姓名：程晓杰

学历/职称/职务：博士研究生/讲师/硕士研究生导师

联系方式：

邮箱：xjcheng@ouc.edu.cn

电话：+**466

地址：山东省青岛市鱼山路5号（266003）中国海洋大学 海洋生命学院



学习工作简历：

2008.07—至今 中国海洋大学 海洋生命学院 讲师/硕士研究生导师

2005.09—2008.06 中国海洋大学 海洋生物学专业 博士研究生

1997.07—2005.07 青岛市排水管理处 助理工程师/工程师

1994.09—1997.06 青岛海洋大学 海洋生物学专业 硕士研究生

1990.09—1994.07 青岛海洋大学 生态学与环境生物学专业 本科生

科研领域描述：

在山东省高校重点实验室“生物化学与海洋生物材料实验室”从事科研工作。主要研究领域包括：壳聚糖纳米微球载药/载基因技术、壳聚糖水凝胶细胞培养体系构建和医用生物材料开发研究。

代表性成果：

发表论文：

1. Qian Qian Wang, Ming Kong, Yi An, Ya Liu, Jing Jing Li, Xuan Zhou, Chao Feng, Jian Li, Shao Yan Jiang, Xiao Jie Cheng*, Xi Guang. Chen*. Hydroxybutyl chitosan thermo-sensitive hydrogel: a potential drug delivery system. Journal of Materials Science. 2013, 48: 5614–5623 (SCI)

2. Chao Feng, Zhiguo Wang, Changqing Jiang, Ming Kong, Xuan Zhou, Yang Li, Xiaojie Cheng*, Xiguang Chen*. Chitosan/o-carboxymethyl chitosan nanoparticles for efficient and safe oral anticancer drug delivery: In vitro and in vivo evaluation. International Journal of Pharmaceutics, 2013, 457: 158–167 (SCI)

3. Ya Nan Wei, Qian Qian Wang, Ting Ting Gao, Ming Kong, Kui Kun Yang, Yi An, Shao Yan Jiang, Jian Li, Xiao Jie Cheng*, Xi Guang Chen*. 3-D culture of human umbilical vein endothelial cells with reversible thermosensitive hydroxybutyl chitosan hydrogel. Journal of Materials Science - Materials in Medicine. 2013, 24(7): 1781-1787 (SCI)

4. Wei Fang Liu, Hui Di Zang, Xuan Zhou, Chuan Zhen Kang, Yang Li, Jing Li, Qi Feng Dang, Xiao Jie Cheng* & Xi Guang Chen*. The primary culture and subculture of lymphoid cells from shrimp, Penaeus chinensis on thermo-sensitive CS/a, b-GP hydrogel. Aquaculture Research. 2012, 1–7 (SCI)

5. Yang Li, Ming Kong, Chao Feng, Wei Fang Liu, Ya Liu, Xiao Jie Cheng*, Xi Guang Chen*.Preparation and property of layer-by-layer alginate hydrogel beads based on multi-phase emulsion technique. Journal of Sol-Gel Science and Technology. 2012, 62: 217–226 (SCI)

6. Ya Liu, Hui Di Zang, Ming Kong, Fang Kui Ma, Qi Feng Dang, Xiao Jie Cheng?, Qiu Xia Ji, Xi Guang Chen*. In vitro evaluation of mucoadhesion and permeation enhancement of polymeric amphiphilic nanoparticles. Carbohydrate Polymers. 2012, Vol. 89, 453– 460 (SCI)

7. Weifang Liu, Chuanzhen Kang, Ming Kong, Yang Li, Jing Su, Yi An, Xiaojie Cheng*, Xiguang Chen*. Controlled release behaviors of chitosan/α,β-glycerophosphate thermo-sensitive hydrogels. Frontiers of Materials Science in China. 2012, 6(3): 250–258.

8. Jing Li, Ming Kong, Xiao Jie Cheng, Jing Jing Li, Wei Fang Liu, Xi Guang Chen. A facile method for preparing biodegradable chitosan derivatives with low grafting degree of poly(lactic acid). International Journal of Biological Macromolecules. 2011, 49: 1016–1021 (SCI)

9. Qing Sheng Zhao, Qiu Xia Ji, Xiao Jie Cheng, Gang Zheng Sun, Chao Ran, Bing Zhao, Xi Guang Chen*. Preparation of alginate coated chitosan hydrogel beads by thermosensitive internal gelation technique. Journal of Sol-Gel Science and Technology. 2010, 54: 232-237 (SCI)

10. Qing Sheng Zhao, Xiao Jie Cheng, Qiu Xia Ji, Chuan Zhen Kang, Xi Guang Chen*.Effect of organic and inorganic acids on chitosan/glycerophosphate thermosensitive hydrogel. Journal of Sol-Gel Science and Technology. 2009, 50: 111–118 (SCI)

专利：

1. “Process for preparing compounds of chitosan saccharified with aminosugar”，Xiguang Chen, Jing Li, Xiaojie Cheng, Tao Jiang，美国发明专利，授权专利号US 8,202,971 B2，申请人为中国海洋大学，授权日2012年6月19日。

2. “一种壳聚糖羟丁基衍生物的制备方法”，陈西广、李晶晶、程晓杰、王倩倩，国家发明专利，授权专利号ZL**6.X，申请人为中国海洋大学，授权日2012年7月6日。

获奖及荣誉：

1. “海洋生物材料壳聚糖纳米技术研究”， 国家海洋局 海洋创新成果奖 二等奖，陈西广、程晓杰、刘成圣、吉秋霞、刘晨光、孟祥红、于乐军，2010年10月。

2. 中国海洋大学 2011年度 优秀班主任




Curriculum Vitae

Name：Xiaojie Cheng

Title：PhD/Lecturer of Marine Biology/Master Candidate Supervisor

Contact

Email：xjcheng@ouc.edu.cn

Tel：+**466

Address：College of Marine Life Sciences, Ocean University of China,

5 Yushan Road, Qingdao 266003, P. R. China

Experiences:

Education

2005.09—2008.06 Doctor of Science, Ocean University of China

Specialization in Marine Biology

1994.09—1997.06 Master of Science, Ocean University of Qingdao

Specialization in Marine Biology

1990.09—1994.07 Bachelor of Science, Ocean University of Qingdao

Specialization in Ecology and Environmental Biology

Research

2008.07—present Lecture/ Master Candidate Supervisor, Ocean University of China

1997.07—2005.07 Assistant Engineer/Engineer, Qingdao Drainage Administration

Teaching

Molecular Biology, Experimental Methods in Molecular Biology, Environmental Engineering

Research Interests:

Carrying out research works in Key Laboratory of Biochemistry and Marine Biomaterials (Ocean University of China) of Colleges and universities in Shandong Province. Including Drug/DNA/siRNA delivery technique based on chitosan nanoparticles, Construction of Cell culture system with chitosan hydrogel, Development of Biomedical materials.

Achievements:

Publications

1. Qian Qian Wang, Ming Kong, Yi An, Ya Liu, Jing Jing Li, Xuan Zhou, Chao Feng, Jian Li, Shao Yan Jiang, Xiao Jie Cheng*, Xi Guang. Chen*. Hydroxybutyl chitosan thermo-sensitive hydrogel: a potential drug delivery system. Journal of Materials Science. 2013, 48: 5614–5623 (SCI)

2. Chao Feng, Zhiguo Wang, Changqing Jiang, Ming Kong, Xuan Zhou, Yang Li, Xiaojie Cheng*, Xiguang Chen*. Chitosan/o-carboxymethyl chitosan nanoparticles for efficient and safe oral anticancer drug delivery: In vitro and in vivo evaluation. International Journal of Pharmaceutics. 2013, 457: 158–167 (SCI)

3. Ya Nan Wei, Qian Qian Wang, Ting Ting Gao, Ming Kong, Kui Kun Yang, Yi An, Shao Yan Jiang, Jian Li, Xiao Jie Cheng*, Xi Guang Chen*. 3-D culture of human umbilical vein endothelial cells with reversible thermosensitive hydroxybutyl chitosan hydrogel. Journal of Materials Science - Materials in Medicine. 2013, 24(7):1781-1787 (SCI)

4. Wei Fang Liu, Hui Di Zang, Xuan Zhou, Chuan Zhen Kang, Yang Li, Jing Li, Qi Feng Dang, Xiao Jie Cheng* & Xi Guang Chen*. The primary culture and subculture of lymphoid cells from shrimp, Penaeus chinensis on thermo-sensitive CS/a, b-GP hydrogel. Aquaculture Research. 2012, 1–7 (SCI)

5. Yang Li, Ming Kong, Chao Feng, Wei Fang Liu, Ya Liu, Xiao Jie Cheng*, Xi Guang Chen*.Preparation and property of layer-by-layer alginate hydrogel beads based on multi-phase emulsion technique. Journal of Sol-Gel Science and Technology. 2012, 62: 217–226 (SCI)

6. Ya Liu, Hui Di Zang, Ming Kong, Fang Kui Ma, Qi Feng Dang, Xiao Jie Cheng?, Qiu Xia Ji, Xi Guang Chen*. In vitro evaluation of mucoadhesion and permeation enhancement of polymeric amphiphilic nanoparticles. Carbohydrate Polymers. 2012, 89: 453– 460 (SCI)

7. Weifang Liu, Chuanzhen Kang, Ming Kong, Yang Li, Jing Su, Yi An, Xiaojie Cheng*, Xiguang Chen*. Controlled release behaviors of chitosan/α,β-glycerophosphate thermo- sensitive hydrogels. Frontiers of Materials Science in China. 2012, 6(3): 250–258

8. Jing Li, Ming Kong, Xiao Jie Cheng, Jing Jing Li, Wei Fang Liu, Xi Guang Chen. A facile method for preparing biodegradable chitosan derivatives with low grafting degree of poly (lactic acid). International Journal of Biological Macromolecules. 2011, 49: 1016–1021 (SCI)

9. Qing Sheng Zhao, Qiu Xia Ji, Xiao Jie Cheng, Gang Zheng Sun, Chao Ran, Bing Zhao, Xi Guang Chen*. Preparation of alginate coated chitosan hydrogel beads by thermosensitive internal gelation technique. Journal of Sol-Gel Science and Technology. 2010, 54: 232-237 (SCI)

10. Qing Sheng Zhao, Xiao Jie Cheng, Qiu Xia Ji, Chuan Zhen Kang, Xi Guang Chen*. Effect of organic and inorganic acids on chitosan/glycerophosphate thermosensitive hydrogel. Journal of Sol-Gel Science and Technology. 2009, 50: 111–118 (SCI)

Patents

1. “Process for preparing compounds of chitosan saccharified with aminosugar”, Inventors: Xiguang Chen, Jing Li, Xiaojie Cheng & Tao Jiang. United State Patent, Patent No.: US 8,202,971 B2. Assignee: Ocean University of China. Date of Patent: Jun. 19, 2012.

2. “Process for preparing Hydroxybutyl chitosan”, Inventors: Xiguang Chen, Jingjing Li, Xiaojie Cheng & Qianqian Wang. China Patent, Patent No.: ZL**6.X. Assignee: Ocean University of China. Date of Patent: Jul. 6, 2012.

Awards & Honors

1. “Research on nanotechinques of Marine biomaterial chitosan”, The second Prize of Marine Innovation Achievement Award, National Bureau of Oceanography. Xiguang Chen, Xiaojie Cheng, Chengsheng Liu, Qiuxia Ji, Chenguang Liu, Xianghong Meng & Lejun Yu. Oct., 2010.

2. Excellent class teacher in 2011, Ocean University of China