导师姓名： 徐明 专业代码： 100214
性别： 男 专业名称： 肿瘤学
培养单位： 附属第九人民医院 三级学科/
专业领域：
导师类型： 硕士生导师 专业学位导师：
联系方式： mingxu.msu@gmail.com
邮编： 201999 邮箱地址： mingxu@shsmu.edu.cn

研究方向 (点击浏览详细信息)
肿瘤分子生物学

社会任职

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** Fbxo45/STEP介导肺癌细胞ERK信号持续激活的功能及机制 国家自然科学基金面上项目 2017-01~2020-12 56万元 课题负责人
** 新信号轴miR-27a*-FBXO45-SIP1调控前列腺癌发生发展的分子机制 国家自然科学基金青年项目 2014-01~2016-12 23万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Qiang Fan, Qian Wang, Renjie Cai, Haihua Yuan, Ming Xu （通讯作者） he ubiquitin system: orchestrating cellular signals in non-small-cell lung cancer Cellular & Molecular Biology Letters 2020 25: 1
Danhong Wu, Wenmei Lu, Zhenyu Wei, Ming Xu （通讯作者）, Xueyuan Liu Neuroprotective Effect of Sirt2-specific Inhibitor AK-7 Against Acute Cerebral Ischemia is P38 Activation-dependent in Mice NEUROSCIENCE 2018 374: 61–69
Bo Huang, Weiyang Cai, Qian Wang, Feng Liu, Ming Xu （通讯作者）, Yanjie Zhang Gankyrin Drives Malignant Transformation of Gastric Cancer and Alleviates Oxidative Stress via mTORC1 Activation Oxidative Medicine and Cellular Longevity 2018 2018: **
Haihua Yuan, Rong Deng, Xian Zhao, Ran Chen, Guofang Hou, Hailong Zhang, Yanli Wang, Ming Xu,Bin Jiang, Jianxiu Yu SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis Molecular Cancer 2017 16:e157
Jiangmin Zhaoa, Le Li, Qian Wang, Hongxiu Han, Qing Zhan, Ming Xu （通讯作者） CircRNA Expression Profile in Early-Stage Lung Adenocarcinoma Patients Cell Physiol Biochem 2017 44:2138-2146
Changhong Zhu, Cheng Chen, Ran Chen, Rong Deng, Xian Zhao, Hailong Zhang, Jinzhuo Duo, Qin Chen, Hui Jin, Yanli Wang, Jian Huang, Ming Xu （通讯作者）, Jianxiu Yu K259-SUMOylation of DGCR8 promoted by p14ARF exerts a tumor-suppressive function Journal of Molecular Cell Biology 2016 8(5):456–458
Cheng Chen, Changhong Zhu, Jian Huang, Xian Zhao, Rong Deng, Hailong Zhang, Jinzhuo Dou, Qin Chen, Ming Xu, Haihua Yuan, Yanli Wang, Jianxiu Yu SUMOylation of TARBP2 regulates miRNA/siRNA efficiency Nature Comunication 2015 6: 8899
Changhong Zhu, Cheng Chen, Jian Huang, Hailong Zhang, Xian Zhao, Rong Deng, Jinzhuo Dou, Hui Jin, Ran Chen, Ming Xu, Qin Chen, Yanli Wang, Jianxiu Yu SUMOylation at K707 of DGCR8 controls direct function of primary microRNA Nucleic Acids Research 2015 43(16): 7945–7960
Ming Xu, Changhong Zhu, Xian Zhao, Cheng Chen, Hailong Zhang, Haihua Yuan, Rong Deng, Jinzhuo Dou, Yanli Wang, Jian Huang, Qin Chen, Bin Jiang, Jianxiu Yu Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors Oncotarget 2015 6(2):979-994
Yingying Qu, Qin Chen, Xueping Lai, Changhong Zhu, Cheng Chen, Xian Zhao, Rong Deng, Ming Xu, Haihua Yuan, Yanli Wang, Jianxiu Yu, Jian Huang SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1 Molecular Cancer 2014 13:e95
Miaojun Zhu, Qin Chen, Xin Liu, Qian Sun, Xian Zhao, Rong Deng, Yanli Wang, Jian Huang, Ming Xu, Jianshe Yan, Jianxiu Yu lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI FEBS J 2014 281:3766–3775
X Liu, Q Chen, J Yan, Y Wang, C Zhu, C Chen, X Zhao, M Xu, Q Sun, R Deng, H Zhang, Y Qu, J Huang, B Jiang, J Yu MiRNA-296-3p-ICAM-1 axis promotes metastasis of prostate cancer by possible enhancing survival of natural killer cell-resistant circulating tumour cells Cell Death and Disease 2013 4: e928
Ming Xu, Scott D. Fitzgerald, Huanmin Zhang, Darrin M. Karcher, Mohammad Heidari Very virulent plus strains of MDV induce an acute form of transient paralysis in both susceptible and resistant chicken lines Viral Immunology 2012 25(4):306-323
Ming Xu, Huanmin Zhang, Lucy Lee, Hongwei Gao, Shayan Sharif, Robert F. Silva, and Mohammad Heidari Gene Expression Profiling in rMd5- and rMd5Δmeq-Infected Chickens Avian Diseases 2011 55(3):358-367
M Xu, S Chang, Z Ding, H Gao, J Wan, W Liu, L Liu, Y Gao, J Xu Genomic analysis of Newcastle disease virus strain NA-1 isolated from geese in China Archives of Virology 2008 153:1281