导师姓名： 朱亚琴 专业代码： 100302
性别： 女 专业名称： 口腔临床医学
培养单位： 附属第九人民医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市黄浦区瞿溪路500号上海第九人民医院口腔综合科
邮编： 200011 邮箱地址： zyq1590@163.com

研究方向 (点击浏览详细信息)
牙病综合治疗的基础和临床研究
口腔疾病与全身系统性疾病的关系
牙髓干细胞与牙髓再生研究

社会任职
上海市口腔医学会理事
中华口腔医学会口腔急诊专业委员会主任委员
中华口腔医学会全科口腔医学专业委员会副主任委员
上海市黄浦区医学会口腔学组组长
上海市口腔医学会全科口腔医学专业委员会主任委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
20**3 DFO促CXCR4阳性牙髓细胞修复能力的研究 高等学校博士学科点专项科研基金（博导类） 2014-01~2014-12 12万元 课题负责人
** 缺氧介导内质网应激调控牙髓干细胞成牙本质分化及其机制 国家自然基金面上项目 2013.1.1~2016.12.30 70万元 课题负责人
09ZZ116 人牙髓CXCR4＋细胞分选、鉴定和增殖分化研究 上海市教委 2009-01~2011-12 15万元 课题负责人
2008-0890-09 人牙髓CXCR4+细胞的筛选、鉴定和诱导分化 国家教育部出国留学人员基金 2008.11.1~2009.12.30 3万元 课题负责人
08JC** SDF-1/CXCR4轴在修复性牙本质形成中的作用机理研究 上海市科委基础研究重点项目 2008.10.1~2010.9.30 30万元 课题负责人
044062 根尖周状况和根管治疗质量的X线影像分析 上海市卫生局,局级课题 2005-01~2007-04 3万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Ya Qin Zhu,Ryan M. Song,Helena H. Ritchie Differential expression between "DSP-only" and DSP-PP523 transcripts in rat molar teeth Archives of Oral Biology 2017 Oct;82:33-37
Xuan Wang,Tian Tian Wu,Long Jing,Rong Du,Ya Qin Zhu （通讯作者） Deferoxamine-induced migration and odontoblast differentiation via ROS-dependent autophagy in dental pulp stem cells Cell Physiol Biochem 2017 43:2535-2547
Sheng Ding, Ruiqing Zhou,Yaqin Zhu （通讯作者） Structure of the 14-3-3-LKB1 fusion protein provides insight into a novel ligand-binding mode of 14-3-3 Acta Cryst 2015 F71.1114-1119
Ya Yang, NL Rhodus,FG Ondrey,BRK Wuertz,Xiaobing Chen,Yaqin Zhu （通讯作者） Quantitative Proteomic Analysis of Oral Brush Biopsies Identifies Secretory Leukocyte Protease Inhibitor as a Promising,Mechanism-Based Oral Cancer Biomarker. PLOS ONE 2014 9(4):e95389
Long jiang,Wei-wei Peng, Li-fen Li,Rong Du,Tian-tian Wu, jun-jun Zhao,Ya Yang, Dong-li Qu,Ya-qin Zhu （通讯作者） Effects of Deferoxamine on the Repair Ability of Dental Pulp Cells In Vitro. J Endodon 2014 40(8):1100-1104
Jiang Tao,Suxiong Tao,Junli Han,Zhujun Zhou,Xiaoping Zhang,Haining Wang,Rongji Chen,Fang ji,Yaqin Zhu. （通讯作者） RECQL1 Plays an Important Role in the Development of Tongue Squamous Cell Carcinoma. Cell Physiol Biochem 2014 33:1579-1590
Yanyan Han,Sisu Mo,long jiang,Yaqin Zhu （通讯作者） Effect of antioxidants on the microleakage of composite resin restorations after externai tooth bleaching. European Journal of dentistry 2014 8(2):147-153
Rong Du, Tiantian Wu, Wenjuan Liu, Lifen Li, LongJiang, Weiwei Peng, Jiang Chang,Yaqin Zhu （通讯作者） Role of the Extracellular Signal-regulated kinase 1/2 pathway in Driving Tricalcium Silicate-induced Proliferation and Biomineralization of Human Dental Pulp Cells in Vitro. J Endodon 2013 39(8):1023-1029
Tiantian Wu, Lifen Li, Rong Du,Long Jiang, Yaqin Zhu （通讯作者） Hydrogen Peroxide Induces Apoptosis in Human Dental pulp Cells via Caspase-9 Dependent Pathway. J Endodon 2013 39(9):1151-1155
Ya Yang,Yue-xiu Li,Xi Yang,Long Jiang,Zuo-jun Zhou,Ya-qin Zhu （通讯作者） Progress risk assessment of oral premalignant lesions with saliva miRNA analysis BMC Cancer 2013 13:129
Sheng Ding,Ruiqing Zhou,Yaqin Zhu （通讯作者） Crystallization and preliminary crystallographic analysis of the chimeric protein LKB1–14-3-3ζ. Acta Cryst. F 2013 69:1371-1373
Long Jiang, Wei-Wei Peng, Li-Fen Li, Ya Yang,Ya-Qin Zhu （通讯作者） Isolation and Identification of CXCR4-positive Cells fromHuman Dental Pulp Cells J Endodon 2012 38(6):791-795
Li-Fen Li, Ya-Qin Zhu （通讯作者）, Long Jiang, Wei-Wei Peng Increased autophagic activity in senescent human dental pulp cells Int Endod J 2012 45(12);1074-1079
Jiang Tao, Fang Ji, Baojun Liu, Feng Wang, Feng Dong, Yaqin Zhu （通讯作者） .Improvement of deficits by transplantation of lentiviralvector-modified human amniotic mesenchymal cells aftercerebral ischemia in rats .Brain Research 2012 1448:1-10
Jiang Tao, Fang Ji, Feng Wang, Baojun Liu, Yaqin Zhu （通讯作者） Neuroprotective effects of progranulin in ischemic mice Brain Research 2012 1436:130-136
Long Jiang, Wei-Wei Peng, Li-Fen Li, Ya Yang,Ya-Qin Zhu. （通讯作者） Proliferation and Multilineage Potential of CXCR4-positiveHuman Dental Pulp Cells In Vitro J Endodon 2012 38(5):642-647
Wei-wei Peng, Wei-ning Liu, Wan-yin Zhai,Long Jiang,Li-fen Li, Jiang Chang,Ya-qin Zhu （通讯作者） Effect of tricalcium silicate on the proliferation and odontogenic differentiation of human dental pulp cells J Endodon 2011 37(9):1240-1246
Ya Yang,Jian-ping Ge,Long Jiang,Li-feng Li,Ya-qin Zhu （通讯作者） Modulation of growth and angiogenic potential of oral squamous carcinoma cells in vitrousing salvinolic acid .B.BMC complementary and Alternative Medicine 2011 11:54-54
Liu WN, Chang J, Zhu YQ, Zhang M. Effect of tricalcium aluminate on the properties of tricalcium silicate-tricalcium aluminate mixtures: setting time, mechanical strength and biocompatibility. Int Endod J. 2011 44(1):41-50
Xu-na Tang, Ya-qin Zhu （共同第一作者）, Cynthia L. Marcelo, Helena H. Ritchie Expression of mineralized tissue associated proteins: Dentin sialoprotein andphosphophoryn in rodent hair follicles Journal of Dermatological Science 2011 64:92-98
Ya Yang,Ya-qin Zhu （通讯作者）,Long Jiang,Li-fen Li Thalidomide induces apopotosis in human oral squamous cell carcinoma cell line with altered expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) Oral Oncology 2011 47:927-928
Li-fen Li,Ya-qin Zhu （通讯作者）,Long Jiang,Wei-wei Peng,Helena H. Ritchie Hypoxia promote mineralization of human dental pulp cells J Endodon 2011 37(6):799-802
Liu WN, Chang J, Zhu YQ, Zhang M Effect of tricalcium aluminate on the properties of tricalcium silicate-tricalcium aluminate mixtures: setting time, mechanical strength and biocompatibility Int Endod J 2011 44(1):41-50
Xia WW, Zhu YQ, Wang XY Six cases report of differential diagnosis of periapical diseases. Int J Oral Sci 2011 3(3):153-159
Ya Yang,Lu-dong Zhang,Jian-ping Ge,Ya-qin Zhu （通讯作者） Prevalence of 3-root first permanent molars among a Shanghai Chinese population Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology 2010 110(5):101-101
Long Jiang, Ya-Qin Zhu （通讯作者）, Rong Du The Expression and Role of Stromal Cell–derived Factor-1α–CXCR4 Axis in Human Dental Pulp J Endodon 2008 34(8):939-944