导师姓名： 方炜 专业代码： 100201
性别： 女 专业名称： 内科学
培养单位： 附属仁济医院 三级学科/
专业领域： 肾病
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市浦东新区浦建路160号
邮编： 200127 邮箱地址： Fangwei_sh@126.com

研究方向 (点击浏览详细信息)
慢性肾脏病防治、腹膜透析的基础和临床研究

社会任职
《Am J Kid Dis》中文版执行编委
中国非公立医疗机构协会肾脏病透析专业委员会腹膜透析学组副组长
上海市医学会肾脏病分会委员
国际PDOPPS专家组成员
《中华肾脏病杂志》编委
中关村肾病血液净化创新联盟腹膜透析专委会副主任委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** IL-6 trans-signaling调控腹膜血管新生和通透性增高的机制研究 国家自然科学基金面上项目 2017-01~2020-12 58万元 课题负责人
** 生物电阻抗技术在腹透患者容量控制中的应用研究 上海市教委高峰高原计划“研究型医师”项目 2015-01~2017-12 100万元 课题负责人
** 血管周细胞和内皮细胞Cross-talk 调控腹膜通透性增高的机制研究 国家自然科学基金面上项目 2014-01~2017-12 69万元 课题负责人
114119a5900 内皮祖细胞在慢性肾脏疾病血管钙化加速中的作用研究 上海市科委医学引导类项目 2011-01~2013-06 10万元 课题负责人
Is there an association between dialysate Angiopoietin/Tie2 level and longitudinal changes of peritoneal transport in CAPD patients? 5th Asia PD College Research Grant 2009-07~2012-06 8.69万元 课题负责人
07QA14040 血管周细胞参与调控腹膜通透性的分子机制研究 上海市科委,启明星 2007-10~2009-09 13万元 课题负责人
** 血管周细胞/内皮细胞间Angiopoietin/Tie2通路调控腹膜通透性的实验研究 国家自然科学基金青年项目 2007-01~2009-12 22万元 课题负责人
04HX21009 腹膜血管新生机制的实验研究 横向课题 2005-01~2007-12 5万元 课题负责人
保持长期成功腹膜透析的临床和基础研究 上海市科委,重点科技攻关 2005-01~2007-12 15万元 课题负责人
04HX21009 腹膜血管新生机制的实验研究 横向课题 2005-01~2007-12 5万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Yan H, Ma D, Yang S, Ni Z, Fang W. （通讯作者） Effluent lipopolysaccharide is a prompt marker of peritoneal dialysis-related gram-negative peritonitis. Perit Dial Int 2020 2020 Jan 17
Ma D, Yan H, Yang X, Yu Z, Ni Z, Fang W. （通讯作者） Abdominal Aortic Calcification Score as a Predictor of Clinical Outcome in Peritoneal Dialysis Patients: A Prospective Cohort Study. BMC Nephrol 2020 21(1):151-160
Yang X, Yan H, Jiang N, Yu Z, Yuan J, Ni Z, Fang W. （通讯作者） IL-6 Trans-signaling Drives a STAT3-dependent Pathway That Leads to Structural Alterations of Peritoneal Membrane. Am J Physiol Renal Physiol 2019 318:F338-F353
Shi Y, Xiong Y, Lei Y, Li Z, Yan H, Yuan J, Ding F, Fang W. （通讯作者） Protective effect of COMP-angiopoietin-1 on peritoneal vascular permeability and peritoneal transport function in uremic peritoneal dialysis rats. Am J Transl Res 2019 11(9):5932-5943
Yang X, Tong Y, Yan H, Ni Z, Qian J, Fang W. （通讯作者） High Intraperitoneal Interleukin-6 Levels Predict Peritonitis in Peritoneal Dialysis Patients: A Prospective Cohort Study. Am J Nephrol 2018 47(5):317-324
Yang X, Zhang H, Shi Y, Yu Z, Yan H, Ni Z, Qian J, Fang W. （通讯作者） Association of Serum Angiopoietin-2 with Malnutrition, Inflammation, Atherosclerosis and Valvular Calcification Syndrome and Outcome in Peritoneal Dialysis Patients: a Prospective Cohort Study. J Transl Med 2018 16(1):312-322
Shi Y, Yan H, Yuan J, Zhang H, Huang J, Ni Z, Qian J, Fang W. （通讯作者） Different patterns of inflammatory and angiogenic factors are associated with peritoneal small solute transport and peritoneal protein clearance in peritoneal dialysis patients. BMC Nephrology 2018 19(1):119-127
Gong L, Zheng D, Yuan J, Cao L, NI Z, Fang W. （通讯作者） Elevated levels of serum sclerostin are linked to adverse cardiovascular outcomes in peritoneal dialysis patients. Int Urol Nephrol 2018 50(5):955-961
Li Z, Yan H, Yuan J, Cao L, Lin A, Dai H, Ni Z, Qian J, Fang W. （通讯作者） Pharmacological inhibition of heparin-binding EGF-like growth factor promotes peritoneal angiogenesis in a peritoneal dialysis rat model. Clin Exp Nephrol 2017 22(2):257-265
Shi Y, Zheng D, Zhang L, Yu Z, Yan H, Ni Z, Qian J, Fang W. （通讯作者） Six-minute walk test predicts all-cause mortality and technique failure in ambulatory peritoneal dialysis patients Nephrology (Carlton) 2017 22(2):118-124
Gong L, Liu Y, Qian J, Ni Z, Fang W. （通讯作者） Hydroxyapatite nanocrystals stimulate osteogenic differentiation in primary human aortic smooth muscle cells by activation of oxidative?stress and the ERK pathway. Int J Clin Exp Pathol 2017 10(7):7726-7733
Yan H, Fang W （通讯作者）, Lin A, Cao L, Ni Z, Qian J. Three Versus 4 Daily Exchanges and Residual Kidney Function Decline in Incident CAPD Patients: A Randomized Controlled Trial. Am J Kidney Dis 2017 69(4):506-513
Gong L, Liu Y, Qian J, Ni Z, Fang W. （通讯作者） Hydroxyapatite nanocrystals stimulate osteogenic differentiation in primary human aortic smooth muscle cells by activation of oxidative stress and the ERK pathway. Int J Clin Exp Pathol 2017 10(7) :7726-7733
Yang X, Lin A, Jiang N, Yan H, NI Z, Qian J, Fang W. （通讯作者） Interleukin-6 trans-signaling induces VEGF synthesis partly via Janus kinases-STAT3 pathway in human mesothelial cells Nephrology (Carlton) 2017 22(2):150-158
Liu Y, Zhang L, Ni Z, Qian J, Fang W. （通讯作者） Calcium Phosphate Crystals from Uremic Serum Promote Osteogenic Differentiation in Human Aortic Smooth Muscle Cells Calcif Tissue Int 2016 99(5):543-555
Yan H, Bian Z, Zhang W, Fang Y, Ni Z, Qian J, Fang W. （通讯作者） Surgical intervention after catheter removal in a case of refractory peritoneal dialysis-related peritonitis Case Rep Nephrol Dial 2015 5(1):66-70
Yu Z, Gu L, Pang H, Fang Y, Yan H, Ni Z, Qian J, Fang W. （通讯作者） Sodium thiosulfate: an emerging treatment for calciphylaxis in dialysis patients Case Rep Nephrol Dial 2015 5(1):77-82
Lei Y, Xiong Y, Zhang L, Yan H, Li Z, Cao L, Huang J, Gu A, Ni Z, Qian J, Fang W. （通讯作者） Comparison of Long-term Outcomes between Peritoneal Dialysis Patients with Diabetes as a Primary Renal Disease or as a Comorbid Condition PloS One 2015 10(5):e**
Jiang N, Fang W, Yang X, Zhang L, Yuan J, Lin A, Ni Z, Qian J. Dietary phosphorus intake and distribution in Chinese peritoneal dialysis patients with and without hyperphosphatemia Clin Exp Nephrol 2015 19(4):694-700
Tan K, Yu Z, Fang W, Lin A, Ni Z, Qian J, Woodrow G, Jenkins S, Wilkie M, Davies SJ. Longitudinal bioimpedance vector plots add little value to fluid management of peritoneal dialysis patients Kidney Int 2015 89(2):487-497
Yang X, Zhang H, Hang Y, Yan H, Lin A, Huang J, Ni Z, Qian J, Fang W. （通讯作者） Intraperitoneal Interleukin-6 Levels Predict Peritoneal Solute Transport Rate: A Prospective Cohort Study Am J Nephrol 2014 39(6):459-65
Fang W （通讯作者）, Ni Zi, Qian J. Key factors for a high-quality peritoneal dialysis program--the role of the PD team and continuous quality improvement Perit Dial Int 2014 34:S35-42
Liu Y, Zhang L, Lin A, Ni Z, Qian J, Fang W. （通讯作者） Impact of break-in period on the short-term outcomes of patients start on peritoneal dialysis Perit Dial Int 2014 34(1):49-56
Yuan J, Fang W （通讯作者）, Lin A, Ni Z, Qian J. Angiopoietin-2/Tie2 signaling involved in TNF-α induced peritoneal angiogenesis Int J Artif Organs 2012 35(9):655-62
Yuan J, Fang W （通讯作者）, Zhang W, Ni Z, Qian J. Treatment of nephrotic idiopathic membranous nephropathy with monthly i.v. pulse cyclophosphamide and oral steroids: a single centre's retrospective study Nephrology 2011 16(4):440-5
Fang W, Yang X, Bargman JM, Oreopoulos DG. Association between pulse pressure and mortality in patients undergoing peritoneal dialysis Perit Dial Int 2009 29(2):163-70
Yuan J, Fang W （通讯作者）, Ni Z, Dai H, Lin A, Cao L, Qian J. Peritoneal morphologic changes in a peritoneal dialysis rat model correlate with angiopoietin/Tie-2 Pediatr Nephrol 2009 24(1):163-70
Fang W, Oreopoulos DG, Bargman JM. Use of ACE inhibitors or angiotensin receptor blockers and survival in patients on peritoneal dialysis Nephrol Dial Transplant 2008 23(11):3704-10
Fang W, Qian J, Lin A, Rowaie F, Ni Z, Yao Q, Bargman JM, Oreopoulos DG. Comparison of peritoneal dialysis practice patterns and outcomes between a Canadian and a Chinese centre Nephrol Dial Transplant 2008 23(12):4021-8
Fang W, Yang X, Kothari J, Khandelwal M, Naimark D, Jassal SV, Bargman JM, Oreopoulos DG. Patient and technique survival of diabetics on peritoneal dialysis: one-center's experience and review of the literature Clin Nephrol 2008 69(3):193-200
Fang W, Mullan R, Shah H, Mujais S,Bargman JM, Oreopoulos DG. Comparison between bicarbonate/lactate and standard lactate dialysis solution in peritoneal transport and ultrafiltration: a prospective, crossover single-dwell study Perit Dial Int 2008 28(1):35-43