摘要/Abstract
摘要： 目的 ·了解孕妇对无创产前检测技术的认知程度、态度、意愿和需求。方法 ·选择上海交通大学医学院附属新华医院 318名血清学唐氏综合征筛查低风险孕妇及 534 名在上海多家医院经血清学唐氏综合征筛查发现为高风险并前往上海交通大学医学院附属新华医院无创产前检测门诊的孕妇作为研究对象。就 852名孕妇对无创产前检测技术的认知程度、态度、意愿和需求进行问卷调查。结果 ·回收问卷 760份，其中有效问卷共 728份，有效问卷率为 85.45%。孕妇对无创产前检测的认知达标率仅为 51.24%，但 83.10%的孕妇对无创产前检测的推广持积极态度。79.54%的孕妇认为在无创产前检测前提供的遗传咨询非常必要。结论 ·加强产前健康宣传教育、做好无创产前检测前的遗传咨询，可提高孕妇的认知程度，有助于合理利用无创产前检测。
关键词: 无创产前检测, 产前筛查, 产前诊断, 孕妇
Abstract:
Objective · To understand the cognition, attitude, willingness and demand for non-invasive prenatal testing (NIPT) of pregnant women. Methods · A total of 852 pregnant women were enrolled, including 318 pregnant women with low risk of Down syndrome screened in Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, and 534 pregnant women with high risk of Down syndrome screened in several hospitals in Shanghai who further went to Xinhua Hospital, Shanghai Jiao Tong University School of Medicine for NIPT to confirm the diagnosis of Down syndrome screening. The information about the cognition, attitude, willingness and demand for NIPT was collecteda standard questionnaire. Results · A total of 760 questionnaires were collected, of which 728 ones were valid, with an effective questionnaire rate of 85.45%. The proportion of pregnant women with ideal cognition level was 51.24%. However, 83.10% of pregnant women held a positive attitude towards the promotion of NIPT. There were 79.54% of pregnant women considering it necessary to provide genetic counseling before NIPT. Conclusion · It is of great significance to strengthen the prenatal propaganda and education and pre-test genetic counseling so as to improve the cognitive level of pregnant women and make rational of NIPT.
Key words: non-invasive prenatal testing (NIPT), prenatal screening, prenatal diagnosis, pregnant women
PDF全文下载地址:
点我下载PDF
