摘要/Abstract

摘要： 肌少-骨质疏松症是骨质疏松症和肌少症并存的一种老年综合征，在老年人群中广泛存在。骨质疏松症是以骨量降低、骨组织微结构破坏为特点的骨骼疾病；肌少症是指全身肌量减少、肌强度下降或肌肉生理功能的减退。肌少症和骨质疏松症是与年龄相关的退行性疾病，具有相似的病理生理基础，包括机械因素、遗传学、脂肪浸润和内分泌因素等。研究肌少-骨质疏松症的发病机制对预防和治疗该疾病，提高老年人生活质量和身心健康有重要的意义。该文就肌少-骨质疏松症的诊断、发病机制、干预及治疗进行综述。
关键词: 肌少-骨质疏松症, 肌少症, 骨质疏松症, 发病机制, 治疗
Abstract:
Osreosarcopenia is a geriatric syndrome that describes the co-existence of osteoporosis and sarcopenia, which is widespread in the elderly. Osteoporosis is a condition of low bone mass and micro-architectural of bone, and sarcopenia, the loss of muscle mass, strength and muscle physiological functions. Sarcopenia and osteoporosis are age-related degenerative diseases with similar pathophysiology, including mechanical factors, genetics, fatty infiltration and endocrine factors. Studying the pathogenesis of sarcopenia-osteoporosis is of great significance in preventing and treating the disease, improving the quality of life and physical and mental health of the elderly. This review introduces the diagnosis, pathogenesis, intervention and treatment of osteosarcopenia.
Key words: osteosarcopenia, sarcopenia, osteoporosis, pathogenesis, therapeutic


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