导师姓名： 余迪 专业代码： 100100
性别： 男 专业名称： 基础医学
培养单位： 附属仁济医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师：
联系方式： di.yu@anu.edu.au
邮编： 邮箱地址： di.yu@anu.edu.au

研究方向 (点击浏览详细信息)
Tfh细胞的亚群及生物学功能
肿瘤免疫治疗
IL-2临床治疗自身免疫疾病
肠道微生物与自身免疫疾病

社会任职
Biotechnology and Biological Sciences Research Council (BBSRC, UK), Natural Science Foundation of China (NSFC, China), The Foundation of AIDS Research (amfAR, US)等基金的评审专家
Nature Immunology, Nature Medicine, Immunity, Cancer Cell等杂志特邀审稿人
国际细胞因子及干扰素协会(International Cytokine & Interferon Society, ICIS) 会员及联络工作组执委
国际免疫协会联盟(International Union of Immunological Societies, IUIS) 出版工作组执委

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
2017YFC** 基于系统生物学的重大自身免疫病防诊治精准化策略研究 科技部2017国家重点研发计划 2017-07~2019-12 195万元 子课题负责人
2014CB541903 系统性红斑狼疮的发病机理解析和诊治新策略硏究 科技部973子课题 2014-01~2018-12 61万元 课题参与人

学术论文 作者论文标题期刊名出版年卷期页码
Deng J, Fan C, Gao X, Zeng Q, Guo R, Wei Y, Chen Z, Chen Y, Gong D, Feng J, Xia Y, Xiang S, Gong S, Yuan L, Shen W, Shen W, Lin L, Jiang T, He D, Lu L, Chen X, Yu D. （通讯作者） Signal Transducer and Activator of Transcription 3 Hyperactivation Associates With Follicular Helper T Cell Differentiation and Disease Activity in Rheumatoid Arthritis. Front Immunol. 2018 2018.01226.
Leong YA, Atnerkar A, Yu D. （通讯作者） Human Immunodeficiency Virus Playing Hide-and-Seek: Understanding the TFH Cell Reservoir and Proposing Strategies to Overcome the Follicle Sanctuary. Front Immunol. 2017 2017.00622.
Leong YA, Chen Y, Ong HS, Wu D, Man K, Deleage C, Minnich M, Meckiff BJ, Wei Y, Hou Z, Zotos D, Fenix KA, Atnerkar A, Preston S, Chipman JG, Beilman GJ, Allison CC, Sun L, Wang P, Xu J, Toe JG, Lu HK, Tao Y, Palendira U, Dent AL, Landay AL, Pellegrini M, Comerford I, McColl SR, Schacker TW, Long HM, Estes JD, Busslinger M, Belz GT, Lewin SR, Kallies A*, Yu D*. （通讯作者） CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles Nature Immunology 2016 17(10):1187-96
He J#, Zhang X#, Wei Y#, Sun X, Chen Y, Jin Y, Hu X, Jia R, Xu C, Hou Z, Zhu L, Feng J, An Y, Li C, Liu X, Ye H, Ren L, Chen S, Zhang X, Su Y, Shen N, Guo J, Morand E, Yu D* （通讯作者）, Li Z*. Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus Nature Medicine 2016 22(9):991-3
Vinuesa CG*, Linterman MA*, Yu D* （通讯作者）, MacLennan IC. Follicular helper T cells Annual Review of Immunology 2016 34, 225-368
He J#, Tsai LM#, Leong YA, Hu X, Ma CS, Chevalier N, Sun X, Vandenberg K, Rockman S, Ding Y, Zhu L, Wei W, Wang C, Karnowski A, Belz GT, Ghali JR, Cook MC, Riminton DS, Veillette A, Schwartzberg PL, Mackay F, Brink R, Tangye SG, Vinuesa CG （通讯作者）, Mackay CR, Li Z*, Yu D*. Circulating precursor CCR7loPD-1hi CXCR5+ CD4+ T cells indicate follicular helper T cell activity and promote antibody responses upon antigen re-exposure Immunity 2013 39(4),770-781
Yu D, Rao S, Tsai LM, Lee SK, He Y, Sutcliffe EL, Srivastava M, Linterman M, Zheng L, Simpson N, Ellyard JI, Parish IA, Ma C, Li QJ, Parish CR, Mackay CR, Vinuesa CG Transcriptional repressor Bcl-6 directs Tfh lineage commitment Immunity 2009 31(3), 457-68
Yu D, Tan AH, Hu X, Athanasopoulos V, Simpson N, Silva DG, Giles KM, Leedman PJ, Huttloff A, Lam KP, Goodnow C, Vinuesa CG. Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA Nature 2007 450, 299-303.