进入90年代，我国药学科学的发展战略转变为以新药研究与开发为中心，使得药物代谢与药物动力学研究已成为药学科学非常活跃的前沿领域之一。本课程主要讲授药物的吸收、分布、代谢与排泄等方面的内容与最新进展。将系统阐述药物代谢与药物动力学的基本理论及其在新药研究中的应用，包括吸收分布的新理论，药物代谢反应的类型与特点、药物代谢反应的立体选择性、转运蛋白在药物吸收代谢中的作用，影响药物代谢的因素、药物代谢与新药开发及其各类药物在人体内的代谢途径及意义；这些药物在体内的分析方法及新技术等。

The major topics included in this course are: mathematical and physiologic principles of pharmacokinetics related to the development and use of pharmaceutical dosage forms. This will include the discussion of compartmental modeling, physiological concepts of pharmacokinetics, metabolism and clearance and absorption concepts. The overall objective of this course is for students to acquire a working knowledge and understanding of drug disposition ,metabolism including basic kinetic principles and the impact of dosge form design on drug absorption behavior.