陈淼鑫 副主任医师，副教授
硕士招生类型：学术型；专业型
硕士招生专业：妇产科学
博士招生类型：专业型
博士招生专业：妇产科学
所在院系：附属第一妇幼保健院
联系方式：miaoxinchen@hotmail.com
课题组链接：
研究方向
主要任职
科研业绩

辅助生殖技术对胚胎及子代健康的影响及其机制 Effects of assisted reproductive technologies on embryos and offspring and its mechanisms
上海市科委专家库成员；上海市第三届生殖医学会青年委员会副主任委员；第一届海峡两岸医药卫生交流协会遗传与生殖专业委员会青年委员
2010.10-2016.1在澳大利亚阿德莱德大学做博士及博士后研究，期间博士论文被评为研究生院优秀论文；目前主持科研项目5项，参与两项国家重点研发计划；参加国际性学术会议10次，大会报告6次，墙报介绍4次；发表文章36篇，其中SCI文章15篇，第一作者SCI文章10篇(总影响因子31.4）；担任5个SCI期刊的审稿人: Scientific Reports (影响因子3.9），Biology of Reproduction (影响因子3.3），Reproductive Biology and Endocrinology (影响因子3.2），Reproductive Sciences (影响因子2.6）及Obesity Research & Clinical Practice (影响因子2.1）。
I completed my PhD and postdoctoral research at the University of Adelaide in Australia from Oct 2010 to Jan 2016, and my thesis was awarded the Dean’s Commendation for Doctoral Thesis Excellence of the University of Adelaide in 2014. Currently I am undertaking five research projects. I have attended international conferences on ten occasions, in which I delivered six oral presentations and four poster presentations. I have published 36 papers, 15 of which were included in SCI journals, and I was the first author in 10 papers (total impact factor 31.4). I am a registered reviewer for the SCI journals, Scientific Reports (impact factor 3.9), Biology of Reproduction (impact factor 3.3), Reproductive Biology and Endocrinology (impact factor 3.2), Reproductive Sciences (impact factor 2.6) and Obesity Research & Clinical Practice (impact factor 2.1).
主持科研课题5项:
1.2019年度上海市科委医学引导类（中、西医）科技支撑项目（项目批准号：**；直接费用：20万元）；
2.2018年度中华医学会临床医学科研专项资金生殖医学青年医师研究与发展项目（项目批准号：**；直接费用：11万元）；
3.2018年国家自然科学基金委面上项目（项目批准号：**；直接费用：57万元）；
4.2016年国家自然科学基金委面上项目（项目批准号：**；直接费用：57万元）；
5.2016年上海市卫计委计划生育类项目（项目批准号：；资助经费：10万元）。
参与科研课题2项:
1.国家重点研发计划子课题人类子宫内膜的形成机制（项目编号：SQ2017ZY050118-03） ；
2.国家重点研发计划人类配子发生成熟障碍的分型（项目编号：2016YFC**）
Publications (First authors):
1.Miaoxin Chen*, Yuanyuan Wu*, Xin Huang*, et al. Embryo incubation by time-lapse systems versus conventional incubators in Chinese women with diminished ovarian reserve undergoing IVF/ICSI: a study protocol for a randomized controlled trial. BMJ Open. (Impact factor 2.5) (Accepted)；
2.Miaoxin Chen, Xin Huang, Yiping Liu, et al. Systematic oxidative stress is not associated with live birth rate in young non-obese patients with polycystic ovarian syndrome undergoing assisted reproduction cycles：A prospective cohort study. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2020 Oct; 253:154-161. (Impact factor 1.8)；
3.Xin Huang*, Bi Wu*, Miaoxin Chen*, Ling Hong, et al. Depletion of exosomal circLDLR in follicle fluid derepresses miR-1294 function and inhibits estradiol production via CYP19A1 in polycystic ovary syndrome. Aging-US. 2020 Jul 10;12(15):15414-15435.（Impact factor 4.8）；
4.Miaoxin Chen, Siew Wong, Linda Wu, et al. Differential impacts of gonadotropins, in vitro fertilization and mouse embryo culture on blastocyst development. Reproductive biomedicine online. 2019 Mar; 39: 372–382.（Impact factor 2.9）；
5.Miaoxin Chen, Leonie Heilbronn. The health outcomes of human offspring conceived by assisted reproductive technologies (ART). Journal of Developmental Origins of Health and Disease. 2017 Aug;8(4):388-402.（Impact factor 1.7）；
6.Miaoxin Chen, Linda Wu, Junli Zhao, et al. Altered glucose metabolism in mice and humans conceived by in-vitro fertilization (IVF). Diabetes. 2014 Oct; 63(10): 3189-98.（Impact factor 8.5）；
7.Miaoxin Chen, Anne Macpherson, Julie Owens, et al. Obesity alone or with type 2 diabetes is associated with tissue specific alterations in DNA methylation and gene expression of PPARGC1A and IGF2. Journal of Diabetes Research & Clinical Metabolism 2012; 2012:1；
8.Miaoxin Chen, Robert Norman, Leonie Heilbronn. Does in vitro fertilisation increase type 2 diabetes and cardiovascular risk? Current Diabetes Review. 2011;7(6):426-32；
9Miaoxin Chen, Zhuhua Yuan, Keren Shan. Association of Apo lipoprotein J Gene 866C→T Polymorphism with Preeclampsia and Essential Hypertension. Gynecology Obstetric Investigation 2005; 60:133-138（Impact factor 1.1）