导师姓名： 李琛 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属瑞金医院 三级学科/
专业领域： 普外
导师类型： 硕士生导师 专业学位导师： 兼
联系方式： 上海交通大学医学院附属瑞金医院普外科leedoctor@sina.com
邮编： 200025 邮箱地址： leedoctor@sina.com

研究方向 (点击浏览详细信息)
胃癌外科治疗的临床和基础研究

社会任职
中国医师协会外科分会上消化道外科医师委员会常务委员、副秘书长
《中华胃肠外科杂志》通讯编委
中国抗癌协会上海胃肠肿瘤专业委员会委员
《外科理论与实践杂志》编辑部主任
中国抗癌协会胃癌专业委员会 委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
YG2017MS58 荧光磁性碳点纳米探针靶向抑制长链非编码RNA UCA1逆转胃癌细胞耐药的研究 上海交通大学医工交叉 2018-01~2020-12 21万元 课题负责人
*** 腹腔系统联合化疗治疗胃癌腹膜转移的临床多中心研究 上海交通大学医学院 2016-06~2019-06 200万元 课题参与人
13YZ025 miR-199a-3p通过ZHX1表达失调促进胃癌进展及其分子机制研究 上海市教委 2013-01~2015-12 8万元 课题负责人
胃癌病人尿液代谢物组生物标志物筛选和诊断模型的研究 上海市科委 2010-04~2013-03 10万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Yang ZY, Li C# （共同第一作者）, Yan C, Li JF, Yan M, Liu BY, Zhu ZG, Wu YL, Gu QL. . 2019; KIF14 promotes tumor progression and metastasis and is an independent predictor of poor prognosis in human gastric cancer BBA-Molecular Basis of Disease 2019 1865: 181-192
Pan J, Da Q, Xiang Z, Liu B, Li C （通讯作者） Three Biomarkers Predict Gastric Cancer Patients’ Susceptibility To Fluorouracil-based Chemotherapy. J of Cancer 2019 10(13): 2953-2960. doi: 10.7150/jca.31120
Pan J, Dai Q, Zhang T and Li C Palmitate acid promotes gastric cancermetastasis via FABP5/SP1/UCA1 pathway. Cancer Cell International 2019 19: 69
Pan J, Xiang Z, Dai Q, Wang Z, Liu B, Li C （通讯作者） Prediction of platinum-resistance patients of gastric cancer using bioinformatics J Cellular Biochemistry. 2019 Mar 25. doi: 10.1002/jcb.28621
Pan J, Fan Z, Wang Z, Dai Q, Xiang Z, Yuan F, Yan M, Zhu Z, Liu B, Li C* （通讯作者） CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway. J Exp Clin Cancer Res. 2019 38(1): 52. doi: 10.1186/s13046-019-1049-7
Feng R, Lu S, Sah BK, Beeharry MK, Zhang H, Yan M, Liu B, Li C* （通讯作者）, Zhu Z Serum miR-126 level combined with multi-detector computed tomography in the preoperative prediction of lymph node metastasis of gastric cancer. Cancer Biomark 2018 22(4): 773-780
Shi HP, Huang ML, Wang ZQ, Zheng YN, Zhu ZL, Sah BK, Liu WT, Yan M, Zhu ZG, Li C* （通讯作者） Clinicopathological and Prognostic Features of Surgical Management in Duodenal Gastrointestinal Stromal Tumors Dig Surg 2018 35(6): 498-507
Wang ZQ, Cai Q, Hu L, He CY, Li JF, Quan ZW, Liu BY, Li C* （通讯作者）, Zhu ZG Long noncoding RNA UCA1 induced by SP1 promotes cell proliferation via recruiting EZH2 and activating AKT pathway in gastric cancer Cell Death Dis 2017 8(6): e2839
Wang ZQ, He CY, Hu L, Shi HP, Li JF, Gu QL, Su LP, Liu BY*, Li C* （通讯作者）, Zhu ZG Long noncoding RNA UCA1 promotes tumor metastasis by inducing GRK2 degradation in gastric cancer Cancer Lett 2017 408: 10-21
Huang M, Ma X, Shi H, Hu L, Fan Z, Pang L, Zhu F, Yang X, Xu W, Liu B, Zhu Z, Li C （通讯作者） FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer Oncotarget 2017 10;8(43):74479-74493
Ma X, Huang M, Wang Z, Liu B, Zhu Z, Li C （通讯作者） ZHX1 Inhibits Gastric Cancer Cell Growth through Inducing Cell-Cycle Arrest and Apoptosis. J Cancer. 2016 7(1): 60-68.
Wang Z, Ma X, Cai Q, Wang X, Yu B, Cai Q, liu B, Zhu Z, Li C （通讯作者） MiR-199a-3p promotes gastric cancer progression by targeting ZHX1 FEBS lett 2014 28;588(23):4504-12
Wang Z, Cai Q, Jiang Z, Liu B, Zhu Z, Li C. （通讯作者） Prognostic role of microRNA-21 in gastric cancer: a meta-analysis Med Sci Monit. 2014 18;20:1668-74
Li C, Li JF, Cai Q, Qiu QQ, Yan M, Liu BY, Zhu ZG miRNA-199a-3p in plasma as a potential diagnostic biomarker for gastric cancer Ann Surg Oncol. 2013 20 Suppl 3:S397-405
Li C, Li JF, Cai Q, Qiu QQ, Yan M, Liu BY, Zhu ZG MiRNA-199a-3p: A potential circulating diagnostic biomarker for early gastric cancer J Surg Oncol. 2013 108(2):89-92
Ping Wan, Chen Li （通讯作者）, Min Yan, ChaoYan and Zheng Gang Zhu. Laparoscopy-Assisted versus Open Surgeryfor Gastrointestinal Stromal Tumors of Jejunum and Ileum: Perioperative Outcomes and Long-Term Follow-Up Experience. Am Surg 2012 78: 1399-1404
Ping Wan, Chao Yan, Chen Li （通讯作者）, Min Yan and Zheng Gang Zhu. Choices of Surgical Approaches for Gastrointestinal Stromal Tumors of the Stomach: Laparoscopic versus Open Resection. Dig Surg 2012 29(3): 243-250
Li Chen, Yan Min and Zhu Zheng Gang Nonpalliative surgical resection for gastric cancer patients with distant metastasis. J Invest Surg. J Invest Surg 2012 25(2): 100-106
Li C, Mei JW, Yan M, Chen MM, Yao XX, Yang QM, Zhou R, Zhu ZG Nasogastric decompression for radical gastrectomy for gastric cancer: a prospective randomized controlled study. Dig Surg 2011 28(3):167-72