导师姓名： 李栋 专业代码： 100214
性别： 男 专业名称： 肿瘤学
培养单位： 附属第九人民医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师：
联系方式： -6954
邮编： ** 邮箱地址： adongly@hotmail.com

研究方向 (点击浏览详细信息)
肿瘤放疗敏感性机制研究
髓系造血干细胞定向分化诱导机制研究

社会任职

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** NLRP12通过自噬调控巨噬细胞定向分化的功能和机制研究 国家自然基金 （面上项目) 2020-01~2023-12 55万元 课题负责人
** 基于胚胎干细胞来源的髓系细胞分化机制研究 国家自然基金 （面上项目) 2014-01~2017-12 70万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Lei Bian, Yiling Meng, Meichao Zhang, Zhuying Guo, Furao Liu, Weiwen Zhang, Xue Ke, Yuxuan Su, Meng Wang, Yuan Yao, Lizhong Wu, Dong Li# （通讯作者） ATM Expression Is Elevated in Established Radiation-Resistant Breast Cancer Cells and Improves DNA Repair Efficiency Int J Biol Sci 2020 16(7):1096-1106
Ci Xu, Meichao Zhang, Lei Bian, Yanyan Li, Yuan Yao, Dong Li# （通讯作者） N-glycosylated SGK196 suppresses the metastasis of basal-like breast cancer cells Oncogenesis 2020 9(1):4-15
Furao Liu,Zebin Xia,Meichao Zhang,Jiping Ding,Yang Feng, Jianwei Wu,Yun Dong,Wei Gao,Zengwei Han,Yuanhua Liu,Yuan Yao,Dong Li# （通讯作者） SMARCAD1 Promotes Pancreatic Cancer Cell Growth and Metastasis through Wnt/β-catenin-Mediated EMT Int J Biol Sci 2019 15(3): 636–646
Pingting Zhou, Yanyan Li, Bo Li, Meichao Zhang, Yuanhua Liu, Yuan Yao, Dong Li# （通讯作者） NMIIA promotes tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway and EMT in pancreatic cancer Oncogene 2019 38(27):5500-5515
Lei Bian, Yiling Meng, Meichao Zhang,Dong Li# （通讯作者） MRE11-RAD50-NBS1 complex alterations and DNA damage response: implications for cancer treatment Molecular Cancer 2019 18(1):169
Yanyan Li, Chun Yang, Pingting Zhou, Shijie Zhang, Yuan Yao, Dong Li# （通讯作者） Genome-scale analysis to identify prognostic markers and predict the survival of lung adenocarcinoma J Cell Biochem 2018 119(11):8909-8921
Pingting Zhou, Yanyan Li, Bo Li, Meichao Zhang, Ci Xu, Furao Liu, Lei Bian,Yuanhua Liu, Yuan Yao, Dong Li# （通讯作者） Autophagy inhibition enhances celecoxib-induced apoptosis in osteosarcoma Cell Cycle 2018 25:1-10
Furao Liu,Pingting Zhou,Qian Wang,Meichao Zhang,Dong Li# （通讯作者） The Schlafen family: complex roles in different cell types and virus replication Cell Biol Int 2018 42(1):2-8
Ping-Ting Zhou,Bo Li,Fu-Rao Liu,Mei-Chao Zhang,Qian Wang, Yan-Yan Li,Ci Xu,Yuan-Hua Liu,Yuan Yao,Dong Li# （通讯作者） Metformin is associated with survival benefit in pancreatic cancer patients with diabetes: a systematic review and meta-analysis Oncotarget 2017 8(15): 25242–25250
Pingting Zhou, Bo Li, Furao Liu, Meichao Zhang, Qian Wang, Yuanhua Liu, Yuan Yao, Dong Li# （通讯作者） The epithelial to mesenchymal transition (EMT) and cancer stem cells: implication for treatment resistance in pancreatic cancer Molecular Cancer 2017 16:52
Xiangyang Huang, Nanping Yang, Xuemei Ou, Dong Li, Zhongming Wang, Qibing Xie, Yongtao Chen, Hui Lin, Gen Yin and Fuqiang Wen Sequential activation of protein kinase C delta and JNK is required for interferon-alpha-induced expression of IFIT4 Cell Signal 2008 20(1):112-9
Ying Huang, Qian Zhao, Ci-Xiang Zhou, Zhi-Min Gu, Dong Li, Han-Zhang Xu, Peter J Sims, Ke-Wen Zhao, Guo-Qiang Chen Anti-leukemic role of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells Oncogene 2006 25(50):6618-27
Ke-Wen Zhao*, Dong Li* （共同第一作者）, Qian Zhao, Ying Huang, Silverman RH, Peter J Sims, Guo-Qiang Chen Interferon-α induced expression of phospholipid scramblase 1 through STAT1 requires the sequential activation of protein kinase Cδ & JNK J Biol Chem 2005 280(52):42707-14
Ke-Wen Zhao, Xi Li, Qian Zhao, Ying Huang, Dong Li, Zhen-Gang Peng, Wu-Zhong Shen, Ji Zhao, Quansheng Zhou, Zhu Chen, Peter J. Sims, Therese Wiedmer, and Guo-Qiang Chen Protein kinase Cδ mediates retinoic acid and phorbol myristate acetate–induced phospholipid scramblase 1 gene expression:its role in leukemic cell differentiation Blood 2004 104(12):3731-38