导师姓名： 蒋更如 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属新华医院 三级学科/
专业领域： 肾病
导师类型： 博士生导师 专业学位导师： 兼
联系方式：
邮编： jianggeng-ru@hotmail.com 邮箱地址： jianggeng-ru@hotmail.com

研究方向 (点击浏览详细信息)
ESRD患者心血管疾病防治研究
IgA肾病的临床和基础研究
膜性肾病临床研究

社会任职
世界华人肾脏医师协会常委
中华医学会肾脏病分会常委
中国医师协会肾脏内科医师分会常委
中国生物医学工程学会透析移植分会委员
中国医药卫生文化协会肾病与血液净化专业委员会副主任委员
华东地区肾脏病协作组常委
上海市医师协会肾脏内科医师分会副会长
中国医药教育协会泌尿与血液净化专业委员会常委
上海市罕见病诊治中心主任
上海市肾脏病学会主任委员
中国医院协会血液净化中心管理分会委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
16CR1021A 血液透析联合血液灌流治疗维持性血液透析患者生存率影响的多中心、开放、随机、平行对照研究 上海申康医院发展中心临床技能与临床创新三年行动计划 2016-12~2019-06 200万元 课题负责人
12DJ** 急性肾损伤关键发病机制与防诊治策略的应用基础研究 上海市科委 2013-11~2015-10 20万元 课题参与人
** 人工诱导突变的尿素转运蛋白B 在5/6 肾切除大鼠肠上皮细胞表达及功能研究 国家自然科学基金 2013-01~2016-12 70万元 课题负责人
自发性IgAN动物模型的建立 上海市科委 2012-10~2014-09 15万元 课题负责人
大规格聚醚砜透析器的开发 上海市科委 2011-10~2013-09 10万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Lin FJ, Yao L, Hu XQ, Bian F, Ji G, Jiang GR, Gale DP, Ren HQ. First identification of PODXL nonsense mutations in autosomal dominant focal segmental glomerulosclerosis. Clin Sci (Lond) 2019 133: 9-21.
Lin FJ, Zhang X, Huang LS, Zhou X, Ji G, Luo R, GengRu Jiang* （通讯作者）, Lu W. De novo cardiac valve calcification after hemodialysis in end-stage renal disease patients predicts future cardiovascular events: a longitudinal cohort study. Cardiorenal Med 2019 9: 229-39.
Liu M, Liu J, Hao S, Wu P, Zhang X, Xiao Y, Jiang G* （通讯作者）, Huang X. Higher activation of the interferon-gamma signaling pathway in systemic lupus erythematosus patients with a high type I IFN score: relation to disease activity. Clin Rheumatol 2018 37: 2675-84.
Lin F, Zhang D, Chang J, Tang X, Guan W, Jiang G, Zhu C, Bian F. THSD7A-associated membranous nephropathy in a patient with neurofibromatosis type 1. European Journal of Medical Genetics 2018 61(2):84-88.
Zhang D, Zou J, Zhang C, Zhang W, Lin F, Jiang G. （通讯作者） Clinical and Histological Features of Phospholipase A2 Receptor-Associated and Thrombospondin Type-I Domain-containing 7A-Associated Idiopathic Membranous Nephropathy: A Single Center Retrospective Study from China. medical science monitor 2018 24:5076-5083.
Chen SJ, Shan JP, Niu W, Lin FJ, Liu S, Wu P, Sun LJ, Lu W, Jiang GR （通讯作者） Micro RNA-155 inhibitor as a potential therapeutic strategy for the treatment of acute kidney injury (AKI): a nano medicine perspective RSC Advances 2018 8:15890
Xie Y, Yang B, Jiang G, Lu W, Ronco C. Spontaneous perirenal hemorrhage in hemodialysis patient treated with selective embolization: A case series and review of the literature Hemodialysis International 2018 22(2):222-227
Lu W, Jiang GR; HD/HP versus HD trial Group. （通讯作者） Randomised, open-label, multicentre trial comparing haemodialysis plus haemoperfusion versus haemodialysis alone in adult patients with end-stage renal disease (HD/HP vs HD): study protocol. BMJ Open 2018 8(7):e022169
Lu W, Jiang G* （通讯作者） HD/HP versus HD trial Group. Randomised, open-label, multicentre trial comparing haemodialysis plus haemoperfusion versus haemodialysis alone in adult patients with end-stage renal disease (HD/HP vs HD): study protocol. BMJ Open 2018 8: e022169.
Chen SJ, Wu P, Sun LJ, Zhou B, Niu W, Liu S, Lin FJ, Jiang GR （通讯作者） miR-204 regulates epithelial-mesenchymal transition by targeting SP1 in the tubular epithelial cells after acute kidney injury induced by ischemia-reperfusion. Oncology reports 2017 37(2): 1148-1158
Sun LJ, Sun YN, Shan JP, Jiang GR. Effects of mineralocorticoid receptor antagonists on the progression of diabetic nephropathy. J Diabetes Investig 2017 8(4):609-618.
Sun L, Guo Z, Shan J, Jiang G （通讯作者） Fasting urinary calcium to creatinine ratio for the evaluation of calcium nephrolithiasis in adults. Brit J Biomed Sci 2017 4(2):101-103.
Sun LJ, Sun YN, Chen SJ, Liu S, Jiang GR. （通讯作者） Resveratrol attenuates skeletal muscle atrophy induced by chronic kidney disease via MuRF1 signaling pathway. Biochem Biophys Res Commun 2017 487(1):83-89
Li-Jing Sun, Bo Xu, Shun-Jie Chen, Shuang Liu, Bin He, Geng-Ru （通讯作者） Effects of spironolactone on cardiovascular outcomes in chronic kidney disease and end-stage renal disease patients international journal of clinical and experimental medicine 2016 9(2):794-803
Lin FJ, Lu W, Gale D, Yao Y, Zou R, Bian F, Jiang GR （通讯作者） Delayed diagnosis of Townes-Brocks syndrome with multicystic kidneys and renal failure caused by a novel SALL1 nonsense mutation: A case report. Experimental and Therapeutic Medicine 2016 11(4):1249-1252
Jun Zou, Yi Yu, Ping Wu, Fu-Jun Lin, Yao Yao, Yun Xie, Geng-Ru Jiang （通讯作者） Independent of Renal Function in Hospitalized Patients with Chronic Kidney Disease International Journal of Cardiology 2016 10.1016/j.ijcard.2016.06.181
Fujun Lin, Fan Bian, Jun Zou, Xiangru Wu, Jianping Shan, Wei Lu, Yao Yao, Gengru Jiang and Daniel Philip Gale （通讯作者） Whole exome sequencing reveals novel COL4A3 and COL4A4 mutations and resolves diagnosis in Chinese families with kidney disease BMC Nephrology 2014 15:175
Yan Dong, Lin Yang, Fang Fang, Jing Zhang, Gengru Jiang & Shijie Xu （通讯作者） Genome-wide scan for hypertension linkage to chromosome Indian J Med Res 2013 137: 935-941
FU-JUN LIN, GENG-RU JIANG （通讯作者）, JIAN-PING SHAN, CHUN ZHU,JUN ZOU& XIANG-RU WU Imbalance of regulatory T cells to Th17 cells in IgA nephropathy. Scandinavian Journal of Clinical & Laboratory Investigation Scandinavian Journal of Clinical & Laboratory Investigation 2012 72: 221–229
Gengru Jiang, Fatma Akar,Scott Cobbs Blood pressure regulates the activity and function of the Na-K-2Cl cotransporter in vascular smooth muscle. Am J Physiol Heart Circ Physiol 2004 286:H1552-H1557
Gengru Jiang, Scott Cobbs, Janet D.Klein Aldosterone regulates the Na-K-2Cl cotransporter in vascular smooth muscle Hypertension 2003 41:1131-1135
Gengru Jiang, Janet D. Klein, W. Charles O’Neill Growth factors stimulate the Na-K-2Cl cotransporter NKCC1 through a novel Cl--dependent mechanism Am J Physiol Cell Physiol 2001 281:C1948-C1953