导师姓名： 姜虹 专业代码： 100217
性别： 女 专业名称： 麻醉学
培养单位： 附属第九人民医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师： 兼
联系方式： Email：drjianghongjy@163.com地址：上海制造局路639号（上海交通大学医学院附属第九人民医院麻醉科）
邮编： 200011 邮箱地址： drjianghongjy@163.com

研究方向 (点击浏览详细信息)
围术期困难气道管理、颅颌面外科麻醉管理及肺损伤机制研究
麻醉药物与认知功能障碍的研究
麻醉相关新型化合物和材料的研发

社会任职
上海市医学会麻醉科专科分会候任主任委员
中华医学会麻醉学分会气道管理学组副组长
中国高等教育学会医学教育专业委员会麻醉教育研究会理事
上海医学会危重病专科分会委员
中国药理学会麻醉药理分会委员
中华口腔医学会口腔麻醉学专业委员会前任主任委员
上海市卫生系列高级专业技术职务任职资格评审委员会麻醉医学组委员
中国医师协会麻醉学分会全国委员
国际牙医师学院院士
上海口腔医学会口腔麻醉学专委会前任主任委员
中国心胸血管麻醉学会医疗保险管理分会委员
上海医学会医疗鉴定专家库委员
上海口腔医学会理事
亚洲口腔麻醉学会联盟主任委员
上海市医师协会麻醉科医师分会委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 基于PETCO2感知的气管插管一体化智能装置的研发 上海市科学技术委员会科研计划项目 2018-04~2021-06 35万元 课题负责人
17DZ** 化学失能剂成分筛选和验证 上海市科学技术委员会科研计划项目 2017-07~2019-06 100万元 课题负责人
2016ZB0203-01 急诊与危重医学-头颈颌面部严重创伤和重症感染救治 上海市卫生计生系统重要薄弱学科建设计划 2016-06~2019-06 26万元 课题负责人
16XD** 七氟烷麻醉致脑发育期海马神经元树突棘发育异常的机制研究 上海市科委优秀学术带头人计划 2016-05~2019-04 40万元 课题负责人
** LSD1-Apelin-13在七氟烷诱导的孕早期胎儿神经系统毒性的作用及其机制研究 国家自然科学基金面上项目 2016-01~2019-12 57万元 课题负责人
** TLR4/HIF-1α干预对创伤失血性休克后急性肺损伤的作用及机制研究 国家自然科学基金面上项目 2013-01~2016-12 70万元 课题负责人
12ZR** TLR4/HIF-1α干预对创伤失血性休克后急性肺损伤的作用 上海市科委自然基金 2012-12~2014-12 10万元 课题负责人
异氟烷对创伤失血性休克肺损伤的保护作用及机制研究 上海市卫生局重点项目 2011-01~2013-12 10万元 课题负责人
HO/CO系统在异氟烷急性肺损伤保护作用中的地位 上海交通大学 2009-01~2011-12 10万元 课题负责人
07ZR14069 异氟烷预处理对急性肺损伤的保护作用及信号转导机制研究 上海市科委,自然基金 2007-11~2009-11 10万元 课题负责人
054051 围术期发生困难气道危险性及建立预测评估体系的研究 上海市卫生局,局级课题 2005-10~2007-12 3万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Zhang L, Xue Z, Liu Q, Liu Y, Xi S, Cheng Y, Li J, Yan J, Shen Y, Xiao C, Xie Z, Qiu Z, Jiang H （通讯作者） Disrupted folate metabolism with anesthesia leads to myelination deficits mediated by epigenetic regulation of ERMN EBioMedicine 2019 43:473-486
Zhang L, Yan J, Liu Q, Xie Z, Jiang H （通讯作者） LncRNA Rik-203 contributes to anesthesia neurotoxicity via microRNA-101a-3p and GSK-3β-mediated neural differentiation Sci Rep 2019 9(1): 6822
Li C, Peng J, Hu R, Yan J, Sun Y, Zhang L, Liu W, Jiang H （通讯作者） Safety and Efficacy of Ketamine Versus Ketamine-Fentanyl-Dexmedetomidine Combination for Anesthesia and Analgesia in Rats Dose Response 2019 17(1):**25902
Zhang L, Xue Z, Yan J, Wang J, Liu Q, Jiang H （通讯作者） LncRNA Riken-201 and Riken-203 modulates neural development by regulating the Sox6 through sequestering miRNAs Cell Prolif 2019 52(3):e12573
Yan J, Li J, Zhang L, Sun Y, Jiang J, Huang Y, Xu H, Jiang H （通讯作者）, Hu R. Nrf2 protects against acute lung injury and inflammation by modulating TLR4 and Akt signaling. Free Radic Biol Med. 2018 121:78-85
Cheng Y, Jiang Y, Zhang L, Wang J, Chai D, Hu R, Li C, Sun Y, Jiang H （通讯作者） Mesenchymal stromal cells attenuate sevoflurane-induced apoptosis in human neuroglioma H4 cells BMC Anesthesiol 2018 18(1):84
Zhou X, Zhang P, Luo W, Zhang L, Hu R, Sun Y, Jiang H （通讯作者） Ketamine induces apoptosis in lung adenocarcinoma cells by regulating the expression of CD69 Cancer Med 2018 7(3): 788-795.
Lv X, Lu Y, Tang YW, Jiang J, Yan J, Jiang H （通讯作者） Neurodevelopmental outcomes after a brief exposure to the inhaled anesthetic sevoflurane in young children undergoing palatoplasty Int J Clin Exp Med 2018 11(3): 2240-2247
Lv X, Yan J, Jiang J, Zhou XH, Lu Y, Jiang H （通讯作者） MicroRNA-27a-3p suppression of peroxisome proliferator-activated receptor-γ contributes to cognitive impairments resulting from sevoflurane treatment. J Neurochem. 2017 J Neurochem.
Lv X, Zhou X, Yan J, Jiang J, Jiang H. （通讯作者） Propofol inhibits LPS-induced apoptosis in lung epithelial cell line, BEAS-2B. Biomed Pharmacother. 2017 87:180-187.
Guo Y,Sun LL,Zhang JF,Li QF,Jiang H （通讯作者）,Jiang W Preventive effects of low-dose dexmedetomidine on postoperative cognitive function and recovery quality in elderly oral cancer patients Int J Clin Exp Med 2015 8(9):16183-16190
Hu R,Zhang Y,Yang XH,Yan J,Sun Y,Chen ZF,Jiang H （通讯作者） Isoflurane attenuates LPS-induced acute lung injury by targeting miR-155-HIF1-alpha Front Biosci 2015 20:139-56
Jiang J,Jiang H （通讯作者） Effect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer's disease MOLECULAR MEDICINE REPORTS 2015 12(1):3-12
Jiang J,Chen ZF,Liang B,Yan J,Zhang Y,Xu H,Huang Y,Jiang H （通讯作者） The change of circulating insulin like growth factor binding protein 7 levels may correlate with postoperative cognitive dysfunction Neurosci Lett 2015 588:125-30
Zhang Y,Yan J,Hu R,Sun Y,Ma YW,Chen ZF,Jiang H （通讯作者） Microglia are involved in pruritus induced by DNFB via the CX3CR1/p38 MAPK pathway Cell Physiol Biochem 2015 35(3):1023-33
Jiang J,Jiang H （通讯作者） Efficacy and adverse effects of memantine treatment for Alzheimer's disease from randomized controlled trials Neurol Sci 2015 36(9):1633-41
Yang YQ,Yan J,Huang Y,Xu H,Zhang Y,Hu R,Jiang J,Chen ZF,Jiang H （通讯作者） The cancer pain related factors affected by celecoxib together with cetuximab in head and neck squamous cell carcinoma Biomedicine & Pharmacotherapy 2015 70:181-9
Lu Y,Wang J,Yan J,Yang YQ,Sun Y,Huang Y,Hu R,Zhang Y,Jiang H （通讯作者） Sevoflurane attenuate hypoxia-induced VEGF level in tongue squamous cell carcinoma cell by upregulating the DNA methylation states of the promoter region Biomedicine & Pharmacotherapy 2015 71:139-45
Hu R,Chen ZF,Yan J,Li QF,Huang Y,Xu H,Zhang XP,Jiang H （通讯作者） Endoplasmic Reticulum Stress of Neutrophils Is Required for Ischemia/Reperfusion–Induced Acute Lung Injury The Journal of Immunology 2015 195(10):4802-9
Sun Y,Li QF,Yan J,Hu R,Jiang H （通讯作者） Isoflurane Preconditioning Promotes the Survival and Migration of Bone Marrow Stromal Cells Cell Physiol Biochem 2015 36(4):1331-1345
Zhang L,Zhang Y,Hu R,Yan J,Huang Y,Jiang J,Yang YQ,Chen ZF,Jiang H （通讯作者） Isoflurane Inhibits Embryonic Stem Cell Self-Renewal and Neural Differentiation Through miR-9/E-cadherin Signaling STEM CELLS AND DEVELOPMENT 2015 24(16):1912-1922
Jiang H,Hu R,Sun LL,Chai DD,Cao ZD,Li QF Critical role of toll-like receptor 4 in hypoxia-inducible factor 1α activation during trauma/hemorrhagic shock induced acute lung injury after lymph infusion in mice Shock 2014 42(3):271-8
Huang Y,Lu Y,Zhang L,Yan J,Jiang J,Jiang H （通讯作者） Perineural dexmedetomidine attenuate inflammation for sciatic nerve block in rats via NF-kB pathway Int J Mol Sci 2014 15:4049-4059
Xu R,Lu R,Jiang H （通讯作者）,Li QF,Sun Y,Xu H,Huang Y Meta-analysis of protective effect of sevoflurane on myocardium during cardiac surgery European Review for Medical and Pharmacological Sciences 2014 18:1058-1066
Wang Y,Zhu Y,Jiang H （通讯作者）,Huang Y Propofol and Dexmedetomidine for Monitored Anesthesia Care During Laser In Situ Keratomileusis Eye & Contact Lens 2014 40:12–16
Liu JX,Hu R,Sun Y,Jiang H （通讯作者） General anesthesia in fibrodysplasia ossificans progressive: a case report and clinical review Int J Clin Exp Med 2014 7(5):1474-1479
Yan J,Huang Y,Lu yi,Chen J,Jiang H （通讯作者） Repeated Administration of Ketamine can Induce Hippocampal Neurodegeneration and Long-Term Cognitive Impairment via the ROS/HIF-1α Pathway in Developing Rats Cell Physiol Biochem 2014 33:1715-1732
Sun Y,Lu Y,Huang Y,Jiang H （通讯作者） Pediatric video laryngoscope versus direct laryngoscope: a meta-analysis of randomized controlled trials Pediatric Anesthesia 2014 24:1056–1065
Yan J,Jiang H （通讯作者） Dual effects of ketamine: neurotoxicity versus neuroprotection in anesthesia for the developing brain J Neurosurg Anesthesiol 2014 26:155–160
Yan J,Li YR,Zhang Y,Lu Y,Jiang H （通讯作者） Repeated Exposure to Anesthetic Ketamine Can Negatively Impact Neurodevelopment in Infants: A Prospective Preliminary Clinical Study Journal of Child Neurology 2014 29(10):1333-1338
Sun Y,Lu Y,Huang Y,Jiang H （通讯作者） Is dexmedetomidine superior to midazolam as a premedication in children? A meta-analysis of randomized controlled trials Pediatr Anesth 2014 24:863-74
Hu R,Chen ZF,Yan J,Li QF,Huang Y,Xu H,Zhang X,Jiang H （通讯作者） Complement C5a exacerbates acute lung injury induced through autophagy-mediated alveolar macrophage apoptosis Cell Death and Disease 2014 5:e1330
Hu R,Jiang H （通讯作者） In reply: is dexmedetomidine or remifentanil alone an optimal sedation scheme for awake intubation? J Anesth 2013 27(4):629-30
Fang SD,Xu H,Lu JR,Zhu YS,Jiang H （通讯作者） Neuroprotection by the Kappa-Opioid Receptor Agonist, BRL52537, is Mediated via Up-Regulating Phosphorylated Signal Transducer and Activator of Transcription-3 in Cerebral Ischemia/Reperfusion Injury in Rats Neurochem Res 2013 38:2305-12
Chen J,Zhou JQ,Chen ZF,Huang Y,Jiang H （通讯作者） Efficacy and safety of dexmedetomidine versus propofol for the sedation of tube-retaining after oral maxillofacial surgery Journal of oral maxillofacial surgery 2013 72:285.e1-285.e7
Dong X,Hu R,Sun Y,Sun Y,Li QF,Jiang H （通讯作者） Isoflurane post-treatment improves pulmonary vascular permeability via upregulation of heme oxygenase-1 Experimental Lung Research 2013 39:295–303
Sun Y,Li QF,Zhang Y,Hu R,Jiang H （通讯作者） Isoflurane preconditioning increases survival of rat skin random-pattern flaps by induction of HIF-1α expression Cellular Physiology and Biochemistry 2013 31:579-591
Hu R,Xu H,Jiang H （通讯作者）,Zhang Y,Sun Y The role of TLR4 in the pathogenesis of indirect acute lung injury Frontiers in Bioscience 2013 18:1244-1255
Hu R,Liu JX,Jiang H （通讯作者） Dexmedetomidine versus remifentanil sedation during awake fiberoptic nasotracheal intubation: a double-blinded randomized controlled trial J Anesth 2013 27:211–217
Li QF,Xu H,Sun Y,Hu R,Jiang H （通讯作者） Induction of inducible nitric oxide synthase by isoflurane post-conditioning via hypoxia inducible factor-1α during tolerance against ischemic neuronal injury Brain Res 2012 27(1451):1-9
Lu Y,Jiang H （通讯作者） Meta-analysis: the importance of a proper search strategy Eur J Anaesthesiol 2012 29(12):300
Jiang H （共同第一作者）,Huang Y,Xu H,Hu R,Li QF Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats Acta Pharmacol Sin 2012 33(5):635-643
Jiang H,Huang Y,Xu H, Sun Y,Han N,Li QF Hypoxia inducible factor-1α is involved in the neurodegeneration induced by isoflurane in the brain of neonatal rats J Neurochem 2012 120(3):453-460
Sun Y,Liu JX,Zhu YS,Xu H,Huang Y,Jiang H （通讯作者） Nasotracheal intubation using the Blind Intubation Device in anaesthetised adults with Mallampati class 3: a comparison with the Macintosh laryngoscope Eur J Anaesthesiol 2011 28(11):774-780
Lu,Jiang H （通讯作者）,Zhu YS Airtraq laryngoscope versus conventional Macintosh laryngoscope: a systematic review and meta-analysis Anaesthesia 2011 66(12):1160-1167
Sun Y,Liu JX,Jiang H （通讯作者）,Zhu YS,Xu H,Huang Y Cardiovascular responses and airway complications following awake nasal intubation with blind intubation device and fibreoptic bronchoscope: a randomized controlled study Eur J Anaesthesiol 2010 27(5):461-7
Jiang H （共同第一作者）,Zhu YS,Xu H,Sun Y,Li QF Activation of hypoxia- inducible factor-1a via nuclear factor-kB in rats with chronic obstructive pulmonary disease Acta Biochim Biophys Sin 2010 42(6):483-488
Liu JX, Sun Y, Jiang H （通讯作者）, Zhu YS Airway management in a neonate with oral teratoma Pediatr Anaesth 2010 20(3):284-5
Jiang H （共同第一作者）,Zhu YS,Xu H,Sun Y,Li QF Inflammatory stimulation and hypoxia cooperatively activate HIF-1a in bronchial epithelial cells: involvement of PI3K and NF-kB Am J Physiol Lung Cell Mol Physiol 2010 298:660-9
Liu JX,Sun Y,Jiang H （通讯作者）,Zhu YS Retrograde conversion of oral to nasotracheal intubation using a suction catheter in a pediatric patient Pediatr Anesth 2009 19(7):709-11
He Z,Zhu Y,Jiang H （通讯作者） Inhibiting toll-like receptor 4 signaling ameliorates pulmonary fibrosis during acute lung injury induced by lipopolysaccharide: an experimental study Resp Res 2009 10(1):126-136
Li QF,Zhu YS,Jiang H （通讯作者）,Xu H,Sun Y Isoflurane preconditioning ameliorates endotoxin-induced acute lung injury and mortality in ratsfibrosis during acute lung injury induced by lipopolysaccharide: an experimental study Anesth Analg 2009 109(5):1591-7
Sun Y,Jiang H （通讯作者）,Zhu Y,Xu H,Huang Y Blind intubation device for nasotracheal intubation in 100 oral and maxillofacial surgery patients with anticipated difficult airways: a prospective evaluation Eur J Anaesthesiol 2009 26(9):746-51
Jiang H （通讯作者）,Sun Y,Zhu Y A useful device for difficult nasal tracheal intubation in China Eur J Anaesthesiol 2009 26(7):621-2
He ZY,Zhu YS,Jiang H （通讯作者） Toll-like receptor 4 mediates lipopolysaccharide-induced collagen secretion by phosphoinositide 3-kinase-akt pathway in fibroblasts during acute lung injury J Recept Signal Transduct Res 2009 29(2):119-25
Li Q,Zhu Y,Jiang H （通讯作者）,Xu H,Sun Y Heme oxygenase-1 mediates the anti-inflammatory effect of isofurane precondtioning in LPS-stimulated macrophages Acta Pharmacologica Sinica 2009 30(2):228-34
Sun Y,Jiang H （通讯作者）,Zhu YS Airway rescue with an esophageal airway in a child with a huge venous malformation in oral and maxillofacial region - a case report Pediatr Anesth 2009 19(6):633-5
Li Q,Zhu Y,Jiang H （通讯作者）,Xu H,Liu H Up-regulation of heme oxygenase-1 by isoflurane preconditioning during tolerance against neuronal injury induced by oxygen glucose deprivation Acta Biochim Biophys Sin 2008 40(9):803-10
Li QF,ZhuYS,Jiang H （通讯作者） Isoflurane preconditioning activates HIF-1alpha, iNOS and Erk1/2 and protects against oxygen-glucose deprivation neuronal injuryinduced by lipopolysaccharide: an experimental study Brain Res 2008 15(1245):26-35