摘要/Abstract

摘要： 菌毛作为细菌表面附属物，在宿主细胞黏附和细菌生物被膜形成中发挥关键的作用。该文主要介绍有关沙门菌非典型菌毛 Saf结构和功能的最新研究，并揭示 Saf 菌毛介导的生物被膜形成机制，为靶向生物被膜相关的细菌耐药提供新思路。
关键词: Saf 菌毛, 宿主识别, 生物被膜
Abstract:
As appendages surfacing on bacterium, pili play key roles in host cell adhesion and biofilm formation. The present paper introduces the latest
structural and functional studies of Salmonella atypical pili Saf and uncovers the mechanism of Saf pili driven biofilm formation, which provides new
strategy to target bacterial biofilm related antibiotic resistance.
Key words: Saf pili, host recognition, biofilm formation


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