导师姓名： 赵旭赟 专业代码： 100100
性别： 男 专业名称： 基础医学
培养单位： 基础医学院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师：
联系方式： 上海市重庆南路280号7号楼115
邮编： 200025 邮箱地址： zhaobig_8888@hotmail.com

研究方向 (点击浏览详细信息)
RNA生物学与代谢稳态

社会任职

科研项目

学术论文 作者论文标题期刊名出版年卷期页码
Zhao XY （通讯作者）, Li S, Ji Y, Peng X, Qi L, Lin JD The obesity-induced adipokine sST2 exacerbates adipose Treg and ILC2 depletion and promotes insulin resistance Sci Adv 2020 6(20):eaay6191
Liu T, Mi L, Xiong J, Orchard P, Yu Q, Yu L, Zhao XY, Meng ZX, Parker SCJ, Lin JD, Li S. BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning Nat Commun 2020 11(1):2379
Zhao XY, Li S, DelProposto JL, Liu T, Mi L, Porsche C, Peng X, Lumeng CN, Lin JD The long noncoding RNA Blnc1 orchestrates homeostatic adipose tissue remodeling to preserve metabolic health Mol Metab 2018 14:60-70
Zhao XY, Xiong X, Liu T, Mi L, Peng X, Rui C, Guo L, Li S, Lin JD. Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis. Nat Commun 2018 9(1):2986
Chen Z, Wang GX, Ma SL, Jung DY, Ha H, Altamimi T, Zhao XY, Guo L, Zhang P, Hu CR, Cheng JX, Lopaschuk GD, Kim JK, Lin JD. Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders Mol Metab 2017 6(8):863-872
Li S, Mi L, Yu L, Yu Q, Liu T, Wang GX, Zhao XY, Wu J, Lin JD. Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis Proc Natl Acad Sci USA 2017 114(34):E7111-E7120
Mi L, Zhao XY, Li S, Yang G, Lin JD. Conserved function of the long noncoding RNA Blnc1 in brown adipocyte differentiation. Mol Metab 2016 6(1):101-110
Wang GX, Zhao XY, Lin JD The brown fat secretome: metabolic functions beyond thermogenesis. Trends Endocrinol Metab 2015 26(5):231-237
Shen SM, Guo M, Xiong Z, Yu Y, Zhao XY, Zhang FF, Chen GQ. AIF inhibits tumor metastasis by protecting PTEN from oxidation. EMBO Rep 2015 16(11):1563-80
Zhao XY, Lin JD Long Noncoding RNAs: A New Regulatory Code in Metabolic Control Trends Biochem Sci 2015 40:586-596
Wang GX, Zhao XY （共同第一作者）, Meng ZX, Kern M, Dietrich A, Chen Z, Cozacov Z, Zhou D, Okunade AL, Su X, Li S, Blüher M, Lin JD The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuating hepatic lipogenesis. Nat Med 2014 20(12):1436-43
Zhao XY, Li S, Wang GX, Yu Q, Lin JD A long noncoding RNA transcriptional regulatory circuit drives thermogenic adipocyte differentiation Mol Cell 2014 55(3):372-82
Liu W, Shen SM, Zhao XY, Chen GQ Targeted genes and interacting proteins of hypoxia inducible factor-1 Int J Biochem Mol Biol 2012 3(2):165-78
Huang Y, Hou JK, Chen TT, Zhao XY, Yan ZW, Zhang J, Yang J, Kogan SC, Chen GQ PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway. Autophagy 2011 7(10):1132-44
Zhao XY （共同第一作者）, Zhao KW, Jiang Y, Zhao M, Chen GQ Synergistic induction of galectin-1 by CCAAT/enhancer binding protein-? and hypoxia inducible factor-1? and its role in differentiation of acute myeloid leukemic cells. J Biol Chem 2011 286(42):36808-19
Zhao XY （共同第一作者）, Chen TT, Xia L, Guo M, Xu Y, Yue F, Jiang Y, Chen GQ, Zhao KW. Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells Carcinogenesis 2010 31(8): 1367-75
Zhao M, Duan XF, Zhao XY, Zhang B, Lu Y, Liu W, Cheng JK, Chen GQ Protein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cells PloS One 2009 4(8):e6552
Liao SH, Zhao XY （共同第一作者）, Han YH, Zhang J, Wang LS, Xia L, Zhao KW, Zheng Y, Guo M, Chen GQ Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells Proteomics 2009 9(15):3901-12