 is a direct target of MyoD and is required for myogenesis during Xenopus early development. Mech Dev. 2010, 127(5-6):281-91.




7 Bourdelas#, H.Y. Li#, C. Carron and D.L. Shi Dynamic expression pattern of distinct genes in the presomitic and somitic mesoderm during Xenopus development. Int. J. Dev. Biol. 2009, 53: 1075-1079




8 H.Y. Li, A Bourdelas, C. Carron, C. Gomez, J.C. Boucaut and D.L. Shi, FGF8, Wnt8 and Myf5 are target genes of Tbx6 during anteroposterior specification in xenopus embryo. Developmental Biology 2006, 290(2):470-81.




9 Wang S, Li F, Hu L, Liu S, Li H, Zhang S. Structural and functional characterization of a TGFβ molecule from amphioxus reveals an ancient origin of both immune-enhancing and -inhibitory functions. Dev Comp Immunol. 2014, 45(2):219-226




10 Sun C, Wu J, Liu S, Li H, Zhang S. Zebrafish CD59 has both bacterial-binding and inhibiting activities. Dev Comp Immunol. 2013, 41(2):178-88.




11 Zhang Y, Chen J, Yao F, Ji D, Li H, Zhang S. Expression and functional analysis of properdin in zebrafish Danio rerio. Dev Comp Immunol. 2013, 40(2):123-31.




12 Li F, Li H, Zhang S. Ikaros expression in tongue sole macrophages: a marker for lipopolysaccharide- and lipoteichoic acid-induced inflammatory responses. Mol Biol Rep. 2011, 38(4):2273-9




13 Shao M, Liu ZZ, Wang CD, Li HY, Carron C, Zhang HW, Shi DL. Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent extension in vertebrate embryos. Development 2009, 136(12):2121-31.




14 Zhang S. Wang S. Li H. Li L. Vitellogenin, a multivalent sensor and an antimicrobial effector. Int. j. biochem. cell biol. 2011, 43: 303-305




15 Grandy D, Shan J, Zhang X, Rao S, Akunuru S, Li H, Zhang Y, Alpatov I, Zhang XA, Lang RA, Shi DL, Zheng JJ. Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled. J Biol Chem. 2009, 284(24):16256-63







联系方式：




邮箱：hongyanli@ouc.edu.cn




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