导师姓名： 苏青 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属新华医院 三级学科/
专业领域： 内分泌与代谢病
导师类型： 博士生导师 专业学位导师： 兼
联系方式：
邮编： 邮箱地址： suqing139@126.com

研究方向 (点击浏览详细信息)
甲状腺疾病发病机制及诊治
糖尿病及慢性并发症的发病机制研究

社会任职
中国医师协会内分泌代谢分会委员
中华医学会糖尿病分会委员
上海市医学会糖尿病专科分会副主任委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** AGEs-RAGE轴抑制β细胞胞葬在胰岛巨噬细胞极化失衡中的作用及机制研究 国家自然科学基金面上项目 2020-01~2023-12 55万元 课题负责人
** ChREBP在高糖诱导的胰岛β细胞去分化过程中的作用 国家自然科学基金 2017-01~2020-12 58万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Zhang HM, Qin L, Sheng CS, Niu Y, Gu H, Lu S, Yang Z, Tian J, Su Q （通讯作者） ASCVD risk stratification modifies the effect of HbA1c on cardiovascular events among patients with type 2 diabetes mellitus with basic to moderate risk BMJ Open Diabetes Res Care 2020 8(1):e000810
Ying Chen, Huandong Lin, Li Qin,Youli Lu, Lin Zhao, Mingfeng Xia,Jingjing Jiang, Xiaomu Li, Chen Yu,Geng Zong, Yan Zheng, Xin Gao,Qing Su （通讯作者）, and Xiaoying Li Fasting Serum Fructose Levels Are Associated With Risk of Incident Type 2 Diabetes in Middle-Aged and Older Chinese Population Diabetes Care 2020 Publish Ahead of Print
Dong X, Yu S, Wang Y, Yang M, Xiong J, Hei N, Dong B, Su Q （通讯作者）, Chen J. (Pro)renin receptor-mediated myocardial injury, apoptosis, and inflammatory response in rats with diabetic cardiomyopathy. J Biol Chem 2019 294(20):8218-8226
Li B, Wu X, Chen H, Zhuang C, Zhang Z, Yao S, Cai D, Ning G, Su Q （通讯作者） miR199a-5p inhibits hepatic insulin sensitivity via suppression of ATG14-mediated autophagy Cell Death Dis 2018 14;9(3):405
Zhang H, Niu Y, Gu H, Lu S, Zhang W, Li X, Yang Z, Qin L, Su Q. （通讯作者） Low serum adiponectin is a predictor of progressing to non-alcoholic fatty liver disease Journal of Clinical Laboratory Analysis 2018 2018 Nov 2:e22709
Ran H, Zhu Y, Deng R, Zhang Q, Liu X, Feng M, Zhong J, Lin S, Tong X, Su Q （通讯作者） Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN J Exp Clin Cancer Res 2018 37(1):54
Su Q, Liu J, Li P, Qian L, Yang W Relative Contribution of Fasting and Postprandial Blood Glucose in Overall Glycemic Control: Post Hoc Analysis of a Phase IV Randomized Trial Diabetes Ther 2018 9(3):987-999
Kong X, Lu AL, Yao XM, Hua Q, Li XY, Qin L, Zhang HM, Meng GX, Su Q （通讯作者） Activation of NLRP3 Inflammasome by Advanced Glycation End Products Promotes Pancreatic Islet Damage Oxid Med Cell Longev. 2017 2017;2017:**
Lin N, Li XY, Zhang HM, Yang Z, Su Q （通讯作者） microRNA-199a-5p mediates high glucose-induced reactive oxygen species production and apoptosis in INS-1 pancreatic β-cells by targeting SIRT1 Eur Rev Med Pharmacol Sci. 2017 21(5):1091-1098
Zhang W, Yang Z, Niu Y, Li X, Zhu L, Lu S, Zhang H, Fan J, Ning G, Qin L, Su Q. （通讯作者） Association of calf circumference with insulin resistance and non-alcohol fatty liver disease: the REACTION study BMC Endocr Disord 2017 17(1):28
Zhang H, Dong Y, Su Q （通讯作者） Perinatal hypothyroidism modulates antioxidant defence status in the developing rat liver and heart Can J Physiol Pharmacol 2017 95(2):185-189
Zhang HM, Zhou YQ, Dong Y, Su Q （通讯作者） Identification and functional characterization of a novel thyrotropin receptor mutation (V87L) in a Chinese woman with subclinical hypothyroidism Exp Ther Med 2017 13(1):290-294
Su Q, Liu C, Zheng H, Zhu J, Li PF, Qian L, Yang WY Comparison of insulin lispro mix 25 with insulin lispro mix 50 as insulin starter in Chinese patients with type 2 diabetes mellitus (CLASSIFY study): Subgroup analysis of a Phase 4 open-label randomized trial J Diabetes 2017 9(6):575-585
Zhang H, Yang Z, Zhang W, Niu Y, Li X, Qin L, Su Q （通讯作者） White blood cell subtypes and risk of type 2 diabetes J Diabetes Complications 2017 31(1):31-37
Qin L, Zhang W, Yang Z, Niu Y, Li X, Lu S, Xing Y, Lin N, Zhang H, Ning G, Fan J, Su Q （通讯作者） Impaired lung function is associated with non-alcoholic fatty liver disease independently of metabolic syndrome features in middle-aged and elderly Chinese BMC Endocr Disord 2017 17(1):18
Zhang H, Yan C, Yang Z, Zhang W, Niu Y, Li X, Qin L, Su Q （通讯作者） Alterations of serum trace elements in patients with type 2 diabetes J Trace Elem Med Biol. 2017 40:91-96
Deng R, Wu H, Ran H, Kong X, Hu L, Wang X, Su Q （通讯作者） Glucose-derived AGEs promote migration and invasion of colorectal cancer by up-regulating Sp1 expression Biochim Biophys Acta 2017 1861(5 Pt A):1065-1074
Yang Z, Zhang W, Zhu L, Lin N, Niu Y, Li X, Lu S, Zhang H, Wang X, Wen J, Ning G, Qin L, Su Q （通讯作者） Resting heart rate and impaired glucose regulation in middle-aged and elderly Chinese people: a cross-sectional analysis BMC Cardiovasc Disord 2017 17(1):246
Qin L, Yang Z, Zhang W, Gu H, Li X, Zhu L, Lu S, Xing Y, Zhang H, Niu Y, Ning G, Su Q （通讯作者） Metabolic syndrome and osteoporotic fracture: a population-based study in China BMC Endocr Disord 2016 16(1):27
Niu Y, Zhang W, Yang Z, Li X, Fang W, Zhang H, Wang S, Zhou H, Fan J, Qin L, Su Q （通讯作者） Plasma osteoprotegerin levels are inversely associated with nonalcoholic fatty liver disease in patients with type 2 diabetes: A case-control study in China Metabolism 2016 65(4):475-81
Qin L, Yang Z, Zhang W, Gu H, Lu S, Shi Q, Xing Y, Li X, Li R, Ning G, Su Q （通讯作者） Association between metabolic syndrome and lung function in middle-aged and elderly Chinese individuals Diabetes Res Clin Pract 2015 Jun;108(3):e46-8
Zhang H, Yang Z, Zhang W, Niu Y, Li X, Qin L, Su Q （通讯作者） HIGHER SERUM OSTEOPROTEGERIN LEVELS IN SUBJECTS WITH THYROID NODULES Endocr Pract 2015 Nov 23. [Epub ahead of print
Zhuhua Z, Zhiquan W, Zhen Y, Yixin N, Weiwei Z, Xiaoyong L, Yueming L, Hongmei Z, Li Q, Qing S （通讯作者） A novel mice model of metabolic syndrome: the high-fat-high-fructose diet-fed ICR mice Exp Anim 2015 Oct 23;64(4):435-42
Niu Y, Zhang W, Yang Z, Li X, Wen J, Wang S, Zhang H, Wang X, Zhou H, Fang W,Qin L, Su Q （通讯作者） Association of plasma osteoprotegerin levels with the severity of lower extremity arterial disease in patients with type 2 diabetes BMC Cardiovasc Disord 2015 Aug 11;15:86
Niu Y, Yang Z, Li X, Zhang W, Lu S, Zhang H, Chen X, Zhu L, Xing Y, Ning G, Qin L,Su Q （通讯作者） Association of osteoprotegerin with impaired glucose regulation and microalbuminuria: the REACTION study BMC Endocr Disord. 2015 Dec 1;15(1):75
Zhang W, Yang Z, Li X, Wen J, Zhang H, Wang S, Wang X, Zhou H, Fang W, Qin L,Su Q （通讯作者） The functional Q84R polymorphism of TRIB3 gene is associated with diabetic nephropathy in Chinese type 2 diabetic patients Gene 2015 Jan 25;555(2):357-61.
Kong X, Ma MZ, Huang K, Qin L, Zhang HM, Yang Z, Li XY, Su Q. （通讯作者） Increased plasma levels of the methylglyoxal in patients with newly diagnosed type 2 diabetes. J Diabetes 2014 Epub ahead of print
Qin L, Yang Z, Gu H, Lu S, Shi Q, Xing Y, Li X, Li R, Ning G, Su Q （通讯作者） Association between serum uric acid levels and cardiovascular disease in middle-aged and elderly Chinese individuals BMC Cardiovasc Disord 2014 14(26):1471-2261
Jian W, Peng W, Xiao S, Li H, Jin J, Qin L, Dong Y, Su Q （通讯作者） Role of serum vaspin in progression of type 2 diabetes: a 2-year cohort study PLoS One 2014 9(4):94-763
Kong X, Ma MZ, Qin L, Zhang Y, Li XY, Wang GD, Su Q （通讯作者）, Zhang DY Pioglitazone enhances the blood pressure-lowering effect of losartan via synergistic attenuation of angiotensin II-induced vasoconstriction J Renin Angiotensin Aldosterone Syst 2014 Sep;15(3):259-70
Chen H, Wu L, Li Y, Meng J, Lin N, Yang D, Zhu Y, Li X, Li M, Xu Y, Wu Y, Tong X,Su Q （通讯作者） Advanced glycation end products increase carbohydrate responsive element binding protein expression and promote cancer cell proliferation. Mol Cell Endocrinol. 2014 Sep;395(1-2):69-78.
Zhang HM, Lin N, Dong Y （通讯作者）, Su Q, Luo M. Protein kinase cα is involved in impaired perinatal hypothyroid rat brain development. Journal of neuroscience research 2013 92(2): 211-219
Jian WX, Peng WH, Jin J, Chen XR, Fang WJ, Wang WX, Qin L, Dong Y, Su Q. （通讯作者） Association between serum fibroblast growth factor 21 and diabetic nephropathy. Metabolism 2012 61(6): 853-859
Lin N, Zhang HM, Su Q. （通讯作者） Advanced glycation end products induce pancreatic beta cell injury through oxidative stress. Diabetes Metab 2012 38(3): 250-257
Du SC, Ge QM, Lin N, Dong Y, Su Q. （通讯作者） ROS-mediated lipopolysaccharide-induced apoptosis in INS-1 cells by modulation of Bcl-2 and Bax. Cell Mol Biol (Noisy-le-grand) 2012 58(sul): 1654-1659
Lin N, Chen HB, Zhang HM, Wan XY, Su Q. （通讯作者） Mitochondrial ROS inhibition ameliorates endoplasmic reticulum stress in palmitate-induced INS-1 beta cell death Endocrine 2012 42(1): 107-117
Zhang HM, Lin N, Dong Y, Su Q （通讯作者）, Luo M. Effect of perinatal thyroid hormone deficiency on expression of rat hippocampal conventional protein kinase C isozymes. Mol Cell Biochem 2011 353(1-2): 65-71
Ge QM, Dong Y, Su Q. （通讯作者） Effects of glucose and advanced glycation end products on oxidative stress in MIN6 cells Cell Mol Biol (Noisy-le-grand) 2010 56 Suppl:OL1231-8
Ge QM, Dong Y, ZHANG HM,Su Q. （通讯作者） Effects of intermittent high glucose on oxidative stress in endothelial cells. Acta Diabetol 2009 Epub ahead of print
Zhang HM, Su Q （通讯作者）, Luo M Thyroid hormone regulates the expression of SNAP-25 during rat brain development Mol Cell Biochem 2008 307:169-175
Dong Y, Sheng H, Chen X, Yin J, Su Q （通讯作者） Deletion of the V2 vasopressin receptor gene in two Chinese patients with nephrogenic diabetes insipidus BMC Genet 2006 7:53-55