导师姓名： 钟捷 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属瑞金医院 三级学科/
专业领域： 消化系病
导师类型： 博士生导师 专业学位导师： 兼
联系方式：
邮编： 邮箱地址： jimmyzj64@medmail.com.cn

研究方向 (点击浏览详细信息)
炎症性肠病

社会任职
中华医学会全国小肠疾病学组委员
中国癌症协会（CSCO）胃肠道间质瘤学组委员
中华医学会消化道肿瘤协作组（小肠肿瘤组）成员
中华医学会全国消化内镜学会委员
上海炎症性肠病学组副组长
上海消化内镜学会小肠镜学组副组长
中华医学会消化病协会炎症性肠病学组委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 血小板P2RY12介导Sin1-mTORC2/Akt通路促进IBD进展的机制研究 国家自然科学基金 2020-01~2023-12 57万元 课题负责人
** Vimentin及其磷酸化修饰促进克罗恩病发生发展的机制研究 国家自然科学基金 2017-01~2020-12 58万元 课题负责人
ZHYY-ZXYJHZX-201608 清肠栓联合水杨酸制剂SASP在溃疡性直肠炎诱导及维持缓解的疗效评价 上海市综合医院中西医结合专项项目 2016-12~2018-12 10万元 课题负责人
** 基于不同部位及基因突变特征的胃肠道间质瘤临床诊治方案的优化 上海市科委医学重点项目 2013-06~2016-09 30万元 课题负责人
制定小肠检查新技术(胶囊内镜、单或双气囊小肠镜、CT小肠重建)在炎症性肠病应用的规范 卫生行业科研专项项目 2011-09~2013-12 0万元 子课题负责人
溃疡性结肠炎癌变风险及监测 卫生行业科研专项项目 2011-09~2013-12 0万元 子课题负责人
英夫利昔单抗早期干预治疗中国汉族克罗恩病患者的疗效及对其肠粘膜修复影响 横向项目 2011-06~2014-12 5万元 课题负责人
舒尼替尼治疗分化良好的晚期胰腺NET的疗效及安全性评价 吴阶平癌症基金项目 2011-06~2014-12 5万元 课题负责人
** 小肠GIST的规范性诊断流程的探索 上海市卫生局,局级课题 2008-01~2009-12 3万元
08YZ44 小肠间质瘤基因突变与预后的关系研究及分子标记物探索 上海市教委,发展基金 2008-01~2010-12 8万元

学术论文 作者论文标题期刊名出版年卷期页码
Juntao Sun,Tianyu Zhang,Mengmeng Cheng,Liwen Hong,Mengfan Xie,Peijun Sun,Rong Fan,Zhengting Wang,Lei Wang,Zhong Jie （通讯作者） TRIM29 facilitates the epithelial-to-mesenchymal transition and the progression of colorectal cancer via the activation of the Wnt/β-catenin signaling pathway Journal of Experimental & clinical Cancer Research 2019 38(104):1-15
Maochen Zhang,Tianyu Zhang,Liwen Hong,Chen Zhang,Jie Zhou,Rong Fan,Lei Wang,Zhengting Wang,Bin Xu, Jie Zhong （通讯作者） Improvement of psychological status after infliximab treatment in patients with newly diagnosed Crohn’s disease Patient Preference and Adherence 2018 12:879-885
Liwen Hong, Tianyu Zhang , Yun Lin, Rong Fan,Maochen Zhang,Mengmeng Cheng, Xiaolin Zhou , Juntao Sun, Peijun Sun, Qiangqiang Wu,Lei Wang, Zhengting Wang,Jie Zhong （通讯作者） Prognostic Analysis of Duodenal Gastrointestinal Stromal Tumors Gastroenterology Research and Practice 2018 2018：1-7
Maochen Zhang,Tianyu Zhang,Liwen Hong,Qiangqiang Wu,Yun Lin,Mengfan Xie,Rong Fan,Zhengting Wang,Jie Zhou,Jie Zhong （通讯作者） Comparison of patients’tolerance between computed tomography enterography and double-balloon enteroscopy Patient Preference and Adherence 2017 11:1755-1766
Maochen Zhang,Liwen Hong,Tianyu Zhang,Yun Lin,Sichang Zheng,Xiaolin Zhou,Rong Fan,Zhengting Wang,Chenli Zhang, Jie Zhong （通讯作者） Illness perceptions and stress: mediators between disease severity and psychological well-being and quality of life among patients with Crohn’s disease Patient Preference and Adherence 2016 10:2387-2396
Shurong Hu, Mengmeng Chen, Yilin Wang, Zhengting Wang, Yaofei Pei,Rong Fan, Xiqiang Liu, Lei Wang, Jie Zhou, Sichang Zheng, Tianyu Zhang,Yun Lin, Maochen Zhang, Ran Tao, Jie Zhong （通讯作者） mTOR Inhibition Attenuates Dextran Sulfate Sodium-Induced Colitis by Suppressing T Cell Proliferation and Balancing TH1/TH17/Treg Profile Plos One 2016 2016：1-19
Tianyu Zhang, ZhengtingWang, Rong Fan, Maochen Zhang, Yun Lin, Liwen Hong, Xiaolin Zhou, Shurong Hu, Mengmeng Cheng, Jie Zhong （通讯作者） The Efficacy of Infliximab Monotherapy versus Infliximab-Azathioprine Sequential Treatment in Crohn’s Disease: Experience from a Tertiary Medical Center in China BioMed Research International 2016 2016:1-6
Tian-Yu Zhang, Yun Lin, Rong Fan, Shu-Rong Hu, Meng-Meng Cheng, Mao-Chen Zhang, Li-Wen Hong,Xiao-Lin Zhou, Zheng-Ting Wang, Jie Zhong （通讯作者） Potential model for differential diagnosis between Crohn's disease and primary intestinal lymphoma World Journal of Gastroenterol 2016 22（42）：9411-9418
Fan R, Zhong J （通讯作者）, Zheng S, Wang Z, Xu Y, Li S, Zhou J, Yuan F. microRNA-218 increase the sensitivity of gastrointestinal stromal tumor to imatinib through PI3K/AKT pathway. Clin Exp Med. 2015 15(2):137-44.
Wang Z, Xu B, Zhang H, Fan R, Zhou J, Zhong J. （通讯作者） Association between STAT3 gene Polymorphisms and Crohn's disease susceptibility: a case-control study in a Chinese Han population Diagn Pathol. 2014 29;9:104
Fan R, Zhong J （通讯作者）, Wang ZT, Li SY, Zhou J, Tang YH.. Evaluation of "top-down" treatment of early Crohn's disease by double balloon enteroscopy World J Gastroenterol. 2014 21;20(39):14479-87.
Yu LF, Zhong J （通讯作者）, Cheng SD, Tang YH, Miao F.L ow-dose azathioprine effectively improves mucosal healing in Chinese patients with small bowel Crohn's disease. J Dig Dis. 2014 15(4):180-7.
Wang L, Wang ZT, Zhang HX, Liu J, Lu SY, Fan R, Zhou J, Xia L, Sun YW, Zhong J （通讯作者）, Yuan YZ. Association between STAT3 gene polymorphisms and ulcerative colitis susceptibility: a case-control study in the Chinese Han population. Genet Mol Res. 2014 3;13(2):2343-8
Wang L,WangZT, Hu JJ, Fan R, Zhou J,Zhong J. （通讯作者） Polymorphisms of the vitamin D receptor gene and the risk of inflammatory bowel disease: a meta-analysis. Genet Mol Res. 2014 8;13(2):2598-610.
Wang ZT, Hu JJ, Fan R, Zhou J, Zhong J. （通讯作者） RAGE gene three polymorphisms with Crohn's disease susceptibility in Chinese Han population. World J Gastroenterol 2014 7;20(9):2397-402
Fan R, Zhong J （通讯作者）, Zheng S, Wang Z, Xu Y, Li S, Zhou J, Yuan F. MicroRNA-218 inhibits gastrointestinal stromal tumor cell and invasion by targeting KIT. Tumour Biol. 2014 35(5):4209-17
Hu JJ, Wang ZT,ZhongJ. （通讯作者） Lack of association between the interleukin 6 gene -174G>C polymorphism and colorectal cancer: evidence from a meta-analysis. Genet Mol Res. 2013 8;12(3):2205-14.
Wang Z, Hu J, Fan R, Zhou J, Zhong J. （通讯作者） Association between CD14 gene C-260T polymorphism and inflammatory bowel disease: a meta-analysis. PLoS One. 2012 2012;7(9):e45144.
Wang Z, Hu J, Zhong J. （通讯作者） Association between CD14 gene C-260T Meta-analysis of the NAD(P)H: quinine oxidoreductase 1 gene 609 C>T polymorphism with esophageal cancer risk. DNA Cell Biol. 2012 31(4):560-7.
Zhang Y, Wang ZT, Zhong J. （通讯作者） Lack of association between the 8-Meta-analysis demonstrates that the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene 609 C>T polymorphism is associated with increased gastric cancer risk in Asians. Genet Mol Res. 2012 13;11(3):2328-37.
Fan R, Zhong J （通讯作者）, Wang ZT, Yu LF,Tang YH, Hu WG, Zhu YB, Jin XL. Prognostic factors and outcome of resected patients with gastrointestinal stromal tumors of small intestine. Med Oncol. 2011 28 Suppl 1:S185-8.
Wang Z, Hu J, Cai W, Zhong J. （通讯作者） Lack of association between the 8-oxoguanine DNA glycosylase gene Ser326Cys polymorphism and gastric cancer: evidence from a meta-analysis. Asian Pac J Cancer Prev. 2011 12(12):3427-31