导师姓名： 刘倩 专业代码： 100208
性别： 女 专业名称： 临床检验诊断学
培养单位： 附属仁济医院 三级学科/
专业领域：
导师类型： 硕士生导师 专业学位导师：
联系方式：
邮编： 邮箱地址： qq**@163.com

研究方向 (点击浏览详细信息)
金黄色葡萄球菌致病机制的研究
凝固酶阴性葡萄球菌抑制致病菌的作用机制

社会任职
上海市微生物学会青年工作委员会委员
上海市微生物学会会员
上海市医学会检验医学专科分会学组成员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
20ZR** 共生表皮葡萄球菌依赖脂蛋白/TLR2信号通路促进宿主免疫防御 上海市科委 2020-07~2023-06 20万元 课题负责人
20QA** 共生表皮葡萄球菌通过SaeRS二元调控系统抑制高致病金黄色葡萄球菌毒力的分子机制 上海市科委启明星项目 2020-06~2023-05 40万元 课题负责人
** 金黄色葡萄球菌ATP依赖蛋白酶ClpP与毒力调控蛋白SaeS之间的调节关系 国家自然科学基金 2018-01~2021-12 53万元 课题负责人
** 金黄色葡萄球菌金属蛋白酶Eep促进细菌毒力的分子机制 国家自然科学基金 2016-01~2018-12 21.6万元 课题负责人
14ZR** 金黄色葡萄球菌ATP依赖蛋白酶系统对毒力调节因子SaeRS稳定性的调控 上海市科委 2014-07~2017-06 10万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Liu Q, Liu Q, Meng H, Lv H, Liu Y, Liu J, Wang H, He L, Qin J, Wang Y, Dai Y, Otto M, Li M Staphylococcus epidermidis contributes to healthy maturation of the nasal microbiome by stimulating antimicrobial peptide production Cell Host Microbe 2020 27(1):68-78
Cheng D, Lv H, Yao Y, Cheng S, Huang Q, Wang H, Liu X, Bae T, Li M, Liu Q. （通讯作者） Roles of the Site 2 Protease Eep in Staphylococcus aureus J Bacteriol 2020 202(15)
Yeo WS, Anokwute C, Marcadis P, Levitan M, Ahmed M, Bae Y, Kim K, Kostrominova T, Liu Q （通讯作者）, Bae T A membrane-bound transcription factor is proteolytically regulated by the AAA+ protease FtsH in Staphylococcus aureus J Bacteriol 2020 JB.00019-20
Dai Y, Liu J, Guo W, Meng H, Huang Q, He L, Gao Q, Lv H, Liu Y, Wang Y, Wang H, Liu Q （通讯作者）, Li M. Decreasing methicillin-resistant Staphylococcus aureus (MRSA) infections is attributable to the disappearance of predominant MRSA ST239 clones, Shanghai, 2008-2017. Emerg Microbes Infect 2019 8(1):471-478.
He L, Meng H, Liu Q （共同第一作者）, Hu M, Wang Y, Chen X, et al. Distinct virulent network between healthcare- and community-associated Staphylococcus aureus based on proteomic analysis Clin Proteomics. 2018 15:2.
Wang Y, Liu Q, Liu Q （共同第一作者）, Gao Q, Lu H, Meng H, et al. Phylogenetic analysis and virulence determinant of the host-adapted Staphylococcus aureus lineage ST188 in China Emerg Microbes Infect. 2018 7(1):45.
Liu Q （通讯作者）,Wang X,Qin J,Cheng S, Yeo WS, He L, Ma X, Liu X, Li M, Bae T. The ATP-dependent protease ClpP inhibits biofilm formation by regulating Agr and cell wall hydrolase Sle1 in Staphylococcus aureus. Front Cell Infect Microbiol 2017 7:181
Liu Q, Hu M, Yeo WS, He L, Li T, Zhu Y, Meng H, Wang Y, Lee H, Liu X, Li M, Bae T. Rewiring of the FtsH regulatory network by a single nucleotide change in saeS of Staphylococcus aureus. Sci Rep 2017 16;7(1):8456.
Dai Y, Wang Y, Liu Q （共同第一作者）, Gao Q, Lu H, Meng H, Qin J, Hu M, Li M. A Novel ESAT-6 Secretion System-Secreted Protein EsxX of Community-Associated Staphylococcus aureus Lineage ST398 Contributes to Immune Evasion and Virulence Front Microbiol 2017 8:819
Liu Y, Liu Q （共同第一作者）, Qi L, Ding T, Wang Z, Fu J, Hu M, Li M, Song J, Liu X. Temporal regulation of a Salmonella Typhimurium virulence factor by the transcriptional regulator YdcR. Mol Cell Proteomics 2017 pii: mcp.M117.068296
Liu Q, Yeo WS, Bae T The SaeRS Two-Component System of Staphylococcus aureus. Genes (Basel). 2016 7(10)
Liu Q, Du X, Hong X, Li T, Zheng B, He L, Wang Y, Otto M, and Li M Targeting the surface protein SasX by active and passive vaccination to reduce Staphylococcus aureus colonization and infection Infect and Immun 2015 83(5):2168-2174
Cho H, Jeong DW, Liu Q, Yeo WS, Vogl T, Skaar EP, Chazin WJ, Bae T Calprotectin increases the activity of the SaeRS two component system and murine mortality during Staphylococcus aureus infections Plos Pathog 2015 11(7):e**
Liu Q, Cho H, Yeo W, and Bae T. The Extracytoplasmic Linker Peptide of the Sensor Protein SaeS Tunes the Kinase Activity Required for Staphylococcal Virulence in Response to Host Signals Plos Pathog 2015 11(4):e**,
Lijek RS, Luque SL, Liu Q, Parker D, Bae T, Weiser JN Protection from the acquisition of Staphylococcus aureus nasal carriage by cross-reactive antibody to a pneumococcal dehydrogenase Proc Natl Acad Sci USA 2012 109(34), 13823-13828
Liu Q, Fan J, Niu C, Wang D, Wang J, Wang X, Villaruz AE, Li M, Otto M, Gao Q The eukaryotic-type serine/threonine protein kinase Stk is required for biofilm formation and virulence in Staphylococcus epidermidis Plos ONE 2011 6(9), e25380,